n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Cancer of Esophagus in 17 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two esophageal adenocarcinoma cell lines (SEG-1 and BIC) and two esophageal squamous cell cancer lines (KYSE 150 and KYSE 410) were treated with rofecoxib at doses ranging from 8." | 3.72 | Antiproliferative and apoptotic effects of rofecoxib on esophageal cancer in vitro(1). ( Jackson, BJ; McFadden, DW; Riggs, DR; Vona-Davis, L, 2004) |
| "The treatment of Barrett's esophagus is controversial." | 2.43 | [The clinical strategy for the Barrett's esophagus]. ( Goto, H; Kitabatake, S; Niwa, Y, 2005) |
| "The esophageal squamous cell carcinoma cell line TE-13 was cultured with NS-398 at different concentrations or for different times." | 1.35 | NS-398 induces apoptosis in human esophageal cancer cells through inhibition of NF-kappaB downstream regulation of cyclooxygenase-2. ( Drew, PA; Jamieson, GG; Liu, JF; Shan, BE; Wu, TC; Zhu, GJ; Zhu, TN, 2009) |
| "The incidence of oesophageal cancer (OC) has risen in recent decades, with survival rates remaining poor despite surgical treatment and adjuvant chemotherapy." | 1.34 | Cyclooxygenase-2 inhibitors demonstrate anti-proliferative effects in oesophageal cancer cells by prostaglandin E(2)-independent mechanisms. ( Deasy, BM; McKenna, SL; O'Donovan, TR; O'Sullivan, GC; O'Sullivan-Coyne, G, 2007) |
| "Adenocarcinoma in Barrett's esophagus has been increasing in incidence at a rapid rate for more than two decades." | 1.31 | Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells. ( Beer, DG; Cryer, B; Shewmake, K; Souza, RF; Spechler, SJ, 2000) |
| "NSAIDs similarly induce apoptosis in esophageal cancer cells, although the mechanisms of these effects remain to be defined." | 1.31 | Nonsteroidal anti-inflammatory drugs induce apoptosis in esophageal cancer cells by restoring 15-lipoxygenase-1 expression. ( Chen, D; Fischer, SM; Lippman, SM; Lotan, R; Morris, JS; Shureiqi, I; Xu, X, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 13 (76.47) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, MF | 1 |
| Chen, PT | 1 |
| Lu, MS | 1 |
| Chen, WC | 1 |
| Liu, JF | 1 |
| Zhu, GJ | 1 |
| Jamieson, GG | 1 |
| Wu, TC | 1 |
| Zhu, TN | 1 |
| Shan, BE | 1 |
| Drew, PA | 1 |
| Che, SM | 2 |
| Zhang, XZ | 2 |
| Hou, L | 2 |
| Song, TB | 1 |
| Liu, XL | 1 |
| Chen, X | 1 |
| Li, S | 2 |
| Tian, D | 1 |
| Fei, P | 1 |
| Gao, Y | 1 |
| Chen, Z | 2 |
| Wang, Q | 2 |
| Tong, Q | 2 |
| Vona-Davis, L | 1 |
| Riggs, DR | 1 |
| Jackson, BJ | 1 |
| McFadden, DW | 1 |
| Yu, HP | 1 |
| Shi, LY | 1 |
| Lu, WH | 1 |
| Su, YH | 1 |
| Li, YY | 1 |
| Xu, SQ | 1 |
| Kase, S | 1 |
| Osaki, M | 1 |
| Honjo, S | 1 |
| Takeda, A | 1 |
| Adachi, K | 1 |
| Araki, K | 1 |
| Ito, H | 1 |
| Kitabatake, S | 1 |
| Niwa, Y | 1 |
| Goto, H | 1 |
| Zhi, H | 1 |
| Wang, L | 1 |
| Zhang, J | 1 |
| Zhou, C | 1 |
| Ding, F | 1 |
| Luo, A | 1 |
| Wu, M | 1 |
| Zhan, Q | 1 |
| Liu, Z | 1 |
| Baguma-Nibasheka, M | 1 |
| Barclay, C | 1 |
| Li, AW | 1 |
| Geldenhuys, L | 1 |
| Porter, GA | 1 |
| Blay, J | 1 |
| Casson, AG | 1 |
| Murphy, PR | 1 |
| Deasy, BM | 1 |
| O'Sullivan-Coyne, G | 1 |
| O'Donovan, TR | 1 |
| McKenna, SL | 1 |
| O'Sullivan, GC | 1 |
| Ogunwobi, OO | 1 |
| Beales, IL | 1 |
| Zhang, W | 1 |
| Wu, Q | 1 |
| Souza, RF | 1 |
| Shewmake, K | 1 |
| Beer, DG | 1 |
| Cryer, B | 1 |
| Spechler, SJ | 1 |
| Shureiqi, I | 1 |
| Xu, X | 1 |
| Chen, D | 1 |
| Lotan, R | 1 |
| Morris, JS | 1 |
| Fischer, SM | 1 |
| Lippman, SM | 1 |
| Li, M | 1 |
| Wu, X | 1 |
| Xu, XC | 1 |
1 review available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Cancer of Esophagus
| Article | Year |
|---|---|
[The clinical strategy for the Barrett's esophagus].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Ba | 2005 |
16 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Cancer of Esophagus
| Article | Year |
|---|---|
Role of ALDH1 in the prognosis of esophageal cancer and its relationship with tumor microenvironment.
Topics: Adult; Aged; Aged, 80 and over; Aldehyde Dehydrogenase 1 Family; Animals; Carcinoma, Squamous Cell; | 2018 |
NS-398 induces apoptosis in human esophageal cancer cells through inhibition of NF-kappaB downstream regulation of cyclooxygenase-2.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cel | 2009 |
Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis.
Topics: Apoptosis; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Down-Regulation; Esophageal Neoplasms; Hum | 2010 |
The radiosensitization effect of NS398 on esophageal cancer stem cell-like radioresistant cells.
Topics: Apoptosis; beta Catenin; Blotting, Western; Carcinogenicity Tests; Cell Survival; Cyclooxygenase Inh | 2011 |
A cyclooxygase-2 inhibitor NS-398-enhanced apoptosis of esophageal carcinoma cell EC9706 by adjusting expression of survivin and caspase-3.
Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Esophageal | 2011 |
Antiproliferative and apoptotic effects of rofecoxib on esophageal cancer in vitro(1).
Topics: Adenocarcinoma; Apoptosis; Cell Division; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Cycl | 2004 |
Expression of cyclooxygenase-2 (COX-2) in human esophageal cancer and in vitro inhibition by a specific COX-2 inhibitor, NS-398.
Topics: Apoptosis; Carcinoma, Squamous Cell; Caspase 3; Caspases; Cell Division; Cyclooxygenase 2; Cyclooxyg | 2004 |
A selective cyclooxygenase-2 inhibitor, NS398, inhibits cell growth and induces cell cycle arrest in the G2/M phase in human esophageal squamous cell carcinoma cells.
Topics: Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Carrier Proteins; Cell Division; Cyclin B; C | 2004 |
Significance of COX-2 expression in human esophageal squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Disease Progres | 2006 |
Selective cyclooxygenase-2 inhibition suppresses basic fibroblast growth factor expression in human esophageal adenocarcinoma.
Topics: Adenocarcinoma; Aged; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Cyclooxygenase 2 | 2007 |
Cyclooxygenase-2 inhibitors demonstrate anti-proliferative effects in oesophageal cancer cells by prostaglandin E(2)-independent mechanisms.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; C | 2007 |
Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells.
Topics: Adenocarcinoma; Analysis of Variance; Animals; Apoptosis; Barrett Esophagus; Caspase 3; Cell Divisio | 2008 |
Mechanism of growth inhibitory effects of cyclooxygenase-2 inhibitor-NS398 on cancer cells.
Topics: Apoptosis; Carcinoma; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; Cyclooxygenase 2; | 2008 |
Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Barrett Esophagus; Cell Division | 2000 |
Nonsteroidal anti-inflammatory drugs induce apoptosis in esophageal cancer cells by restoring 15-lipoxygenase-1 expression.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Arachidonate 15-Lipoxygenase; Ca | 2001 |
Induction of apoptosis by cyclo-oxygenase-2 inhibitor NS398 through a cytochrome C-dependent pathway in esophageal cancer cells.
Topics: Apoptosis; Caspase Inhibitors; Caspases; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitor | 2001 |