tyrphostin a23 has been researched along with Psoriasis in 2 studies
tyrphostin A23: inhibits EGF-stimulated thymidine incorporation as well as EGF-stimulated receptor autophosphorylation & tyrosine phosphorylation & cell proliferation; structure given in first source
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishizaki, M | 1 |
| Muromoto, R | 1 |
| Akimoto, T | 1 |
| Sekine, Y | 1 |
| Kon, S | 1 |
| Diwan, M | 1 |
| Maeda, H | 1 |
| Togi, S | 1 |
| Shimoda, K | 1 |
| Oritani, K | 1 |
| Matsuda, T | 1 |
| Ben-Bassat, H | 1 |
| Vardi, DV | 1 |
| Gazit, A | 1 |
| Klaus, SN | 1 |
| Chaouat, M | 1 |
| Hartzstark, Z | 1 |
| Levitzki, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Randomized, Double-blind, Placebo-controlled, Two-arm Study to Evaluate the Safety and Efficacy of Erlotinib in the Treatment of Moderate to Severe Psoriasis[NCT01006096] | Phase 2 | 0 participants (Actual) | Interventional | Withdrawn (stopped due to IND not obtained) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for tyrphostin a23 and Psoriasis
| Article | Year |
|---|---|
Tyk2 is a therapeutic target for psoriasis-like skin inflammation.
Topics: Animals; Blotting, Western; Calgranulin A; Cell Line; Cytokines; Defensins; Enzyme Inhibitors; Gene | 2014 |
Tyrphostins suppress the growth of psoriatic keratinocytes.
Topics: Benzylidene Compounds; Catechols; Cells, Cultured; Dermatologic Agents; ErbB Receptors; Female; Huma | 1995 |