Compounds > n'-nitrosoanabasine
Page last updated: 2024-11-05

n'-nitrosoanabasine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

N'-nitrosoanabasine: structure; RN given refers to cpd without isomeric designation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID14335
CHEBI ID82507
SCHEMBL ID4538641
MeSH IDM0055623

Synonyms (38)

Synonym
3-(1-nitrosopiperidin-2-yl)pyridine
nitrosoanabasine
n'-nitrosoanabasine
(+-)-1-nitrosoanabasine
pyridine, 3-(1-nitroso-2-piperidinyl)-, (+-)-
(+-)-3-(1-nitroso-2-piperidinyl)pyridine
(+-)-n-nitrosoanabasine
37620-20-5
AKOS006283714
3-(1-nitroso-2-piperidinyl)-pyridine
C19477
pyridine, 3-(1-nitroso-2-piperidinyl)-
y7vu5e9xat ,
unii-y7vu5e9xat
3-(1-nitroso-2-piperidinyl)pyridine
84237-39-8
FT-0672937
FT-0672938
FT-0672936
1-nitroso-2-(3-pyridyl)piperidine
(r,s)-n-nitroso anabasine
CHEBI:82507
SCHEMBL4538641
DTXSID3021019
n-nitrosoanabasine, analytical standard
AS-61613
Z1198156221
pyridine, 3-(1-nitroso-2-piperidinyl)-; piperidine, 1-nitroso-2-(3-pyridyl)- (6ci,7ci); 3-(1-nitroso-2-piperidinyl)pyridine; (r,s)-n-nitroso anabasine; (rs)-n-nitrosoanabasine
Q27156016
n-nitrosoanabasine 100 microg/ml in acetonitrile
STL570268
piperidine, 1-nitroso-2-(3-pyridyl)-
(s)-n-nitroso anabasine, > 98% ee
(s)-n-nitroso anabasine, > 70% ee
n-nitrosoanabasine, (rs)-
n-nitrosoanabasine, (+/-)-
PD159715
EN300-8589027
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
citraconoyl group
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (17)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (17.65)18.7374
1990's5 (29.41)18.2507
2000's2 (11.76)29.6817
2010's4 (23.53)24.3611
2020's3 (17.65)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 19.62

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index19.62 (24.57)
Research Supply Index2.94 (2.92)
Research Growth Index4.93 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (19.62)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other18 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
nornicotine
nornicotine: agricultural or horticultural insecticide; RN given refers to (+-)-isomer; structure		2.5220
4-nitrosodimethylaniline
4-nitrosodimethylaniline: structure; RN given refers to parent cpd. N,N-dimethyl-4-nitrosoaniline : A member of the class of dimethylanilines that is N,N-dimethylaniline having a nitroso group at the 4-position.		1.9910dimethylaniline;
nitroso compound;
tertiary amino compound
n'-nitrosonornicotine
N'-nitrosonornicotine: structure; a potent carcinogen in laboratory animals		4.09150pyridines;
pyrrolidines
4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone: structure; from tobacco smoke		3.5180nitrosamine;
pyridines
nicotine
(S)-nicotine : A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum.		3.52803-(1-methylpyrrolidin-2-yl)pyridineanxiolytic drug;
biomarker;
immunomodulator;
mitogen;
neurotoxin;
nicotinic acetylcholine receptor agonist;
peripheral nervous system drug;
phytogenic insecticide;
plant metabolite;
psychotropic drug;
teratogenic agent;
xenobiotic
glucuronic acid
Glucuronic Acid: A sugar acid formed by the oxidation of the C-6 carbon of GLUCOSE. In addition to being a key intermediate metabolite of the uronic acid pathway, glucuronic acid also plays a role in the detoxification of certain drugs and toxins by conjugating with them to form GLUCURONIDES.. D-glucuronic acid : The D-enantiomer of glucuronic acid.. D-glucopyranuronic acid : A D-glucuronic acid in cyclic pyranose form.		1.9810D-glucuronic acidalgal metabolite
4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol
4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol: structure in first source. 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol : A member of the class of nitrosamines that is butan-1-ol substituted by a pyridin-3-yl group at position 1 and by a methyl(nitroso)amino group at position 4. It is a major metabolite of nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), which is a carcinogen found in tobacco and responsible for inducing lung cancer in smokers.		2.830nitrosamine;
pyridines;
secondary alcohol		biomarker;
carcinogenic agent;
human urinary metabolite
4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol
4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol: tobacco-specific N-nitrosamine; structure given in first source		1.9810
4-hydoxy-1-(3-pyridyl)-1-butanone
4-hydoxy-1-(3-pyridyl)-1-butanone: structure given in first source; may be metabolic product of tobacco-specific nitrosamines		2.1310aromatic ketone
hydroxycotinine
hydroxycotinine: metabolite of nicotine; RN given refers to (S)-isomer; structure. trans-3-hydroxycotinine : An N-alkylpyrrolidine that is cotinine substituted at position C-3 by a hydroxy group (the 3R,5S-diastereomer).		1.9810N-alkylpyrrolidine;
pyridines;
pyrrolidin-2-ones;
pyrrolidine alkaloid
cotinine-n-oxide
cotinine-N-oxide: metabolite of nicotine; structure		1.9810
anabasine
Anabasine: A piperidine botanical insecticide.. (S)-anabasine : The (S)-enantiomer of anabasine.. anabasine : A pyridine alkaloid that is pyridine substituted by a piperidin-2-yl group at position 3.		7.3720anabasine
n'-nitrosoanatabine
N'-nitrosoanatabine: nitroso cpd prepared from alkaloid anatabine; structure given in first source		8.82110
cotinine
Cotinine: The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It has CNS stimulating properties.. (-)-cotinine : An N-alkylpyrrolidine that consists of N-methylpyrrolidinone bearing a pyridin-3-yl substituent at position C-5 (the 5S-enantiomer). It is an alkaloid commonly found in Nicotiana tabacum.		1.9810N-alkylpyrrolidine;
pyridines;
pyrrolidin-2-ones;
pyrrolidine alkaloid		antidepressant;
biomarker;
human xenobiotic metabolite;
plant metabolite
piperidines
Piperidines: A family of hexahydropyridines.		1.9510
concanavalin a
Concanavalin A: A MANNOSE/GLUCOSE binding lectin isolated from the jack bean (Canavalia ensiformis). It is a potent mitogen used to stimulate cell proliferation in lymphocytes, primarily T-lymphocyte, cultures.		1.9910
ConditionIndicatedRelationship StrengthStudiesTrials
Cancer of Esophagus
[description not available]		02.3720
Experimental Neoplasms
[description not available]		02.3620
Esophageal Neoplasms
Tumors or cancer of the ESOPHAGUS.		02.3720
Mouth Diseases
Diseases involving the MOUTH.		01.9810
Leukoedema, Oral
A disorder of the buccal mucosa resembling early leukoplakia, characterized by the presence of filmy opalescence of the mucosa in the early stages to a whitish gray cast with a coarsely wrinkled surface in the later stages, associated with intracellular edema of the spinous or malpighian layer. (Dorland, 27th ed)		01.9810
Cancer of Nose
[description not available]		01.9510
Tracheal Neoplasms
New abnormal growth of tissue in the TRACHEA.		01.9510
Papilloma, Squamous Cell
[description not available]		01.9610
Papilloma
A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)		01.9610