Compounds > n-ethyl-n-nitrosourethane
Page last updated: 2024-11-05

n-ethyl-n-nitrosourethane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID11977
SCHEMBL ID3499661
MeSH IDM0079513

Synonyms (49)

Synonym
unii-0roq23ij4f
0roq23ij4f ,
hsdb 7862
ethylester kyseliny n-ethyl-n-nitrosokarbaminove
614-95-9
nitroso-n-ethylurethane
nitrosoethylurethane
nsc 24890
nsc24890
n-ethyl-n-nitrosourethan
ethyl ethylnitrosocarbamate
ethyl nitrosourethan
aethylnitrosourethan
ethyl n-ethylnitrosocarbamate
ethylnitrosocarbamic acid ethyl ester
n-ethyl-n-nitrosourethane
wln: onn2&vo2
ethylnitrosocarbamic acid, ethyl ester
nsc-24890
ethyl n-ethyl-n-nitrosourethane
ethylnitrosourethane
n-nitroso-n-ethylurethan
n-ethyl-n-nitrosocarbamic acid, ethyl ester
nitrosoethylurethan
n-nitrosoethylurethane
n,n-nitrosoethylurethane
n-nitroso-n-ethylurethane
ethyl ethyl(nitroso)carbamate
aethylnitrosourethan [german]
ethyl nitrosourethane
n-ethyl-n-nitrosocarbamic acid ethyl ester
brn 1764259
ai3-16184
ethylnitrosourethan
carbamic acid, ethylnitroso-, ethyl ester
ccris 1376
ethylester kyseliny n-ethyl-n-nitrosokarbaminove [czech]
ethyl n-ethyl-n-nitroso-carbamate
ethyl n-ethyl-n-nitrosocarbamate
AKOS006272647
SCHEMBL3499661
carbamic acid, n-ethyl-n-nitroso-, ethyl ester
n-ethyl-n-nitrosourethane [hsdb]
RAUQLNDTFONODT-UHFFFAOYSA-N
ethyl 1-ethyl-2-oxohydrazinecarboxylate #
n-nitro-n-ethylurethane
DTXSID1021037
carbamic acid, ethylnitroso-ethyl ester
Q27237148

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
"A dose-response study on the carcinogenicity of N-ethyl-N-nitrosourethane (ENUR) was undertaken to examine its effect at low doses."( Dose-response carcinogenicity in rats on low-dose levels of N-ethyl-N-nitrosourethane.
Hayashi, Y; Kodama, Y; Maekawa, A; Matsushima, Y; Nagaoka, T; Onodera, H; Shibutani, M; Todate, A, 1989)		0.77
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (66.67)18.7374
1990's2 (22.22)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.79

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.79 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.09 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.79)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
urethane
[no description available]		2.6530carbamate esterfungal metabolite;
mutagen
nitrosomethylurethane
Nitrosomethylurethane: An alkylating carcinogen that produces gastrointestinal and probably lung and nervous system tumors.		3.5890carboxylic ester
methylnitrosourea
Methylnitrosourea: A nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.. N-methyl-N-nitrosourea : A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by methyl and nitroso groups.		2.3720N-nitrosoureasalkylating agent;
carcinogenic agent;
mutagen;
teratogenic agent
ethylnitrosourea
Ethylnitrosourea: A nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.. N-ethyl-N-nitrosourea : A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups.		2.3720N-nitrosoureasalkylating agent;
carcinogenic agent;
genotoxin;
mutagen
deuterium
Deuterium: The stable isotope of hydrogen. It has one neutron and one proton in the nucleus.		1.9610dihydrogen
1-o-hexyl-2,3,5-trimethylhydroquinone
[no description available]		1.9910
ConditionIndicatedRelationship StrengthStudiesTrials
Carcinoma, Anaplastic
[description not available]		02.3620
Cancer of Duodenum
[description not available]		02.3620
Cancer of Esophagus
[description not available]		02.6530
Cancer of Mouth
[description not available]		02.3620
Experimental Neoplasms
[description not available]		02.8840
Papilloma, Squamous Cell
[description not available]		02.6630
Cancer of Pharynx
[description not available]		02.3620
Cancer of Stomach
[description not available]		02.8840
Carcinoma
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.		02.3620
Esophageal Neoplasms
Tumors or cancer of the ESOPHAGUS.		02.6530
Mouth Neoplasms
Tumors or cancer of the MOUTH.		02.3620
Papilloma
A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)		02.6630
Pharyngeal Neoplasms
Tumors or cancer of the PHARYNX.		02.3620
Stomach Neoplasms
Tumors or cancer of the STOMACH.		02.8840
Cancer of Liver
[description not available]		01.9610
Liver Neoplasms
Tumors or cancer of the LIVER.		01.9610
Cancer of the Tongue
[description not available]		02.3720
Cocarcinogenesis
The combination of two or more different factors in the production of cancer.		01.9910
Hyperplasia
An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.		01.9910
Tongue Neoplasms
Tumors or cancer of the TONGUE.		02.3720
Abnormalities, Autosome
[description not available]		0210
Glial Cell Tumors
[description not available]		0210
Chromosome Deletion
Actual loss of portion of a chromosome.		0210
Glioma
Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)		0210
Cancer of Gastrointestinal Tract
[description not available]		01.9710