mercaptoethanol has been researched along with Psoriasis in 4 studies
Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To evaluate the anti-psoriatic potential of 2-ME, psoriasis-like dermatitis was induced by topical application of imiquimod (IMQ) on the dorsal skin of C57BL/6 mice for seven consecutive days, followed by treatment of vehicle or 2-ME ointment from Day 4 on." | 8.12 | Inhibition of JAK1/STAT3 pathway by 2-methoxyestradiol ameliorates psoriatic features in vitro and in an imiquimod-induced psoriasis-like mouse model. ( Li, M; Liu, C; Liu, S; Lu, J; Tang, J; Zhou, X; Zhu, L, 2022) |
| " To evaluate the anti-psoriatic potential of 2-ME, psoriasis-like dermatitis was induced by topical application of imiquimod (IMQ) on the dorsal skin of C57BL/6 mice for seven consecutive days, followed by treatment of vehicle or 2-ME ointment from Day 4 on." | 4.12 | Inhibition of JAK1/STAT3 pathway by 2-methoxyestradiol ameliorates psoriatic features in vitro and in an imiquimod-induced psoriasis-like mouse model. ( Li, M; Liu, C; Liu, S; Lu, J; Tang, J; Zhou, X; Zhu, L, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tang, J | 1 |
| Liu, C | 1 |
| Liu, S | 1 |
| Zhou, X | 1 |
| Lu, J | 1 |
| Li, M | 1 |
| Zhu, L | 1 |
| Thaler, MP | 1 |
| Fukuyama, K | 1 |
| Inoue, N | 1 |
| Cram, DL | 1 |
| Epstein, WL | 1 |
| Volk, HD | 1 |
| Koyka, I | 1 |
| Goan, SR | 1 |
| Gruner, S | 1 |
| Fiebig, H | 1 |
| Sönnichsen, N | 1 |
| Diezel, W | 1 |
| Krogh, HK | 1 |
4 other studies available for mercaptoethanol and Psoriasis
| Article | Year |
|---|---|
Inhibition of JAK1/STAT3 pathway by 2-methoxyestradiol ameliorates psoriatic features in vitro and in an imiquimod-induced psoriasis-like mouse model.
Topics: 2-Methoxyestradiol; Animals; Cell Proliferation; Dermatitis; Disease Models, Animal; Endothelial Cel | 2022 |
Two tris urea mercaptoethanol extractable polypeptides found uniquely in scales of patients with psoriasis.
Topics: Humans; Immune Sera; Mercaptoethanol; Peptides; Psoriasis; Skin; Tromethamine; Urea | 1978 |
Serum-mediated inhibition of the interferon-gamma-induced HLA-DR expression on monocytes in patients with psoriasis.
Topics: Antigens, Surface; Cells, Cultured; HLA-D Antigens; HLA-DR Antigens; Humans; Indomethacin; Interfero | 1986 |
The occurrence of antibodies to stratum corneum in man.
Topics: Amniotic Fluid; Animals; Antibodies; Antigen-Antibody Reactions; Antigens; Complement System Protein | 1970 |