Page last updated: 2024-11-12

ctce-9908

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

CTCE-9908: antineoplastic; a small peptide CXCR4 antagonist [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID16186350
CHEMBL ID3544949
MeSH IDM0535319

Synonyms (7)

Synonym
l-lysinamide, n2,n6-bis(l-lysylglycyl-l-valyl-l-seryl-l-leucyl-l-seryl-l-tyrosyl-l-arginyl)-
nf0bx95a31 ,
unii-nf0bx95a31
ctce-9908
ptx-9908 free base
CHEMBL3544949
Q27284835

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" We first performed a dosing experiment of CTCE-9908 in the PyMT mouse model, testing 25, 50 and 100 mg/kg versus the scrambled peptide in groups of 8-16 mice."( CXCR4 peptide antagonist inhibits primary breast tumor growth, metastasis and enhances the efficacy of anti-VEGF treatment or docetaxel in a transgenic mouse model.
Aguilar-Mahecha, A; Alsawafi, Y; Basik, M; Buchanan, M; Gaboury, L; Hassan, S; Jahan, K; Mourskaia, AA; Muller, WJ; Salvucci, O; Siegel, PM, 2011
)
0.63
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (17)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (35.29)29.6817
2010's10 (58.82)24.3611
2020's1 (5.88)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 19.25

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index19.25 (24.57)
Research Supply Index3.00 (2.92)
Research Growth Index4.61 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (19.25)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (5.56%)5.53%
Reviews3 (16.67%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other14 (77.78%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]