2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Psoriasis in 2 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "TNF-α treatment enhanced inflammation and suppressed autophagy in HaCaT and NHEK cells, which were largely reversed by overexpression of lncRNA MEG3." | 1.62 | LncRNA MEG3 suppresses PI3K/AKT/mTOR signalling pathway to enhance autophagy and inhibit inflammation in TNF-α-treated keratinocytes and psoriatic mice. ( Jia, HY; Lv, SC; Tang, ZL; Xu, GW; Zhang, JF; Zhang, K, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, Y | 1 |
| Zhu, X | 1 |
| Li, Y | 1 |
| Dou, Y | 1 |
| Wang, J | 1 |
| Qi, R | 1 |
| Ma, L | 1 |
| Tang, ZL | 1 |
| Zhang, K | 1 |
| Lv, SC | 1 |
| Xu, GW | 1 |
| Zhang, JF | 1 |
| Jia, HY | 1 |
2 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Psoriasis
| Article | Year |
|---|---|
LY294002 ameliorates psoriatic skin inflammation in mice via blocking the Notch1/Hes1-PTEN/AKT/IL-17A feedback loop.
Topics: Animals; Disease Models, Animal; Feedback; Inflammation; Interleukin-17; Mice; Phosphatidylinositol | 2023 |
LncRNA MEG3 suppresses PI3K/AKT/mTOR signalling pathway to enhance autophagy and inhibit inflammation in TNF-α-treated keratinocytes and psoriatic mice.
Topics: Animals; Autophagy; Chromones; Female; HaCaT Cells; Humans; Inflammation; Keratinocytes; Mice, Inbre | 2021 |