| Assay ID | Title | Year | Journal | Article |
|---|
| AID39592 | Compound was evaluated for the antineoplastic activity on B16 Melanoma cells at the optimal dose of 100 mg/kg through intraperitoneal route on days 1,5,9 | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| Synthesis and properties of bis(2,2-dimethylaziridinyl)phosphinic amides: a series of new antineoplastic agents. |
| AID121526 | effect of drug treatment in combination with gamma radiation on P-388 leukemia in mice at 120 mg/kg and 200R expressed as median survival time of drug treated mice/median survival time of control mice x100 | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4
| Synthesis of potential dual-acting radiation sensitizer antineoplastic agents: 2,2-dimethylphosphoraziridines containing 2-nitroimidazoles or other electron-affinic moieties. |
| AID153652 | Average weight change of mice was determined on day 6 after intraperitoneal injection on day 1 at a dose of 100 mg/kg following intraperitoneal implant of P388 leukemia cells in CDF1 mice | 1990 | Journal of medicinal chemistry, Sep, Volume: 33, Issue:9
| Synthesis of new nucleoside phosphoraziridines as potential site-directed antineoplastic agents. |
| AID111532 | effect of drug treatment in combination with gamma radiation on P-388 leukemia in mice at 120 mg/kg and 200R expressed as average weight change | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4
| Synthesis of potential dual-acting radiation sensitizer antineoplastic agents: 2,2-dimethylphosphoraziridines containing 2-nitroimidazoles or other electron-affinic moieties. |
| AID121528 | effect of drug treatment in combination with gamma radiation on P-388 leukemia in mice at 120 mg/kg and 600R expressed as median survival time of drug treated mice/median survival time of control mice x100 | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4
| Synthesis of potential dual-acting radiation sensitizer antineoplastic agents: 2,2-dimethylphosphoraziridines containing 2-nitroimidazoles or other electron-affinic moieties. |
| AID104038 | Antitumor activity against M109 implants through subcutaneous route along with the optimal dose of 100 mg/kg through intraperitoneal route on 1,4 days | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| Synthesis and properties of bis(2,2-dimethylaziridinyl)phosphinic amides: a series of new antineoplastic agents. |
| AID154110 | Antitumor activity was determined after intraperitoneal injection on day 1 at a dose of 200 mg/kg following intraperitoneal implant of P388 leukemia cells in CDF1 mice | 1990 | Journal of medicinal chemistry, Sep, Volume: 33, Issue:9
| Synthesis of new nucleoside phosphoraziridines as potential site-directed antineoplastic agents. |
| AID153654 | Average weight change of mice was determined on day 6 after intraperitoneal injection on day 1 at a dose of 200 mg/kg following intraperitoneal implant of P388 leukemia cells in CDF1 mice | 1990 | Journal of medicinal chemistry, Sep, Volume: 33, Issue:9
| Synthesis of new nucleoside phosphoraziridines as potential site-directed antineoplastic agents. |
| AID111222 | In vivo antitumor activity against P-388 leukemia in CDF1 mice at 100 mg or 430 umol by ip administration expressed as average wt. change determined between day 0 and day 6 of experiment | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4
| Synthesis of potential dual-acting radiation sensitizer antineoplastic agents: 2,2-dimethylphosphoraziridines containing 2-nitroimidazoles or other electron-affinic moieties. |
| AID111232 | In vivo antitumor activity against P-388 leukemia in CDF1 mice at 200 mg or 861 umol by ip administration expressed as average wt. change determined between day 0 and day 6 of experiment | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4
| Synthesis of potential dual-acting radiation sensitizer antineoplastic agents: 2,2-dimethylphosphoraziridines containing 2-nitroimidazoles or other electron-affinic moieties. |
| AID153459 | Compound was evaluated for the antineoplastic activity against P388 leukemia at an optimal dose of 80 mg/kg administered intraperitoneally | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| Synthesis and properties of bis(2,2-dimethylaziridinyl)phosphinic amides: a series of new antineoplastic agents. |
| AID154108 | Antitumor activity was determined after intraperitoneal injection on day 1 at a dose of 100 mg/kg following intraperitoneal implant of P388 leukemia cells in CDF1 mice | 1990 | Journal of medicinal chemistry, Sep, Volume: 33, Issue:9
| Synthesis of new nucleoside phosphoraziridines as potential site-directed antineoplastic agents. |
| AID111534 | effect of drug treatment in combination with gamma radiation on P-388 leukemia in mice at 120 mg/kg and 600R expressed as average weight change | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4
| Synthesis of potential dual-acting radiation sensitizer antineoplastic agents: 2,2-dimethylphosphoraziridines containing 2-nitroimidazoles or other electron-affinic moieties. |
| AID111533 | effect of drug treatment in combination with gamma radiation on P-388 leukemia in mice at 120 mg/kg and 400R expressed as average weight change | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4
| Synthesis of potential dual-acting radiation sensitizer antineoplastic agents: 2,2-dimethylphosphoraziridines containing 2-nitroimidazoles or other electron-affinic moieties. |
| AID120816 | Tumor free mice out of 6 surviving to day 30 or beyond was determined | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| Synthesis and properties of bis(2,2-dimethylaziridinyl)phosphinic amides: a series of new antineoplastic agents. |
| AID121655 | In vivo antitumor activity against P-388 leukemia in CDF1 mice at 100 mg or 430 umol by ip administration expressed as median survival time of drug treated mice/median survival time of control mice x100 | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4
| Synthesis of potential dual-acting radiation sensitizer antineoplastic agents: 2,2-dimethylphosphoraziridines containing 2-nitroimidazoles or other electron-affinic moieties. |
| AID121527 | effect of drug treatment in combination with gamma radiation on P-388 leukemia in mice at 120 mg/kg and 400R expressed as median survival time of drug treated mice/median survival time of control mice x100 | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4
| Synthesis of potential dual-acting radiation sensitizer antineoplastic agents: 2,2-dimethylphosphoraziridines containing 2-nitroimidazoles or other electron-affinic moieties. |
| AID104037 | Antitumor activity against M109 implants through intraperitoneal route along with the optimal dose of 150 mg/kg through intraperitoneal route on 1,4 days | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| Synthesis and properties of bis(2,2-dimethylaziridinyl)phosphinic amides: a series of new antineoplastic agents. |
| AID111531 | effect of drug treatment in combination with gamma radiation on P-388 leukemia in mice at 120 mg/kg and 0R expressed as average weight change | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4
| Synthesis of potential dual-acting radiation sensitizer antineoplastic agents: 2,2-dimethylphosphoraziridines containing 2-nitroimidazoles or other electron-affinic moieties. |
| AID43046 | Antitumor activity against C26 implants through intraperitoneal route along with the optimal dose of 120 mg/kg through intraperitoneal injection on 5,8 days | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| Synthesis and properties of bis(2,2-dimethylaziridinyl)phosphinic amides: a series of new antineoplastic agents. |
| AID121525 | effect of drug treatment in combination with gamma radiation on P-388 leukemia in mice at 120 mg/kg and 0R expressed as median survival time of drug treated mice/median survival time of control mice x100 | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4
| Synthesis of potential dual-acting radiation sensitizer antineoplastic agents: 2,2-dimethylphosphoraziridines containing 2-nitroimidazoles or other electron-affinic moieties. |
| AID121791 | In vivo antitumor activity against P-388 leukemia in CDF1 mice at 200 mg or 861 umol by ip administration expressed as median survival time of drug treated mice/median survival time of control mice x100 | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4
| Synthesis of potential dual-acting radiation sensitizer antineoplastic agents: 2,2-dimethylphosphoraziridines containing 2-nitroimidazoles or other electron-affinic moieties. |
| AID43165 | Antitumor activity against C26 implants through subcutaneous route along with the optimal dose of 120 mg/kg through intraperitoneal injection on 5,8 days | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| Synthesis and properties of bis(2,2-dimethylaziridinyl)phosphinic amides: a series of new antineoplastic agents. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |