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dehydroepiandrosterone and Psoriasis

dehydroepiandrosterone has been researched along with Psoriasis in 35 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

Research Excerpts

ExcerptRelevanceReference
"In patients with psoriasis in extra- and intracellular deficiency of dehydroepiandrosterone can be demonstrated which leads to an activation of the pentose-phosphate cycle."8.76[Dehydroepiandrosterone deficiency in psoriasis. Hypothesis on the etiopathogenesis of this disease]. ( Benes, P; Holzmann, H; Morsches, B, 1980)
"In patients with psoriasis in extra- and intracellular deficiency of dehydroepiandrosterone can be demonstrated which leads to an activation of the pentose-phosphate cycle."4.76[Dehydroepiandrosterone deficiency in psoriasis. Hypothesis on the etiopathogenesis of this disease]. ( Benes, P; Holzmann, H; Morsches, B, 1980)
"Psoriasis is a clinical conundrum that affects an estimated 1-3% of the world's population."1.33Steroid sulfatase inhibitors as novel additions to the antipsoriatic armamentarium. ( Namazi, MR, 2005)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199034 (97.14)18.7374
1990's0 (0.00)18.2507
2000's1 (2.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MALINA, L1
SONKA, J1
GREGOROVA, I1
MAGNUSSON, B1
JENSEN, CC1
Namazi, MR1
Holzmann, H26
Benes, P6
Morsches, B24
Matthaei, D1
Stöhr, L1
Henrich, B1
Schwarz, W1
Schell, H1
Hornstein, OP1
Hoffmann, G12
Schwarz, P1
Oertel, GW19
Fränz, J2
Goerz, G1
Luger, A1
Schopf, RE1
Müller, FJ1
Gebhardt, R2
Menzel, P4
Bregenzer, M2
Krapp, R6
Hoede, N4
Döhler, U1
Degenhardt, KH1
Beyer, J1
Wenzel, D1
Dennebaum, R1
Wenzel, F1
Hoffmann-Trefz, G1
Carter, ME1
James, VH1
Schirazi, M1

Reviews

4 reviews available for dehydroepiandrosterone and Psoriasis

ArticleYear
[Dehydroepiandrosterone deficiency in psoriasis. Hypothesis on the etiopathogenesis of this disease].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1980, Volume: 31, Issue:2

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstenediols; Dehydroepiandrosterone; Etiocholanolone; Glucosep

1980
[Psoriasis: A general disease? Can psoriasis be explained biochemically?].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1977, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Chemical Phenomena; Chemistry; Child; Child, Preschool; Cyclic AMP; Deficiency Di

1977
[Can psoriasis be classified as a DHEA deficiency syndrome?].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1971, Nov-15, Volume: 46, Issue:22

    Topics: Deficiency Diseases; Dehydroepiandrosterone; DNA; Female; Folic Acid; Glucosephosphate Dehydrogenase

1971
[Current views on the psoriasis problem].
    Hippokrates, 1972, Volume: 43, Issue:1

    Topics: Amyloidosis; Arthritis; Celiac Disease; Cholesterol; Dehydroepiandrosterone; Diabetes Complications;

1972

Trials

1 trial available for dehydroepiandrosterone and Psoriasis

ArticleYear
[Therapy of psoriasis using dehydroepiandrosterone-enanthate].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1972, Feb-01, Volume: 47, Issue:3

    Topics: Administration, Oral; Androstanes; Clinical Trials as Topic; Dehydroepiandrosterone; Female; Glucose

1972

Other Studies

30 other studies available for dehydroepiandrosterone and Psoriasis

ArticleYear
[THE URINARY EXCRETION OF DEHYDROEPIANDROSTERONE IN PATIENTS WITH PSORIASIS].
    Dermatologische Wochenschrift, 1964, Nov-14, Volume: 150

    Topics: Body Fluids; Dehydroepiandrosterone; Humans; Psoriasis; Urine

1964
Urinary neutral 17-ketosteroids in psoriasis; with special reference to the dehydroisoandrosterone and closely related steroids and excretory changes during fever- and ACTH-therapy.
    Acta dermato-venereologica, 1952, Volume: 32, Issue:2

    Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Dehydroepiandrosterone; Fever; Hydrogen-Ion Concentrat

1952
Steroid sulfatase inhibitors as novel additions to the antipsoriatic armamentarium.
    Medical science monitor : international medical journal of experimental and clinical research, 2005, Volume: 11, Issue:3

    Topics: Animals; Calcitriol; Cytokines; Dehydroepiandrosterone; Dermatologic Agents; Drug Interactions; Enzy

2005
[Psoriasis and haemodialysis: changes in plasma hormone concentration as a possible therapeutic mechanism (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1981, Sep-25, Volume: 106, Issue:39

    Topics: Dehydroepiandrosterone; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Pso

1981
[Penetration kinetics of dehydroepiandrosterone through the erythrocyte membrane (author's transl)].
    Archives of dermatological research, 1981, Volume: 270, Issue:1

    Topics: Adult; Dehydroepiandrosterone; Erythrocyte Membrane; Erythrocytes; Humans; Kinetics; Male; Middle Ag

1981
Testosterone serum levels in male psoriatics.
    Archives of dermatological research, 1981, Volume: 270, Issue:3

    Topics: Circadian Rhythm; Dehydroepiandrosterone; Humans; Male; Middle Aged; Psoriasis; Radioimmunoassay; Te

1981
[Family studies for detection of latent psoriatics by assay of alterations in steroid metabolism (author's transl)].
    Archiv fur dermatologische Forschung, 1975, Volume: 252, Issue:2

    Topics: Androstenediols; Cell Membrane Permeability; Dehydroepiandrosterone; Erythrocytes; Humans; Oxidation

1975
[Radioimmunoassay of dehydroepiandrosterone and 5-androstene-3-beta, 17-beta-diol in the plasma of psoriatics and controls].
    Archives of dermatological research, 1979, Volume: 266, Issue:2

    Topics: Adult; Aged; Androstenediols; Dehydroepiandrosterone; Female; Humans; Male; Middle Aged; Psoriasis;

1979
[Newer aspects of psoriasis therapy].
    Wiener medizinische Wochenschrift (1946), 1977, Dec-30, Volume: 127, Issue:24

    Topics: Cortisone; Cyclic AMP; Dehydroepiandrosterone; Heliotherapy; Humans; Immunity; Methotrexate; Ointmen

1977
Augmented glucose-6-phosphate dehydrogenase activity and normal penetration and metabolism of dehydroepiandrosterone in mononuclear leukocytes in psoriasis.
    Archives of dermatological research, 1986, Volume: 278, Issue:5

    Topics: Adult; Biological Transport; Dehydroepiandrosterone; Female; Glucosephosphate Dehydrogenase; Humans;

1986
[Studies on the plasma DHEA content of psoriasis patients].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1970, Aug-15, Volume: 45, Issue:16

    Topics: Adolescent; Adult; Child; Child, Preschool; Dehydroepiandrosterone; Erythrocytes; Female; Glucosepho

1970
[Steroids and the skin. VI. Urinary excretion of C19-steroids in psoriatics].
    Archiv fur dermatologische Forschung, 1971, Volume: 240, Issue:2

    Topics: Adolescent; Adult; Aged; Androstanes; Androsterone; Dehydroepiandrosterone; Etiocholanolone; Female;

1971
[C19-steroids in psoriasis].
    Acta endocrinologica. Supplementum, 1971, Volume: 152

    Topics: Dehydroepiandrosterone; Densitometry; Erythrocytes; Female; Glucosephosphate Dehydrogenase; Humans;

1971
[Steroids and skin. V. Plasma dehydroepiandrosterone and erythrocyte glucose-6-phosphate dehydrogenase activity in psoriatic patients before and after the administration of dehydroepiandrosterone sulfate].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1971, Volume: 9, Issue:1

    Topics: Dehydroepiandrosterone; Female; Glucosephosphate Dehydrogenase; Humans; Male; Psoriasis; Skin

1971
[Steroids and skin. IX. On the metabolism of 7 - 3 H-DHEA sulfate in psoriasis].
    Steroidologia, 1971, Volume: 2, Issue:3

    Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Androstanes; Chromatography, Thin Layer; Dehydroepiand

1971
[New data on psoriasis research].
    Deutsches medizinisches Journal, 1972, Feb-10, Volume: 23, Issue:2

    Topics: Dehydroepiandrosterone; Glucosephosphate Dehydrogenase; Humans; Pentosephosphates; Psoriasis

1972
[Steroids and the skin. 8. In vitro experiments with 7 - 3 H-dehydroepiandrosterone and its sulfoconjugates on intact erythrocytes in psoriasis vulgaris].
    Archiv fur dermatologische Forschung, 1972, Volume: 243, Issue:1

    Topics: Adult; Aged; Androstanes; Cell Membrane Permeability; Dehydroepiandrosterone; Erythrocytes; Female;

1972
[Effects of steroids on glucose-6-phosphate dehydrogenase and lipid metabolism].
    Zeitschrift fur Ernahrungswissenschaft. Journal of nutritional sciences. Supplementa, 1972, Volume: 12

    Topics: Adult; Androstanes; Androsterone; Blood Protein Disorders; Dehydroepiandrosterone; Female; Glucoseph

1972
[Effect of dehydroepiandrosterone on the mitosis in lymphocyte cultures].
    Deutsche medizinische Wochenschrift (1946), 1972, Oct-13, Volume: 97, Issue:41

    Topics: Cells, Cultured; Dehydroepiandrosterone; Humans; In Vitro Techniques; Lymphocytes; Mitosis; Psoriasi

1972
[Hyperinsulinism and limited glucose-tolerance in psoriasis].
    Archiv fur dermatologische Forschung, 1972, Volume: 245, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Biological Transport; Blood Glucose; Dehydroepiandrosterone

1972
Steroids and skin. XI. C 19 -steroids in skin eluates from psoriatics.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1972, Volume: 4, Issue:5

    Topics: 17-Ketosteroids; Adolescent; Adult; Androstenes; Androsterone; Dehydroepiandrosterone; Etiocholanolo

1972
[Recent findings on steroid metabolism in psoriasis].
    Archiv fur dermatologische Forschung, 1972, Volume: 244

    Topics: Androstenes; Dehydroepiandrosterone; Erythrocytes; Glucosephosphate Dehydrogenase; Humans; Pentoseph

1972
[Metabolism of dehydroepiandrosterone lauryl sulfate in psoriasis].
    Steroids and lipids research, 1972, Volume: 3, Issue:4

    Topics: 17-Ketosteroids; Androstenes; Androsterone; Chromatography, Thin Layer; Dehydroepiandrosterone; Fatt

1972
[Organ findings in psoriasis].
    Deutsche medizinische Wochenschrift (1946), 1973, Aug-11, Volume: 98, Issue:33

    Topics: Dehydroepiandrosterone; Erythrocytes; Female; Gout; Humans; Intestinal Diseases; Joint Diseases; Liv

1973
[Therapy of psoriasis with dehydroepiandrosterone-enanthate. II. Intramuscular depot application of 300 mg weekly (author's transl)].
    Archiv fur dermatologische Forschung, 1973, Volume: 247, Issue:1

    Topics: Androstenols; Dehydroepiandrosterone; Delayed-Action Preparations; Dose-Response Relationship, Drug;

1973
[The activity of 17 beta-hydroxysteroid-oxidoreductase in erythrocytes of psoriatics (author's transl)].
    Archiv fur dermatologische Forschung, 1974, Volume: 250, Issue:3

    Topics: Androstenediols; Androsterone; Dehydroepiandrosterone; Enzyme Activation; Erythrocytes; Female; Huma

1974
Comparison of effects of corticotrophin and corticosteroids on pituitary-adrenal function.
    Annals of the rheumatic diseases, 1971, Volume: 30, Issue:1

    Topics: 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Androstanes; Arthritis; A

1971
[Therapy of psoriasis using dehydroepiandrosterone-sulfate].
    Arztliche Forschung, 1971, Nov-10, Volume: 25, Issue:11

    Topics: Administration, Oral; Androstenols; Dehydroepiandrosterone; Erythrocytes; Female; Glucose-6-Phosphat

1971
Exogenous and endogenous provocation of psoriasis. A contribution to the Koebner phenomenon.
    Archiv fur dermatologische Forschung, 1974, Volume: 249, Issue:1

    Topics: Adolescent; Adult; Child; Cyclic AMP; Dehydroepiandrosterone; Female; Foodborne Diseases; Humans; In

1974
Interaction between dehydroepiandrosterone, cyclic adenosine-3',5'-monophosphate and glucose-6-phosphate-dehydrogenase in normal and diseased subjects.
    Experientia, 1974, Aug-15, Volume: 30, Issue:8

    Topics: Adult; Cyclic AMP; Dehydroepiandrosterone; Female; Glucosephosphate Dehydrogenase; Humans; Hyperlipi

1974