emodin and Psoriasis
emodin has been researched along with Psoriasis in 3 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " By stimulating macrophages with imiquimod (IMQ) to model the inflammation in psoriasis, it was found that the anthraquinones significantly reduced IL-6, IL-23, and TNF." | 4.12 | A systematic comparison of the effect of topically applied anthraquinone aglycones to relieve psoriasiform lesion: The evaluation of percutaneous absorption and anti-inflammatory potency. ( Alalaiwe, A; Chuang, SY; Fang, JY; Huang, TH; Lin, CF; Nguyen, TMH; Wang, PW, 2022) |
| "Psoriasis is a chronic, immune-mediated inflammatory skin disorder." | 1.72 | Anti-Psoriatic Effect of ( Ahn, SH; Nguyen, LTH; Shin, HM; Yang, IJ, 2022) |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (100.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Lin, CF | 1 |
| Chuang, SY | 1 |
| Huang, TH | 1 |
| Nguyen, TMH | 1 |
| Wang, PW | 1 |
| Alalaiwe, A | 1 |
| Fang, JY | 1 |
| Xiao, D | 1 |
| Wang, J | 1 |
| Zhong, Y | 1 |
| Sun, H | 1 |
| Wang, M | 1 |
| Wang, X | 1 |
| Ding, Y | 1 |
| Li, Y | 1 |
| Wang, Y | 1 |
| Nguyen, LTH | 1 |
| Ahn, SH | 1 |
| Shin, HM | 1 |
| Yang, IJ | 1 |
Other Studies
3 other studies available for emodin and Psoriasis
| Article | Year |
|---|---|
A systematic comparison of the effect of topically applied anthraquinone aglycones to relieve psoriasiform lesion: The evaluation of percutaneous absorption and anti-inflammatory potency.
Topics: Administration, Topical; Animals; Anthraquinones; Anti-Inflammatory Agents; Cytokines; Disease Model | 2022 |
Study on HPLC Fingerprint, Network Pharmacology, and Antifungal Activity of Rumex japonicus Houtt.
Topics: Antifungal Agents; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Glucosides; | 2022 |
Anti-Psoriatic Effect of
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Emodin; Interleukin-17; Mice; Psoriasis; Rheum | 2022 |