5,10,15,20-tetrakis(4-methoxyphenyl)porphyrin profile

Cross-References

ID Source	ID
PubMed CID	135404412
CHEMBL ID	3883784
SCHEMBL ID	949511
MeSH ID	M0413241

Synonyms (32)

Synonym
nsc 241210
porphine, 5,10,15,20-tetrakis(p-methoxyphenyl)-
21h,23h-porphine, 5,10,15,20-tetrakis(4-methoxyphenyl)-
4-methoxy-1-[7,12,17-tris(4-methoxyphenyl)-21,22,23,24-tetraazapentacyclo[16.2.1.1<3,6>.1<8,11>.1<13,16>]tetracosa-1(21),2,4,6,8(23),9,11,13,15,17,19-undecaen-2-yl]benzene
(5z,10z,14z,19z)-5,10,15,20-tetrakis(4-methoxyphenyl)-21,23-dihydroporphyrin
dd-039
tetra(p-methoxyphenyl)porphyrin
22112-78-3
porphine,10,15,20-tetrakis(p-methoxyphenyl)-
nsc241210
nsc-241210
21h, 5,10,15,20-tetrakis(4-methoxyphenyl)-
5,10,15,20-tetrakis(4-methoxyphenyl)-21h,23h-porphine, dye content 95 %
AC-11777
5,10,15,20-tetrakis(4-methoxyphenyl)-21h,23h-porphine
T1360
5,10,15,20-tetrakis(4-methoxyphenyl)porphyrin
AKOS005493092
SCHEMBL949511
5,10,15,20-tetrakis(4-methoxyphenyl)porphyrin, 98%
mfcd00012072
meso-tera(4-methoxyphenyl)porphyrin
2,7,12,17-tetrakis(4-methoxyphenyl)-21,22,23,24-tetraazapentacyclo[16.2.1.1(3),?.1?,(1)(1).1(1)(3),(1)?]tetracosa-1,3,5,7,9,11(23),12,14,16,18(21),19-undecaene
AS-69307
CHEMBL3883784
AMY7172
CS-W009576
A878711
D95333
tetramethoxyphenyl porphyrin
YSWG692
5,10,15,20-tetrakis(4-methoxyphenyl)-21,23-dihydroporphyrin

Bioassays (3)

Assay ID	Title	Year	Journal	Article
AID1336590	Phototoxicity against human HaCaT cells assessed as cell viability at 1 uM after irradiation with light at 180 J/cm'2 for 30 mins by MTT assay	2017	Bioorganic & medicinal chemistry letters, 01-15, Volume: 27, Issue:2	Photodynamic effect of meso-(aryl)porphyrins and meso-(1-methyl-4-pyridinium)porphyrins on HaCaT keratinocytes.
AID1336589	Photostability of compound in aqueous media assessed as amount of soret band remaining after irradiation with white light at 100 mW/cm'2 for 30 mins by UV-spectrophotometric analysis	2017	Bioorganic & medicinal chemistry letters, 01-15, Volume: 27, Issue:2	Photodynamic effect of meso-(aryl)porphyrins and meso-(1-methyl-4-pyridinium)porphyrins on HaCaT keratinocytes.
AID1336591	Induction of singlet oxygen production assessed as amount of DPiBF remaining after irradiation with light at 9 mW/cm'2 for 30 mins by DPiBF photooxidation based spectrophotometric analysis (Rvb = 80%)	2017	Bioorganic & medicinal chemistry letters, 01-15, Volume: 27, Issue:2	Photodynamic effect of meso-(aryl)porphyrins and meso-(1-methyl-4-pyridinium)porphyrins on HaCaT keratinocytes.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (33.33)	29.6817
2010's	5 (55.56)	24.3611
2020's	1 (11.11)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	9 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
aminolevulinic acid Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.. 5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.	2.06	1	4-oxo monocarboxylic acid; amino acid zwitterion; delta-amino acid	antineoplastic agent; dermatologic drug; Escherichia coli metabolite; human metabolite; mouse metabolite; photosensitizing agent; plant metabolite; prodrug; Saccharomyces cerevisiae metabolite
tryptophan Tryptophan: An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.. tryptophan : An alpha-amino acid that is alanine bearing an indol-3-yl substituent at position 3.	2	1	erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid zwitterion; L-alpha-amino acid; proteinogenic amino acid; tryptophan zwitterion; tryptophan	antidepressant; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
luminol Luminol: 5-Amino-2,3-dihydro-1,4-phthalazinedione. Substance that emits light on oxidation. It is used in chemical determinations.	2.06	1
malondialdehyde Malondialdehyde: The dialdehyde of malonic acid.. malonaldehyde : A dialdehyde that is propane substituted by two oxo groups at the terminal carbon atoms respectively. A biomarker of oxidative damage to lipids caused by smoking, it exists in vivo mainly in the enol form.	2.06	1	dialdehyde	biomarker
palladium Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.. palladium : Chemical element (nickel group element atom) with atomic number 46.	2.07	1	metal allergen; nickel group element atom; platinum group metal atom
sodium selenite disodium selenite : An inorganic sodium salt composed of sodium and selenite ions in a 2:1 ratio.	2.05	1	inorganic sodium salt; selenite salt	nutraceutical
cobalt Cobalt: A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.. cobalt(1+) : A monovalent inorganic cation obtained from cobalt.. cobalt atom : A cobalt group element atom that has atomic number 27.	2.05	1	cobalt group element atom; metal allergen	micronutrient
hydroxyl radical Hydroxyl Radical: The univalent radical OH. Hydroxyl radical is a potent oxidizing agent.	2.25	1	oxygen hydride; oxygen radical; reactive oxygen species
zinc tetra(4-n-methylpyridyl)porphine [no description available]	2.06	1
tetraphenylporphine tetraphenylporphyrin: structure in first source	2.15	1
5-(4-aminophenyl)-10,15,20-triphenylporphyrin 5-(4-aminophenyl)-10,15,20-triphenylporphyrin: structure in first source	2.15	1
insulin [no description available]	2.15	1

Condition	Relationship Strength	Studies
Palmoplantaris Pustulosis [description not available]	2.15	1
Psoriasis A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.	2.15	1
Benign Neoplasms [description not available]	2.25	1
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	2.25	1
Carcinoma 256, Walker A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed)	2.47	2
Fibrosarcoma A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)	2.07	1
Breast Cancer [description not available]	2.02	1
Breast Neoplasms Tumors or cancer of the human BREAST.	2.02	1
Experimental Hepatoma [description not available]	2	1

5,10,15,20-tetrakis(4-methoxyphenyl)porphyrin

Cross-References

Synonyms (32)

Bioassays (3)

Research

Studies (9)

Study Types

5,10,15,20-tetrakis(4-methoxyphenyl)porphyrin

Cross-References

Synonyms (32)

Bioassays (3)

Research

Studies (9)

Study Types

Related Drugs (12)

Related Conditions (9)