Page last updated: 2024-11-03

propofol and Cancer of Esophagus

propofol has been researched along with Cancer of Esophagus in 23 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Interruption of sedation due to a poor response to modified neuroleptanalgesia (m-NLA) with midazolam often occurs during endoscopic submucosal dissection (ESD) for esophageal squamous cell carcinoma (ESCC) because most patients have a history of heavy alcohol intake."9.27Comparison of propofol with midazolam in endoscopic submucosal dissection for esophageal squamous cell carcinoma: a randomized controlled trial. ( Arakawa, T; Fujiwara, Y; Fukunaga, S; Kamata, N; Kato, K; Machida, H; Maruyama, H; Minamino, H; Nagami, Y; Ominami, M; Sakai, T; Shiba, M; Sugimori, S; Tanaka, F; Tanigawa, T; Tominaga, K; Watanabe, T; Yamagami, H, 2018)
"BACKGROUND This study was done to verify whether propofol could inhibit esophageal squamous cell carcinoma (ESCC) cell line EC9706 cell migration and invasion by targeting SOX4."7.85Propofol Suppresses Esophageal Squamous Cell Carcinoma Cell Migration and Invasion by Down-Regulation of Sex-Determining Region Y-box 4 (SOX4). ( Ji, P; Li, JJ; Zhou, CL, 2017)
"We present a case of severe hyperkalemia in a 48-year-old man after short-term infusion of an average dose of propofol."7.75Hyperkalemia during surgery: is it an early warning of propofol infusion syndrome? ( Mali, AR; Mistry, RC; Patil, VP; Pramesh, CS, 2009)
"Interruption of sedation due to a poor response to modified neuroleptanalgesia (m-NLA) with midazolam often occurs during endoscopic submucosal dissection (ESD) for esophageal squamous cell carcinoma (ESCC) because most patients have a history of heavy alcohol intake."5.27Comparison of propofol with midazolam in endoscopic submucosal dissection for esophageal squamous cell carcinoma: a randomized controlled trial. ( Arakawa, T; Fujiwara, Y; Fukunaga, S; Kamata, N; Kato, K; Machida, H; Maruyama, H; Minamino, H; Nagami, Y; Ominami, M; Sakai, T; Shiba, M; Sugimori, S; Tanaka, F; Tanigawa, T; Tominaga, K; Watanabe, T; Yamagami, H, 2018)
"BACKGROUND This study was done to verify whether propofol could inhibit esophageal squamous cell carcinoma (ESCC) cell line EC9706 cell migration and invasion by targeting SOX4."3.85Propofol Suppresses Esophageal Squamous Cell Carcinoma Cell Migration and Invasion by Down-Regulation of Sex-Determining Region Y-box 4 (SOX4). ( Ji, P; Li, JJ; Zhou, CL, 2017)
"We present a case of severe hyperkalemia in a 48-year-old man after short-term infusion of an average dose of propofol."3.75Hyperkalemia during surgery: is it an early warning of propofol infusion syndrome? ( Mali, AR; Mistry, RC; Patil, VP; Pramesh, CS, 2009)
"Patients with superficial esophageal cancers who underwent esophageal endoscopic submucosal dissection at Yokohama City University Hospital were prospectively enrolled and were randomly assigned to the propofol and the propofol plus dexmedetomidine groups."3.01Efficacy of sedation with dexmedetomidine plus propofol during esophageal endoscopic submucosal dissection. ( Arimoto, J; Ashikari, K; Chiba, H; Fuyuki, A; Higurashi, T; Kanoshima, K; Matsuura, T; Misawa, N; Nakajima, A; Nonaka, T; Ohkubo, H; Takatsu, T; Yoshihara, T, 2021)
"Propofol is a pharmaceutical agent commonly used as an intravenous anesthetic in surgical treatments and a sedative in intensive care."1.91Propofol elicits apoptosis and attenuates cell growth in esophageal cancer cell lines. ( Konishi, Y; Nishiwaki, K; Zhang, A; Zhou, R, 2023)
"Propofol has been reported to be related to the migration, invasion, and epithelial-mesenchymal transition (EMT) of esophageal cancer (EC) cells."1.56Propofol suppresses hypoxia-induced esophageal cancer cell migration, invasion, and EMT through regulating lncRNA TMPO-AS1/miR-498 axis. ( Gao, M; Guo, R; Lu, X; Luo, S; Xu, G, 2020)
"Propofol-based sedation without endotracheal intubation is safe for ESD procedures in the esophagus and stomach with low anesthesia-related complication rates and short hospital stay."1.51Propofol sedation without endotracheal intubation is safe for endoscopic submucosal dissection in the esophagus and stomach. ( Bruno, MJ; Hilkemeijer, T; Klimek, M; Koch, AD; Leliveld, L; van de Ven, S, 2019)
" MAC did not cause any adverse effects requiring prolongation of hospitalization."1.42Safety and effectiveness of propofol-based monitored anesthesia care without intubation during endoscopic submucosal dissection for early gastric and esophageal cancers. ( Abe, S; Kawaguchi, Y; Kinjo, Y; Nakamura, J; Nonaka, S; Oda, I; Saito, Y; Sato, C; Sato, T; Suzuki, H; Yoshinaga, S, 2015)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.35)18.2507
2000's5 (21.74)29.6817
2010's14 (60.87)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Zhou, R1
Konishi, Y1
Zhang, A1
Nishiwaki, K1
Gao, M1
Guo, R1
Lu, X1
Xu, G1
Luo, S1
Ashikari, K1
Nonaka, T1
Higurashi, T1
Takatsu, T1
Yoshihara, T1
Misawa, N1
Arimoto, J1
Kanoshima, K1
Matsuura, T1
Fuyuki, A1
Ohkubo, H1
Chiba, H1
Nakajima, A1
Ominami, M1
Nagami, Y1
Shiba, M1
Tominaga, K1
Sakai, T1
Maruyama, H1
Kato, K1
Minamino, H1
Fukunaga, S1
Tanaka, F1
Sugimori, S1
Kamata, N1
Machida, H1
Yamagami, H1
Tanigawa, T1
Watanabe, T1
Fujiwara, Y1
Arakawa, T1
Zhang, GH1
Wang, W1
van de Ven, S1
Leliveld, L1
Klimek, M1
Hilkemeijer, T1
Bruno, MJ1
Koch, AD1
Xu, YB2
Du, QH1
Zhang, MY1
Yun, P1
He, CY1
Zhao, X2
Jin, YW1
Li, HB1
Wang, ZG1
Feng, H2
Feng, C1
Guo, JR1
Guo, W1
Jin, XJ1
Yu, J1
Jin, BW1
Xu, F1
Liu, Y1
Nonaka, S1
Kawaguchi, Y1
Oda, I1
Nakamura, J1
Sato, C1
Kinjo, Y1
Abe, S1
Suzuki, H1
Yoshinaga, S1
Sato, T1
Saito, Y1
Qiao, Y1
Zhao, T1
Yan, H1
Zhang, H1
Guo, XG1
Wang, S1
Zhuang, J1
Zhou, CL1
Li, JJ1
Ji, P1
Mali, AR1
Patil, VP1
Pramesh, CS1
Mistry, RC1
Zhang, LM1
Zhang, MX1
Wang, N1
Duan, XY1
Zhou, SN1
Wang, JS1
Jing, GX1
Song, JG1
Shin, JW1
Lee, EH1
Choi, DK1
Bang, JY1
Chin, JH1
Choi, IC1
Liu, HL1
Zhang, Y1
Zheng, GL1
Rong, QH1
Zhao, GL1
Xie, JP1
Wang, LX1
Hanazaki, M1
Taga, N1
Nakatsuka, H1
Yokoyama, M1
Morita, K1
Shirakawa, Y1
Yamatsuji, T1
Naomoto, Y1
Hiraki, T1
Abe, K1
Shimizu, T1
Takashina, M1
Shiozaki, H1
Yoshiya, I1
Wong, AY1
Lawmin, JC1
Irwin, MG1
Fujiwara, C1
Hirose, Y1
Gamo, M1
Harigae, M1
Matsuo, K1
Puebla, G1
Boimorto, R1
de la Calle, JL1
de la Casa, R1
Igea, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Effects of Total Intravenous Anesthesia and Inhalation Anesthesia on Lymphocytes in Patients Undergoing Colorectal Cancer Resection and the Mechanism Involved: a Single-center, Randomized, Prospective Study[NCT03193710]260 participants (Anticipated)Observational2017-09-01Recruiting
A Randomized Pilot Clinical Trial of the Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction of Sevoflurane in Patient's Whit ARDS Secondary to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2)[NCT04998253]Early Phase 124 participants (Actual)Interventional2020-10-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

10 trials available for propofol and Cancer of Esophagus

ArticleYear
Efficacy of sedation with dexmedetomidine plus propofol during esophageal endoscopic submucosal dissection.
    Journal of gastroenterology and hepatology, 2021, Volume: 36, Issue:7

    Topics: Conscious Sedation; Dexmedetomidine; Endoscopic Mucosal Resection; Esophageal Neoplasms; Humans; Hyp

2021
Comparison of propofol with midazolam in endoscopic submucosal dissection for esophageal squamous cell carcinoma: a randomized controlled trial.
    Journal of gastroenterology, 2018, Volume: 53, Issue:3

    Topics: Aged; Alcohol Drinking; Anesthetics, Intravenous; Endoscopic Mucosal Resection; Esophageal Neoplasms

2018
Effects of maintaining intravenous infusion of remifentanil or propofol on anesthesia and palinesthesia during anesthesia and analepsia.
    Genetics and molecular research : GMR, 2014, Feb-13, Volume: 13, Issue:2

    Topics: Adult; Aged; Anesthesia; Esophageal Neoplasms; Female; Hemodynamics; Humans; Infusions, Intravenous;

2014
Effects of stellate ganglionic block on hemodynamic changes and intrapulmonary shunt in perioperative patients with esophageal cancer.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:24

    Topics: Aged; Anesthesia, General; Autonomic Nerve Block; Esophageal Neoplasms; Female; Hemodynamics; Humans

2014
Postoperative cognitive dysfunction after inhalational anesthesia in elderly patients undergoing major surgery: the influence of anesthetic technique, cerebral injury and systemic inflammation.
    BMC anesthesiology, 2015, Oct-23, Volume: 15

    Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Cognition Disorders; Double-Blind Method; E

2015
Incidence of post-thoracotomy pain: a comparison between total intravenous anaesthesia and inhalation anaesthesia.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2012, Volume: 41, Issue:5

    Topics: Acute Pain; Adolescent; Adult; Aged; Analgesics; Anesthesia, Inhalation; Anesthesia, Intravenous; An

2012
[Clinical observation of injection of dexmedetomidine in anaesthesia for esophageal cancer operation].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2011, Volume: 27, Issue:4

    Topics: Adjuvants, Anesthesia; Adult; Aged; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Dexmedetomid

2011
Feasibility and safety of endoscopic submucosal dissection of esophageal or gastric carcinomas under general anesthesia.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2013, Volume: 22, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Diazepam; Endoscopy, Gastrointestinal; Esophage

2013
Anesthetic management of radiofrequency ablation of mediastinal metastatic lymph nodes adjacent to the trachea.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:4

    Topics: Anesthesia, General; Anesthetics, Intravenous; Body Temperature; Catheter Ablation; Esophageal Neopl

2006
The effects of propofol, isoflurane, and sevoflurane on oxygenation and shunt fraction during one-lung ventilation.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:5

    Topics: Adult; Aged; Anesthetics, Inhalation; Esophageal Neoplasms; Female; Hemodynamics; Humans; Intraopera

1998

Other Studies

13 other studies available for propofol and Cancer of Esophagus

ArticleYear
Propofol elicits apoptosis and attenuates cell growth in esophageal cancer cell lines.
    Nagoya journal of medical science, 2023, Volume: 85, Issue:3

    Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Esophageal Neoplasms; Humans; Hypnotics

2023
Propofol suppresses hypoxia-induced esophageal cancer cell migration, invasion, and EMT through regulating lncRNA TMPO-AS1/miR-498 axis.
    Thoracic cancer, 2020, Volume: 11, Issue:9

    Topics: Cell Movement; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Female; Humans; Hypnotics an

2020
Effects of sevoflurane and propofol on the development of pneumonia after esophagectomy: a retrospective cohort study.
    BMC anesthesiology, 2017, Dec-04, Volume: 17, Issue:1

    Topics: Aged; Anesthetics, Inhalation; Cohort Studies; Esophageal Neoplasms; Esophagectomy; Female; Hospital

2017
Propofol sedation without endotracheal intubation is safe for endoscopic submucosal dissection in the esophagus and stomach.
    United European gastroenterology journal, 2019, Volume: 7, Issue:3

    Topics: Aged; Analgesics, Opioid; Anesthetics, Intravenous; Cough; Endoscopic Mucosal Resection; Esophageal

2019
Propofol suppresses proliferation, invasion and angiogenesis by down-regulating ERK-VEGF/MMP-9 signaling in Eca-109 esophageal squamous cell carcinoma cells.
    European review for medical and pharmacological sciences, 2013, Volume: 17, Issue:18

    Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Esophageal Neoplasm

2013
Safety and effectiveness of propofol-based monitored anesthesia care without intubation during endoscopic submucosal dissection for early gastric and esophageal cancers.
    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2015, Volume: 27, Issue:6

    Topics: Aged; Case-Control Studies; Deep Sedation; Dissection; Early Detection of Cancer; Esophageal Neoplas

2015
Propofol suppresses invasion, angiogenesis and survival of EC-1 cells in vitro by regulation of S100A4 expression.
    European review for medical and pharmacological sciences, 2015, Volume: 19, Issue:24

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Dose-Response Relation

2015
Propofol Suppresses Esophageal Squamous Cell Carcinoma Cell Migration and Invasion by Down-Regulation of Sex-Determining Region Y-box 4 (SOX4).
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Jan-24, Volume: 23

    Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Esop

2017
Hyperkalemia during surgery: is it an early warning of propofol infusion syndrome?
    Journal of anesthesia, 2009, Volume: 23, Issue:3

    Topics: Analgesia, Epidural; Anesthesia, General; Anesthetics, Intravenous; Dose-Response Relationship, Drug

2009
[Effect of low dose propofol on biological behavior of esophageal squamous cell carcinoma cell line Eca109].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2011, Volume: 27, Issue:4

    Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Respo

2011
Anaesthetic management of a patient with low tracheal obstruction requiring placement of a T-Y stent.
    Anaesthesia and intensive care, 2000, Volume: 28, Issue:2

    Topics: Anesthesia; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Bronc

2000
[Anesthetic management for placement of tracheobronchial stents in patients with airway stenosis].
    Masui. The Japanese journal of anesthesiology, 2000, Volume: 49, Issue:5

    Topics: Adult; Aged; Anesthesia, Intravenous; Esophageal Neoplasms; Female; Fentanyl; Humans; Lung Neoplasms

2000
[Anesthesia in a case of Bardet-Biedl syndrome].
    Revista espanola de anestesiologia y reanimacion, 2001, Volume: 48, Issue:2

    Topics: Adenocarcinoma; Adult; Anesthesia; Anesthetics; Bardet-Biedl Syndrome; Esophageal Neoplasms; Esophag

2001