Assay ID | Title | Year | Journal | Article |
AID54115 | Compound was evaluated for the binding parameter by determining the number of nucleotides occluded by a bound angelicin (n) | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID1357671 | Genotoxicity in Salmonella typhimurium TA100 assessed as revertant colonies at 1 uL/plate in presence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID1357658 | Genotoxicity in Salmonella typhimurium TA98 assessed as revertant colonies at 10 uL/plate in absence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID16264 | Percentage of clearance of psoriatic lesions by 8-methoxypsoralen (8-MOP) for comparison at dose of 10 J/cm e2 ultraviolet-A radiation | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID89071 | Erythema induction by 8-methoxypsoralen (8-MOP) for comparison at dose of 4 J/cm e2 ultraviolet-A radiation in female patient; +++=very strong | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID619965 | Inhibition of NF-KB p50 subunit/DNA interaction after 20 mins by EMSA | 2011 | European journal of medicinal chemistry, Oct, Volume: 46, Issue:10
| Development of a novel furocoumarin derivative inhibiting NF-κB dependent biological functions: design, synthesis and biological effects. |
AID88890 | Number of treatments at dose of 10 J/cm e2 ultraviolet-A radiation | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID88892 | Number of treatments at dose of 6 J/cm e2 ultraviolet-A radiation | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID89080 | Erythema induction by the compound at dose of 8 J/cm e2 ultraviolet-A radiation in female patient; - = absent | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID1357654 | Induction of damage in salmon testes DNA at 100 uM in presence of 2.5 to 7.5 J/cm2 UVA irradiation by ethidium bromide dye-based agarose gel electrophoresis analysis | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID90073 | Pigmentation capacity of 8-methoxypsoralen (8-MOP) for comparison at dose of 6 J/cm e2 ultraviolet-A radiation in female patient; + = moderate | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID90078 | Pigmentation capacity at dose of 10 J/cm e2 ultraviolet-A radiation in female patient; ++=strong | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID88893 | Number of treatments at dose of 8 J/cm e2 ultraviolet-A radiation | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID16271 | Percentage of clearance of psoriatic lesions by the compound at dose of 8 J/cm e2 ultraviolet-A radiation | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID1357674 | Genotoxicity in Salmonella typhimurium TA100 assessed as revertant colonies at 50 uL/plate in presence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID89078 | Erythema induction by the compound at dose of 4 J/cm e2 ultraviolet-A radiation in female patient; - = absent | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID90079 | Pigmentation capacity at dose of 6 J/cm e2 ultraviolet-A radiation in female patient; + = moderate | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID89070 | Erythema induction by 8-methoxypsoralen (8-MOP) for comparison at dose of 10 J/cm e2 ultraviolet-A radiation in female patient; +++=very strong | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID89073 | Erythema induction by 8-methoxypsoralen (8-MOP) for comparison at dose of 6 J/cm e2 ultraviolet-A radiation in female patient; +++ = very strong | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID1357668 | Genotoxicity in Salmonella typhimurium TA100 assessed as revertant colonies at 10 uL/plate in absence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID16270 | Percentage of clearance of psoriatic lesions by the compound at dose of 6 J/cm e2 ultraviolet-A radiation | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID1357669 | Genotoxicity in Salmonella typhimurium TA100 assessed as revertant colonies at 50 uL/plate in absence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID1357665 | Genotoxicity in Salmonella typhimurium TA98 assessed as revertant colonies at 100 uL/plate in presence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID1357667 | Genotoxicity in Salmonella typhimurium TA100 assessed as revertant colonies at 5 uL/plate in absence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID90083 | Pigmentation capacity at dose of 9 J/cm e2 ultraviolet-A radiation in female patient; +=moderate | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID89072 | Erythema induction by 8-methoxypsoralen (8-MOP) for comparison at dose of 6 J/cm e2 ultraviolet-A radiation in female patient; ++ = strong | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID16268 | Percentage of clearance of psoriatic lesions by the compound at dose of 10 J/cm e2 ultraviolet-A radiation | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID91202 | Number of treatments at dose of 6 J/cm e2 ultraviolet-A radiation | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID1357663 | Genotoxicity in Salmonella typhimurium TA98 assessed as revertant colonies at 10 uL/plate in presence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID16265 | Percentage of clearance of psoriatic lesions by 8-methoxypsoralen (8-MOP) for comparison at dose of 6 J/cm e2 ultraviolet-A radiation | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID16266 | Percentage of clearance of psoriatic lesions by 8-methoxypsoralen (8-MOP) for comparison at dose of 8 J/cm e2 ultraviolet-A radiation | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID90071 | Pigmentation capacity of 8-methoxypsoralen (8-MOP) for comparison at dose of 10 J/cm e2 ultraviolet-A radiation in female patient; +=moderate | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID1357660 | Genotoxicity in Salmonella typhimurium TA98 assessed as revertant colonies at 100 uL/plate in absence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID89074 | Erythema induction by 8-methoxypsoralen (8-MOP) for comparison at dose of 8 J/cm e2 ultraviolet-A radiation in female patient, +=moderate | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID89077 | Erythema induction by the compound at dose of 10 J/cm e2 ultraviolet-A radiation in female patient; - = absent | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID90074 | Pigmentation capacity of 8-methoxypsoralen (8-MOP) for comparison at dose of 6 J/cm e2 ultraviolet-A radiation in female patient; ++ = strong | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID54807 | Compound was evaluated for the binding parameter by determining rate constant | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID54116 | Compound was evaluated for the frequency of the binding site that is the number of molecules bound to every nucleotide (1/n) | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID1357656 | Genotoxicity in Salmonella typhimurium TA98 assessed as revertant colonies at 5 uL/plate in absence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID16269 | Percentage of clearance of psoriatic lesions by the compound at dose of 4 J/cm e2 ultraviolet-A radiation | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID1357662 | Genotoxicity in Salmonella typhimurium TA98 assessed as revertant colonies at 5 uL/plate in presence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID1357670 | Genotoxicity in Salmonella typhimurium TA100 assessed as revertant colonies at 100 uL/plate in absence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID1357659 | Genotoxicity in Salmonella typhimurium TA98 assessed as revertant colonies at 50 uL/plate in absence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID88891 | Number of treatments at dose of 4 J/cm e2 ultraviolet-A radiation (female patient) | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID130473 | Compound was evaluated for 50% inhibition of DNA synthesis in Ehrlich ascites tumor cells by irradiation (365 nM) at 1.9 x 10e -5M incubated with [3H]thymidine at 37 degree C (p 0.05) | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID90072 | Pigmentation capacity of 8-methoxypsoralen (8-MOP) for comparison at dose of 4 J/cm e2 ultraviolet-A radiation in female patient; - = absent | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID1357701 | Inhibition of NF-kappaB (unknown origin) assessed as decrease in NF-kappaB/DNA interaction at 12.5 to 100 uM using 32P-labeled target NF-kappaB double-stranded oligonucleotide after 30 mins by EMSA | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID1357666 | Genotoxicity in Salmonella typhimurium TA100 assessed as revertant colonies at 1 uL/plate in absence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID1357657 | Genotoxicity in Salmonella typhimurium TA98 assessed as revertant colonies at 1 uL/plate in absence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID1357672 | Genotoxicity in Salmonella typhimurium TA100 assessed as revertant colonies at 5 uL/plate in presence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID1357675 | Genotoxicity in Salmonella typhimurium TA100 assessed as revertant colonies at 100 uL/plate in presence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID89079 | Erythema induction by the compound at dose of 6 J/cm e2 ultraviolet-A radiation in female patient; - = absent | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID1357673 | Genotoxicity in Salmonella typhimurium TA100 assessed as revertant colonies at 10 uL/plate in presence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID54459 | Compound was evaluated for the association constant to an isolated site of DNA | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID1357661 | Genotoxicity in Salmonella typhimurium TA98 assessed as revertant colonies at 1 uL/plate in presence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID90080 | Pigmentation capacity at dose of 8 J/cm e2 ultraviolet-A radiation in female patient; +++=very strong | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID90075 | Pigmentation capacity of 8-methoxypsoralen (8-MOP) for comparison at dose of 8 J/cm e2 ultraviolet-A radiation in female patient; +=moderate | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| 6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis. |
AID1357664 | Genotoxicity in Salmonella typhimurium TA98 assessed as revertant colonies at 50 uL/plate in presence of Sprague-Dawley rat S9 metabolic activation after 72 hrs by Ames test (Rvb = 1 No_unit) | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
AID1357702 | Induction of damage in salmon testes DNA at 100 uM in absence of 2.5 to 7.5 J/cm2 UVA irradiation by ethidium bromide dye-based agarose gel electrophoresis analysis | 2018 | European journal of medicinal chemistry, May-10, Volume: 151 | Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |