n-nitrosomethyl-2-hydroxypropylamine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

N-nitrosomethyl-2-hydroxypropylamine: RN & N1 from CA Form Index; RN given refers to parent cpd without isomeric designation; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	107719
MeSH ID	M0090845

Synonyms (21)

Synonym
75411-83-5
n-nitrosomethyl-2-hydroxypropylamine
1-[methyl(nitroso)amino]propan-2-ol
nmhp
2-hydroxypropylmethylnitrosamine
2-propanol, 1-(methylnitrosoamino)-, (s)-
n-nitrosomethyl(2-hydroxypropyl)amine
brn 4955027
ccris 2015
2-propanol, 1-(methylnitrosoamino)-
n-(2-hydroxypropyl)-n-methylnitrous amide
AKOS006275495
methyl-2-hydroxypropylnitrosamine
70377-77-4
ccris 3213
unii-8es3ue4777
8es3ue4777 ,
bis(tertbutylcyclopentadienyl) tianium dichloride
DTXSID5021047
nitroso-methyl-2-hydroxypropylamine
1-(methylnitrosoamino)-2-propanol

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	6 (75.00)	18.7374
1990's	1 (12.50)	18.2507
2000's	1 (12.50)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.13

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.13 (24.57)
Research Supply Index	2.20 (2.92)
Research Growth Index	4.32 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.13)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	8 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
dimethylnitrosamine Dimethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties. It causes serious liver damage and is a hepatocarcinogen in rodents.	1.96	1	nitrosamine	geroprotector; mutagen
diisopropanolnitrosamine diisopropanolnitrosamine: experimental carcinogen. N,N-bis(2-hydroxypropyl)nitrosamine : A nitrosamine that is dipropylamine in which the hydrogen attached to the nitrogen has been replaced by a nitroso group. It is a genotoxic carcinogen, targeting the lung, liver, thyroid, and kidney.	2.65	3	diol; nitrosamine; secondary alcohol	carcinogenic agent
nitrosobis(2-oxopropyl)amine nitrosobis(2-oxopropyl)amine: structure. nitrosobis(2-oxopropyl)amine : A nitrosamine that is iminodiacetone that is substituted by a nitroso group at the N-atom. It induces pancreatic ductal adenocarcinomas in Syrian golden hamsters (other rodents are not susceptible).	2.36	2	ketone; nitrosamine	carcinogenic agent
n-nitroso(2-hydroxypropyl)(2-oxopropyl)amine N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine: structure	2.36	2
n-nitrosomethyl-2-oxopropylamine N-nitrosomethyl-2-oxopropylamine: RN & N1 from 9th CI Form Index; structure in first source	3.06	5
nadp [no description available]	2	1
nad NAD(1-) : An anionic form of nicotinamide adenine dinucleotide arising from deprotonation of the two OH groups of the diphosphate moiety.	2	1	organophosphate oxoanion	cofactor; human metabolite; hydrogen acceptor; Saccharomyces cerevisiae metabolite

Condition	Relationship Strength	Studies
Cancer of Esophagus [description not available]	1.96	1
Angiosarcoma [description not available]	1.96	1
Cancer of Liver [description not available]	1.96	1
Experimental Hepatoma [description not available]	2.37	2
Cancer of Lung [description not available]	2.66	3
Cancer of Nose [description not available]	2.88	4
Esophageal Neoplasms Tumors or cancer of the ESOPHAGUS.	1.96	1
Hemangiosarcoma A rare malignant neoplasm characterized by rapidly proliferating, extensively infiltrating, anaplastic cells derived from blood vessels and lining irregular blood-filled or lumpy spaces. (Stedman, 25th ed)	1.96	1
Liver Neoplasms Tumors or cancer of the LIVER.	1.96	1
Lung Neoplasms Tumors or cancer of the LUNG.	2.66	3
Carcinoma, Epidermoid [description not available]	1.97	1
Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)	1.97	1
Bladder Cancer [description not available]	1.97	1
Experimental Neoplasms [description not available]	2.37	2
Papilloma, Squamous Cell [description not available]	1.97	1
Urinary Bladder Neoplasms Tumors or cancer of the URINARY BLADDER.	1.97	1
Carcinoma, Transitional Cell A malignant neoplasm derived from TRANSITIONAL EPITHELIAL CELLS, occurring chiefly in the URINARY BLADDER; URETERS; or RENAL PELVIS.	1.97	1
Papilloma A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)	1.97	1
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	1.97	1
Cancer of Pancreas [description not available]	2.38	2
Pancreatic Neoplasms Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).	2.38	2

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