azacitidine has been researched along with Cancer of Esophagus in 71 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (1.41) | 18.2507 |
2000's | 28 (39.44) | 29.6817 |
2010's | 41 (57.75) | 24.3611 |
2020's | 1 (1.41) | 2.80 |
Authors | Studies |
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Cai, HQ; Cai, Y; Chang, C; Chen, DX; Guo, J; Hao, JJ; Wang, JJ; Wang, MR; Wei, WQ; Yang, LY; Zhang, Y | 1 |
Li, JR; Li, SY; Sun, LL; Yang, SM; Yu, HB | 1 |
Chen, C; Liu, X; Ma, Z; Yu, Z; Zhang, H | 1 |
Bai, G; Bao, Y; Chu, J; Eli, M; Wen, H | 1 |
da Costa, NM; de Almeida Simão, T; Gonzaga, IM; Herceg, Z; Hernandez-Vargas, H; Nicolau, MC; Nicolau-Neto, P; Ribeiro Pinto, LF; Soares Lima, SC | 1 |
Ding, C; Dong, Z; Guo, W; Guo, Y; Liang, J; Liu, S; Shan, B; Shen, S | 1 |
He, J; Li, Y; Luo, M; Shi, X; Sun, N; Yang, W; Zhou, F | 1 |
Baba, H; Baba, Y; Eto, K; Hiyoshi, Y; Ishimoto, T; Iwagami, S; Iwatsuki, M; Kiyozumi, Y; Miyamoto, Y; Ogata, Y; Okadome, K; Watanabe, M; Yagi, T; Yoshida, N | 1 |
Bultmann, I; Conradi, A; Kretschmer, C; Sterner-Kock, A | 1 |
Cheng, Y; Dong, M; Fan, X; Feng, X; Jin, Z; Meltzer, SJ; Mori, Y; Wang, L; Zhang, X; Zhao, Z | 1 |
Cao, Z; Chen, S; Cheng, Y; Dong, M; Fan, X; Feng, X; Gao, Y; Jin, Z; Liu, J; Meltzer, SJ; Mori, Y; Wang, L; Yu, H; Zhang, X; Zhang, Y; Zhao, Z | 1 |
Akhtar, J; Chen, HX; Liu, H; Wang, S; Wang, Z | 1 |
Chen, X; Dong, W; Fan, Q; Huang, L; Li, F; Liu, J; Wang, F; Wang, L; Wang, M; Yue, D; Zhang, B; Zhang, Y; Zhang, Z | 1 |
Ling, Y; Liu, Y; Lu, M; Xu, Y; Zhang, C; Zhou, T; Zhu, C; Zhu, J | 1 |
Chen, HX; Liu, H; Wang, S; Wang, Z | 1 |
Cui, L; Dong, Z; Guo, W; Guo, Y; Kuang, G; Shen, S; Wang, C | 1 |
Dong, Z; Guo, W; Guo, Y; Kuang, G; Shen, S; Yang, Z; Zhang, M | 1 |
Cao, Z; Chen, S; Cheng, Y; Dong, M; Fan, X; Feng, X; Gao, Y; Jin, Z; Liu, J; Meltzer, SJ; Mori, Y; Wang, L; Wu, W; Yu, H; Zhang, X; Zhao, Z | 1 |
Hou, SY; Liu, WH; Sang, MX; Shan, BE; Zhang, C | 1 |
Dong, Z; Guo, W; Guo, X; Guo, Y; Kuang, G; Shen, S; Wang, C | 1 |
Ahrens, TD; Boerries, M; Busch, H; Follo, M; Hembach, S; Hoeppner, J; Hopt, UT; Lassmann, S; Ostendorp, J; Timme, S; Werner, M | 1 |
Dong, Z; Guo, W; Guo, X; Guo, Y; Kuang, G; Liang, J; Liu, Y; Shen, S | 1 |
Li, X; Liao, J; Liu, R; Pan, E; Pu, Y; Wang, Y; Yang, M; Yin, L | 1 |
Ahrens, TD; Bogatyreva, L; Hauschke, D; Hoeppner, J; Hopt, UT; Lassmann, S; Ostendorp, J; Timme, S; Werner, M | 1 |
Cao, Y; Chen, Y; Huang, Y; Li, G; Liu, Z | 1 |
Bao, Y; Chen, Z; Dong, H; Guo, Y; Li, K; Shen, K; Wang, Q; Yang, W; Yang, Y; Zhang, H | 1 |
Chen, J; Gao, J; Gu, X; Liu, T; Lü, L; Mei, Z; Zeng, H | 1 |
Baba, H; Baba, Y; Harada, K; Ishimoto, T; Iwatsuki, M; Kiyozumi, Y; Kosumi, K; Kurashige, J; Miyake, K; Nakamura, K; Nakao, M; Ohuchi, M; Sakamoto, Y; Shigaki, H; Watanabe, M; Yoshida, N | 1 |
He, H; He, Y; Jiang, D; Li, W; Ma, H; Niu, Z; Wu, D; Xie, X; Zuo, X | 1 |
Duan, Y; Han, X; Jia, Y; Liu, L; Lv, W; Ma, M; Wang, J; Wang, X; Wang, Y | 1 |
Arai, M; Imazeki, F; Mikata, R; Ochiai, T; Sakai, Y; Seki, N; Shimada, H; Tada, M; Yokosuka, O | 1 |
Chen, H; El-Rifai, W; Peng, DF; Razvi, M; Roessner, A; Schneider-Stock, R; Washington, K | 1 |
Abraham, JM; Agarwal, R; Beer, DG; Cheng, Y; David, S; Hamilton, JP; Ito, T; Jin, Z; Kan, T; Meltzer, SJ; Mori, Y; Olaru, A; Paun, B; Sato, F; Selaru, FM; Shimada, Y; Yang, J | 1 |
Bonazzi, VF; Hayward, NK; Irwin, D | 1 |
Drew, PA; Jones, ME; Smith, E | 1 |
Claesson, MH; Krishnadath, KK; Milano, F; Pedersen, AW; Weinert, BT; Zocca, MB | 1 |
He, Y; Li, P; Wang, J; Wang, Y; Zhang, S; Zhu, S | 1 |
Li, P; Meng, XY; Wang, YJ; Zhang, ST; Zhu, ST; Zong, Y | 1 |
Dong, ZM; Fang, XH; Ge, MH; Hu, FJ; Li, P; Ling, ZQ; Mao, WM; Zhao, X | 1 |
Jiao, Y; Li, P; Meng, Y; Wang, JX; Wang, QG; Zhang, ST; Zhu, ST | 1 |
El-Rifai, W; Hu, TL; Jiang, A; Moskaluk, CA; Peng, D; Schneider-Stock, R; Washington, MK | 1 |
He, YL; Wang, JX; Yang, S; Zhang, ST; Zhu, ST | 1 |
Deng, X; Jing, Z; Li, G; Wu, SX; Zou, CL | 1 |
Guo, LP; Li, LW; Li, XY; Lu, SX; Yu, XY; Zhou, Y | 1 |
Cui, YT; Dong, SW; He, Z; Liang, SJ; Liu, YM; Sun, P; Wang, S; Wang, YG; Zhang, P | 1 |
Cui, YT; Dong, SW; He, Z; Liang, DC; Liang, SJ; Liu, YM; Wang, S; Wang, YG; Zhang, P; Zhong, RR | 1 |
Li, P; Meng, XY; Wang, YJ; Zhang, ST; Zhou, QZ; Zhu, ST | 1 |
Chen, XY; Guo, MZ; He, QY | 1 |
Bartram, CR; Imamura, M; Imoto, I; Inazawa, J; Inoue, J; Janssen, JW; Shimada, Y; Ueda, M | 1 |
Hoque, MO; Meltzer, SJ; Mori, M; Osada, M; Sato, F; Sidransky, D; Upadhyay, S; Xiao, Y; Yamashita, K | 1 |
Amagasa, T; Chin, K; Gray, JW; Hirohashi, S; Imamura, M; Imoto, I; Inazawa, J; Inoue, J; Shibata, T; Shimada, Y; Sonoda, I | 1 |
Beer, DG; Chen, GA; Fischette, MR; Guo, ZS; Hong, JA; Kassis, ES; Lee, S; Nguyen, DM; Schrump, DS; Steiner, FA; Trepel, JB; Weiser, TS | 1 |
Chen, D; Christman, JK; Fang, MZ; Jin, Z; Sun, Y; Yang, CS | 1 |
Chan, AT; Langford, C; Li, H; Murray, P; Putti, T; Seng, TJ; Srivastava, G; Tao, Q; Tsao, SW; Ying, J | 1 |
Ding, F; Guo, M; Li, J; Li, W; Liu, Z; Wang, Y; Wu, M; Yu, Z; Zhan, Q; Zhang, L | 1 |
Benhattar, J; Bosman, FT; Braunschweig, R; Clément, G; Pasquier, N | 1 |
Chen, GA; Figg, WD; Fischette, MR; Hancox, A; Hong, JA; Kunst, TF; Li, X; Murgo, AJ; Nguyen, DM; Pishchik, V; Schrump, DS; Steinberg, SM; Zhao, M | 1 |
Abraham, JM; Cheng, Y; Greenwald, BD; Hamilton, JP; Ito, T; Jin, Z; Kan, T; Meltzer, SJ; Mori, Y; Paun, BC; Sato, F; Wang, S; Yang, J | 1 |
Chan, AT; Chan, SL; Cui, Y; Jin, H; Lee, KY; Li, H; Ng, KM; Rha, SY; Robertson, KD; Srivastava, G; Tao, Q; Tsao, GS; van Hasselt, A; Wang, Y; Zhong, S | 1 |
Asuncion, L; Csiszar, K; Dietzsch, E; Fong, KS; Fong, SF; He, Q; Hollosi, P; Parker, MI | 1 |
Aiko, S; Imoto, I; Inazawa, J; Inoue, J; Iwai, T; Kawano, T; Kozaki, K; Shimada, Y; Tanaka, K; Tsuda, H; Yoshizumi, Y | 1 |
Abraham, JM; Agarwal, R; Beer, D; Cheng, Y; David, S; Hamilton, JP; Ito, T; Jin, Z; Kan, T; Meltzer, SJ; Montgomery, E; Mori, Y; Olaru, A; Paun, B; Sato, F; Yang, J | 1 |
Li, K; Li, Z; Teng, L; Wei, L; Wu, K; Yu, P; Zhang, C; Zhu, J | 1 |
Agarwal, R; Hamilton, JP; Ito, T; Jin, Z; Kan, T; Meltzer, SJ; Mori, Y; Olaru, A; Sato, F; Yang, J | 1 |
Hu, J; Long, C; Lu, Q; Yang, Y; Yin, B; Yu, F; Yuan, Y; Zhou, X | 1 |
Fukuyoshi, Y; Inoue, H; Ishii, H; Kita, Y; Mimori, K; Mori, M; Motoyama, K; Ohta, M; Yamashita, K | 1 |
Fitzgerald, RC; Gjerset, RA; Huang, Y; Peters, CJ | 1 |
Harada, H; Hatooka, S; Imamura, M; Ishizaki, K; Shimada, Y; Shinoda, M; Tanaka, H | 1 |
Chen, GA; Fischette, MR; Guo, ZS; Hong, JA; Nguyen, DM; Ohnmacht, GA; Schrump, DS; Weiser, TS | 1 |
Liao, J; Nie, Y; So, C; Song, Y; Wang, LD; Yang, CS; Yang, G; Zhao, X | 1 |
Cheung, AL; Lam, KY; Liu, Y; Shen, ZY; Si, HX; Srivastava, G; Tsao, SW; Wong, YC | 1 |
1 trial(s) available for azacitidine and Cancer of Esophagus
Article | Year |
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Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura.
Topics: Adult; Aged; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Decitabine; DNA Modification Methylases; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Genes, p16; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Membrane Proteins; Mesothelioma; Middle Aged; Neoplasm Proteins; Pleural Neoplasms; Transcriptional Activation | 2006 |
70 other study(ies) available for azacitidine and Cancer of Esophagus
Article | Year |
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Dysregulation of CXCL14 promotes malignant phenotypes of esophageal squamous carcinoma cells via regulating SRC and EGFR signaling.
Topics: Azacitidine; Cell Line, Tumor; Cell Proliferation; Chemokines, CXC; DNA Methylation; ErbB Receptors; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Gene Expression Regulation, Neoplastic; Humans; Phenotype | 2022 |
Repression of DOK7 mediated by DNMT3A promotes the proliferation and invasion of KYSE410 and TE-12 ESCC cells.
Topics: Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Muscle Proteins; Neoplasm Invasiveness; Promoter Regions, Genetic | 2017 |
Krüppel-Like Factor 4 Enhances Sensitivity of Cisplatin to Esophageal Squamous Cell Carcinoma (ESCC) Cells.
Topics: Antineoplastic Agents; Apoptosis; Azacitidine; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Line, Tumor; Cisplatin; DNA Methylation; Drug Resistance, Neoplasm; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Gene Silencing; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Promoter Regions, Genetic | 2017 |
PAQR3 overexpression suppresses the aggressive phenotype of esophageal squamous cell carcinoma cells via inhibition of ERK signaling.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Male; MAP Kinase Signaling System; Membrane Proteins; Mice; Mice, Nude; Middle Aged; Neoplasm Staging; Phenotype; RNA, Messenger; Signal Transduction | 2017 |
Topics: Adult; Aged; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Down-Regulation; Early Detection of Cancer; Epigenesis, Genetic; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Promoter Regions, Genetic; Trefoil Factor-1 | 2017 |
Aberrant methylation-mediated silencing of lncRNA CTC-276P9.1 is associated with malignant progression of esophageal squamous cell carcinoma.
Topics: Adult; Aged; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; CpG Islands; Disease Progression; DNA Methylation; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Silencing; Humans; Luciferases; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; RNA, Long Noncoding; Sp1 Transcription Factor; Survival Analysis; Up-Regulation | 2018 |
Aberrant methylation of EYA4 promotes epithelial-mesenchymal transition in esophageal squamous cell carcinoma.
Topics: Animals; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; DNA Methylation; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice, Nude; Middle Aged; RNA Interference; Trans-Activators; Transplantation, Heterologous | 2018 |
Indoleamine 2, 3-dioxygenase 1 promoter hypomethylation is associated with poor prognosis in patients with esophageal cancer.
Topics: Aged; Azacitidine; Cell Line, Tumor; DNA Methylation; Enzyme Inhibitors; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Male; Middle Aged; Prognosis; Promoter Regions, Genetic | 2019 |
Latent transforming growth factor β-binding protein 4 is downregulated in esophageal cancer via promoter methylation.
Topics: Azacitidine; Base Sequence; Binding Sites; Carcinoma; Cell Line, Tumor; Cell Movement; Decitabine; Disease Progression; DNA Methylation; Down-Regulation; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Gene Order; Humans; Latent TGF-beta Binding Proteins; Neoplasm Staging; Promoter Regions, Genetic; Protein Binding; Transcription Factors; Transforming Growth Factor beta1 | 2013 |
Endoglin promoter hypermethylation identifies a field defect in human primary esophageal cancer.
Topics: Adenocarcinoma; Aged; Antigens, CD; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Decitabine; DNA Methylation; Endoglin; Esophageal Neoplasms; Esophagus; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Staging; Prognosis; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; ROC Curve; Tumor Cells, Cultured | 2013 |
MAL hypermethylation is a tissue-specific event that correlates with MAL mRNA expression in esophageal carcinoma.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Azacitidine; Barrett Esophagus; Carcinoma, Squamous Cell; Case-Control Studies; Decitabine; DNA Methylation; Esophageal Neoplasms; Esophagus; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Myelin and Lymphocyte-Associated Proteolipid Proteins; Neoplasm Grading; Prognosis; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; ROC Curve; Tumor Cells, Cultured | 2013 |
Alteration of runt-related transcription factor 3 gene expression and biologic behavior of esophageal carcinoma TE-1 cells after 5-azacytidine intervention.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Carcinoma, Squamous Cell; Cell Adhesion; Cell Movement; Cell Proliferation; Core Binding Factor Alpha 3 Subunit; DNA Methylation; DNA, Neoplasm; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2013 |
Epigenetic inactivation of SPINT2 is associated with tumor suppressive function in esophageal squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Carcinoma, Squamous Cell; DNA Methylation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Male; Membrane Glycoproteins; Middle Aged; Promoter Regions, Genetic; Tumor Cells, Cultured | 2014 |
Promoter methylation‑associated silencing of p27kip1 gene with metastasis in esophageal squamous cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Decitabine; DNA Methylation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Expression Regulation; Gene Silencing; Humans; Lymphatic Metastasis; Male; Promoter Regions, Genetic; RNA, Messenger | 2014 |
Effects of 5-azacytidine on RUNX3 gene expression and the biological behavior of esophageal carcinoma cells.
Topics: Animals; Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Core Binding Factor Alpha 3 Subunit; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Xenograft Model Antitumor Assays | 2014 |
Decreased expression of RASSF1A and up-regulation of RASSF1C is associated with esophageal squamous cell carcinoma.
Topics: Adult; Aged; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Esophageal Neoplasms; Exons; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasm Metastasis; Neoplasm Staging; Promoter Regions, Genetic; RNA, Messenger; Tumor Suppressor Proteins | 2014 |
Aberrant methylation and decreased expression of the TGF-β/Smad target gene FBXO32 in esophageal squamous cell carcinoma.
Topics: Adult; Aged; Azacitidine; Calmodulin-Binding Proteins; Carcinoma, Squamous Cell; Cell Growth Processes; Decitabine; DNA Methylation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Silencing; Humans; Hydroxamic Acids; Immunohistochemistry; Male; Middle Aged; Muscle Proteins; Promoter Regions, Genetic; RNA, Messenger; SKP Cullin F-Box Protein Ligases; Smad Proteins; Transforming Growth Factor beta; Up-Regulation | 2014 |
Temporal evolution in caveolin 1 methylation levels during human esophageal carcinogenesis.
Topics: Adenocarcinoma; Area Under Curve; Azacitidine; Barrett Esophagus; Carcinoma, Squamous Cell; Caveolin 1; Cell Line, Tumor; Decitabine; Disease Progression; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; RNA, Messenger; ROC Curve; Time Factors | 2014 |
Low-dose decitabine induces MAGE-A expression and inhibits invasion via suppression of NF-κB2 and MMP2 in Eca109 cells.
Topics: Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Neoplasm Proteins; NF-kappa B p52 Subunit | 2014 |
RASSF5A, a candidate tumor suppressor, is epigenetically inactivated in esophageal squamous cell carcinoma.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Alternative Splicing; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cytidine Triphosphate; DNA Methylation; Esophageal Neoplasms; Esophagus; Female; Genes, Tumor Suppressor; Genetic Predisposition to Disease; Humans; Hydroxamic Acids; Male; Middle Aged; Monomeric GTP-Binding Proteins; Neoplasm Invasiveness; Prognosis; Promoter Regions, Genetic; Protein Isoforms; Protein Synthesis Inhibitors; RNA, Messenger, Stored | 2015 |
Selective inhibition of esophageal cancer cells by combination of HDAC inhibitors and Azacytidine.
Topics: Acetylation; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Benzamides; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Survival; Decitabine; Depsipeptides; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Pyridines; Transcriptome; Vorinostat | 2015 |
Methylation-mediated repression of potential tumor suppressor miR-203a and miR-203b contributes to esophageal squamous cell carcinoma development.
Topics: Adult; Aged; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; CpG Islands; DNA Methylation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Expression Regulation, Neoplastic; Humans; Lymphatic Metastasis; Male; MicroRNAs; Middle Aged; Prognosis; Promoter Regions, Genetic | 2016 |
Epigenetic Repression of miR-218 Promotes Esophageal Carcinogenesis by Targeting ROBO1.
Topics: 3' Untranslated Regions; Azacitidine; Base Sequence; Binding Sites; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; CpG Islands; DNA Methylation; Epigenetic Repression; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Gene Order; Genetic Loci; Humans; MicroRNAs; Nerve Tissue Proteins; Receptors, Immunologic; RNA Interference; RNA, Messenger; Roundabout Proteins | 2015 |
Response of esophageal cancer cells to epigenetic inhibitors is mediated via altered thioredoxin activity.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Carrier Proteins; Cell Line, Tumor; Epigenesis, Genetic; Esophageal Neoplasms; Female; Histone Deacetylase Inhibitors; Humans; Male; Middle Aged; Reactive Oxygen Species; Thioredoxin Reductase 1; Thioredoxins | 2016 |
In vitro study of human mutL homolog 1 hypermethylation in inducing drug resistance of esophageal carcinoma.
Topics: Azacitidine; Cell Line, Tumor; Cisplatin; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Esophageal Neoplasms; Humans; MutL Protein Homolog 1; Promoter Regions, Genetic; RNA, Messenger | 2017 |
PRSS8 methylation and its significance in esophageal squamous cell carcinoma.
Topics: Azacitidine; Base Sequence; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; Disease-Free Survival; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Male; Middle Aged; Promoter Regions, Genetic; RNA Interference; Sequence Homology, Nucleic Acid; Serine Endopeptidases | 2016 |
Aberrant methylation of microRNA-193b in human Barrett's esophagus and esophageal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Azacitidine; Barrett Esophagus; Biomarkers, Tumor; Cell Line, Tumor; DNA Methylation; Down-Regulation; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Immunohistochemistry; Male; MicroRNAs; Middle Aged; Promoter Regions, Genetic | 2016 |
UHRF1 regulates global DNA hypomethylation and is associated with poor prognosis in esophageal squamous cell carcinoma.
Topics: Aged; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; CCAAT-Enhancer-Binding Proteins; Cell Transformation, Neoplastic; Disease-Free Survival; DNA Methylation; Epigenesis, Genetic; Epigenomics; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagus; Female; Humans; Long Interspersed Nucleotide Elements; Male; Middle Aged; Prognosis; Proportional Hazards Models; Sequence Analysis, DNA; Treatment Outcome; Ubiquitin; Ubiquitin-Protein Ligases | 2016 |
5-Azacytidine suppresses EC9706 cell proliferation and metastasis by upregulating the expression of SOX17 and CDH1.
Topics: Antigens, CD; Azacitidine; Cadherins; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Metastasis; Promoter Regions, Genetic; SOXF Transcription Factors; Up-Regulation | 2016 |
Methylation decreases the Bin1 tumor suppressor in ESCC and restoration by decitabine inhibits the epithelial mesenchymal transition.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Cycle; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Lymphatic Metastasis; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Nuclear Proteins; Prognosis; Promoter Regions, Genetic; Signal Transduction; Survival Rate; Tumor Cells, Cultured; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2017 |
Analysis of the methylation status of genes up-regulated by the demethylating agent, 5-aza-2'-deoxycytidine, in esophageal squamous cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cathepsin L; Cathepsins; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cysteine Endopeptidases; Decitabine; DNA Methylation; DNA Modification Methylases; Esophageal Neoplasms; Esophagus; Fatty Acid-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Nuclear Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Barrett Esophagus; Cell Transformation, Neoplastic; CpG Islands; Decitabine; Disease Progression; DNA Methylation; DNA, Neoplasm; Down-Regulation; Epigenesis, Genetic; Esophageal Neoplasms; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Glutathione Transferase; Humans; Hydroxamic Acids; Middle Aged; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 2009 |
Promoter hypermethylation of CDH13 is a common, early event in human esophageal adenocarcinogenesis and correlates with clinical risk factors.
Topics: Adenocarcinoma; Azacitidine; Base Sequence; Cadherins; Cell Line, Tumor; DNA Methylation; DNA Primers; Esophageal Neoplasms; Female; Humans; Male; Middle Aged; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors | 2008 |
Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma.
Topics: Azacitidine; Carrier Proteins; Cell Line, Tumor; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; Esophageal Neoplasms; Gene Expression Profiling; Gene Silencing; Genes, Tumor Suppressor; Glioma; Heat-Shock Proteins; Humans; Hydroxamic Acids; Intracellular Signaling Peptides and Proteins; Melanoma; Membrane Proteins; Microfilament Proteins; Neuropeptides; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Phosphoprotein Phosphatases; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Quantitation of DNA methylation by melt curve analysis.
Topics: Algorithms; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; DNA, Neoplasm; Esophageal Neoplasms; Hot Temperature; Humans; Immunohistochemistry; Nucleic Acid Denaturation; Oligonucleotides; Polymerase Chain Reaction; Promoter Regions, Genetic; Tissue Inhibitor of Metalloproteinase-3; Tumor Suppressor Proteins | 2009 |
Real-time PCR analysis of genes encoding tumor antigens in esophageal tumors and a cancer vaccine.
Topics: Aged; Antigens, Neoplasm; Azacitidine; Cancer Vaccines; Carcinoma, Squamous Cell; Clone Cells; Decitabine; DNA Modification Methylases; Epithelial Cells; Esophageal Neoplasms; Female; Gene Expression Profiling; Humans; Male; Middle Aged; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Identification of GPX3 epigenetically silenced by CpG methylation in human esophageal squamous cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Glutathione Peroxidase; Humans; Male; Middle Aged; Promoter Regions, Genetic; Tumor Suppressor Proteins | 2011 |
Promoter hypermethylation of cyclooxygenase-2 gene in esophageal squamous cell carcinoma.
Topics: Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclooxygenase 2; Decitabine; Dinoprostone; DNA Methylation; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Promoter Regions, Genetic; RNA, Messenger; Sequence Analysis, DNA | 2011 |
Hypermethylation-modulated down-regulation of CDH1 expression contributes to the progression of esophageal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Azacitidine; Cadherins; Carcinoma, Squamous Cell; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Shape; Cell Survival; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Esophageal Neoplasms; Female; Humans; Male; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Promoter Regions, Genetic; Transcription, Genetic | 2011 |
Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Esophageal Neoplasms; Gene Silencing; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Membrane Proteins | 2011 |
Location-specific epigenetic regulation of the metallothionein 3 gene in esophageal adenocarcinomas.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Azacitidine; Cell Line, Tumor; CpG Islands; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Histones; Humans; Lymphatic Metastasis; Metallothionein 3; Middle Aged; Neoplasm Staging; Nerve Tissue Proteins; Promoter Regions, Genetic; Protein Processing, Post-Translational; Repressor Proteins | 2011 |
Aberrant methylation of the 3q25 tumor suppressor gene PTX3 in human esophageal squamous cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; C-Reactive Protein; Carcinoma, Squamous Cell; Cell Line, Tumor; Chromosomes, Human, Pair 3; Decitabine; DNA Methylation; Down-Regulation; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Serum Amyloid P-Component | 2011 |
[Aberrant methylation of T-cadherin gene in human esophageal carcinoma cells].
Topics: Azacitidine; Cadherins; Cell Line, Tumor; DNA Methylation; Esophageal Neoplasms; Humans; Promoter Regions, Genetic | 2011 |
[Mechanism of loss of human esophageal cancer-related gene 4 (ECRG4) gene expression in esophageal squamous cell carcinoma cell line EC9706].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Esophageal Neoplasms; Exons; Gene Expression Regulation, Neoplastic; Humans; Mutation; Neoplasm Proteins; Oxides; Promoter Regions, Genetic; RNA, Messenger; Tumor Suppressor Proteins | 2011 |
Study on RIZ1 gene promoter methylation status in human esophageal squamous cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Esophageal Neoplasms; Female; Gene Silencing; Histone-Lysine N-Methyltransferase; Humans; Male; Middle Aged; Molecular Sequence Data; Nuclear Proteins; Promoter Regions, Genetic; Sequence Analysis, DNA; Transcription Factors | 2012 |
Decreased expression of retinoblastoma protein-interacting zinc-finger gene 1 in human esophageal squamous cell cancer by DNA methylation.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; DNA-Binding Proteins; Drug Screening Assays, Antitumor; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone-Lysine N-Methyltransferase; Humans; Molecular Sequence Data; Nuclear Proteins; RNA, Messenger; Transcription Factors | 2012 |
Promoter methylation regulates cigarette smoke-stimulated cyclooxygenase-2 expression in esophageal squamous cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclooxygenase 2; Decitabine; DNA Methylation; Esophageal Neoplasms; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Smoking | 2012 |
XAF1 is frequently methylated in human esophageal cancer.
Topics: Adaptor Proteins, Signal Transducing; Aged; Apoptosis Regulatory Proteins; Azacitidine; Biomarkers, Tumor; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Chi-Square Distribution; China; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neoplasm Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
MYEOV, a gene at 11q13, is coamplified with CCND1, but epigenetically inactivated in a subset of esophageal squamous cell carcinomas.
Topics: Azacitidine; Blotting, Northern; Blotting, Southern; Carcinoma, Squamous Cell; Chromosomes, Human, Pair 11; Cyclin D1; Decitabine; DNA Methylation; Esophageal Neoplasms; Gene Amplification; Gene Silencing; Humans; Neoplasm Proteins; Oncogene Proteins; Proto-Oncogene Proteins; Tumor Cells, Cultured | 2002 |
Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.
Topics: Azacitidine; Base Sequence; Carcinoma, Squamous Cell; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Hydroxamic Acids; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2002 |
Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma.
Topics: Acetylation; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Division; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Esophageal Neoplasms; Gene Deletion; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Nucleic Acid Hybridization; Receptors, LDL; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
Sequential 5-Aza 2'-deoxycytidine/depsipeptide FK228 treatment induces tissue factor pathway inhibitor 2 (TFPI-2) expression in cancer cells.
Topics: Azacitidine; Base Sequence; Cell Line, Tumor; Decitabine; Depsipeptides; DNA Primers; Esophageal Neoplasms; Glycoproteins; Humans; Lung Neoplasms | 2005 |
Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Esophageal Neoplasms; Genistein; Glycine max; Humans; Hydroxamic Acids; Isoflavones; Isothiocyanates; O(6)-Methylguanine-DNA Methyltransferase; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfites; Sulfoxides; Tea; Thiocyanates | 2005 |
Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation.
Topics: Azacitidine; Cadherins; Carcinoma; Cell Movement; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Epigenesis, Genetic; Esophageal Neoplasms; Gene Silencing; Genes, Tumor Suppressor; Humans; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Protocadherins; Sequence Deletion; Transcription, Genetic | 2006 |
5-Aza-2'-deoxycytidine induces retinoic acid receptor-beta(2) demethylation and growth inhibition in esophageal squamous carcinoma cells.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Decitabine; DNA Methylation; DNA Modification Methylases; Esophageal Neoplasms; Esophagus; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Receptors, Retinoic Acid; RNA, Messenger | 2005 |
Alterations of the Wnt signaling pathway during the neoplastic progression of Barrett's esophagus.
Topics: Adenocarcinoma; Azacitidine; Barrett Esophagus; beta Catenin; Cell Division; Cell Line, Tumor; CpG Islands; Decitabine; Disease Progression; DNA Methylation; DNA, Neoplasm; Esophageal Neoplasms; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, APC; Humans; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Mucous Membrane; Neoplasm Proteins; Precancerous Conditions; Promoter Regions, Genetic; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Signal Transduction; Transfection; Wnt Proteins; Wnt2 Protein | 2006 |
Reprimo methylation is a potential biomarker of Barrett's-Associated esophageal neoplastic progression.
Topics: Adenocarcinoma; Aged; Azacitidine; Barrett Esophagus; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Line, Tumor; Decitabine; Disease Progression; DNA Methylation; Esophageal Diseases; Esophageal Neoplasms; Female; Genetic Markers; Glycoproteins; Humans; Male; Middle Aged; Polymerase Chain Reaction; Precancerous Conditions | 2006 |
The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas.
Topics: Adaptor Proteins, Signal Transducing; Animals; Azacitidine; Biomarkers, Tumor; Carcinoma; Cell Line; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Down-Regulation; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Repressor Proteins; Tumor Suppressor Proteins; Wnt1 Protein | 2007 |
Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Oxidoreductases; Azacitidine; Blotting, Western; Cell Differentiation; Cell Line; Colonic Neoplasms; CpG Islands; Decitabine; DNA Primers; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Loss of Heterozygosity; Male; Middle Aged; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Frequent methylation-associated silencing of a candidate tumor-suppressor, CRABP1, in esophageal squamous-cell carcinoma.
Topics: Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Differentiation; Cell Proliferation; DNA Methylation; Epigenesis, Genetic; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lymphatic Metastasis; Male; Middle Aged; Promoter Regions, Genetic; Receptors, Retinoic Acid | 2007 |
Hypermethylation of the nel-like 1 gene is a common and early event and is associated with poor prognosis in early-stage esophageal adenocarcinoma.
Topics: Aged; Azacitidine; Calcium-Binding Proteins; Cell Line, Tumor; Cytidine Triphosphate; DNA Methylation; Esophageal Neoplasms; Humans; Middle Aged; Neoplasm Staging; Nerve Tissue Proteins; Prognosis; Promoter Regions, Genetic; RNA, Messenger; Survival Rate; Time Factors | 2007 |
p300 expression repression by hypermethylation associated with tumour invasion and metastasis in oesophageal squamous cell carcinoma.
Topics: Azacitidine; Carcinoma, Squamous Cell; Decitabine; DNA Methylation; DNA, Neoplasm; E1A-Associated p300 Protein; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lymphatic Metastasis; Male; Neoplasm Invasiveness; Neoplasm Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm | 2007 |
Hypermethylation of the somatostatin promoter is a common, early event in human esophageal carcinogenesis.
Topics: Azacitidine; Barrett Esophagus; Cell Line, Tumor; DNA Methylation; Esophageal Neoplasms; Gene Silencing; Humans; Polymerase Chain Reaction; Promoter Regions, Genetic; Somatostatin | 2008 |
Promoter hypermethylation of the RUNX3 gene in esophageal squamous cell carcinoma.
Topics: Aged; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Core Binding Factor Alpha 3 Subunit; DNA Methylation; Esophageal Neoplasms; Female; Humans; Male; Middle Aged; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta | 2007 |
Clinical significance of the reduced expression of G protein gamma 7 (GNG7) in oesophageal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Cell Line, Tumor; Chromosomes, Human, Pair 19; DNA Methylation; Down-Regulation; Esophageal Neoplasms; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; GTP-Binding Protein gamma Subunits; Humans; Loss of Heterozygosity; Male; MicroRNAs; Middle Aged; Neoplasm Invasiveness; Prognosis; RNA, Messenger | 2008 |
Progressive silencing of p14ARF in oesophageal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Barrett Esophagus; Base Sequence; Cell Line; Decitabine; Disease Progression; Epithelial Cells; Esophageal Neoplasms; Female; Gene Silencing; Histones; Humans; Male; Methylation; Middle Aged; Molecular Sequence Data; Survival Rate; Tumor Suppressor Protein p14ARF | 2009 |
Methylation of the 5' CpG island of the FHIT gene is closely associated with transcriptional inactivation in esophageal squamous cell carcinomas.
Topics: Acid Anhydride Hydrolases; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Carcinoma, Squamous Cell; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Esophageal Neoplasms; Exons; Gene Deletion; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Neoplasm Proteins; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proteins; Transcriptional Activation; Tumor Cells, Cultured | 1998 |
Induction of MAGE-3 expression in lung and esophageal cancer cells.
Topics: Adenocarcinoma; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antigens, Neoplasm; Azacitidine; Carcinoma, Non-Small-Cell Lung; Decitabine; Depsipeptides; DNA Modification Methylases; Enzyme Inhibitors; Esophageal Neoplasms; Histone Deacetylase Inhibitors; Humans; Immunohistochemistry; Lung Neoplasms; Melanoma; Neoplasm Proteins; Peptides, Cyclic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2001 |
DNA hypermethylation is a mechanism for loss of expression of the HLA class I genes in human esophageal squamous cell carcinomas.
Topics: Azacitidine; Carcinoma, Squamous Cell; Chromosomes, Human, Pair 6; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Primers; DNA, Neoplasm; Down-Regulation; Esophageal Neoplasms; Gene Deletion; Genes, MHC Class I; Histocompatibility Antigens Class I; Humans; Immunoenzyme Techniques; Loss of Heterozygosity; Microsatellite Repeats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
E-cadherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells.
Topics: Azacitidine; Cadherins; Carcinoma; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Enzyme Inhibitors; Esophageal Neoplasms; Humans; Promoter Regions, Genetic; RNA, Neoplasm; Transcription, Genetic; Tumor Cells, Cultured | 2001 |