Page last updated: 2024-10-19

inositol and Psoriasis

inositol has been researched along with Psoriasis in 12 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

Research Excerpts

ExcerptRelevanceReference
"To determine whether inositol supplements improve the psoriasis of patients on lithium therapy."9.11The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. ( Allan, SJ; Herd, RM; Kavanagh, GM; Savin, JA, 2004)
" However, chronic use and overdose can lead to other severe adverse effects."5.91Nutraceutical combination ameliorates imiquimod-induced psoriasis in mice. ( Bhuvarahamurthy, S; Kalaiyazhagan, A; Meganathan, J; Ramamoorthy, R; Venugopal, B; Vijayapoopathi, S, 2023)
"Psoriasis is an autoregulated immune and inflammation-based skin disease affecting approximately 3-4% of the worldwide population."5.51D-Pinitol Ameliorates Imiquimod-Induced PsoriasisLike Skin Inflammation in a Mouse Model via the NF-κB Pathway. ( Ai, D; Feng, S; Liu, Y; Ma, J; Yang, X, 2019)
"To determine whether inositol supplements improve the psoriasis of patients on lithium therapy."5.11The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. ( Allan, SJ; Herd, RM; Kavanagh, GM; Savin, JA, 2004)
" However, chronic use and overdose can lead to other severe adverse effects."1.91Nutraceutical combination ameliorates imiquimod-induced psoriasis in mice. ( Bhuvarahamurthy, S; Kalaiyazhagan, A; Meganathan, J; Ramamoorthy, R; Venugopal, B; Vijayapoopathi, S, 2023)
"Psoriasis is an autoregulated immune and inflammation-based skin disease affecting approximately 3-4% of the worldwide population."1.51D-Pinitol Ameliorates Imiquimod-Induced PsoriasisLike Skin Inflammation in a Mouse Model via the NF-κB Pathway. ( Ai, D; Feng, S; Liu, Y; Ma, J; Yang, X, 2019)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's3 (25.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Vijayapoopathi, S1
Ramamoorthy, R1
Meganathan, J1
Kalaiyazhagan, A1
Bhuvarahamurthy, S1
Venugopal, B1
Ma, J1
Feng, S1
Ai, D1
Liu, Y1
Yang, X1
Owczarczyk-Saczonek, A1
Czerwińska, J1
Wygonowska, E1
Kasprowicz-Furmańczyk, M1
Placek, W1
Sitter, B1
Johnsson, MK1
Halgunset, J1
Bathen, TF1
Forkel, S1
Schön, M1
Hildmann, A1
Claßen, A1
John, SM1
Danker, K1
Schön, MP1
WELSH, AL1
EDE, M1
MAIZBERMEJO, S1
Allan, SJ1
Kavanagh, GM1
Herd, RM1
Savin, JA1
CRAVINI, F1
Grisaru, N1
Belmaker, RH1
Fuga, GC1
Nini, G1
Guarneri, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Study of Foot-skin Microbiome and Metabolomics of Thai Naval Cadets With Pitted Keratolysis[NCT04781036]250 participants (Anticipated)Interventional2023-01-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for inositol and Psoriasis

ArticleYear
D-chiro-inositol as a treatment in plaque psoriasis: A randomized placebo-controlled clinical trial.
    Dermatologic therapy, 2021, Volume: 34, Issue:1

    Topics: Antioxidants; Double-Blind Method; Humans; Inositol; Psoriasis

2021
The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial.
    The British journal of dermatology, 2004, Volume: 150, Issue:5

    Topics: Adult; Antimanic Agents; Bipolar Disorder; Cross-Over Studies; Dietary Supplements; Double-Blind Met

2004

Other Studies

10 other studies available for inositol and Psoriasis

ArticleYear
Nutraceutical combination ameliorates imiquimod-induced psoriasis in mice.
    Chemical biology & drug design, 2023, Volume: 102, Issue:6

    Topics: Animals; Cannabidiol; Dietary Supplements; Disease Models, Animal; Erythema; Humans; Imiquimod; Inos

2023
D-Pinitol Ameliorates Imiquimod-Induced PsoriasisLike Skin Inflammation in a Mouse Model via the NF-κB Pathway.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2019, Volume: 38, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Imiquimod; Inflammation; Inositol; Male; Mice; Mice, Inbred BALB

2019
Metabolic changes in psoriatic skin under topical corticosteroid treatment.
    BMC dermatology, 2013, Aug-14, Volume: 13

    Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Aged; Biomarkers; Biopsy; Choline; Female;

2013
Inositoylated platelet-activating factor (Ino-C2-PAF) modulates dynamic lymphocyte-endothelial cell interactions and alleviates psoriasis-like skin inflammation in two complementary mouse models.
    The Journal of investigative dermatology, 2014, Volume: 134, Issue:10

    Topics: Animals; Apoptosis; Cell Communication; Cells, Cultured; Disease Models, Animal; E-Selectin; Endothe

2014
An appraisal of the therapeutic effect of riboflavin in psoriasis.
    A.M.A. archives of dermatology, 1957, Volume: 76, Issue:5

    Topics: Coenzymes; Humans; Inositol; Psoriasis; Riboflavin

1957
[PSORIASIS].
    Medicina espanola, 1963, Volume: 50

    Topics: Adrenal Cortex Hormones; Aminopterin; Chlorpromazine; Coal Tar; Diet; Diet Therapy; Humans; Inositol

1963
[First clinical experiences with the use of inositol].
    Minerva medica, 1950, Mar-24, Volume: 41, Issue:14

    Topics: Hepatitis; Humans; Inositol; Liver; Psoriasis

1950
Lithium dosage and inositol levels.
    The British journal of psychiatry : the journal of mental science, 1994, Volume: 164, Issue:1

    Topics: Bipolar Disorder; Dose-Response Relationship, Drug; Humans; Inositol; Lithium; Male; Middle Aged; Ps

1994
[Comparative evaluation of the action of 2 vasodilator drugs. Capillaroscopic study].
    Giornale italiano di dermatolotia. Minerva dermatologica, 1971, Volume: 46, Issue:6

    Topics: Adolescent; Adult; Blood Vessels; Capillaries; Child; Ethanolamines; Female; Humans; Inositol; Lupus

1971
[Therapeutic trials and laboratory results in psoriasis treated with products with normolipemic and eudermic action].
    Minerva medica, 1971, Feb-21, Volume: 62, Issue:15

    Topics: Duodenum; Fatty Acids, Essential; Humans; Inositol; Liver Extracts; Pancreatic Extracts; Psoriasis;

1971