theophylline has been researched along with Psoriasis in 23 studies
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We observed two patients on theophylline therapy with concomitant severe psoriasis and a two- to threefold greater theophylline clearance than that reported in healthy, nonsmoking adults." | 7.68 | Altered theophylline metabolism in patients with psoriasis. ( Barbour, MM; Cwik, MJ; Fiedler, VC; Fischer, JH; Micali, G; West, DP, 1990) |
| "We observed two patients on theophylline therapy with concomitant severe psoriasis and a two- to threefold greater theophylline clearance than that reported in healthy, nonsmoking adults." | 3.68 | Altered theophylline metabolism in patients with psoriasis. ( Barbour, MM; Cwik, MJ; Fiedler, VC; Fischer, JH; Micali, G; West, DP, 1990) |
| " It is postulated that the basic intrinsic abnormality of neutrophil function in psoriasis could be caused by a decreased cyclic AMP/cyclic GMP ratio, similar to the decreased cyclic AMP/cyclic GMP ratio found in the lesional epidermis of this disease." | 3.66 | Neutrophil chemotaxis in psoriasis. ( Bar-Eli, M; Callily, R; Cohen, H; Wahba, A, 1979) |
| "Theophylline and caffeine were more potent than dyphylline." | 1.28 | Xanthines inhibit 3T3 fibroblast proliferation. ( Levi-Schaffer, F; Touitou, E, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (82.61) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Papakostantinou, E | 1 |
| Xenos, K | 1 |
| Markantonis, SL | 1 |
| Druska, S | 1 |
| Stratigos, A | 1 |
| Katsambas, A | 1 |
| Iizuka, H | 2 |
| Umeda, K | 1 |
| Koizumi, H | 1 |
| Aoyagi, T | 1 |
| Miura, Y | 1 |
| Duell, EA | 3 |
| Guilhou, JJ | 1 |
| Andary, M | 1 |
| Clot, J | 1 |
| Rakhmatov, AB | 1 |
| Bilash, NV | 1 |
| Averkiev, VL | 1 |
| Dunaeva, LP | 1 |
| Reimer, G | 1 |
| Mentzer, M | 1 |
| Gottschalk, K | 1 |
| Neufahrt, A | 1 |
| Raynaud, F | 1 |
| Gerbaud, P | 1 |
| Evain-Brion, D | 1 |
| Wahba, A | 1 |
| Cohen, H | 2 |
| Bar-Eli, M | 1 |
| Callily, R | 1 |
| Verbenko, EV | 1 |
| Goncharova, LI | 1 |
| Petrova, IL | 1 |
| Shamina, GE | 1 |
| Voorhees, JJ | 2 |
| Yoshikawa, K | 1 |
| Adachi, K | 2 |
| Halprin, KM | 3 |
| Levine, V | 2 |
| Posternak, F | 1 |
| Posternak, T | 1 |
| Orusco, M | 1 |
| Cehovic, G | 1 |
| Laugier, P | 1 |
| Parker, CW | 1 |
| Kennedy, S | 1 |
| Eisen, AZ | 1 |
| Iancu, L | 1 |
| Shneur, A | 1 |
| Berenbeĭn, BA | 1 |
| Mikhaĭlov, GS | 1 |
| Shumaĭ, NI | 1 |
| Texier, L | 1 |
| Gauthier, MO | 1 |
| Gauthier, Y | 1 |
| Tamisier, JM | 1 |
| Delaunay, MM | 1 |
| Levi-Schaffer, F | 1 |
| Touitou, E | 1 |
| West, DP | 1 |
| Fischer, JH | 1 |
| Barbour, MM | 1 |
| Cwik, MJ | 1 |
| Micali, G | 1 |
| Fiedler, VC | 1 |
| Wright, RK | 1 |
| Mandy, SH | 1 |
| Hsia, SL | 1 |
| Bass, LJ | 1 |
| Harrell, ER | 1 |
| Harper, RA | 1 |
| Flaxman, BA | 1 |
| Chopra, DP | 1 |
1 review available for theophylline and Psoriasis
| Article | Year |
|---|---|
Role of cyclic AMP in the control of epidermal cell growth and differentiation.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Cell Differentiation; Cell Division; Cyclic AMP; DNA; Epine | 1973 |
3 trials available for theophylline and Psoriasis
| Article | Year |
|---|---|
Efficacy of 2 weeks' application of theophylline ointment in psoriasis vulgaris.
Topics: Adult; Double-Blind Method; Female; Humans; Male; Ointments; Psoriasis; Severity of Illness Index; S | 2005 |
[Trial treatment of psoriasis by intralesional injections of AMPc, 8-thio-dibutyryl AMPc and theophylline].
Topics: Administration, Topical; Bucladesine; Clinical Trials as Topic; Cyclic AMP; Female; Humans; Injectio | 1976 |
[Therapeutic value of theophylline in psoriasis].
Topics: Administration, Topical; Anti-Inflammatory Agents; Clinical Trials as Topic; Drug Therapy, Combinati | 1976 |
19 other studies available for theophylline and Psoriasis
| Article | Year |
|---|---|
Epinephrine-induced cyclic AMP accumulation in the psoriatic epidermis.
Topics: Adolescent; Adult; Aged; Cyclic AMP; Epidermis; Epinephrine; Female; Humans; In Vitro Techniques; Ma | 1981 |
Adenosine-induced alterations in the adenosine 3':5'-monophosphate levels in mammalian epidermis.
Topics: Adenosine; Animals; Animals, Newborn; Cyclic AMP; Dipyridamole; Humans; In Vitro Techniques; Male; M | 1980 |
Immunological aspects of psoriasis. VI. Impairment of isoprenaline and theophylline-induced inhibition of mitogen responsiveness.
Topics: Adult; Aged; Blood Cells; Cell Division; Concanavalin A; Depression, Chemical; Female; Histamine; Hu | 1984 |
[Effect of complamin and prodectin on microcirculation and lipid metabolism in psoriasis patients].
Topics: Adolescent; Adult; Carbamates; Conjunctiva; Female; Humans; Lipoproteins; Male; Microcirculation; Mi | 1983 |
[Function of the sympathetico-adrenal system in psoriasis during theophylline treatment].
Topics: Adolescent; Adrenal Glands; Adult; Catecholamines; Chronic Disease; Humans; Middle Aged; Psoriasis; | 1982 |
Influence of intercellular agents on proliferation and gene activity of cultured human skin epithelium cells (NCTC 2544).
Topics: Cell Differentiation; Cell Line; Cells, Cultured; Chromosomal Proteins, Non-Histone; DNA Replication | 1981 |
Beneficial effect of a combination of retinoids and long-acting theophylline in the treatment of psoriasis vulgaris.
Topics: Adult; Age of Onset; Child; Drug Therapy, Combination; Humans; Middle Aged; Psoriasis; Retinoids; Th | 1994 |
Neutrophil chemotaxis in psoriasis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Chemotaxis, Leukocyte; Child; Cyclic AMP; Cyclic GMP; | 1979 |
[Use of complamin in some dermatoses].
Topics: Adolescent; Adult; Aged; Arteritis; Drug Evaluation; Eczema; Erythema; Female; Humans; Lichen Planus | 1975 |
Imbalanced cyclic AMP-cyclic GMP levels in psoriasis.
Topics: Animals; Bucladesine; Cell Differentiation; Cell Division; Cells, Cultured; Cyclic AMP; Cyclic GMP; | 1975 |
On the lack of response to catecholamine stimulation by the adenyl cyclase system in psoriatic lesions.
Topics: Adenylyl Cyclases; Adult; Cyclic AMP; Epinephrine; Humans; In Vitro Techniques; Male; Propranolol; P | 1975 |
Leukocyte and lymphocyte cyclic AMP responses in atopic eczema.
Topics: Adolescent; Adult; Albuterol; Cyclic AMP; Eczema; Epinephrine; Humans; In Vitro Techniques; Isoprote | 1977 |
Cyclic AMP accumulation in psoriatic skin: differential responses to histamine, AMP, and einephrine by the uninvolved and involved epidermis.
Topics: Adenosine Monophosphate; Cyclic AMP; Drug Interactions; Epidermis; Epinephrine; Histamine; Humans; I | 1978 |
Trials with xanthine derivatives in systemic treatment of psoriasis.
Topics: Adolescent; Adult; Aged; Aminophylline; Child; Cyclic AMP; Cyclic GMP; Humans; Male; Middle Aged; Ph | 1979 |
[Immediate results of treatment of psoriasis with phosphodiesterase inhibitors].
Topics: Adolescent; Adult; Aged; Aminophylline; Child; Drug Evaluation; Female; Humans; Male; Middle Aged; P | 1979 |
Xanthines inhibit 3T3 fibroblast proliferation.
Topics: 3T3 Cells; Animals; Caffeine; Cell Division; Dyphylline; Mice; Psoriasis; Theophylline; Xanthines | 1991 |
Altered theophylline metabolism in patients with psoriasis.
Topics: Aged; Female; Humans; Male; Middle Aged; Psoriasis; Theophylline | 1990 |
Defects and deficiency of adenyl cyclase in psoriatic skin.
Topics: Adenine; Adenylyl Cyclases; Adult; Carbon Isotopes; Cyclic AMP; Epinephrine; Fluorides; Glucose; Hum | 1973 |
Mitotic response of normal and psoriatic keratinocytes in vitro to compounds known to affect intracellular cyclic AMP.
Topics: Bucladesine; Cells, Cultured; Cyclic AMP; Epinephrine; Epithelial Cells; Epithelium; Fluorides; Hist | 1974 |