Page last updated: 2024-09-23

uroporphyrin i

Description

uroporphyrin I: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID72424
CHEMBL ID429013
CHEBI ID27484
SCHEMBL ID4327021
MeSH IDM0105311

Synonyms (25)

Synonym
3,8,13,18-tetrakis(carboxymethyl)-21h,23h-porphine-2,7,12,17-tetrapropanoic acid
3-[(5z,10z,14z,19z)-7,12,17-tris(2-carboxyethyl)-3,8,13,18-tetrakis(carboxymethyl)-21,23-dihydroporphyrin-2-yl]propanoic acid
2,7,12,17-porphinetetrapropionic acid
3,8,13,18-tetrakis(carboxymethyl)porphyrin-2,7,12,17-tetrapropionic acid
3,8,13,18-tetrakis(carboxymethyl)porphyrin-2,7,12,17-tetrapropanoic acid
CHEBI:27484
C05767
607-14-7
uroporphyrin i
CHEMBL429013
SCHEMBL4327021
21h,23h-porphine-2,7,12,17-tetrapropanoic acid, 3,8,13,18-tetrakis(carboxymethyl)-
7gca4yue1k ,
unii-7gca4yue1k
3,3',3'',3'''-(3,8,13,18-tetrakis-carboxymethyl-21h,23h-porphine-2,7,12,17-tetrayl)-tetrakis-propionate
3,3',3'',3'''-(3,8,13,18-tetrakis-carboxymethyl-porphyrin-2,7,12,17-tetrayl)-tetra-propionic acid
2,7,12,17-porphinetetrapropionate
3-[7,12,17-tris-(2-carboxy-ethyl)-3,8,13,18-tetrakis-carboxymethyl-22,24-dihydro-porphin-2-yl]-propionate
3,3',3'',3'''-(3,8,13,18-tetrakis-carboxymethyl-porphyrin-2,7,12,17-tetrayl)-tetra-propionate
3-[7,12,17-tris-(2-carboxy-ethyl)-3,8,13,18-tetrakis-carboxymethyl-22,24-dihydro-porphin-2-yl]-propionic acid
3,3',3'',3'''-(3,8,13,18-tetrakis-carboxymethyl-21h,23h-porphine-2,7,12,17-tetrayl)-tetrakis-propionic acid
3,8,13,18-tetrakis(carboxymethyl)porphyrin-2,7,12,17-tetrapropanoate
DTXSID90896979
3,3',3'',3'''-[3,8,13,18-tetrakis(carboxymethyl)porphyrin-2,7,12,17-tetrayl]tetrapropanoic acid
DTXSID80862284

Pathways (1)

uroporphyrin i is involved in 1 pathway(s), involving a total of 0 unique proteins and 466 unique compounds

PathwayProteinsCompounds
Biochemical pathways: part I0466

Bioassays (2)

Assay IDTitleYearJournalArticle
AID106898Inhibition of HIV-1 P24 production.1994Journal of medicinal chemistry, Apr-15, Volume: 37, Issue:8
Three-dimensional structure-activity analysis of a series of porphyrin derivatives with anti-HIV-1 activity targeted to the V3 loop of the gp120 envelope glycoprotein of the human immunodeficiency virus type 1.
AID104239Inhibition of HIV-1 P24 production.1994Journal of medicinal chemistry, Apr-15, Volume: 37, Issue:8
Three-dimensional structure-activity analysis of a series of porphyrin derivatives with anti-HIV-1 activity targeted to the V3 loop of the gp120 envelope glycoprotein of the human immunodeficiency virus type 1.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (56)

TimeframeStudies, This Drug (%)All Drugs %
pre-199025 (44.64)18.7374
1990's15 (26.79)18.2507
2000's12 (21.43)29.6817
2010's2 (3.57)24.3611
2020's2 (3.57)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies4 (7.02%)4.05%
Observational0 (0.00%)0.25%
Other53 (92.98%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research Highlights

Safety/Toxicity (1)

ArticleYear
Antioxidant inhibition of porphyrin-induced cellular phototoxicity.
Journal of photochemistry and photobiology. B, Biology, Dec-31, Volume: 65, Issue: 2-3
2001
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]