hydrocortisone 21-butyrate: RN given for (11beta)-isomer: 6677-99-2; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 10365526 |
| SCHEMBL ID | 4696 |
| MeSH ID | M0102625 |
| Synonym |
|---|
| einecs 229-715-8 |
| hydrocortisone 21-butyrate |
| stero to |
| cortisol, 21-butyrate |
| ceneo |
| hb(sub 21) |
| pregn-4-en-3,20-dione, 11,17-dihydroxy-21-(1-oxobutoxy)-, (11-beta)- |
| isdinium |
| hydrocortisone-21-butyrate |
| AKOS016016022 |
| xx86t7rlsc , |
| unii-xx86t7rlsc |
| 6677-99-2 |
| SCHEMBL4696 |
| pregn-4-ene-3,20-dione, 11,17-dihydroxy-21-(1-oxobutoxy)-, (11.beta.)- |
| AS-58772 |
| hydrocortisone 21-butyrate; cortisol 21-butyrate; butyric acid, 21-ester with cortisol; (11beta)-11,17-dihydroxy-21-(1-oxobutoxy)-pregn-4-ene-3,20-dione |
| hydrocortison-21-butyrat |
| DTXSID00875538 |
| [2-[(8s,9s,10r,11s,13s,14s,17r)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] butanoate |
| [2-[(8s,9s,10r,11r,13s,14s,17r)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] butanoate |
| Excerpt | Reference | Relevance |
|---|---|---|
| " In the case of HBP, LD50 by oral administration was the highest, and followed by subcutaneous and intraperitoneal administration in mice and rats." | ( [Studies on toxicity of hydrocortisone 17-butyrate 21-propionate -1. Acute toxicity of hydrocortisone 17-butyrate 21-propionate and its analogues in mice, rats and dogs (author's transl)]. Abe, S; Nakane, S; Ohzeki, M; Sasajima, M; Tarumoto, Y; Tsutsui, Y, 1981) | 0.26 |
| Excerpt | Reference | Relevance |
|---|---|---|
| " Hydrocortisone was slowly absorbed and did not reach a steady-state absorption rate during the experimental period." | ( Absorption and metabolism of hydrocortisone 21-butyrate, 21-hemisuccinate and hydrocortisone by skin of the rabbit ear during single-pass perfusion. Bast, GE; Kampffmeyer, HG, 1994) | 0.58 |
| " No hydrolysis of permethrin was detected; the appearance rate of 3-phenoxybenzyl alcohol with 3-phenoxybenzoic acid corresponded to the absorption rate of the substrate impurities." | ( No effect of albumin on the dermal absorption rate of hydrocortisone 21-butyrate, permethrin or diflunisal in the isolated, single-pass perfused rabbit ear. Bast, GE; Kampffmeyer, HG, 1996) | 0.54 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (13.09) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||