antipyrine has been researched along with Psoriasis in 11 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The kinetic parameters of antipyrine obtained from saliva samples and the appearance of major antipyrine metabolites (4-hydroxyantipyrine, norantipyrine and 3-hydroxymethylantipyrine) in urine samples were measured in 10 patients with psoriasis (six nonsmokers and four smokers) and in 20 healthy subjects (11 nonsmokers and nine smokers)." | 7.67 | Antipyrine clearance and metabolism in patients with psoriasis. ( Chiba, K; Ishizaki, T; Kubota, K; Nakagawa, A; Nakamura, K; Takagi, A, 1986) |
| "Antipyrine clearance was determined in 41 psoriatics and age-sex matched controls, using sequential measurements of salivary concentration." | 5.27 | Reduction of antipyrine clearance in psoriasis. ( Keys, B; Marsden, JR; Rawlins, MD; Shuster, S; Williams, FM, 1984) |
| "Salivary antipyrine clearance was measured in 15 patients with psoriasis receiving methotrexate and related to liver biopsy changes and routine liver function tests, to determine whether antipyrine clearance could be used as a non-invasive method for monitoring liver function." | 3.67 | The use of antipyrine clearance to measure liver damage in psoriatic patients receiving methotrexate. ( Collins, M; Lawrence, CM; Paramsothy, J; Sharif, H; Shaw, P; Strange, R, 1988) |
| "The kinetic parameters of antipyrine obtained from saliva samples and the appearance of major antipyrine metabolites (4-hydroxyantipyrine, norantipyrine and 3-hydroxymethylantipyrine) in urine samples were measured in 10 patients with psoriasis (six nonsmokers and four smokers) and in 20 healthy subjects (11 nonsmokers and nine smokers)." | 3.67 | Antipyrine clearance and metabolism in patients with psoriasis. ( Chiba, K; Ishizaki, T; Kubota, K; Nakagawa, A; Nakamura, K; Takagi, A, 1986) |
| "Antipyrine clearance was determined in 41 psoriatics and age-sex matched controls, using sequential measurements of salivary concentration." | 1.27 | Reduction of antipyrine clearance in psoriasis. ( Keys, B; Marsden, JR; Rawlins, MD; Shuster, S; Williams, FM, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (90.91) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CIMITAN, O | 1 |
| PACCHIANI, G | 1 |
| Marsden, JR | 1 |
| Williams, FM | 1 |
| Keys, B | 2 |
| Rawlins, MD | 2 |
| Shuster, S | 2 |
| Chapman, PH | 1 |
| Moss, C | 1 |
| Brockmeyer, NH | 1 |
| Frühauf, S | 1 |
| Mertins, L | 1 |
| Barthel, B | 1 |
| Goos, M | 1 |
| Chichenina, IV | 2 |
| Birnie, GG | 1 |
| Fitzsimons, CP | 1 |
| Czarnecki, D | 1 |
| Cooke, A | 1 |
| Scobie, G | 1 |
| Brodie, MJ | 1 |
| Khakimov, ZZ | 1 |
| Rakhmatov, AB | 1 |
| Zalialieva, MV | 1 |
| Paramsothy, J | 1 |
| Strange, R | 1 |
| Sharif, H | 1 |
| Collins, M | 1 |
| Shaw, P | 1 |
| Lawrence, CM | 1 |
| Kubota, K | 1 |
| Ishizaki, T | 1 |
| Chiba, K | 1 |
| Takagi, A | 1 |
| Nakagawa, A | 1 |
| Nakamura, K | 1 |
| Akovbian, VA | 1 |
| Krakovskiĭ, ME | 1 |
| Ashirmetov, AKh | 1 |
| Klemp, P | 1 |
11 other studies available for antipyrine and Psoriasis
| Article | Year |
|---|---|
[Parenteral administration of associated salicylic acid-resorcinol and antipyrine in the treatment of psoriasis].
Topics: Analgesics; Antipyrine; Humans; Psoriasis; Resorcinols; Salicylic Acid | 1951 |
Reduction of antipyrine clearance in psoriasis.
Topics: Adolescent; Adult; Aged; Antipyrine; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Ps | 1984 |
Antipyrine clearance in psoriasis.
Topics: Adult; Antipyrine; Female; Humans; Male; Middle Aged; Psoriasis; Saliva; Smoking | 1981 |
Effects of antipsoriatic therapies on hepatic microsomal enzyme activity in patients with psoriasis.
Topics: Administration, Topical; Anthralin; Anti-Inflammatory Agents; Antipyrine; Cytochrome P-450 Enzyme In | 1998 |
[The function of the monooxygenase system of the liver in patients with psoriasis].
Topics: Adolescent; Adult; Antipyrine; Benzhydryl Compounds; Chronic Disease; Drug Therapy, Combination; Enz | 1989 |
Hepatic metabolic function in patients receiving long-term methotrexate therapy: comparison with topically treated psoriatics, patient controls and cirrhotics.
Topics: Aged; Alkaline Phosphatase; Antipyrine; Female; gamma-Glutamyltransferase; Humans; Indocyanine Green | 1985 |
[Interrelation of monooxygenase activity and the function of the immune system in psoriasis patients].
Topics: Adult; Antipyrine; Chronic Disease; Female; Humans; Immune System; Immunity, Cellular; Liver; Male; | 1988 |
The use of antipyrine clearance to measure liver damage in psoriatic patients receiving methotrexate.
Topics: Adult; Antipyrine; Biopsy; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Dise | 1988 |
Antipyrine clearance and metabolism in patients with psoriasis.
Topics: Aged; Aged, 80 and over; Antipyrine; Aryl Hydrocarbon Hydroxylases; Edaravone; Female; Half-Life; Hu | 1986 |
[Testing the monooxygenase enzyme system of the liver using the antipyrine test in psoriasis patients].
Topics: 5-Methoxypsoralen; Adolescent; Adult; Antipyrine; Female; Ficusin; Furocoumarins; Humans; Male; Meth | 1986 |
Subcutaneous blood flow in psoriasis.
Topics: Adolescent; Adult; Aged; Antipyrine; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Psoria | 1985 |