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diethylnitrosamine and Cancer of Esophagus

diethylnitrosamine has been researched along with Cancer of Esophagus in 55 studies

Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.

Research Excerpts

ExcerptRelevanceReference
" Two types of areas composed of basophilic or glycogenotic hepatocytes were observed preceding the appearance of hepatocellular adenomas and carcinomas."3.68Rat hepatocarcinogenesis induced by N-nitrosodiethylamine and N-nitrosomorpholine continuously administered at low doses. From basophilic areas of hepatocytes to hepatocellular tumors. ( Cortinovis, C; Klimek, F; Nogueira, E, 1991)
" Diethylnitrosamine (DEN) when given in drinking water at the dose of 4 mg/kg body weight/day, induced esophageal papillomas consistently in 100% of the animals, in a short period of 12 weeks."3.67ICRC mouse with congenital mega-esophagus as a model to study esophageal tumorigenesis. ( Deo, MG; Ghaisas, S; Saranath, D, 1989)
"Carcinomas developed in the mucosa of the esophagus in BUF strain rats ingesting diethylnitrosamine in the diet."3.65Histopathology of preneoplastic and neoplastic lesions of the esophagus in BUF rats ingesting diethylnitrosamine. ( Reuber, MD, 1977)
" However, they were unable to predict the shape of the dose-response curve at low doses."1.32Threshold for carcinogenicity of N-nitrosodiethylamine for esophageal tumors in rats. ( Waddell, WJ, 2003)
"Annual standardized mortality rates of esophageal cancer in Nan'ao and Lufeng are 110/10(6) and 10/10(6) respectively."1.31Dietary exposure and urinary excretion of total N-nitroso compounds, nitrosamino acids and volatile nitrosamine in inhabitants of high- and low-risk areas for esophageal cancer in southern China. ( Lin, K; Lu, S; Shen, W; Shen, Z; Wu, Y, 2002)
" This research confirms the effectiveness of the DEN in bringing about carcinogenesis in the Wistar rat esophagus and also shows that the lesions are dosage dependent."1.31Experimental esophageal carcinogenesis: technical standardization and results. ( Andreollo, NA; Eshkenazy, R; Pajecki, D; Sallet, JA; Zilberstein, B, 2002)
"Diethylnitrosamine (DEN) is a carcinogen that stimulates the development of epidermoid carcinoma in the esophagus of mice."1.30Influence of surgically induced gastric and gastroduodenal content reflux on esophageal carcinogenesis--experimental model in Wistar female rats. ( Boeno, Rda L; Cavazzola, LT; Grossi, RS; Kliemann, LM; Kruel, CD; Melo, LL; Silber, PC, 1999)
"Diethylnitrosamine was administered in the drinking water for 18 weeks."1.29Interferon-alpha/beta can impede development of carcinogen-induced squamous-cell tumors in the esophagus of C57B1 mice. ( Fagerberg, J; Gresser, I; Kuylenstierna, R; Munck-Wikland, E; Rubio, C; Strander, H, 1995)
" The principal aim was to characterize the dose-response relationship for the effects of these agents on esophageal cancer (NDEA) or on various types of liver cancer (NDEA and NDMA), although NDEA also caused a few tumors of the nasopharynx and NDMA also caused a few tumors of the lung."1.28Effects on 4080 rats of chronic ingestion of N-nitrosodiethylamine or N-nitrosodimethylamine: a detailed dose-response study. ( Brantom, P; Grasso, P; Gray, R; Peto, R, 1991)
" Studies of 16 different concentrations of N-nitrosopyrrolidine and N-nitrosopiperidine given from age 6 weeks onwards to small groups of rats yielded dose-response relationships for the effects of N-nitrosopyrrolidine on liver tumors and for those of N-nitrosopiperidine on tumors of the liver and upper gastrointestinal tract that resembled those seen for NDMA and NDEA, respectively, except that N-nitrosopyrrolidine and N-nitrosopiperidine were less potent [the respective dose rates needed to halve the proportion of tumorless survivors after 2 years of treatment being approximately 0."1.28Chronic nitrosamine ingestion in 1040 rodents: the effect of the choice of nitrosamine, the species studied, and the age of starting exposure. ( Brantom, P; Grasso, P; Gray, R; Peto, R, 1991)
" The dose levels in the individual dose-response experiments ranged from the lowest concentrations of previous experiments (NDEA, 0."1.27Combination experiments with very low doses of three genotoxic N-nitrosamines with similar organotropic carcinogenicity in rats. ( Berger, MR; Schmähl, D; Zerban, H, 1987)
"Methionine was contained in both the amino acid and the lipotrope supplement and probably was responsible for reducing hepatocarcinoma incidence."1.26Reduction of N-nitrosodiethylamine carcinogenesis in rats by lipotrope or amino acid supplementation of a marginally deficient diet. ( Rogers, AE, 1977)
" DENA, which was administered to 38 rats in a dosage of 20 mg/kg/week, induced liver tumors in 90% of the animals; in 29% besides some precancerous stages predominantly malignant carcinomas of the oesophagus were seen."1.26Influence of disulfiram on the organotropy of the carcinogenic effect of dimethylnitrosamine and diethylnitrosamine in rats. ( Diehl, B; Habs, M; Krüger, FW; Schmähl, D, 1976)
"After the gavage of 200 mg N-nitrosodiethylamine per kg body weight only kidney tumors developed while long-term administration of 10 ppm N-nitrosodiethylamine induced esophageal tumors and hepatocellular carcinomas in female rats (SIV 50)."1.26[Comparative investigations on the organotropic carcinogenic effect of different N-nitroso compounds with rat after single and chronic treatment (author's transl)]. ( Kouros, M; Manncke, K; Schweinsberg, F, 1979)
" DMN induced a considerable quantity of liver tumours, the highest incidence being demonstrated in the lowest dosage group."1.26Carcinogenic effects of different nitroso-compounds in Chinese hamsters. I. Dimethylnitrosamine and N-diethylnitrosamine. ( Kmoch, N; Mohr, U; Reznik, G, 1976)

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199030 (54.55)18.7374
1990's13 (23.64)18.2507
2000's10 (18.18)29.6817
2010's2 (3.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Visoni, S1
Lang, M1
Ribeiro Pinto, LF1
Silva, JF1
Bidinotto, LT1
Furtado, KS1
Salvadori, DM1
Rivelli, DP1
Barros, SB1
Rodrigues, MA1
Barbisan, LF1
Kruel, CR2
Pinto, LF1
Blanco, TC1
Barja-Fidalgo, TC1
Melo, LL2
Kruel, CD4
de Castro Junior, MA1
Meurer, L1
de Castro, AP1
Myburg, RB1
Dutton, MF1
Chuturgoon, AA1
Lin, K1
Shen, W1
Shen, Z1
Wu, Y1
Lu, S1
Sallet, JA1
Zilberstein, B1
Andreollo, NA1
Eshkenazy, R1
Pajecki, D1
Waddell, WJ1
DRUCKREY, H1
SCHILDBACH, A1
SCHMAEHL, D1
PREUSSMANN, R1
IVANKOVIC, S1
Zgodziński, W1
Zinkiewicz, K1
Juśkiewicz, W1
Szumiło, J1
Wallner, G1
Bolieva, LZ1
Dzhioev, FK1
Kakabadze, SA1
Mandard, AM1
Marnay, J1
Herlin, P1
Elie, H1
Tuyns, AJ1
Le Talaer, JY1
Swann, PF1
Rubio, CA4
Jiao, BZ1
Lijinsky, W4
Habs, M2
Schmähl, D4
Reuber, MD4
Fagerberg, J1
Rubio, C1
Gresser, I1
Kuylenstierna, R1
Munck-Wikland, E1
Strander, H1
Chu, JJ1
Xu, YC1
Ye, BF1
Balansky, RM2
Blagoeva, PM1
Mircheva, ZI1
De Flora, S2
Aze, Y1
Toyoda, K1
Furukawa, F1
Mitsumori, K1
Takahashi, M1
Kishimoto, T1
Kokura, K1
Ohkawa, N1
Makino, Y1
Yoshida, M1
Hirohashi, S1
Niwa, S1
Muramatsu, M1
Tamura, T1
Gurski, RR1
Schirmer, CC1
Komlos, F1
Edelweiss, MI1
Kliemann, LM1
Cavazzola, LT1
Boeno, Rda L1
Silber, PC1
Grossi, RS1
Ganchev, G1
D'Agostini, F1
Mori, Y1
Koide, A1
Kobayashi, Y1
Morimura, K1
Kaneko, M1
Fukushima, S1
Gurkalo, VK1
Zabezhinskiĭ, MA1
Rogers, AE2
Krüger, FW1
Diehl, B1
Taylor, HW2
Walker, EA1
Castegnaro, M1
Garren, L1
Toussaint, G1
Kowalski, B1
Schweinsberg, F1
Kouros, M1
Manncke, K1
Wishnok, JS1
Archer, MC1
Reznik, G1
Mohr, U1
Kmoch, N1
Ji, C1
Li, M1
Peto, R3
Gray, R3
Brantom, P3
Grasso, P3
Cortinovis, C1
Klimek, F1
Nogueira, E1
Mufti, SI1
Ghaisas, S1
Saranath, D1
Deo, MG1
Berger, MR1
Zerban, H1
Lu, SH1
Yang, WX1
Guo, LP1
Li, FM1
Wang, GJ1
Zhang, JS1
Li, PZ1
Shirai, T1
Tsuda, H1
Ogiso, T1
Hirose, M1
Ito, N1
Bertram, B1
Frei, E1
Scherf, HR1
Schuhmacher, J1
Tacchi, AM1
Wiessler, M1
Sons, HU1
Borchard, F1
Müller-Jäh, K1
Sandmann, H1

Other Studies

55 other studies available for diethylnitrosamine and Cancer of Esophagus

ArticleYear
Hamster exhibits major differences in organ-specific metabolism of the esophageal carcinogen N-nitrosodiethylamine.
    Toxicology letters, 2008, Dec-15, Volume: 183, Issue:1-3

    Topics: Alkylating Agents; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Carcinogens; Cricetina

2008
Maté attenuates DNA damage and carcinogenesis induced by diethylnitrosamine and thermal injury in rat esophagus.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Aquifoliaceae; Aspartate Aminotransferases; Beverages; Body Weight

2009
Evaluation of the heme oxygenase-1 expression in esophagitis and esophageal cancer induced by different reflux experimental models and diethylnitrosamine.
    Acta cirurgica brasileira, 2010, Volume: 25, Issue:3

    Topics: Animals; Biomarkers; Carcinogens; Carcinoma; Diethylnitrosamine; Disease Models, Animal; Esophageal

2010
[Immunohistochemical expression of P53 and Ki-67 in diethylnitrosamine-induced carcinomas esophageal: experimental model].
    Revista do Colegio Brasileiro de Cirurgioes, 2010, Volume: 37, Issue:2

    Topics: Animals; Carcinoma, Squamous Cell; Diethylnitrosamine; Esophageal Neoplasms; Female; Immunohistochem

2010
Cytotoxicity of fumonisin B1, diethylnitrosamine, and catechol on the SNO esophageal cancer cell line.
    Environmental health perspectives, 2002, Volume: 110, Issue:8

    Topics: Alkylating Agents; Carboxylic Acids; Carcinogens, Environmental; Catechols; Cell Transformation, Neo

2002
Dietary exposure and urinary excretion of total N-nitroso compounds, nitrosamino acids and volatile nitrosamine in inhabitants of high- and low-risk areas for esophageal cancer in southern China.
    International journal of cancer, 2002, Nov-20, Volume: 102, Issue:3

    Topics: Adult; Carboxylic Acids; China; Diet; Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasms;

2002
Experimental esophageal carcinogenesis: technical standardization and results.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2002, Volume: 15, Issue:4

    Topics: Alkylating Agents; Animals; Carcinogenicity Tests; Diethylnitrosamine; Disease Models, Animal; Esoph

2002
Threshold for carcinogenicity of N-nitrosodiethylamine for esophageal tumors in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2003, Volume: 41, Issue:5

    Topics: Alkylating Agents; Animals; Carcinogens; Diethylnitrosamine; Dose-Response Relationship, Drug; Esoph

2003
[QUANTITATIVE ANALYSIS OF THE CARCINOGENIC EFFECT OF DIETHYLNITROSAMINE].
    Arzneimittel-Forschung, 1963, Volume: 13

    Topics: Carcinogens; Carcinoma, Hepatocellular; Diethylnitrosamine; DNA; DNA, Neoplasm; Esophageal Neoplasms

1963
Diethylnitrosamine may induce esophageal dysplasia after local intramural administration.
    Roczniki Akademii Medycznej w Bialymstoku (1995), 2003, Volume: 48

    Topics: Alkylating Agents; Animals; Diethylnitrosamine; Esophageal Neoplasms; Injections; Male; Models, Anim

2003
Effects of acetylsalicylic acid and celecoxib on the N-nitrosodiethylamine induced carcinogenesis in rat liver and esophagus.
    Bulletin of experimental biology and medicine, 2007, Volume: 143, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Celecoxib; Dieth

2007
[Cancer of the esophagus induced in the Wistar rat by ethyl-N-butyl-nitrosamine].
    Bulletin du cancer, 1984, Volume: 71, Issue:5

    Topics: Animals; Carcinoma; Cheek; Diethylnitrosamine; Esophageal Neoplasms; Female; Liver Neoplasms; Male;

1984
The possible role of nitrosamines in the link between alcohol consumption and esophageal cancer in man.
    Toxicologic pathology, 1984, Volume: 12, Issue:4

    Topics: Alcohol Drinking; Diethylnitrosamine; Digestive System; Esophageal Neoplasms; Humans; Nitrosamines;

1984
Antitumoral activity of indomethacin on experimental esophageal tumors.
    Journal of the National Cancer Institute, 1984, Volume: 72, Issue:3

    Topics: Animals; Diethylnitrosamine; Drug Administration Schedule; Esophageal Neoplasms; Indomethacin; Male;

1984
[Studies on canceration of esophageal epithelium--(SEM) and (TEM) observations].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1983, Volume: 5, Issue:1

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; Dimethylnitrosamine; Epit

1983
Epithelial lesions antedating oesophageal carcinoma. I. Histologic study in mice.
    Pathology, research and practice, 1983, Volume: 176, Issue:2-4

    Topics: Animals; Carcinoma in Situ; Carcinoma, Squamous Cell; Diethylnitrosamine; Epithelium; Esophageal Neo

1983
Species specificity in nitrosamine carcinogenesis.
    Basic life sciences, 1983, Volume: 24

    Topics: Animals; Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasms; Liver Neoplasms; Lung Neopla

1983
Inhibition of the hepatocarcinogenic activity of diethylnitrosamine (DENA) by ethanol in rats.
    Hepato-gastroenterology, 1981, Volume: 28, Issue:5

    Topics: Animals; Diethylnitrosamine; Esophageal Neoplasms; Ethanol; Liver Neoplasms, Experimental; Male; Neo

1981
Tumours induced in Fischer 344 rats by the feeding of disulfiram together with sodium nitrite.
    Food and cosmetics toxicology, 1980, Volume: 18, Issue:1

    Topics: Animals; Carcinogens; Diet; Diethylnitrosamine; Disulfiram; Drug Interactions; Esophageal Neoplasms;

1980
Interferon-alpha/beta can impede development of carcinogen-induced squamous-cell tumors in the esophagus of C57B1 mice.
    International journal of cancer, 1995, Jul-04, Volume: 62, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Diethylnitrosamine; Esophageal Neoplasms; Interferon-alpha; Inter

1995
[N-nitroso-compounds of pickles in the areas with high incidence of digestive cancers and their mutagenic effects].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1994, Volume: 28, Issue:4

    Topics: Animals; Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasms; Food Preservation; Liver Neo

1994
Modulation of diethylnitrosamine carcinogenesis in rat liver and oesophagus.
    Journal of cellular biochemistry, 1994, Volume: 56, Issue:4

    Topics: Animals; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Caffeine; Diethylnitrosamine; Disease M

1994
Enhancing effect of ethanol on esophageal tumor development in rats by initiation of diethylnitrosamine.
    Carcinogenesis, 1993, Volume: 14, Issue:1

    Topics: Animals; Cocarcinogenesis; Diethylnitrosamine; Esophageal Neoplasms; Esophagus; Ethanol; Hyperplasia

1993
Enhanced expression of a new class of liver-enriched b-Zip transcription factors, hepatocarcinogenesis-related transcription factor, in hepatocellular carcinomas of rats and humans.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1998, Volume: 9, Issue:4

    Topics: Animals; Basic-Leucine Zipper Transcription Factors; Carcinogens; Carcinoma, Hepatocellular; Cell Di

1998
Induction of esophageal carcinogenesis by diethylnitrosamine and assessment of the promoting effect of ethanol and N-nitrosonornicotine: experimental model in mice.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 1999, Volume: 12, Issue:2

    Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Diethylnitrosamine; Esophageal Neoplasms; Esophagus;

1999
Influence of surgically induced gastric and gastroduodenal content reflux on esophageal carcinogenesis--experimental model in Wistar female rats.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 1999, Volume: 12, Issue:2

    Topics: Adenocarcinoma; Animals; Barrett Esophagus; Carcinogens; Carcinoma, Squamous Cell; Diethylnitrosamin

1999
Effects of N-acetylcysteine in an esophageal carcinogenesis model in rats treated with diethylnitrosamine and diethyldithiocarbamate.
    International journal of cancer, 2002, Apr-01, Volume: 98, Issue:4

    Topics: Acetylcysteine; Animals; Diethylnitrosamine; Ditiocarb; Drug Synergism; Esophageal Neoplasms; Esopha

2002
Effect of ethanol treatment on metabolic activation and detoxification of esophagus carcinogenic N-nitrosamines in rat liver.
    Mutagenesis, 2002, Volume: 17, Issue:3

    Topics: Animals; Blotting, Western; Carcinogens; Cytochrome P-450 CYP2E1; Densitometry; Diethylnitrosamine;

2002
[Modification of chemical carcinogenesis with adrenergic compounds].
    Vestnik Akademii meditsinskikh nauk SSSR, 1978, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Drug Ant

1978
Reduction of N-nitrosodiethylamine carcinogenesis in rats by lipotrope or amino acid supplementation of a marginally deficient diet.
    Cancer research, 1977, Volume: 37, Issue:1

    Topics: Amino Acids; Animals; Body Weight; Carcinoma, Hepatocellular; Choline; Diet; Dietary Fats; Diethylni

1977
Influence of disulfiram on the organotropy of the carcinogenic effect of dimethylnitrosamine and diethylnitrosamine in rats.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1976, Mar-19, Volume: 85, Issue:3

    Topics: Animals; Diethylnitrosamine; Dimethylnitrosamine; Disulfiram; Esophageal Neoplasms; Liver Neoplasms;

1976
Carcinogenicity of methylated derivatives of N-nitrosodiethylamine and related compounds in Sprague-Dawley rats.
    Journal of the National Cancer Institute, 1979, Volume: 62, Issue:2

    Topics: Animals; Carcinogens; Diethylnitrosamine; Esophageal Neoplasms; Female; Liver Neoplasms; Male; Methy

1979
Intake of volatile nitrosamines from consumption of alcohols.
    Journal of the National Cancer Institute, 1979, Volume: 63, Issue:4

    Topics: Alcoholic Beverages; Alcoholism; Beer; Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasms

1979
[Comparative investigations on the organotropic carcinogenic effect of different N-nitroso compounds with rat after single and chronic treatment (author's transl)].
    Journal of cancer research and clinical oncology, 1979, Volume: 95, Issue:2

    Topics: Animals; Benzyl Compounds; Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasms; Female; Ki

1979
Relative carcinogenic effectiveness of derivatives of nitrosodiethylamine in rats.
    Cancer research, 1978, Volume: 38, Issue:8

    Topics: Administration, Oral; Animals; Diethylnitrosamine; Esophageal Neoplasms; Liver Neoplasms; Neoplasms,

1978
Histopathology of preneoplastic and neoplastic lesions of the esophagus in BUF rats ingesting diethylnitrosamine.
    Journal of the National Cancer Institute, 1977, Volume: 58, Issue:2

    Topics: Animals; Carcinoma; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Diethylnitrosamine; Esophageal

1977
Combination effects in chemical carcinogenesis (experimental results).
    Oncology, 1976, Volume: 33, Issue:2

    Topics: Animals; Carcinogens; Cocarcinogenesis; Cyclamates; Diethylnitrosamine; Disease Models, Animal; Dose

1976
Effect of age and sex on lesions of the esophagus in Buffalo strain rats ingesting diethylnitrosamine.
    Experimental cell biology, 1976, Volume: 44, Issue:2

    Topics: Age Factors; Animals; Diethylnitrosamine; Esophageal Neoplasms; Female; Liver Neoplasms; Male; Neopl

1976
Carcinomas of the esophagus in rats ingesting diethylnitrosamine.
    European journal of cancer, 1975, Volume: 11, Issue:2

    Topics: Administration, Oral; Animals; Bronchopneumonia; Carcinoma; Carcinoma, Squamous Cell; Diethylnitrosa

1975
Effect of diet on DEN clearance and carcinogenesis in rats.
    British journal of cancer, 1975, Volume: 31, Issue:6

    Topics: Animals; Diet; Diethylnitrosamine; Esophageal Neoplasms; Liver Neoplasms; Male; Neoplasms, Experimen

1975
Carcinogenic effects of different nitroso-compounds in Chinese hamsters. I. Dimethylnitrosamine and N-diethylnitrosamine.
    British journal of cancer, 1976, Volume: 33, Issue:4

    Topics: Animals; Cricetinae; Diethylnitrosamine; Dimethylnitrosamine; Dose-Response Relationship, Drug; Esop

1976
[Studies of pickled vegetables and cause of esophageal cancer in Linxian. II. Determination of nitrosamines and their precursors].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1991, Volume: 13, Issue:3

    Topics: Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasms; Food Preservation; Humans; Nitrates;

1991
Effects on 4080 rats of chronic ingestion of N-nitrosodiethylamine or N-nitrosodimethylamine: a detailed dose-response study.
    Cancer research, 1991, Dec-01, Volume: 51, Issue:23 Pt 2

    Topics: Animals; Bile Duct Neoplasms; Carcinogenicity Tests; Diethylnitrosamine; Dimethylnitrosamine; Dose-R

1991
Dose and time relationships for tumor induction in the liver and esophagus of 4080 inbred rats by chronic ingestion of N-nitrosodiethylamine or N-nitrosodimethylamine.
    Cancer research, 1991, Dec-01, Volume: 51, Issue:23 Pt 2

    Topics: Age Factors; Animals; Carcinogenicity Tests; Diethylnitrosamine; Dimethylnitrosamine; Dose-Response

1991
Chronic nitrosamine ingestion in 1040 rodents: the effect of the choice of nitrosamine, the species studied, and the age of starting exposure.
    Cancer research, 1991, Dec-01, Volume: 51, Issue:23 Pt 2

    Topics: Age Factors; Animals; Carcinogens; Cricetinae; Diethylnitrosamine; Dimethylnitrosamine; Esophageal N

1991
Rat hepatocarcinogenesis induced by N-nitrosodiethylamine and N-nitrosomorpholine continuously administered at low doses. From basophilic areas of hepatocytes to hepatocellular tumors.
    The American journal of pathology, 1991, Volume: 139, Issue:5

    Topics: Adenoma; Administration, Oral; Animals; Carcinogens; Diethylnitrosamine; Dose-Response Relationship,

1991
Free radicals generated in ethanol metabolism may be responsible for tumor promoting effects of ethanol.
    Advances in experimental medicine and biology, 1991, Volume: 283

    Topics: Animals; Carcinogens; Cocarcinogenesis; Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasm

1991
ICRC mouse with congenital mega-esophagus as a model to study esophageal tumorigenesis.
    Carcinogenesis, 1989, Volume: 10, Issue:10

    Topics: Aging; Animals; Diethylnitrosamine; Esophageal Neoplasms; Esophagus; Female; Male; Mice; Mice, Inbre

1989
Post-carcinogen interval in carcinogenesis.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:3

    Topics: Animals; Diethylnitrosamine; Esophageal Neoplasms; Mice; Mice, Inbred C57BL; Time Factors

1988
Combination experiments with very low doses of three genotoxic N-nitrosamines with similar organotropic carcinogenicity in rats.
    Carcinogenesis, 1987, Volume: 8, Issue:11

    Topics: Animals; Carcinogens; Cocarcinogenesis; Diethylnitrosamine; Dose-Response Relationship, Drug; Drug C

1987
Determination of N-nitrosamines in gastric juice and urine and a comparison of endogenous formation of N-nitrosoproline and its inhibition in subjects from high- and low-risk areas for oesophageal cancer.
    IARC scientific publications, 1987, Issue:84

    Topics: China; Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasms; Gastric Juice; Humans; Nitrosa

1987
Further studies on the therapeutic effect of indomethacin on esophageal tumors.
    Cancer, 1986, Sep-01, Volume: 58, Issue:5

    Topics: Animals; Diethylnitrosamine; Esophageal Neoplasms; Female; Indomethacin; Mice; Mice, Inbred C57BL

1986
Organ specific modifying potential of ethinyl estradiol on carcinogenesis initiated with different carcinogens.
    Carcinogenesis, 1987, Volume: 8, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Drug Interactio

1987
Influence of a prolonged treatment with disulfiram and D(-)penicillamine on nitrosodiethylamine-induced biological and biochemical effects in rats. I. Investigations on the drug metabolizing system.
    Journal of cancer research and clinical oncology, 1985, Volume: 109, Issue:1

    Topics: Animals; Diethylnitrosamine; Disulfiram; Drug Interactions; Enzyme Inhibitors; Esophageal Neoplasms;

1985
Accelerated tumor induction by distal esophageal constriction in the rat under the influence of N-ethyl-N-butyl-nitrosamine.
    Cancer, 1985, Dec-01, Volume: 56, Issue:11

    Topics: Animals; Carcinogens; Cocarcinogenesis; Diethylnitrosamine; Esophageal Neoplasms; Esophageal Stenosi

1985