Page last updated: 2024-10-15

ed 110

Description

ED 110: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	135705573
MeSH ID	M0211303

Synonyms (10)

Synonym
139112-73-5
ed 110
j-109384
5h-indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6h)-dione, 12,13-dihydro-1,11-dihydroxy-12-beta-d-glucopyranosyl-
12-beta-d-glucopyranosyl-12,13-dihydro-1,11-dihydroxy-5h-indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6h)-dione
12,13-dihydro-1,11-dihydroxy-12-beta-d-glucopyranosyl-5h-indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6h)-dione
j 109384
ed-110
1,5-anhydro-1-(7-hydroxy-1,3,10-trioxo-2,3,8,9,10,12-hexahydro-1h-indolo[2,3-a]pyrrolo[3,4-c]carbazol-9-yl)hexitol
DTXSID90930362

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	4 (66.67)	18.2507
2000's	1 (16.67)	29.6817
2010's	1 (16.67)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	6 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
pyrroles 1H-pyrrole : A tautomer of pyrrole that has the double bonds at positions 2 and 4.. pyrrole : A five-membered monocyclic heteroarene comprising one NH and four CH units which forms the parent compound of the pyrrole group of compounds. Its five-membered ring structure has three tautomers. A 'closed class'.. azole : Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen.	1.98	1	pyrrole; secondary amine
camptothecin NSC 100880: carboxylate (opened lactone) form of camptothecin; RN refers to (S)-isomer; structure given in first source	2	1	delta-lactone; pyranoindolizinoquinoline; quinoline alkaloid; tertiary alcohol	antineoplastic agent; EC 5.99.1.2 (DNA topoisomerase) inhibitor; genotoxin; plant metabolite
glucose, (beta-d)-isomer beta-D-glucose : D-Glucopyranose with beta configuration at the anomeric centre.. (1->4)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->4) linkages.. (1->3)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->3) linkages.	3.25	6	D-glucopyranose	epitope; mouse metabolite

Condition	Relationship Strength	Studies
Esophageal Squamous Cell Carcinoma A carcinoma that originates usually from cells on the surface of the middle and lower third of the ESOPHAGUS. Tumor cells exhibit typical squamous morphology and form large polypoid lesions. Mutations in RNF6, LZTS1, TGFBR2, DEC1, and WWOX1 genes are associated with this cancer.	2.08	1
Carcinoma, Epidermoid [description not available]	2.08	1
Cancer of Esophagus [description not available]	2.08	1
Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)	2.08	1
Esophageal Neoplasms Tumors or cancer of the ESOPHAGUS.	2.08	1
Experimental Leukemia [description not available]	1.98	1
Experimental Neoplasms [description not available]	1.98	1
Cancer of Stomach [description not available]	1.98	1
Fibrosarcoma A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)	1.98	1
Stomach Neoplasms Tumors or cancer of the STOMACH.	1.98	1
Leukemia P388 An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene.	2.38	2
Cancer of Ovary [description not available]	2	1
Cancer of Prostate [description not available]	2	1
Ovarian Neoplasms Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.	2	1
Prostatic Neoplasms Tumors or cancer of the PROSTATE.	2	1

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