Compounds > sargachromanol g
Page last updated: 2024-11-12

sargachromanol g

Description

sargachromanol G: isolated from the brown algae Sargassum siliquastrum; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID11407674
CHEMBL ID462917
MeSH IDM0580225

Synonyms (5)

Synonym
sargachromanol g
CHEMBL462917
bdbm50483666
DTXSID801045700
856414-56-7
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (14)

Assay IDTitleYearJournalArticle
AID590287Antifungal activity against Aspergillus fumigatus HIC 6094 at 100 ug/ml after 2 weeks2011Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7
Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase.
AID590286Antifungal activity against Candida albicans ATCC 10231 at 100 ug/ml after 2 weeks2011Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7
Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase.
AID590291Antifungal activity against Trichophyton mentagrophytes IFO 40996 at 100 ug/ml after 2 weeks2011Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7
Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase.
AID590285Antibacterial activity against Proteus vulgaris ATCC 3851 after 24 hrs by by broth dilution method2011Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7
Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase.
AID590280Inhibition of porcine cerebral cortex Na+/K+ ATPase by spectrophotometry2011Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7
Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase.
AID590290Antifungal activity against Trichophyton rubrum IFO 9185 at 100 ug/ml after 2 weeks2011Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7
Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase.
AID590284Antibacterial activity against Micrococcus luteus IFC 12708 after 24 hrs by by broth dilution method2011Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7
Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase.
AID590283Antibacterial activity against Staphylococcus aureus ATCC 6538p after 24 hrs by broth dilution method2011Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7
Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase.
AID401695Inhibition of butylcholine esterase at 100 ug/mL2005Journal of natural products, May, Volume: 68, Issue:5
Chromenes from the brown alga Sargassum siliquastrum.
AID590282Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by broth dilution method2011Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7
Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase.
AID590281Inhibition of Candida albicans ICL assessed as formation of glyoxylate phenylhydrazone by spectrophotometry2011Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7
Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase.
AID590289Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by broth dilution method2011Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7
Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase.
AID590288Antibacterial activity against Salmonella Typhimurium ATCC 14028 after 24 hrs by broth dilution method2011Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7
Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase.
AID401694Antioxidant activity assessed as DPPH radical scavenging activity at 100 ug/mL2005Journal of natural products, May, Volume: 68, Issue:5
Chromenes from the brown alga Sargassum siliquastrum.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 13.28

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index13.28 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index5.08 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (13.28)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
3-nitropropionic acid
3-nitropropionic acid: succinate dehydrogenase inactivator; biosynthesized by FABACEAE plants from ASPARAGINE. 3-nitropropanoic acid : A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.		2.0610C-nitro compoundantimycobacterial drug;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor;
mycotoxin;
neurotoxin
ampicillin
Ampicillin: Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.. ampicillin : A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group.		2.0610beta-lactam antibiotic;
penicillin allergen;
penicillin		antibacterial drug
ouabain
Ouabain: A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE.. cardiac glycoside : Steroid lactones containing sugar residues that act on the contractile force of the cardiac muscles.. ouabain : A steroid hormone that is a multi-hydroxylated alpha-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na(+)/K(+)-ATPase (sodium pump). It has been isolated naturally from Strophanthus gratus.		2.061011alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone		anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite
osteoprotegerin
Osteoprotegerin: A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.		2.0710long-chain fatty acid
dinoprostone
prostaglandin E2 : Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins.		2.0710prostaglandins Ehuman metabolite;
mouse metabolite;
oxytocic
acid phosphatase
Acid Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.		2.0810
ConditionIndicatedRelationship StrengthStudiesTrials
Innate Inflammatory Response
[description not available]		02.0710
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.		02.0710
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