diallylnitrosamine profile

ID Source	ID
PubMed CID	27821
CHEMBL ID	164131
SCHEMBL ID	3210308
MeSH ID	M0064169

Synonym
wln: 1u2nno&2u1
nsc37648
2-propen-1-amine, n-nitroso-n-2-propenyl-
nsc-37648
16338-97-9
diallylamine, n-nitroso-
n-nitrosodiallylamine
diallylnitrosamine
diallylnitrosamin
n-diallylnitrosamine
n-nitroso-n,n-diallylamine
n-nitroso-n-prop-2-en-1-ylprop-2-en-1-amine
n-diallynitrosamine
ccris 6153
nitrosodiallyamine
n-nitrosodiallyl amine
diallylnitrosamin [german]
brn 1922991
nsc 37648
CHEMBL164131
n,n-bis(prop-2-enyl)nitrous amide
AKOS006277388
n-nitroso-n-diallylamine
SCHEMBL3210308
nitrosodiallylamine
GRYFJBRXMFVEIL-UHFFFAOYSA-N
DTXSID2020395
1,1-diallyl-2-oxohydrazine
n,n-di(prop-2-enyl)nitrous amide
Q63088177
QZ22XCT9RV
nitrosodiallylamine, n-

Assay ID	Title	Year	Journal	Article
AID226733	Carcinogenic potency modelled in silico, (- = non-carcinogen)	1982	Journal of medicinal chemistry, Jul, Volume: 25, Issue:7	Computer-assisted studies of structure-activity relationships of N-nitroso compounds using pattern recognition.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	8 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	8 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
diethylnitrosamine Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.. N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.	2.36	2	nitrosamine	carcinogenic agent; hepatotoxic agent; mutagen
n-nitrosomorpholine N-nitrosomorpholine : A nitrosamine that is morpholine in which the hydrogen attached to the nitrogen is replaced by a nitroso group. A carcinogen and mutagen, it is found in snuff tobacco.	1.96	1	nitrosamine	carcinogenic agent; mutagen
dimethylnitrosamine Dimethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties. It causes serious liver damage and is a hepatocarcinogen in rodents.	2.37	2	nitrosamine	geroprotector; mutagen
n-nitrosodiphenylamine N-nitrosodiphenylamine: RN given refers to parent cpd; structure in first source	1.96	1	phenylhydrazines
n-nitrosopiperidine N-nitrosopiperidine: structure. N-nitrosopiperidine : A nitrosamine that is piperidine in which the hydrogen attached to the nitrogen is replaced by a nitroso group. One of the many carcinogens detected in cigarette smoke, it is found in meat, cheese and spices that have been treated with the preservative sodium nitrite.	1.96	1	nitrosamine; piperidine	apoptosis inducer; carcinogenic agent; environmental contaminant; mutagen
n,n'-dinitrosopiperazine N,N'-dinitrosopiperazine: RN given refers to unlabeled cpd	1.96	1
diisopropylnitrosamine [no description available]	1.96	1
n-methyl-n-nitrosoaniline N-methyl-N-nitrosoaniline: structure	1.96	1
n-nitroso(di-n-propyl)amine [no description available]	2.88	4	nitroso compound
dibutylnitrosamine dibutylnitrosamine: structure	2.37	2	nitroso compound
n-nitrosopyrrolidine N-Nitrosopyrrolidine: Carcinogenic nitrosamine that may be formed from preservatives in meats during their preparation or in the liver during metabolism.	1.96	1	pyrrolidines
n-nitrosoperhydroazepine [no description available]	1.96	1
nitrosobenzylmethylamine nitrosobenzylmethylamine: structure	2.37	2
n-nitrosodiethanolamine [no description available]	2.36	2	nitroso compound
n-nitroso-2,6-dimethylmorpholine N-nitroso-2,6-dimethylmorpholine: RN given refers to parent cpd without isomeric designation	1.96	1
butylhydroxybutylnitrosamine Butylhydroxybutylnitrosamine: A substituted carcinogenic nitrosamine.. N-butyl-N-(4-hydroxybutyl)nitrosamine : A nitrosamine that has butyl and 4-hydroxybutyl substituents. In mice, it causes high-grade, invasive cancers in the urinary bladder, but not in any other tissues.	1.96	1	nitrosamine; primary alcohol	carcinogenic agent
n-nitroso-n-methylvinylamine N-nitroso-N-methylvinylamine: structure given in first source	1.96	1	nitroso compound
n-nitrosodibenzylamine N-nitrosodibenzylamine: structure	1.96	1
n-nitroso-n-methylcyclohexylamine [no description available]	1.96	1
1-nitrosopiperazine [no description available]	1.96	1	phytanoyl-CoAs
nitrosomethyl-n-butylamine nitrosomethyl-N-butylamine: RN given refers to parent cpd	1.96	1
meladrazine nitrosoproline: RN given refers to 1-nitroso-L-proline	1.96	1
methylethylnitrosamine [no description available]	1.96	1	nitroso compound
n-ethyl-n-hydroxyethylnitrosamine N-ethyl-N-(2-hydroxyethyl)nitrosamine : A nitrosamine that is N-nitrosodiethylamine in which one of the ethyl froups has been replaced by a 2-hydroxyethyl group. It is used to induce renal and liver tumours in rodents.	1.96	1	nitrosamine; primary alcohol	carcinogenic agent
n-amyl-n-methylnitrosamine N-methyl-N-pentylnitrosamine : A nitrosamine that has methyl and pentyl substituents. It is a potent oesophageal carcinogen.	1.96	1	nitrosamine	carcinogenic agent
vinylethylnitrosamine [no description available]	1.96	1
n-nitrososarcosine N-nitrososarcosine : A nitrosamine that is sarcosine in which the hydrogen attached to the nitrogen has been replaced by a nitroso group.	1.96	1	nitrosamine; non-proteinogenic amino acid derivative	carcinogenic agent
trinitrosotrimethylenetriamine [no description available]	1.96	1	1,3,5-triazinanes; nitrosamine
n-nitroso-n'-methylpiperazine [no description available]	1.96	1
n'-nitrosonornicotine N'-nitrosonornicotine: structure; a potent carcinogen in laboratory animals	1.96	1	pyridines; pyrrolidines
n-nitrosoephedrine [no description available]	1.96	1
n-nitrosoheptamethyleneimine [no description available]	1.96	1	nitrosamine
diisopropanolnitrosamine diisopropanolnitrosamine: experimental carcinogen. N,N-bis(2-hydroxypropyl)nitrosamine : A nitrosamine that is dipropylamine in which the hydrogen attached to the nitrogen has been replaced by a nitroso group. It is a genotoxic carcinogen, targeting the lung, liver, thyroid, and kidney.	1.96	1	diol; nitrosamine; secondary alcohol	carcinogenic agent
n-nitrosomethyldodecylamine N-nitrosomethyldodecylamine: product of reaction of dimethyl-n-dodecylamine with nitrous acid	1.96	1
n,n-dinitrosohomopiperazine [no description available]	1.96	1
methyl(acetoxymethyl)nitrosamine methyl(acetoxymethyl)nitrosamine: RN given refers to parent cpd; structure in seventh source	1.96	1
nitrosobis(2-oxopropyl)amine nitrosobis(2-oxopropyl)amine: structure. nitrosobis(2-oxopropyl)amine : A nitrosamine that is iminodiacetone that is substituted by a nitroso group at the N-atom. It induces pancreatic ductal adenocarcinomas in Syrian golden hamsters (other rodents are not susceptible).	1.96	1	ketone; nitrosamine	carcinogenic agent
n-nitrosoguvacoline N-nitrosoguvacoline: formed by nitrosation of arecoline	1.96	1	citraconoyl group
n-nitrososarcosine ethyl ester [no description available]	1.96	1
2-hydroxypropyl-n-propylnitrosamine [no description available]	1.96	1
2-oxopropyl-n-propylnitrosamine [no description available]	1.96	1
3-nitrosomethylaminopyridine 3-nitrosomethylaminopyridine: structure	1.96	1
n-nitrosoallyl-2,3-dihydroxypropylamine N-nitrosoallyl-2,3-dihydroxypropylamine: structure given in first source	1.96	1
2-nitrosomethylaminopyridine 2-nitrosomethylaminopyridine: structure	1.96	1
4-nitrosomethylaminopyridine 4-nitrosomethylaminopyridine: structure	1.96	1
n,n-diamylnitrosamine [no description available]	1.96	1

Condition	Relationship Strength	Studies
Cancer of Esophagus [description not available]	1.96	1
Experimental Hepatoma [description not available]	1.96	1
Cancer of Nose [description not available]	2.65	3
Esophageal Neoplasms Tumors or cancer of the ESOPHAGUS.	1.96	1
Cancer of Larynx [description not available]	1.95	1
Experimental Neoplasms [description not available]	1.95	1
Tracheal Neoplasms New abnormal growth of tissue in the TRACHEA.	1.95	1
Respiratory Tract Neoplasms New abnormal growth of tissue in the RESPIRATORY SYSTEM.	1.95	1
Laryngeal Neoplasms Cancers or tumors of the LARYNX or any of its parts: the GLOTTIS; EPIGLOTTIS; LARYNGEAL CARTILAGES; LARYNGEAL MUSCLES; and VOCAL CORDS.	1.95	1
Neoplasms, Otorhinolaryngologic [description not available]	1.96	1
Adenocarcinoma, Basal Cell [description not available]	2.37	2
Cancer of Liver [description not available]	1.96	1
Papilloma, Squamous Cell [description not available]	2.37	2
Adenocarcinoma A malignant epithelial tumor with a glandular organization.	2.37	2
Liver Neoplasms Tumors or cancer of the LIVER.	1.96	1
Papilloma A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)	2.37	2
Carcinoma, Anaplastic [description not available]	1.96	1
Carcinoma, Epidermoid [description not available]	1.96	1
Carcinoma A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.	1.96	1
Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)	1.96	1

diallylnitrosamine

Cross-References

Synonyms (32)

Bioassays (1)

Research

Studies (8)

Market Indicators

Research Demand Index: 12.25

Study Types

diallylnitrosamine

Cross-References

Synonyms (32)

Bioassays (1)

Research

Studies (8)

Market Indicators

Research Demand Index: 12.25

Study Types

Related Drugs (46)

Related Conditions (20)