chloroquine has been researched along with Psoriasis in 37 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " PHA-stimulated T cells were additionally treated with psoriasis-provoking drugs (lithium, chloroquine, propranolol and ethanol) and the two immunosuppressive drugs cyclosporin A and FK 506." | 7.69 | Tyrosine phosphorylation in psoriatic T cells is modulated by drugs that induce or improve psoriasis. ( Goos, M; Mertins, K; Nussbaum, G; Ockenfels, HM; Schultewolter, T; Wagner, SN, 1995) |
| "Chloroquine is known to exacerbate psoriasis." | 7.68 | Chloroquine stimulates the mitogen-driven lymphocyte proliferation in patients with psoriasis. ( Morsches, B; Ockenfels, HM; Schopf, RE; Schultewolter, T, 1993) |
| "Two patients with psoriasis vulgaris who travelled to endemic malaria areas developed erythroderma and generalized psoriasis guttata 3-4 weeks after starting prophylactic antimalarial medication with chloroquine/proguanil." | 7.68 | [Exacerbation of psoriasis caused by malaria prophylaxis with chloroquine and proguanil]. ( Damstra, RJ; van Vloten, WA, 1991) |
| "We present a patient with psoriasis who developed exfoliative dermatitis with concomitant fever, malaise and liver enzyme elevations, two days after the introduction of the new calcium antagonist diltiazem." | 7.67 | Diltiazem-associated exfoliative dermatitis in a patient with psoriasis. ( Lavrijsen, AP; Van Dijke, C; Vermeer, BJ, 1986) |
| "To investigate whether lithium carbonate, propranolol or chloroquine aggravate psoriasis through influencing cytokines of the psoriatic cytokine network, HaCaT keratinocytes were stimulated with TNF-a after treatment with these drugs." | 3.74 | [Effects of drugs known to trigger psoriasis on HaCaT keratinocytes]. ( Cen, JP; Cheng, H; Jin, N; Lin, AH; Zhu, KJ, 2007) |
| " PHA-stimulated T cells were additionally treated with psoriasis-provoking drugs (lithium, chloroquine, propranolol and ethanol) and the two immunosuppressive drugs cyclosporin A and FK 506." | 3.69 | Tyrosine phosphorylation in psoriatic T cells is modulated by drugs that induce or improve psoriasis. ( Goos, M; Mertins, K; Nussbaum, G; Ockenfels, HM; Schultewolter, T; Wagner, SN, 1995) |
| "Chloroquine is known to exacerbate psoriasis." | 3.68 | Chloroquine stimulates the mitogen-driven lymphocyte proliferation in patients with psoriasis. ( Morsches, B; Ockenfels, HM; Schopf, RE; Schultewolter, T, 1993) |
| "The lysosomotropic drug chloroquine has been added to cultures containing peripheral blood mononuclear cells (PBMC) and allogeneic antigen-presenting cells obtained from the epidermis of normal human skin or from skin of patients with psoriasis." | 3.68 | Effects of chloroquine on antigen-presenting functions of epidermal cells from normal and psoriatic skin. ( Demidem, A; Grammer, SF; Streilein, JW; Taylor, JR, 1992) |
| "Two patients with psoriasis vulgaris who travelled to endemic malaria areas developed erythroderma and generalized psoriasis guttata 3-4 weeks after starting prophylactic antimalarial medication with chloroquine/proguanil." | 3.68 | [Exacerbation of psoriasis caused by malaria prophylaxis with chloroquine and proguanil]. ( Damstra, RJ; van Vloten, WA, 1991) |
| "We present a patient with psoriasis who developed exfoliative dermatitis with concomitant fever, malaise and liver enzyme elevations, two days after the introduction of the new calcium antagonist diltiazem." | 3.67 | Diltiazem-associated exfoliative dermatitis in a patient with psoriasis. ( Lavrijsen, AP; Van Dijke, C; Vermeer, BJ, 1986) |
| " The higher dosage of chloroquine caused no exacerbations." | 1.26 | Effect of antimalarial drugs on psoriasis. ( Kuflik, EG, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (81.08) | 18.7374 |
| 1990's | 6 (16.22) | 18.2507 |
| 2000's | 1 (2.70) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FISHER, S | 1 |
| VACHTENHEIM, J | 1 |
| SMID, V | 1 |
| KOSZTOLNYIK, J | 1 |
| TAKACS, B | 1 |
| SZATMARI, M | 1 |
| GAIZLER, G | 1 |
| BIELICKY, T | 2 |
| KIRSCHENBAUM, MB | 1 |
| WOJTKIEWICZ, J | 1 |
| LECEWICZ TORUN, B | 1 |
| EDDY, DD | 1 |
| ASCHHEIM, E | 1 |
| FARBER, EM | 3 |
| MARCHIONINI, A | 1 |
| MUELLER, E | 1 |
| SCHROEPL, F | 1 |
| ROTH, RJ | 1 |
| O'QUINN, SE | 1 |
| KENNEDY, CB | 1 |
| NAYLOR, LZ | 1 |
| HELLERSTROEM, S | 1 |
| KVICALOVA, E | 1 |
| WILLIAMS, DI | 1 |
| Cen, JP | 1 |
| Zhu, KJ | 1 |
| Jin, N | 1 |
| Lin, AH | 1 |
| Cheng, H | 1 |
| Kuflik, EG | 1 |
| Zbojanova, M | 1 |
| Vlcek, F | 1 |
| Olsen, TG | 1 |
| Schopf, RE | 1 |
| Ockenfels, HM | 2 |
| Schultewolter, T | 2 |
| Morsches, B | 1 |
| Nussbaum, G | 1 |
| Mertins, K | 1 |
| Wagner, SN | 1 |
| Goos, M | 1 |
| Frain-Bell, W | 1 |
| Vestey, JP | 1 |
| Savin, JA | 1 |
| Demidem, A | 1 |
| Taylor, JR | 1 |
| Grammer, SF | 1 |
| Streilein, JW | 1 |
| Damstra, RJ | 1 |
| van Vloten, WA | 1 |
| Katugampola, G | 1 |
| Katugampola, S | 1 |
| Lavrijsen, AP | 1 |
| Van Dijke, C | 1 |
| Vermeer, BJ | 1 |
| Mallett, R | 1 |
| Pye, R | 1 |
| Nicolas, JF | 1 |
| Mauduit, G | 1 |
| Haond, J | 1 |
| Chouvet, B | 1 |
| Thivolet, J | 1 |
| Stone, OJ | 2 |
| Huriez, C | 1 |
| Desmons, F | 1 |
| Gautier, G | 1 |
| Babaiants, RS | 1 |
| Shakhtmeĭster, II | 1 |
| Shelest, GV | 1 |
| Sharapova, GIa | 1 |
| Khamaganova, AV | 1 |
| Copeman, PW | 1 |
| Missmahl, HP | 1 |
| Baker, H | 1 |
| Lakos, T | 1 |
| Karasek, MA | 1 |
6 reviews available for chloroquine and Psoriasis
| Article | Year |
|---|---|
ADVANCES IN THE TREATMENT OF SKIN DISEASES.
Topics: Adrenal Cortex Hormones; Chloroquine; Drug Therapy; Electric Stimulation Therapy; Idoxuridine; Lupus | 1964 |
Dowling Oration 1978. What is that thing called light?
Topics: Adolescent; Adult; Aged; Carotenoids; Child; Child, Preschool; Chloroquine; Female; Furocoumarins; H | 1979 |
[Treatment of psoriasis].
Topics: Adrenocorticotropic Hormone; Aminopterin; Chloroquine; Dexamethasone; Diet Therapy; Flumethasone; Gl | 1972 |
Chloroquine.
Topics: Abnormalities, Drug-Induced; Animals; Ascorbic Acid; Child; Chloroquine; Enzymes; Eye Diseases; Fema | 1967 |
[Amyloidosis in chronic rheumatic diseases].
Topics: Adult; Aged; Amyloidosis; Arthritis, Rheumatoid; Biopsy; Chloroquine; Chronic Disease; Collagen Dise | 1968 |
Psoriasis--clinical features.
Topics: Acrodermatitis; Arthritis, Infectious; Arthritis, Reactive; Child; Child, Preschool; Chloroquine; Di | 1971 |
31 other studies available for chloroquine and Psoriasis
| Article | Year |
|---|---|
Psoriatic erythroderma, rheumatoid arthritis, and death, as a sequence to a drug reaction.
Topics: Arthritis; Arthritis, Rheumatoid; Chloroquine; Dermatitis, Exfoliative; Humans; Hypersensitivity; Me | 1961 |
[Treatment of psoriatic arthropathy with resochin].
Topics: Antimalarials; Arthritis, Psoriatic; Chloroquine; Humans; Joint Diseases; Psoriasis | 1961 |
[The use of chloroquine derivatives in the therapy of spondylarthritis ankylopoietica and arthropathia psoriatica].
Topics: Chloroquine; Humans; Joint Diseases; Psoriasis; Spondylitis; Spondylitis, Ankylosing | 1959 |
LIGHT-SENSITIVE PSORIASIS AND ANTIMALARIAL DRUGS.
Topics: Antimalarials; Chloroquine; Dermatitis, Phototoxic; Humans; Light; Photosensitivity Disorders; Psori | 1963 |
PSORIASIS FOLLOWING ADMINISTRATION OF ANTIMALARIAL DRUGS.
Topics: Antimalarials; Chloroquine; Humans; Primaquine; Psoriasis; Toxicology | 1963 |
[RESULTS OF RESOCHIN THERAPY OF CHRONIC LUPUS ERYTHEMATOSUS AND PSORIASIS].
Topics: Chloroquine; Lupus Erythematosus, Systemic; Psoriasis | 1963 |
EXPERIMENTAL ANALYSIS OF ISOMORPHIC (KOEBNER) RESPONSE IN PSORIASIS.
Topics: Chloroquine; Colchicine; Cold Temperature; Dermabrasion; Histology; Humans; Idoxuridine; Iontophores | 1964 |
[ON THE ETIOLOGY, PATHOGENESIS, PROPHYLAXIS AND THERAPY OF PSORIASIS].
Topics: Adrenal Cortex Hormones; Aminopterin; Capillaries; Chloroquine; Dermatitis, Exfoliative; Folic Acid; | 1963 |
CURRENT CONCEPTS IN THE DIAGNOSIS AND TREATMENT OF PSORIASIS.
Topics: Adrenal Cortex Hormones; Aminopterin; Antimalarials; Arthritis; Child; Chloroquine; Coal Tar; Diagno | 1964 |
PSORIASIS, ULTRAVIOLET LIGHT, AND CHLOROQUINE.
Topics: Biomedical Research; Chloroquine; Humans; Metabolism; Pharmacology; Psoriasis; Radiation Effects; Ul | 1964 |
[PSORIASIS AND ITS TREATMENT IN THE LIGHT OF A NEW EXPERIENCE].
Topics: Chloroquine; Fluocinolone Acetonide; Humans; Light; Psoriasis; Quinacrine | 1964 |
PHOTOSENSITIVE PSORIASIS.
Topics: Chloroquine; Dermatitis, Phototoxic; Drug Therapy; Humans; Photosensitivity Disorders; Psoriasis; Su | 1964 |
[Effects of drugs known to trigger psoriasis on HaCaT keratinocytes].
Topics: Adrenergic beta-Antagonists; Antimalarials; Cells, Cultured; Chloroquine; Humans; Interleukin-6; Int | 2007 |
Effect of antimalarial drugs on psoriasis.
Topics: Adult; Antimalarials; Chloroquine; Dermatitis, Exfoliative; Female; Humans; Malaria; Male; Middle Ag | 1980 |
[Delagil therapy of psoriatic arthritis].
Topics: Adult; Aged; Antimalarials; Arthritis; Chloroquine; Female; Humans; Male; Middle Aged; Psoriasis | 1980 |
Chloroquine and psoriasis.
Topics: Chloroquine; Humans; Male; Middle Aged; Psoriasis | 1981 |
Chloroquine stimulates the mitogen-driven lymphocyte proliferation in patients with psoriasis.
Topics: Adult; Aged; Aged, 80 and over; Cell Division; Cells, Cultured; Chloroquine; Female; Humans; Lymphoc | 1993 |
Tyrosine phosphorylation in psoriatic T cells is modulated by drugs that induce or improve psoriasis.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Cells, Cultured; Chloroquine; Cyclosporine; Ethanol; | 1995 |
Psoriasis worsened by antimalarial prophylaxis.
Topics: Antimalarials; Chloroquine; Humans; Malaria; Male; Middle Aged; Psoriasis | 1992 |
Effects of chloroquine on antigen-presenting functions of epidermal cells from normal and psoriatic skin.
Topics: Antigen-Presenting Cells; Chloroquine; Cyclosporine; Humans; Lymphotoxin-alpha; Psoriasis; Skin | 1992 |
[Exacerbation of psoriasis caused by malaria prophylaxis with chloroquine and proguanil].
Topics: Chloroquine; Humans; Malaria; Male; Middle Aged; Proguanil; Psoriasis | 1991 |
Chloroquine and psoriasis.
Topics: Chloroquine; Humans; Psoriasis; Retrospective Studies; Time Factors | 1990 |
Diltiazem-associated exfoliative dermatitis in a patient with psoriasis.
Topics: Aged; Chloroquine; Dermatitis, Exfoliative; Diltiazem; Female; Humans; Psoriasis | 1986 |
Risks and benefits of prophylactic antimalarial drugs.
Topics: Chloroquine; Humans; Male; Middle Aged; Psoriasis | 1989 |
[Severe psoriasis induced by chloroquine (nivaquine)].
Topics: Aged; Aged, 80 and over; Chloroquine; Dermatitis, Exfoliative; Drug Eruptions; Drug Interactions; Hu | 1988 |
Chloroquine, ground substance, aggravation of psoriasis.
Topics: Chloroquine; Humans; Psoriasis; Skin | 1985 |
[Complications with synthetic antimalarials].
Topics: Antimalarials; Asthenia; Central Nervous System Diseases; Chloroquine; Drug Eruptions; Eczema; Eye D | 1969 |
[Treatment of some dermatoses by the intradermal injections of a 10 percent solution of quingamine].
Topics: Adult; Chloroquine; Chronic Disease; Female; Humans; Injections, Intradermal; Keloid; Lupus Erythema | 1973 |
Effect of delagil in psoriasis, photodermatosis and discoid erythematodes.
Topics: Chloroquine; Humans; Lupus Erythematosus, Discoid; Photosensitivity Disorders; Psoriasis | 1968 |
Early cellular inflammation and neoplasia control.
Topics: Arsenic; Carcinogens; Chloroquine; Folliculitis; Infections; Inflammation; Neoplasms; Psoriasis; Ski | 1968 |
[Effect of chloroquine, primaquine and phenylhydrazine on the glutathione levels of erythrocytes in psoriasis].
Topics: Chloroquine; Erythrocytes; Glutathione; Humans; Phenylhydrazines; Primaquine; Psoriasis | 1966 |