Page last updated: 2024-10-25

danthron and Psoriasis

danthron has been researched along with Psoriasis in 9 studies

danthron: structure
chrysazin : A dihydroxyanthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 1 and 8.

Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

Research Excerpts

ExcerptRelevanceReference
"Danthrone was inactive."1.29Down-regulation of epidermal growth factor receptors by dithranol. ( Arenberger, P; Kemény, L; Michel, G; Ruzicka, T, 1993)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's3 (33.33)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Müller, K3
Prinz, H1
Gawlik, I1
Ziereis, K1
Huang, HS1
Reindl, H2
Breu, K2
Bedord, CJ1
Young, JM1
Wagner, BM1
Schaltegger, A1
Bloch, U1
Krebs, A1
Kemény, L2
Michel, G1
Arenberger, P2
Ruzicka, T2
Gross, E1
Taskinen, J1
Haarala, J1
Wartiovaara, E1
Halmekoski, J1
Wiegrebe, W1
Plumier, E1
Mayer, KK1
Runne, U1
Schultz-Amling, W1
Rosmarinowski, J1
Safar, GJ1
Kubka, KD1

Other Studies

9 other studies available for danthron and Psoriasis

ArticleYear
Simple analogues of anthralin: unusual specificity of structure and antiproliferative activity.
    Journal of medicinal chemistry, 1997, Nov-07, Volume: 40, Issue:23

    Topics: Administration, Topical; Animals; Anthralin; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non

1997
Heterocyclic substituted anthralin derivatives as inhibitors of keratinocyte growth and inducers of differentiation.
    Bioorganic & medicinal chemistry letters, 2001, Jan-08, Volume: 11, Issue:1

    Topics: Administration, Topical; Anthralin; Anti-Inflammatory Agents; Cell Differentiation; Cell Division; C

2001
Antipsoriatic anthrones with modulated redox properties. 5. Potent inhibition of human keratinocyte growth, induction of keratinocyte differentiation, and reduced membrane damage by novel 10-arylacetyl-1,8-dihydroxy-9(10H)-anthracenones.
    Journal of medicinal chemistry, 2001, Mar-01, Volume: 44, Issue:5

    Topics: Acetanilides; Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Cell Differentiation; Cell Divis

2001
Anthralin inhibition of mouse epidermal arachidonic acid lipoxygenase in vitro.
    The Journal of investigative dermatology, 1983, Volume: 81, Issue:6

    Topics: Animals; Anthracenes; Anthralin; Anthraquinones; Arachidonate Lipoxygenases; Arachidonic Acid; Arach

1983
On the stability of some antipsoriatic active anthralin (dithranol) derivatives.
    Dermatologica, 1982, Volume: 165, Issue:4

    Topics: Anthracenes; Anthralin; Anthraquinones; Chemical Phenomena; Chemistry; Chromatography, High Pressure

1982
Down-regulation of epidermal growth factor receptors by dithranol.
    Acta dermato-venereologica, 1993, Volume: 73, Issue:1

    Topics: Anthralin; Anthraquinones; Cell Line; Dose-Response Relationship, Drug; Epidermis; ErbB Receptors; H

1993
Dithranol-induced down-regulation of 12(S)-hydroxyeicosatetraenoic acid [12(S)-HETE] receptors in a human epidermal cell line.
    Archives of dermatological research, 1991, Volume: 283, Issue:5

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Anthralin; Anthraquinones; Cell Line; Down-Regulation; E

1991
Oxidation of antipsoriatic 10-acyldithranol derivatives and dithranol to 1,8-dihydroxyanthraquinone.
    Archiv der Pharmazie, 1988, Volume: 321, Issue:2

    Topics: Anthralin; Anthraquinones; Chemical Phenomena; Chemistry; Magnetic Resonance Spectroscopy; Oxidation

1988
Experimental contribution to the dithranol-brown problem.
    Archives of dermatological research, 1985, Volume: 277, Issue:2

    Topics: Anthracenes; Anthralin; Anthraquinones; Hot Temperature; Humans; Mass Spectrometry; Psoriasis; Skin

1985