diphenhydramine has been researched along with Cancer of Esophagus in 2 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diphenhydramine was used because of its possible antiemetic properties and its ability to control acute dystonic reactions." | 2.66 | Improved control of cisplatin-induced emesis with high-dose metoclopramide and with combinations of metoclopramide, dexamethasone, and diphenhydramine. Results of consecutive trials in 255 patients. ( Bosl, GJ; Clark, RA; Gralla, RJ; Groshen, S; Kalman, LA; Kelsen, DP; Kris, MG; Reilly, LK; Tyson, LB, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meredith, R | 1 |
| Salter, M | 1 |
| Kim, R | 1 |
| Spencer, S | 1 |
| Weppelmann, B | 1 |
| Rodu, B | 1 |
| Smith, J | 1 |
| Lee, J | 1 |
| Kris, MG | 1 |
| Gralla, RJ | 1 |
| Tyson, LB | 1 |
| Clark, RA | 1 |
| Kelsen, DP | 1 |
| Reilly, LK | 1 |
| Groshen, S | 1 |
| Bosl, GJ | 1 |
| Kalman, LA | 1 |
2 trials available for diphenhydramine and Cancer of Esophagus
| Article | Year |
|---|---|
Sucralfate for radiation mucositis: results of a double-blind randomized trial.
Topics: Anti-Ulcer Agents; Diphenhydramine; Double-Blind Method; Drug Therapy, Combination; Esophageal Neopl | 1997 |
Improved control of cisplatin-induced emesis with high-dose metoclopramide and with combinations of metoclopramide, dexamethasone, and diphenhydramine. Results of consecutive trials in 255 patients.
Topics: Adult; Aged; Antiemetics; Cisplatin; Clinical Trials as Topic; Dexamethasone; Diphenhydramine; Drug | 1985 |