clonazepam has been researched along with Cancer of Esophagus in 2 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We used esophageal cancer cell lines and primary cell cultures of human esophageal cancers and evaluated (i) expression and localization of PBR; (ii) PBR-ligand-induced inhibition of cell growth; (iii) induction of apoptosis; and (iv) alterations in cell cycle." | 1.31 | Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human esophageal cancer cells. ( Barthel, B; Carayon, P; Faiss, S; Grabowski, P; Höpfner, M; Maaser, K; Scherübl, H; Sutter, AP; Zeitz, M, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kurkjian, N | 1 |
| Kurkjian, C | 1 |
| Pant, S | 1 |
| Tucker, P | 1 |
| Sutter, AP | 1 |
| Maaser, K | 1 |
| Höpfner, M | 1 |
| Barthel, B | 1 |
| Grabowski, P | 1 |
| Faiss, S | 1 |
| Carayon, P | 1 |
| Zeitz, M | 1 |
| Scherübl, H | 1 |
2 other studies available for clonazepam and Cancer of Esophagus
| Article | Year |
|---|---|
Psycho-oncology: a brief history and case study.
Topics: Antidepressive Agents, Second-Generation; Carcinoma, Squamous Cell; Citalopram; Clonazepam; Depressi | 2013 |
Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human esophageal cancer cells.
Topics: Aged; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Caspases; Cell Cycle; Cell Divisio | 2002 |