Page last updated: 2024-10-17

lactic acid and Psoriasis

lactic acid has been researched along with Psoriasis in 16 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

Research Excerpts

ExcerptRelevanceReference
"Scalp psoriasis is a common life-altering skin condition causing a great deal of distress."6.76Salicylic Acid 6% in an ammonium lactate emollient foam vehicle in the treatment of mild-to-moderate scalp psoriasis. ( Kircik, L, 2011)
"Psoriasis is an immune-mediated skin disorder, which is triggered by the aberrant activation of dendritic cells in skin."5.46Enhanced topical penetration, system exposure and anti-psoriasis activity of two particle-sized, curcumin-loaded PLGA nanoparticles in hydrogel. ( Chen, X; Cun, D; Liu, Z; Sun, L; Tong, HHY; Wang, L; Wang, R; Yan, R; Zheng, Y, 2017)
"A double-blind, single-site, split-face clinical study was organized and carried out in order to evaluate the efficacy, tolerability, and safety of a glycolic acid containing scalp lotion in conjunction with a betamethasone (as the 17-valerate) scalp application against conditions of psoriasis."5.09Double-blind clinical study reveals synergistic action between alpha-hydroxy acid and betamethasone lotions towards topical treatment of scalp psoriasis. ( Ioannides, D; Kostarelos, K; Lefaki, I; Minas, A; Teknetzis, A, 2000)
"Scalp psoriasis is a common life-altering skin condition causing a great deal of distress."2.76Salicylic Acid 6% in an ammonium lactate emollient foam vehicle in the treatment of mild-to-moderate scalp psoriasis. ( Kircik, L, 2011)
"Psoriasis is a chronic, inflammatory skin disease."1.62Abnormal composition of microbiota in the gut and skin of imiquimod-treated mice. ( Chang, L; Fujita, Y; Hashimoto, K; Hashimoto, Y; Ishima, T; Matsue, H; Shinno-Hashimoto, H; Wei, Y, 2021)
"Psoriasis is an immune-mediated skin disorder, which is triggered by the aberrant activation of dendritic cells in skin."1.46Enhanced topical penetration, system exposure and anti-psoriasis activity of two particle-sized, curcumin-loaded PLGA nanoparticles in hydrogel. ( Chen, X; Cun, D; Liu, Z; Sun, L; Tong, HHY; Wang, L; Wang, R; Yan, R; Zheng, Y, 2017)
" Conventional dosage forms like creams and ointments are commonly prefered for the therapy."1.37Microparticulate based topical delivery system of clobetasol propionate. ( Badıllı, U; Sen, T; Tarımcı, N, 2011)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199010 (62.50)18.7374
1990's1 (6.25)18.2507
2000's1 (6.25)29.6817
2010's3 (18.75)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Shinno-Hashimoto, H1
Hashimoto, Y1
Wei, Y1
Chang, L1
Fujita, Y1
Ishima, T1
Matsue, H1
Hashimoto, K1
Sun, L1
Liu, Z1
Wang, L1
Cun, D1
Tong, HHY1
Yan, R1
Chen, X1
Wang, R1
Zheng, Y1
Kircik, L1
Badıllı, U1
Sen, T1
Tarımcı, N1
STEFL, J1
ADAM, A1
GULDEN, K1
DIETZ, O1
KLEINE-NATROP, HE1
RICHTER, G1
MATHUS-GIELEN, D1
JIJAKLI-SOMVILLE, J1
DINDAL, A1
LAPIERE, M1
BRAUN-FALCO, O1
LEBENGLIK, M1
KAMINSKY, A1
Fisher, AA1
Kostarelos, K1
Teknetzis, A1
Lefaki, I1
Ioannides, D1
Minas, A1
Baden, HP1
Yoshida, Y1
Katoh, Y1
Shionoiri, H1
Ishii, M1

Trials

2 trials available for lactic acid and Psoriasis

ArticleYear
Salicylic Acid 6% in an ammonium lactate emollient foam vehicle in the treatment of mild-to-moderate scalp psoriasis.
    Journal of drugs in dermatology : JDD, 2011, Volume: 10, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Emollients; Female; Humans; Keratolytic Agents; Lactic Acid;

2011
Double-blind clinical study reveals synergistic action between alpha-hydroxy acid and betamethasone lotions towards topical treatment of scalp psoriasis.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2000, Volume: 14, Issue:1

    Topics: Administration, Topical; Anti-Inflammatory Agents; Betamethasone Valerate; Dosage Forms; Double-Blin

2000

Other Studies

14 other studies available for lactic acid and Psoriasis

ArticleYear
Abnormal composition of microbiota in the gut and skin of imiquimod-treated mice.
    Scientific reports, 2021, 05-28, Volume: 11, Issue:1

    Topics: Animals; Dermatitis; Disease Models, Animal; Female; Gastrointestinal Microbiome; Imiquimod; Lactic

2021
Enhanced topical penetration, system exposure and anti-psoriasis activity of two particle-sized, curcumin-loaded PLGA nanoparticles in hydrogel.
    Journal of controlled release : official journal of the Controlled Release Society, 2017, 05-28, Volume: 254

    Topics: Administration, Topical; Animals; Anti-Infective Agents, Local; Apoptosis; Cell Line; Chemistry, Pha

2017
Microparticulate based topical delivery system of clobetasol propionate.
    AAPS PharmSciTech, 2011, Volume: 12, Issue:3

    Topics: Administration, Topical; Anti-Inflammatory Agents; Clobetasol; Delayed-Action Preparations; Excipien

2011
[Treatment of psoriasis].
    Medizinische Klinik, 1957, Nov-08, Volume: 52, Issue:45

    Topics: Humans; Lactic Acid; Psoriasis

1957
[Lactic acid therapy of psoriasis].
    Hippokrates, 1961, Mar-15, Volume: 32

    Topics: Lactates; Lactic Acid; Psoriasis

1961
[Lactic acid treatment of psoriasis].
    Wiener medizinische Wochenschrift (1946), 1960, Dec-31, Volume: 110

    Topics: Lactates; Lactic Acid; Psoriasis

1960
[Results of the treatment of psoriasis with lactic acid].
    Das Deutsche Gesundheitswesen, 1961, Feb-09, Volume: 16

    Topics: Lactates; Lactic Acid; Psoriasis

1961
[Clinical treatment of psoriasis with dextro-lactic acid].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1961, Volume: 12

    Topics: Lactates; Lactic Acid; Psoriasis

1961
[The treatment of psoriasis with dextrorotatory lactic acid].
    Archives belges de dermatologie et de syphiligraphie, 1962, Volume: 18

    Topics: Humans; Lactates; Lactic Acid; Psoriasis

1962
[Survey of recent procedures for the treatment of psoriasis vulgaris (vitamin D2, folic acid, lactic acid, etc.)].
    Die Therapiewoche, 1963, Volume: 13

    Topics: Data Collection; Drug Therapy; Ergocalciferols; Folic Acid; Humans; Lactates; Lactic Acid; Psoriasis

1963
[Dextro-rotarory lactic acid and racemic lactic acid in the treatment of psoriasis and parakeratotic dermatosis].
    Revista de la Asociacion Medica Argentina, 1961, Volume: 75

    Topics: Dermatology; Lactates; Lactic Acid; Psoriasis; Skin Diseases

1961
Irritant and toxic reactions to phenol in topical medications.
    Cutis, 1980, Volume: 26, Issue:4

    Topics: Adult; Aged; Candidiasis, Cutaneous; Dermatitis, Contact; Drug Combinations; Drug Eruptions; Eczema;

1980
Epilyt for scalp psoriasis.
    Archives of dermatology, 1991, Volume: 127, Issue:2

    Topics: Butylated Hydroxytoluene; Dermatologic Agents; Drug Combinations; Humans; Lactates; Lactic Acid; Pro

1991
[A case of idiopathic hypoparathyroidism associated with perceptive deafness and psoriasis vulgaris].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1988, Volume: 77, Issue:8

    Topics: Adult; Calcium Metabolism Disorders; Deafness; Humans; Hypoparathyroidism; Lactates; Lactic Acid; Ma

1988