Compounds > octachlorocyclotetraphosphazene
Page last updated: 2024-11-06

octachlorocyclotetraphosphazene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

Octachlorocyclotetraphosphazene (N4P4Cl8) is a cyclic inorganic compound that serves as a versatile precursor for synthesizing a wide range of phosphorus-nitrogen compounds. Its synthesis involves the reaction of phosphorus pentachloride (PCl5) with ammonium chloride (NH4Cl). The compound is a white crystalline solid, highly reactive, and sensitive to moisture. Its unique structure with alternating phosphorus and nitrogen atoms in a ring allows for various substitutions, leading to the formation of polymers, ceramics, and flame retardants. Due to its potential applications in these areas, octachlorocyclotetraphosphazene has been extensively studied for its synthesis, reactivity, and properties.'

octachlorocyclotetraphosphazene: RN from CA, 90, Form Index; RN given refers to parent cpd; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID76285
CHEMBL ID3344300
MeSH IDM0078894

Synonyms (31)

Synonym
einecs 220-972-1
2,2,4,4,6,6,8,8-octachloro-2,2,4,4,6,6,8,8-octahydro-1,3,5,7,2,4,6,8-tetraazatetraphosphocine
2lambda5,4lambda5,6lambda5,8lambda5-1,3,5,7,2,4,6,8-tetrazatetraphosphocine, 2,2,4,4,6,6,8,8-octachloro-
nsc 37389
1,1,3,3,5,5,7,7-octachlorocyclotetraphosphaza-1,3,5,7-tetraene
1,3,5,7,2,4,6,8-tetrazatetraphosphocine, 2,2,4,4,6,6,8,8-octachloro-2,2,4,4,6,6,8,8-octahydro-
octachlorocyclotetraphosphazene
nsc37389
octachlorocyclotetraphosphazatetraene
nsc-37389
1,5,7,2,4,6,8-tetrazatetraphosphocine, 2,2,4,4,6,6,8,8-octachloro-2,2,4,4,6,6,8,8-octahydro-
phosphonitrilic chloride cyclic tetramer
phosphonitrile chloride, cyclic tetramer
phosphonitrile chloride, tetramer
1,3,3,5,5,7,7-octachlorocyclotetraphosphaza-1,3,5,7-tetraene
nitrogen chloride phosphide ((npcl2)4)
tetraphosphonitrile chloride
2950-45-0
octachlorotetraphosphonitrile
octachlorocyclophosphazatetraene
AKOS000276225
phosphonitrilic chloride
DTXSID7062740
tetraphosphonitrilic chloride
2.lambda.5,4.lambda.5,6.lambda.5,8.lambda.5-1,3,5,7,2,4,6,8-tetrazatetraphosphocine, 2,2,4,4,6,6,8,8-octachloro-
cyclo-tetrakis(dichlorophosphonitrile)
CHEMBL3344300
2,2,4,4,6,6,8,8-octachloro-1,3,5,7,2lambda~5~,4lambda~5~,6lambda~5~,8lambda~5~-tetraazatetraphosphocine
n4p4cl8
cyclo-tetrakis(phosphorus(v) nitride dichloride)
2,2,4,4,6,6,8,8-octachloro-1,3,5,7-tetraza-2lambda5,4lambda5,6lambda5,8lambda5-tetraphosphacycloocta-1,3,5,7-tetraene

Research Excerpts

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID1168642Antimicrobial activity against Bacillus cereus NRRL-B-3711 after 18 hrs by agar well diffusion assay2014European journal of medicinal chemistry, Nov-24, Volume: 87Phosphorus-nitrogen compounds. Part 29. Syntheses, crystal structures, spectroscopic and stereogenic properties, electrochemical investigations, antituberculosis, antimicrobial and cytotoxic activities and DNA interactions of ansa-spiro-ansa cyclotetrapho
AID1168645Binding affinity to Escherichia coli pBR322 plasmid DNA assessed as reduction in mobility of form-1 DNA at 312 to 5000 uM after 24 hrs by agarose gel electrophoresis2014European journal of medicinal chemistry, Nov-24, Volume: 87Phosphorus-nitrogen compounds. Part 29. Syntheses, crystal structures, spectroscopic and stereogenic properties, electrochemical investigations, antituberculosis, antimicrobial and cytotoxic activities and DNA interactions of ansa-spiro-ansa cyclotetrapho
AID1168625Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 after 18 hrs by agar well diffusion assay2014European journal of medicinal chemistry, Nov-24, Volume: 87Phosphorus-nitrogen compounds. Part 29. Syntheses, crystal structures, spectroscopic and stereogenic properties, electrochemical investigations, antituberculosis, antimicrobial and cytotoxic activities and DNA interactions of ansa-spiro-ansa cyclotetrapho
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
chlorine
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.		2.1110halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
ketoconazole
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.		2.110dichlorobenzene;
dioxolane;
ether;
imidazoles;
N-acylpiperazine;
N-arylpiperazine
chloramphenicol
Amphenicol: Chloramphenicol and its derivatives.		2.110C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor
ampicillin
Ampicillin: Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.. ampicillin : A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group.		2.110beta-lactam antibiotic;
penicillin allergen;
penicillin		antibacterial drug
4-bromophenol
4-bromophenol : A bromophenol containing only hydroxy and bromo substituents that are para to one another.		1.9810bromophenolhuman urinary metabolite;
human xenobiotic metabolite;
marine metabolite;
mouse metabolite;
persistent organic pollutant;
rat metabolite
tetrahydrofuran
oxolane : A cyclic ether that is butane in which one hydrogen from each methyl group is substituted by an oxygen.		2.1110cyclic ether;
oxolanes;
saturated organic heteromonocyclic parent;
volatile organic compound		polar aprotic solvent
piperidine
[no description available]		2.110azacycloalkane;
piperidines;
saturated organic heteromonocyclic parent;
secondary amine		base;
catalyst;
human metabolite;
non-polar solvent;
plant metabolite;
protic solvent;
reagent
hydroxyethyl methacrylate
hydroxyethyl methacrylate: many of cited refs are for gel which refers to polymeric form of above cpd: POLYHYDROXYETHYL METHACRYLATE. 2-hydroxyethyl methacrylate : An enoate ester that is the monomethacryloyl derivative of ethylene glycol.		2.3820enoate esterallergen;
polymerisation monomer
bisphenol a-glycidyl methacrylate
Bisphenol A-Glycidyl Methacrylate: The reaction product of bisphenol A and glycidyl methacrylate that undergoes polymerization when exposed to ultraviolet light or mixed with a catalyst. It is used as a bond implant material and as the resin component of dental sealants and composite restorative materials.		1.9810diarylmethane
sodium hydride
[no description available]		2.1110
hexachlorocyclotriphosphazene
hexachlorocyclotriphosphazene: RN given refers to parent cpd; structure		1.9810
phosphorus
Phosphorus: A non-metal element that has the atomic symbol P, atomic number 15, and atomic weight 31. It is an essential element that takes part in a broad variety of biochemical reactions.		1.9810monoatomic phosphorus;
nonmetal atom;
pnictogen		macronutrient
ConditionIndicatedRelationship StrengthStudiesTrials