Page last updated: 2024-10-24

verapamil and Cancer of Esophagus

verapamil has been researched along with Cancer of Esophagus in 4 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
"This study aimed to investigate the reversal effect of verapamil (VER) on the chemoresistance to cisplatin of esophageal squamous cell carcinoma (ESCC) cells."8.02Upregulation of KCNMA1 facilitates the reversal effect of verapamil on the chemoresistance to cisplatin of esophageal squamous cell carcinoma cells. ( Chang, N; Fan, PS; Ge, N; Kang, YH; Yang, GS; Zhang, TY; Zhou, Q, 2021)
"This study aimed to investigate the reversal effect of verapamil (VER) on the chemoresistance to cisplatin of esophageal squamous cell carcinoma (ESCC) cells."4.02Upregulation of KCNMA1 facilitates the reversal effect of verapamil on the chemoresistance to cisplatin of esophageal squamous cell carcinoma cells. ( Chang, N; Fan, PS; Ge, N; Kang, YH; Yang, GS; Zhang, TY; Zhou, Q, 2021)
"Verapamil has been shown to reverse acquired drug resistance to Adriamycin (ADR) and vinblastine in the P388 leukemia and Ehrlich ascites carcinoma model systems."1.27Effect of verapamil on in vitro cytotoxicity of adriamycin and vinblastine in human tumor cells. ( Cox, TC; Crowley, J; Goodman, GE; Yen, YP, 1987)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Ge, N1
Yang, GS1
Zhang, TY1
Chang, N1
Kang, YH1
Zhou, Q1
Fan, PS1
Wang, Y1
Chen, Q1
Jin, S1
Deng, W1
Li, S1
Tong, Q1
Chen, Y1
Haorah, J1
Miller, DW1
Brand, R1
Smyrk, TC1
Wang, X1
Chen, SC1
Mirvish, SS1
Goodman, GE1
Yen, YP1
Cox, TC1
Crowley, J1

Other Studies

4 other studies available for verapamil and Cancer of Esophagus

ArticleYear
Upregulation of KCNMA1 facilitates the reversal effect of verapamil on the chemoresistance to cisplatin of esophageal squamous cell carcinoma cells.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cell Survival; Cisplatin; Drug Re

2021
Up-regulation of P-glycoprotein is involved in the increased paclitaxel resistance in human esophageal cancer radioresistant cells.
    Scandinavian journal of gastroenterology, 2012, Volume: 47, Issue:7

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Ci

2012
Diffusion of dialkylnitrosamines into the rat esophagus as a factor in esophageal carcinogenesis.
    Carcinogenesis, 1999, Volume: 20, Issue:5

    Topics: Animals; Calcium Channel Blockers; Carcinogens; Central Nervous System Depressants; Diffusion; Enzym

1999
Effect of verapamil on in vitro cytotoxicity of adriamycin and vinblastine in human tumor cells.
    Cancer research, 1987, May-01, Volume: 47, Issue:9

    Topics: Breast Neoplasms; Cell Survival; Clone Cells; Colonic Neoplasms; Doxorubicin; Drug Resistance; Esoph

1987