Page last updated: 2024-12-06

stearyl stearate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Occurs in Manufacturing Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Stearyl stearate is an ester formed by the reaction of stearic acid with stearyl alcohol. It is a white, waxy solid that is insoluble in water but soluble in organic solvents. Stearyl stearate is a common ingredient in cosmetics and personal care products, where it acts as an emollient, thickener, and lubricant. It is also used in pharmaceuticals as an excipient and in food as a release agent. Stearyl stearate is generally considered safe for use in these applications. The synthesis of stearyl stearate involves the esterification of stearic acid with stearyl alcohol in the presence of a catalyst, such as sulfuric acid. The reaction is typically carried out at elevated temperatures. Stearyl stearate has a variety of effects on the skin, including improving moisture retention, reducing skin friction, and providing a smooth and soft feel. Its importance lies in its ability to enhance the texture and feel of products, as well as its safety profile. Stearyl stearate is studied to understand its effects on the skin, to optimize its use in various applications, and to develop new and improved formulations. '

octadecyl stearate: found in psoriatic nail, but not in normal nails [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID17720
SCHEMBL ID42773
MeSH IDM0523920

Synonyms (41)

Synonym
octadecanoic acid, octadecyl ester
octadecyl octadecanoate
stearyl stearate, >=98.0% (gc)
octadecyl stearate
stearyl stearate
2778-96-3
stearic acid stearyl ester
stearic acid octadecyl ester
octadecanoic acid octadecyl ester
5wx2egd0dk ,
stearic acid, stearyl ester
octadecanoyic acid, octadecyl ester
einecs 220-476-5
unii-5wx2egd0dk
we(18:0/18:0)
LMFA07010054
octadecanyl octadecanoate
FT-0634483
stearyl stearate [inci]
SCHEMBL42773
DTXSID5062639
hetester 412
lexol ss
fe 78-18
liponate ss
loxiol g 30
stearic acid, octadecyl ester
cyclochem ss
ritachol ss
1-octadecyl octadecanoate
emalex cc-18
AKOS024438267
mfcd00056225
stearyl stearate, analytical standard
stearyl stearate, ~99%
J-016884
E79230
Q27262974
BS-49287
CS-0185669
HY-W127437

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" The Expert Panel concluded that stearyl heptanoate, stearyl caprylate, stearyl palmitate, stearyl stearate, stearyl behenate, and stearyl olivate are safe in the present practices of use and concentration."( Safety assessment of stearyl heptanoate and related stearyl alkanoates as used in cosmetics.
Andersen, FA; Belsito, DV; Bergfeld, WF; Fiume, MM; Hill, RA; Klaassen, CD; Liebler, D; Marks, JG; Shank, RC; Slaga, TJ; Snyder, PW,
)
0.35
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Occurs in Manufacturing (3 Product(s))

Product Categories

Product CategoryProducts
en:pineapple1
Beauty & Personal Care2

Products

ProductBrandCategoryCompounds Matched from IngredientsDate Retrieved
Daeng Gi Meo Ri Medicinal Herb Hair Color - Black -- 1 KitDaeng Gi Meo RiBeauty & Personal Carebutylene glycol, P-aminophenol, PCA, ceteth-20, cetyl alcohol, citronellol, dioleyl phosphate, behenyl alcohol, lauryl alcohol, disodium EDTA, ethanolamine, geraniol, hexyl cinnamal, hydroxycitronellal, butylphenyl methylpropional, limon- ene, linalool, myristic acid, myristyl alcohol, oleyl alcohol, palmitic acid, palmitic acid, phenacetin, resorcinol, sodium benzoate, stearic acid, stearyl alcohol, stearyl stearate, threonine2024-11-29 10:47:42
Daeng Gi Meo Ri Medicinal Herb Hair Color - Natural Brown -- 1 KitDaeng Gi Meo RiBeauty & Personal Carebutylene glycol, P-aminophenol, PCA, ceteth-20, cetyl alcohol, citronellol, dioleyl phosphate, behenyl alcohol, lauryl alcohol, disodium EDTA, ethanolamine, geraniol, hexyl cinnamal, hydroxycitronellal, butylphenyl methylpropional, limon- ene, linalool, myristic acid, myristyl alcohol, oleyl alcohol, palmitic acid, palmitic acid, phenacetin, resorcinol, sodium benzoate, stearic acid, stearyl alcohol, stearyl stearate, threonine2024-11-29 10:47:42

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 37.58

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index37.58 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.09 (4.65)
Search Engine Demand Index47.86 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (37.58)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (16.67%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (83.33%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]