Histiocytosis, Non-Langerhans-Cell

Group of disorders which feature accumulations of active HISTIOCYTES and LYMPHOCYTES, but where the histiocytes are not LANGERHANS CELLS. The group includes HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; SINUS HISTIOCYTOSIS; xanthogranuloma; reticulohistiocytoma; JUVENILE XANTHOGRANULOMA; xanthoma disseminatum; as well as the lipid storage diseases (SEA-BLUE HISTIOCYTE SYNDROME; and NIEMANN-PICK DISEASES).

Synonym
Histiocytosis, Non-Langerhans-Cell
Reticulohistiocytoma
Xanthoma Disseminatum

Excerpt	Reference
"Reticulohistiocytoma is a rare, benign histiocytic lesion usually occurring as an isolated skin nodule or as part of a systemic disorder known as "multicentric reticulohistiocytosis."	( Allaire, GS; Hidayat, AA; Minardi, L; Zimmerman, LE, 1990)
"Xanthoma disseminatum is a rare non-Langerhans' histiocytosis of older children and adults with characteristic lesions involving the skin, mucous membrane and occasionally internal organs."	( Barr, RD; Calverly, DC; deSa, D; Rosenthal, D; Wismer, J, 1995)
"Xanthoma disseminatum is a rare nonfamilial disease characterized by lipid deposition in skin and internal organs due to histiocytic cell proliferation, classified as a benign non-Langerhans cell histiocytosis."	( Gibson, LE; Khezri, F; Tefferi, A, 2011)
"Xanthoma disseminatum is a non-Langerhans histiocytic proliferation first described by Montgomery in 1938."	( Benchikhi, H; Hali, F; Lazaar, S; Marnissi, F; Zinoun, M, 2015)

Excerpt	Reference
"The large reticulohistiocytoma resolved with methylprednisolone pulse therapy."	( Chen, CH; Chen, HA; Liao, HT; Lin, HY, 2006)
"We report 8 cases of xanthoma disseminatum with treatment outcomes in long-term follow-up and provide a review of the medical literature."	( Gibson, LE; Khezri, F; Tefferi, A, 2011)
"Among 8 cases of xanthoma disseminatum, a positive response to treatment with 2-chlorodeoxyadenosine was seen in 5 cases."	( Gibson, LE; Khezri, F; Tefferi, A, 2011)
"With a diagnosis of xanthoma disseminatum with significant neurological involvement, he received cladribine therapy and showed significant improvement in both cutaneous and nervous system lesions."	( Bhari, N; Bhatia, S; Khaitan, BK; Patra, S, 2019)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	11 (2.91)	23.3326
1990's	130 (34.39)	12.5806
2000's	151 (39.95)	18.1394
2010's	61 (16.14)	28.8240
2020's	25 (6.61)	9.53

Drug	Relationship Strength	Studies	Trials
quinacrine	low	1	0
salicylic acid	low	2	0
phosphonoacetic acid	low	1	0
uric acid	low	1	0
homovanillic acid	low	1	0
phenytoin	low	1	0
hydroxyindoleacetic acid	low	1	0
acetazolamide	low	1	0
alendronate	low	3	0
aspirin	low	1	0
atenolol	low	1	0
azathioprine	low	3	0
verapamil	low	1	0
carbamazepine	low	1	0
chlorambucil	low	3	0
chloroquine	low	2	0
ciprofloxacin	low	1	0
clofibrate	low	1	0
fenofibrate	low	2	0
foscarnet	low	3	0
gabexate	low	1	0
gentamicin	low	1	0
hydrochlorothiazide	low	1	0
hydroxychloroquine	low	4	0
ifosfamide	low	2	0
isoniazid	low	3	0
lamotrigine	low	1	0
leflunomide	low	2	0
mebendazole	low	1	0
metronidazole	low	1	0
mitoxantrone	medium	1	1
pamidronate	low	1	0
phenobarbital	low	2	0
primaquine	low	1	0
prochlorperazine	low	1	0
sulfasalazine	low	2	0
thalidomide	low	1	0
2,4-thiazolidinedione	low	1	0
thiotepa	low	1	0
prednisolone	low	49	0
prednisone	low	29	0
penicillin g	low	1	0
alanine	low	1	0
serine	low	2	0
lysine	low	2	0
phenylalanine	low	1	0
ampicillin	low	1	0
cytarabine	medium	6	1
ornithine	low	1	0
valine	low	1	0
tryptophan	low	1	0
arginine	low	1	0
trichloroacetic acid	low	1	0
methylprednisolone	low	27	0
pyrroles	low	1	0
isoxazoles	low	2	0
pyrazines	low	1	0
nitroblue tetrazolium	low	2	0
fusarium	low	1	0
podophyllotoxin	low	2	0
erythromycin	low	1	0
vancomycin	low	1	0
betamethasone valerate	low	1	0
cladribine	low	8	0
carbenicillin	low	1	0
vidarabine	low	4	0
camptothecin	low	1	0
trolamine salicylate	low	66	0
danazol	low	1	0
daunorubicin	low	1	0
triamcinolone	low	1	0
gallium citrate	low	1	0
zidovudine	low	1	0
flubendazole	low	1	0
etoposide	medium	57	3
amikacin	low	3	0
vindesine	low	1	0
epirubicin	low	1	0
propiconazole	low	2	0
moxalactam	low	1	0
simvastatin	low	4	0
irinotecan	low	1	0
fluorodeoxyglucose f18	low	6	0
zoledronic acid	low	3	0
rosiglitazone	low	1	0
fibrinogen	low	1	0
imatinib mesylate	low	4	0
methotrexate	medium	46	1
proline	low	1	0
cortisone	low	1	0
carboplatin	low	1	0
inositol 3-phosphate	low	1	0
meropenem	low	1	0
tacrolimus	low	2	0
melphalan	low	3	0
fludarabine	low	3	0
mercaptopurine	low	2	0
D-fructopyranose	low	1	0
ferric ferrocyanide	low	1	0
quinine	low	3	0
alpha-chymotrypsin	low	1	0
osteoprotegerin	low	1	0
bilirubin	low	2	0
phenylephrine hydrochloride	low	3	0
acipimox	low	1	0
deamino arginine vasopressin	low	5	0
mitoguazone	low	1	0
antimony	low	1	0
barium	low	1	0
gallium	low	1	0
gadolinium dtpa	low	1	0
tofacitinib	low	1	0
pirarubicin	low	1	0
indocyanine green	low	1	0
pituitrin	low	1	0
acid phosphatase	low	1	0
mefloquine	low	2	0
ro13-9904	low	3	0
arginine	low	3	0
baricitinib	low	1	0
piperidines	low	1	0
interleukin-8	low	1	0
minocycline	low	1	0
warfarin	low	1	0
cyclin d1	low	1	0
cyclosporine	low	46	0
technetium tc 99m medronate	low	1	0
muramidase	low	2	0
exudates	low	2	0
acyclovir	low	6	0
neopterin	low	3	0
ganciclovir	low	6	0
eye	low	1	0
antimony sodium gluconate	low	1	0

Protein Targets (1,647)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Maltase-glucoamylase, intestinal	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Sucrase-isomaltase, intestinal	0	1	0	1
Glycogen synthase kinase-3 alpha	0	1	2	3
Glycogen synthase kinase-3 beta	0	2	2	4
Probable maltase-glucoamylase 2	0	1	0	1
5-hydroxytryptamine receptor 2C	0	3	1	5
5-hydroxytryptamine receptor 2A	0	3	1	4
5-hydroxytryptamine receptor 1A	0	8	2	10
5-hydroxytryptamine receptor 1B	0	5	1	6
5-hydroxytryptamine receptor 1D	0	1	1	2
5-hydroxytryptamine receptor 1F	0	1	1	2
5-hydroxytryptamine receptor 2B	0	2	1	3
5-hydroxytryptamine receptor 6	0	0	1	1
Sodium-dependent serotonin transporter	0	8	1	9
Sodium-dependent serotonin transporter	0	3	0	3
5-hydroxytryptamine receptor 7	0	0	1	1
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 4	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	18	0	0	18
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	13	0	0	13
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	2	0	2
thioredoxin reductase	29	0	0	29
GALC protein	8	0	0	8
GLI family zinc finger 3	38	0	0	38
nuclear receptor subfamily 1, group I, member 3	33	0	0	33
cytochrome P450 family 3 subfamily A polypeptide 4	23	0	0	23
glucocorticoid receptor [Homo sapiens]	34	0	0	34
retinoic acid nuclear receptor alpha variant 1	35	0	0	35
retinoid X nuclear receptor alpha	29	0	0	29
estrogen-related nuclear receptor alpha	37	0	0	37
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	1	0	1
arylsulfatase A	14	0	0	14
Carbonic anhydrase	0	1	0	1
euchromatic histone-lysine N-methyltransferase 2	38	0	0	38
Bloom syndrome protein isoform 1	19	0	0	19
thyroid hormone receptor beta isoform a	12	0	0	12
nuclear factor erythroid 2-related factor 2 isoform 1	35	0	0	35
geminin	43	0	0	43
peripheral myelin protein 22	19	0	0	19
survival motor neuron protein isoform d	18	0	0	18
muscleblind-like protein 1 isoform 1	10	0	0	10
Gamma-aminobutyric acid receptor subunit pi	16	3	1	20
ATP-binding cassette sub-family C member 3	0	44	0	44
Multidrug resistance-associated protein 4	0	44	0	45
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	7	0	9
Carbonic anhydrase 12	0	6	1	11
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Bile salt export pump	0	53	0	53
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Carbonic anhydrase 1	0	12	1	21
Carbonic anhydrase 2	0	15	2	23
Carbonic anhydrase 2	0	2	0	2
Cytochrome P450 1A2	0	8	0	8
Carbonic anhydrase 3	0	4	1	9
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	14	1	17
Steryl-sulfatase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cytochrome P450 2C8	0	4	0	5
Cytochrome P450 2D6	0	9	0	9
Cytochrome P450 2A6	0	3	0	3
Cytochrome P450 2C9	0	18	1	19
Androgen receptor	0	8	0	8
Gamma-aminobutyric acid receptor subunit beta-1	16	3	1	20
Translocator protein	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	16	3	1	20
Gamma-aminobutyric acid receptor subunit gamma-2	16	3	1	20
Gamma-aminobutyric acid receptor subunit alpha-5	16	3	1	20
Gamma-aminobutyric acid receptor subunit alpha-3	16	3	1	20
Cannabinoid receptor 1	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Cytochrome P450 2B6	0	2	1	3
Carbonic anhydrase 4	0	5	1	9
Carbonic anhydrase 6	0	4	1	8
Gamma-aminobutyric acid receptor subunit gamma-1	16	3	1	20
Gamma-aminobutyric acid receptor subunit alpha-2	16	3	1	20
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	3	0	4
Serum paraoxonase/arylesterase 1	0	3	0	3
Dipeptidyl peptidase 4	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	16	3	1	20
Gamma-aminobutyric acid receptor subunit gamma-3	16	3	1	20
Endochitinase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	16	3	1	20
Adenosine receptor A2a	0	3	0	4
Delta-type opioid receptor	0	3	0	3
Cytochrome P450 2C19	0	6	0	6
Delta-type opioid receptor	0	3	0	3
Mu-type opioid receptor	0	4	0	4
Carbonic anhydrase 5A, mitochondrial	0	5	1	10
Carbonic anhydrase	0	1	0	3
Kappa-type opioid receptor	0	2	0	3
Carbonic anhydrase 7	0	4	1	8
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	4	1	0	5
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	1	0	3
D(2) dopamine receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	16	4	1	21
Gamma-aminobutyric acid receptor subunit beta-3	16	3	1	20
Gamma-aminobutyric acid receptor subunit beta-2	16	3	1	20
Cholinesterase	0	3	0	3
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	3	0	3
Fatty-acid amide hydrolase 1	0	2	0	2
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	2	0	5
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Carbonic anhydrase 9	0	7	1	12
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	2	0	2
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Renin	0	1	0	1
Carbonic anhydrase	0	1	0	3
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	2	1	5
GABA theta subunit	16	3	1	20
Canalicular multispecific organic anion transporter 1	0	44	0	45
Carbonic anhydrase 4	0	2	0	3
Carbonic anhydrase 15	0	2	0	5
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	4	0	7
Carbonic anhydrase 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	16	3	1	20
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 14	0	5	1	10
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	4	1	9
Fumarate hydratase	20	0	0	20
AR protein	44	0	0	44
EWS/FLI fusion protein	39	0	0	39
polyprotein	20	0	0	20
histone acetyltransferase KAT2A isoform 1	14	0	0	14
Cellular tumor antigen p53	26	0	0	26
Hydroxycarboxylic acid receptor 2	0	0	1	1
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	13	0	0	13
Chain B, HADH2 protein	13	0	0	13
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
Chain A, Ferritin light chain	11	0	0	11
Thymidine kinase	0	2	0	2
phosphopantetheinyl transferase	19	0	0	19
GLS protein	17	0	0	17
TDP1 protein	47	0	0	47
Smad3	10	0	0	10
thyroid stimulating hormone receptor	17	0	0	17
activating transcription factor 6	10	0	0	10
Histone H2A.x	18	0	0	18
hemoglobin subunit beta	5	0	0	5
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
ubiquitin carboxyl-terminal hydrolase 2 isoform a	6	0	0	6
lamin isoform A-delta10	38	0	0	38
Solute carrier family 22 member 1	0	7	0	9
Bile salt export pump	0	9	0	9
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	3	0	6
POU domain, class 2, transcription factor 2	0	0	0	2
Cytochrome P450 2J2	0	12	0	12
Disintegrin and metalloproteinase domain-containing protein 17	4	0	0	4
Purine nucleoside phosphorylase	0	0	3	3
Solute carrier family 22 member 6	0	2	0	7
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	3	0	6
Thymidine kinase	0	2	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	19	0	0	19
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	1	6
Proton-coupled amino acid transporter 1	0	3	0	3
Adenosine deaminase	0	0	0	1
Chain A, farnesyl pyrophosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	4	0	5
Farnesyl pyrophosphate synthase	0	6	0	6
Acetylcholinesterase	0	6	0	7
Hypoxanthine-guanine phosphoribosyltransferase	0	2	0	2
Farnesyl pyrophosphate synthase	0	4	0	4
Farnesyl pyrophosphate synthase	0	2	0	2
estrogen nuclear receptor alpha	49	0	0	49
Aminoglycoside 3'-phosphotransferase	0	0	0	1
ATP-dependent phosphofructokinase	18	0	0	18
Chain A, Cruzipain	5	0	0	5
interleukin 8	4	0	0	4
farnesoid X nuclear receptor	22	0	0	22
peroxisome proliferator-activated receptor delta	19	0	0	19
vitamin D (1,25- dihydroxyvitamin D3) receptor	20	0	0	20
tumor necrosis factor	1	0	0	1
vitamin D3 receptor isoform VDRA	13	0	0	13
Nuclear receptor ROR-gamma	6	0	0	6
Potassium voltage-gated channel subfamily H member 2	0	17	0	18
Aurora kinase B	0	1	2	3
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	6	1	10
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, 2-oxoglutarate Oxygenase	15	0	0	15
Beta-lactamase	0	0	0	2
acid sphingomyelinase	3	0	0	3
apical membrane antigen 1, AMA1	4	0	0	4
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase type 2	0	0	1	4
Metallo-beta-lactamase VIM-11	0	0	0	3
Metallo-beta-lactamase VIM-2	0	0	0	3
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	13	0	0	13
chromobox protein homolog 1	25	0	0	25
thyroid hormone receptor beta isoform 2	31	0	0	31
DNA polymerase beta	2	0	0	2
DNA polymerase eta isoform 1	3	0	0	3
DNA polymerase iota isoform a (long)	21	0	0	21
DNA polymerase kappa isoform 1	10	0	0	10
60 kDa heat shock protein, mitochondrial	0	4	0	4
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	4	0	4
Solute carrier family 15 member 1	0	1	0	1
Spike glycoprotein	17	1	2	20
10 kDa heat shock protein, mitochondrial	0	4	0	4
Angiopoietin-1 receptor	0	0	2	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	2	0	2
Thiosulfate sulfurtransferase	0	4	0	4
Metallo-beta-lactamase VIM-13	0	0	0	3
Efflux transporter	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	0	0	2
Class D beta-lactamase	0	0	0	3
60 kDa chaperonin	0	4	0	4
Metallo-beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	3	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	1	4
10 kDa chaperonin	0	4	0	4
Metallo-b-lactamase	0	0	0	5
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	3
Histamine H3 receptor	0	0	0	2
Beta-lactamase class B VIM-2	0	0	1	6
Beta-lactamase VIM-1	0	0	0	3
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
NFKB1 protein, partial	9	0	0	9
alpha-galactosidase	5	0	0	5
cytochrome P450 2C19 precursor	5	0	0	5
flap endonuclease 1	9	0	0	9
muscarinic acetylcholine receptor M1	14	0	0	14
lethal factor (plasmid)	11	0	0	11
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
aldehyde dehydrogenase 1 family, member A1	23	0	0	23
hypothetical protein, conserved	3	0	0	3
cytochrome P450 2D6	14	0	0	14
glucocerebrosidase	5	0	0	5
Rac1 protein	0	0	1	1
IDH1	17	0	0	17
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	3	2	5
Fatty acid-binding protein, liver	0	5	2	7
Integrin beta-3	9	1	0	10
Myeloperoxidase	0	3	0	3
Prostaglandin G/H synthase 1	0	4	0	4
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	9	1	0	10
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	5	0	5
Substance-P receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	6	1	7
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	3	0	3
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	4	1	5
Sigma non-opioid intracellular receptor 1	0	1	2	3
regulator of G-protein signaling 4	13	0	0	13
Beta-1 adrenergic receptor	0	0	1	1
D(1A) dopamine receptor	4	0	0	4
Urease	0	1	0	1
Beta-2 adrenergic receptor	0	2	1	3
Beta-1 adrenergic receptor	0	2	1	3
Beta-3 adrenergic receptor	0	4	1	5
Alpha-1D adrenergic receptor	0	7	0	7
Alpha-1A adrenergic receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
TAR DNA-binding protein 43	7	1	0	8
Beta-2 adrenergic receptor	0	0	1	1
acetylcholinesterase	11	0	0	11
RAR-related orphan receptor gamma	31	0	0	31
SMAD family member 2	12	0	0	12
ATAD5 protein, partial	13	0	0	13
SMAD family member 3	12	0	0	12
Microtubule-associated protein tau	10	0	0	10
thioredoxin glutathione reductase	7	0	0	7
pregnane X nuclear receptor	30	0	0	30
G	22	0	0	22
P53	2	0	0	2
peroxisome proliferator activated receptor gamma	20	0	0	20
aryl hydrocarbon receptor	17	0	0	17
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	21	0	0	21
thyroid stimulating hormone receptor	15	0	0	15
v-jun sarcoma virus 17 oncogene homolog (avian)	17	0	0	17
peripheral myelin protein 22 isoform 1	13	0	0	13
cellular tumor antigen p53 isoform a	10	0	0	10
heat shock protein beta-1	9	0	0	9
cytochrome P450 3A4 isoform 1	16	0	0	16
M-phase phosphoprotein 8	13	0	0	13
Voltage-dependent calcium channel gamma-2 subunit	17	0	0	17
Interferon beta	34	0	0	34
HLA class I histocompatibility antigen, B alpha chain	22	0	0	22
Glutamate receptor 2	17	0	0	17
Inositol hexakisphosphate kinase 1	22	0	0	22
ATPase family AAA domain-containing protein 5	20	0	0	20
Ataxin-2	26	0	0	26
Protein-arginine deiminase type-4	0	5	0	5
cytochrome P450 2C9, partial	22	0	0	22
PPM1D protein	14	0	0	14
Bone morphogenetic protein receptor type-1B	0	0	2	2
Membrane-associated progesterone receptor component 1	0	0	2	2
Serine/threonine-protein kinase PLK4	0	0	2	2
ATP-dependent RNA helicase DDX3X	0	0	2	2
Pyridoxal kinase	0	0	2	2
Citron Rho-interacting kinase	0	0	2	2
Serine/threonine-protein kinase Chk1	0	1	3	4
Aurora kinase A	0	0	2	2
Cyclin-G-associated kinase	0	1	2	3
Ephrin type-B receptor 6	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 3	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	0	2	2
Dynamin-like 120 kDa protein, mitochondrial	0	0	2	2
Tyrosine-protein kinase JAK2	0	4	2	9
Eukaryotic translation initiation factor 5B	0	0	1	1
Rho-associated protein kinase 2	0	1	2	3
Serine/threonine-protein kinase ULK1	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	2	2
Ribosomal protein S6 kinase alpha-5	0	1	2	3
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	2	2
Ribosomal protein S6 kinase alpha-4	0	0	2	2
Serine/threonine-protein kinase 16	0	0	2	2
Serine/threonine-protein kinase 10	0	0	2	2
Serine/threonine-protein kinase D3	0	0	2	2
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	2	2
Serine/threonine-protein kinase LATS1	0	0	2	2
Serine/threonine-protein kinase PAK 4	0	0	2	2
Tyrosine-protein kinase ABL1	0	3	4	7
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	2	2
Protein kinase C beta type	0	1	2	3
Insulin receptor	0	1	2	3
Tyrosine-protein kinase Lck	0	1	2	3
Tyrosine-protein kinase Fyn	0	3	2	5
Cyclin-dependent kinase 1	0	0	2	2
Glycogen phosphorylase, liver form	0	0	2	2
Tyrosine-protein kinase Fes/Fps	0	0	2	2
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	0	2	2
Tyrosine-protein kinase Lyn	0	0	2	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	2	2
Insulin-like growth factor 1 receptor	0	0	2	2
Signal recognition particle receptor subunit alpha	0	0	2	2
Cytochrome c1, heme protein, mitochondrial	0	0	2	2
Hepatocyte growth factor receptor	0	0	2	2
Tyrosine-protein kinase HCK	0	0	2	2
Platelet-derived growth factor receptor beta	0	0	2	2
Serine/threonine-protein kinase A-Raf	0	0	2	2
Glycogen phosphorylase, brain form	0	0	2	2
Breakpoint cluster region protein	0	0	3	3
Serine/threonine-protein kinase pim-1	0	0	2	2
Fibroblast growth factor receptor 1	0	0	2	2
DNA topoisomerase 2-alpha	0	4	3	17
Cyclin-dependent kinase 4	0	0	2	2
ADP/ATP translocase 3	0	0	2	2
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	2	2	4
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	2	2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	2	2
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	2	4
Tyrosine-protein kinase Fer	0	0	2	2
Protein kinase C alpha type	0	1	2	3
cAMP-dependent protein kinase catalytic subunit alpha	0	0	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	2	2
Casein kinase II subunit alpha'	0	1	2	3
Ras-related protein Rab-6A	0	0	2	2
Ephrin type-A receptor 1	0	0	2	2
Multifunctional protein ADE2	0	0	2	2
cAMP-dependent protein kinase catalytic subunit gamma	0	0	2	2
cAMP-dependent protein kinase catalytic subunit beta	0	0	2	2
Ferrochelatase, mitochondrial	0	0	2	2
Ribosomal protein S6 kinase beta-1	0	1	2	3
Tyrosine-protein kinase JAK1	0	4	3	10
Cyclin-dependent kinase 2	0	1	3	4
Beta-adrenergic receptor kinase 1	0	0	2	2
Probable ATP-dependent RNA helicase DDX6	0	0	2	2
Mitogen-activated protein kinase 3	0	0	2	2
MAP/microtubule affinity-regulating kinase 3	0	0	2	2
Deoxycytidine kinase	0	0	2	4
Mitogen-activated protein kinase 1	0	1	2	3
Ephrin type-A receptor 2	0	0	2	2
Ephrin type-B receptor 2	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	4	3	10
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	2	2
Heme oxygenase 2	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	2	2
DnaJ homolog subfamily A member 1	0	0	2	2
RAC-alpha serine/threonine-protein kinase	0	1	2	3
RAC-beta serine/threonine-protein kinase	0	0	2	2
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	0	2	2
Receptor-type tyrosine-protein kinase FLT3	0	0	2	2
Bone morphogenetic protein receptor type-1A	0	0	2	2
Activin receptor type-1B	0	0	2	2
TGF-beta receptor type-1	0	0	2	2
Serine/threonine-protein kinase receptor R3	0	0	2	2
TGF-beta receptor type-2	0	0	2	2
Electron transfer flavoprotein subunit beta	0	0	1	1
Tyrosine-protein kinase CSK	0	1	2	3
Glycine--tRNA ligase	0	0	2	2
Protein kinase C iota type	0	0	2	2
Exosome RNA helicase MTR4	0	0	2	2
Tyrosine-protein kinase Tec	0	1	2	3
Tyrosine-protein kinase ABL2	0	0	2	2
Tyrosine-protein kinase FRK	0	0	2	2
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase SYK	0	0	2	2
26S proteasome regulatory subunit 6B	0	0	2	2
Mitogen-activated protein kinase 8	0	1	2	3
Mitogen-activated protein kinase 9	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 3	0	0	2	2
Casein kinase I isoform alpha	0	0	2	2
Casein kinase I isoform delta	0	0	2	2
MAP kinase-activated protein kinase 2	0	1	2	3
Elongation factor Tu, mitochondrial	0	0	2	2
Cysteine--tRNA ligase, cytoplasmic	0	0	2	2
Casein kinase I isoform epsilon	0	0	2	2
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	2	2
Dual specificity protein kinase CLK1	0	0	2	2
Dual specificity protein kinase CLK2	0	0	2	2
Dual specificity protein kinase CLK3	0	0	2	2
Cyclin-dependent kinase 7	0	0	2	2
Cyclin-dependent kinase 9	0	0	2	2
Ras-related protein Rab-27A	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	2	2
Ribosomal protein S6 kinase alpha-3	0	1	2	3
Serine/threonine-protein kinase Nek2	0	0	2	2
Serine/threonine-protein kinase Nek3	0	0	2	2
Tyrosine-protein kinase JAK3	0	4	2	10
Dual specificity mitogen-activated protein kinase kinase 6	0	0	2	2
LIM domain kinase 1	0	0	2	2
LIM domain kinase 2	0	0	2	2
Mitogen-activated protein kinase 10	0	0	2	2
Tyrosine--tRNA ligase, cytoplasmic	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	3
Ephrin type-B receptor 3	0	0	2	2
Ephrin type-A receptor 5	0	0	2	2
Ephrin type-B receptor 4	0	0	2	2
Ephrin type-A receptor 4	0	0	2	2
Adenylate kinase 2, mitochondrial	0	0	2	2
Adenosine kinase	0	0	2	2
Ras-related protein Rab-10	0	0	2	2
Actin-related protein 3	0	0	2	2
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	2	2
Casein kinase I isoform gamma-2	0	0	2	2
Cyclin-dependent kinase 3	0	0	2	2
Cyclin-dependent kinase 6	0	0	2	2
Cyclin-dependent-like kinase 5	0	1	2	3
Cyclin-dependent kinase 16	0	0	2	2
Cyclin-dependent kinase 17	0	0	2	2
ATP-dependent 6-phosphofructokinase, platelet type	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 1	0	0	2	2
DNA topoisomerase 2-beta	0	1	3	12
Protein kinase C theta type	0	0	2	2
Activin receptor type-1	0	0	2	2
Macrophage-stimulating protein receptor	0	0	2	2
Focal adhesion kinase 1	0	0	2	2
Protein kinase C delta type	0	0	2	2
Tyrosine-protein kinase BTK	0	2	2	4
Activated CDC42 kinase 1	0	0	2	2
Epithelial discoidin domain-containing receptor 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	2	2
Serine/threonine-protein kinase 4	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	3
Dual specificity mitogen-activated protein kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase 7	0	0	2	2
Serine/threonine-protein kinase PAK 2	0	0	2	2
Serine/threonine-protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 1	0	0	2	2
Integrin-linked protein kinase	0	0	2	2
Rho-associated protein kinase 1	0	0	2	2
Non-receptor tyrosine-protein kinase TNK1	0	0	2	2
Serine/threonine-protein kinase ATR	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	2	2
Activin receptor type-2B	0	0	2	2
Bone morphogenetic protein receptor type-2	0	0	2	2
Protein-tyrosine kinase 6	0	0	2	2
cGMP-dependent protein kinase 1	0	0	2	2
Cyclin-dependent kinase 13	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	2	2
Protein-tyrosine kinase 2-beta	0	0	2	2
Maternal embryonic leucine zipper kinase	0	0	2	2
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Ephrin type-A receptor 7	0	0	2	2
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	2	2
Dual specificity testis-specific protein kinase 1	0	0	2	2
Myosin light chain kinase, smooth muscle	0	0	2	2
Mitogen-activated protein kinase 11	0	1	2	3
Serine/threonine-protein kinase STK11	0	0	2	2
Serine/threonine-protein kinase N1	0	0	2	2
Serine/threonine-protein kinase N2	0	0	2	2
Mitogen-activated protein kinase 14	0	1	2	3
Calcium/calmodulin-dependent protein kinase type IV	0	0	2	2
Mitogen-activated protein kinase kinase kinase 11	0	0	2	2
MAP kinase-activated protein kinase 3	0	0	1	1
Discoidin domain-containing receptor 2	0	0	2	2
AP2-associated protein kinase 1	0	1	2	3
Myosin light chain kinase 3	0	0	2	2
Uncharacterized aarF domain-containing protein kinase 5	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	2	2
Rab-like protein 3	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	2	2
Serine/threonine-protein kinase MRCK gamma	0	0	2	2
Acyl-CoA dehydrogenase family member 10	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	2	2
Uncharacterized protein FLJ45252	0	0	2	2
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	2	2
Serine/threonine-protein kinase MARK2	0	0	2	2
ATP-dependent RNA helicase DHX30	0	0	2	2
Serine/threonine-protein kinase TAO1	0	0	2	2
STE20-related kinase adapter protein alpha	0	0	2	2
Myosin-14	0	0	2	2
AarF domain-containing protein kinase 1	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	2	2
MAP kinase-activated protein kinase 5	0	1	2	3
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
Misshapen-like kinase 1	0	0	2	2
Atypical kinase COQ8A, mitochondrial	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	2	2
Mitogen-activated protein kinase 15	0	0	2	2
Serine/threonine-protein kinase Nek9	0	0	2	2
ATP-dependent RNA helicase DDX1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1G	0	0	2	2
Serine/threonine-protein kinase Nek1	0	0	2	2
PAS domain-containing serine/threonine-protein kinase	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	2	2
EKC/KEOPS complex subunit TP53RK	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	2	2
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	2	2
Nucleolar GTP-binding protein 1	0	0	2	2
Serine/threonine-protein kinase D2	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	2	2
RNA cytidine acetyltransferase	0	0	2	2
Serine/threonine-protein kinase SIK2	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO3	0	0	2	2
dCTP pyrophosphatase 1	0	0	2	2
Dual specificity protein kinase CLK4	0	0	2	2
Casein kinase I isoform gamma-1	0	0	2	2
Serine/threonine-protein kinase PAK 6	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	2	2
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
BMP-2-inducible protein kinase	0	0	2	2
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	2	2
Interleukin-1 receptor-associated kinase 4	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	0	2	2
Cyclin-dependent kinase 12	0	0	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	2	2
Serine/threonine-protein kinase 26	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	2	2
Serine/threonine-protein kinase NLK	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	2	3
Serine/threonine-protein kinase TBK1	0	1	2	3
Septin-9	0	0	2	2
Ribosomal protein S6 kinase alpha-6	0	0	2	2
TRAF2 and NCK-interacting protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	2	2
Long-chain-fatty-acid--CoA ligase 5	0	0	2	2
Serine/threonine-protein kinase ICK	0	0	2	2
RAC-gamma serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase 38-like	0	0	2	2
Serine/threonine-protein kinase SIK3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 2	0	0	2	2
Thyroid hormone receptor-associated protein 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 3	0	0	2	2
Serine/threonine-protein kinase MRCK beta	0	0	2	2
Interleukin-1 receptor-associated kinase 3	0	0	2	2
Serine/threonine-protein kinase 24	0	0	2	2
Casein kinase I isoform gamma-3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 4	0	0	2	2
progesterone receptor	21	0	0	21
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
USP1 protein, partial	17	0	0	17
caspase-1 isoform alpha precursor	2	0	0	2
Caspase-7	2	0	0	2
Inositol monophosphatase 1	7	0	0	7
Solute carrier organic anion transporter family member 1B3	0	10	0	12
Solute carrier organic anion transporter family member 1B1	0	8	0	9
DNA topoisomerase	0	1	0	1
15-lipoxygenase, partial	4	0	0	4
Thrombopoietin	5	0	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	15	0	0	15
67.9K protein	13	0	0	13
putative alpha-glucosidase	1	0	0	1
lysosomal alpha-glucosidase preproprotein	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 2	16	0	0	16
huntingtin isoform 2	7	0	0	7
ras-related protein Rab-9A	5	0	0	5
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	8	0	0	8
nuclear receptor ROR-gamma isoform 1	12	0	0	12
relaxin receptor 1 isoform 1	3	0	0	3
Telomerase reverse transcriptase	0	1	0	1
Histone deacetylase 3	0	1	0	1
Type-2 restriction enzyme ScaI	0	1	0	1
Deoxyribonuclease-2-alpha	0	1	0	1
Tyrosyl-DNA phosphodiesterase 2	0	1	0	1
Deoxyribonuclease-1	0	1	0	1
Type-2 restriction enzyme PstI	0	1	0	1
Type-2 restriction enzyme EcoRI	0	1	0	1
Prothrombin	0	0	0	2
DNA ligase	0	2	0	2
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
DNA topoisomerase 1	0	2	1	9
Type-2 restriction enzyme BamHI	0	1	0	1
Somatostatin receptor type 1	0	1	0	1
Somatostatin receptor type 2	0	1	0	1
Somatostatin receptor type 4	0	1	0	1
Somatostatin receptor type 3	0	1	0	1
Somatostatin receptor type 5	0	1	0	1
5-hydroxytryptamine receptor 2B	0	6	0	6
Type-2 restriction enzyme HindIII	0	1	0	1
Histone deacetylase 4	0	1	0	1
Ribonuclease pancreatic	0	1	0	1
DNA topoisomerase 1	0	1	0	2
Histone deacetylase 1	0	2	0	2
DNA topoisomerase 1	0	1	0	1
Integrase	0	4	0	4
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
DNA topoisomerase type IB small subunit	0	0	1	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	2	0	2
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
mitogen-activated protein kinase 1	8	0	0	8
Vpr	3	0	0	3
Albumin	0	0	2	2
Major prion protein	0	0	3	3
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	0	0	4
Sodium channel protein type 4 subunit alpha	0	3	0	6
Sodium channel protein type 9 subunit alpha	0	4	0	4
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	3
estrogen receptor 2 (ER beta)	11	0	0	11
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
Luciferase	12	0	0	12
caspase 7, apoptosis-related cysteine protease	7	0	0	7
bromodomain adjacent to zinc finger domain 2B	9	0	0	9
caspase-3	7	0	0	7
potassium voltage-gated channel subfamily H member 2 isoform d	9	0	0	9
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
urokinase-type plasminogen activator precursor	11	0	0	11
plasminogen precursor	11	0	0	11
urokinase plasminogen activator surface receptor precursor	11	0	0	11
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	1	2	3
Replicase polyprotein 1ab	0	1	3	4
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	1	2	3
Dihydrofolate reductase	0	3	0	3
Riboflavin-binding protein	0	1	2	3
Amyloid-beta precursor protein	1	1	0	3
Histidine-rich protein PFHRP-II	0	3	0	4
Procathepsin L	0	1	2	3
Muscarinic acetylcholine receptor M2	0	9	0	9
Muscarinic acetylcholine receptor M4	0	10	0	10
Muscarinic acetylcholine receptor M5	0	6	0	6
Alpha-2A adrenergic receptor	0	11	0	11
Replicase polyprotein 1a	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
Replicase polyprotein 1ab	0	2	2	4
Spike glycoprotein	0	1	0	1
Replicase polyprotein 1ab	0	3	2	5
Muscarinic acetylcholine receptor M1	0	8	0	8
Alpha-2B adrenergic receptor	0	8	0	8
Alpha-2C adrenergic receptor	0	10	0	10
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	8	0	8
Serine/threonine-protein kinase mTOR	0	2	1	3
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Beta-secretase 1	0	1	0	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Phosphoethanolamine N-methyltransferase	0	2	0	2
Angiotensin-converting enzyme 2	0	1	2	3
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
cytochrome P450 2C9 precursor	8	0	0	8
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	2	0	4
DNA gyrase subunit B	0	2	0	4
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
DNA gyrase subunit A	0	1	0	2
Multidrug resistance protein MdtK	0	0	1	1
Histamine H2 receptor	13	0	0	13
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	3
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
glp-1 receptor, partial	14	0	0	14
tyrosine-protein kinase Yes	4	0	0	4
bcl-2-like protein 11 isoform 1	0	0	1	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Adenosine receptor A3	0	2	0	2
Rap guanine nucleotide exchange factor 4	2	0	0	2
5-hydroxytryptamine receptor 4	0	8	2	10
Muscarinic acetylcholine receptor M1	0	1	3	4
Muscarinic acetylcholine receptor M3	0	1	3	4
Muscarinic acetylcholine receptor M4	0	1	3	4
Muscarinic acetylcholine receptor M5	0	1	3	4
Muscarinic acetylcholine receptor M2	0	1	3	4
Peroxisome proliferator-activated receptor alpha	0	1	3	4
Peroxisome proliferator-activated receptor gamma	0	3	4	8
Peroxisome proliferator-activated receptor gamma	0	0	3	3
Peroxisome proliferator-activated receptor alpha	0	3	3	6
endonuclease IV	7	0	0	7
dopamine D1 receptor	4	0	0	4
pregnane X receptor	4	0	0	4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	7	0	0	7
Glucocorticoid receptor	0	13	2	20
Sex hormone-binding globulin	0	0	2	2
Glycine receptor subunit alpha-1	0	12	0	12
Corticosteroid-binding globulin	0	2	0	2
Glycine receptor subunit beta	0	12	0	12
Glycine receptor subunit alpha-2	0	12	0	12
Glycine receptor subunit alpha-3	0	12	0	12
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	5	0	5
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	3	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
transactivating tegument protein VP16 [Human herpesvirus 1]	0	4	0	4
nuclear receptor coactivator 3 isoform a	0	3	0	3
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	2	0	3
Thymidine kinase	0	1	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
hypoxia-inducible factor 1 alpha subunit	9	0	0	9
nuclear receptor subfamily 1, group I, member 2	9	0	0	9
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
Rap guanine nucleotide exchange factor 3	2	0	0	2
Estrogen receptor	0	4	0	4
Aldo-keto reductase family 1 member B1	0	12	0	12
Adenosine receptor A3	0	4	0	4
Alpha-1B adrenergic receptor	0	5	0	5
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	4	0	4
Sodium-dependent noradrenaline transporter	0	12	0	12
5-hydroxytryptamine receptor 2A	0	10	0	10
Mu-type opioid receptor	0	2	0	2
D(3) dopamine receptor	0	10	0	10
Kappa-type opioid receptor	0	2	0	2
Alpha-1A adrenergic receptor	0	5	0	5
Sodium-dependent dopamine transporter	0	8	0	8
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Caspase-7	3	0	0	3
runt-related transcription factor 1 isoform AML1b	1	0	0	1
caspase-3	3	0	0	3
core-binding factor subunit beta isoform 2	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	5	0	0	5
Transthyretin	0	1	0	1
NADH-ubiquinone oxidoreductase chain 4	0	0	0	1
ATP-dependent translocase ABCB1	0	11	3	24
72 kDa type IV collagenase	0	2	0	2
Carbonyl reductase [NADPH] 1	0	0	0	1
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Platelet-activating factor receptor	1	0	0	1
Multidrug resistance-associated protein 1	0	5	1	9
Reverse transcriptase/RNaseH	0	3	3	9
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	1	1	2
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Genome polyprotein	0	1	0	1
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
serine/threonine-protein kinase PLK1	4	0	0	4
streptokinase A precursor	0	0	3	3
Motilin receptor	0	1	1	2
30S ribosomal protein S6	0	1	1	2
30S ribosomal protein S7	0	1	1	2
50S ribosomal protein L15	0	1	1	2
Albumin	0	2	7	9
ATP-dependent translocase ABCB1	0	4	0	4
60 kDa chaperonin	0	2	0	2
50S ribosomal protein L10	0	1	1	2
50S ribosomal protein L11	0	1	1	2
50S ribosomal protein L7/L12	0	1	1	2
50S ribosomal protein L19	0	1	1	2
50S ribosomal protein L1	0	1	1	2
50S ribosomal protein L20	0	1	1	2
50S ribosomal protein L27	0	1	1	2
50S ribosomal protein L28	0	1	1	2
50S ribosomal protein L29	0	1	1	2
50S ribosomal protein L31	0	1	1	2
50S ribosomal protein L31 type B	0	1	1	2
50S ribosomal protein L32	0	1	1	2
50S ribosomal protein L33	0	1	1	2
50S ribosomal protein L34	0	1	1	2
50S ribosomal protein L35	0	1	1	2
50S ribosomal protein L36	0	1	1	2
30S ribosomal protein S10	0	1	1	2
30S ribosomal protein S11	0	1	1	2
30S ribosomal protein S12	0	1	1	2
30S ribosomal protein S13	0	1	1	2
30S ribosomal protein S16	0	1	1	2
30S ribosomal protein S18	0	1	1	2
30S ribosomal protein S19	0	1	1	2
30S ribosomal protein S20	0	1	1	2
30S ribosomal protein S2	0	1	1	2
30S ribosomal protein S3	0	1	1	2
30S ribosomal protein S4	0	1	1	2
30S ribosomal protein S5	0	1	1	2
30S ribosomal protein S8	0	1	1	2
30S ribosomal protein S9	0	1	1	2
50S ribosomal protein L13	0	1	1	2
50S ribosomal protein L14	0	1	1	2
50S ribosomal protein L16	0	1	1	2
50S ribosomal protein L23	0	1	1	2
30S ribosomal protein S15	0	1	1	2
50S ribosomal protein L17	0	1	1	2
50S ribosomal protein L21	0	1	1	2
50S ribosomal protein L30	0	1	1	2
50S ribosomal protein L6	0	1	1	2
30S ribosomal protein S14	0	1	1	2
30S ribosomal protein S17	0	1	1	2
30S ribosomal protein S1	0	1	1	2
50S ribosomal protein L18	0	1	1	2
Chitinase B	0	1	0	1
ATP-dependent translocase ABCB1	0	4	0	5
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
50S ribosomal protein L2	0	1	1	2
50S ribosomal protein L3	0	1	1	2
50S ribosomal protein L24	0	1	1	2
50S ribosomal protein L4	0	1	1	2
50S ribosomal protein L22	0	1	1	2
50S ribosomal protein L5	0	1	1	2
30S ribosomal protein S21	0	1	1	2
50S ribosomal protein L25	0	1	1	2
Cytochrome P450 1B1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
50S ribosomal protein L36 2	0	1	1	2
Regulatory protein E2	0	0	2	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
DNA topoisomerase 2	0	0	0	2
UDP-glucuronosyltransferase 1A1	0	0	0	1
Caspase-3	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	0	0	3
Glutamate receptor ionotropic, NMDA 2C	0	0	0	3
DNA topoisomerase 2-alpha	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	0	0	3
Tubulin beta-2B chain	0	2	0	2
Similar to alpha-tubulin isoform 1	0	2	0	2
Similar to alpha-tubulin isoform 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	0	0	3
Glutamate receptor ionotropic, NMDA 3A	0	0	0	3
Chain A, JmjC domain-containing histone demethylation protein 3A	6	0	0	6
nonstructural protein 1	6	0	0	6
serine-protein kinase ATM isoform a	1	0	0	1
neuropeptide S receptor isoform A	4	0	0	4
Fatty acid-binding protein, liver	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	1	2
Cruzipain	0	1	0	1
5-hydroxytryptamine receptor 2C	0	8	0	8
Peroxisome proliferator-activated receptor alpha	0	0	1	1
corticotropin-releasing hormone receptor 2	0	1	1	2
corticotropin releasing factor-binding protein	0	1	1	2
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
5'-nucleotidase	0	1	0	1
Adenosine deaminase	0	0	0	2
Chain A, probable fosfomycin resistance protein	0	0	1	1
Chain B, probable fosfomycin resistance protein	0	0	1	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
DNA polymerase delta catalytic subunit	0	1	0	1
cytochrome P450 2D6 isoform 1	5	0	0	5
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 2	0	4	0	5
Coagulation factor X	0	1	0	1
Plasminogen	0	2	0	2
Coagulation factor XII	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Tissue-type plasminogen activator	0	1	0	1
Serine protease hepsin	0	1	0	1
Multidrug and toxin extrusion protein 2	0	3	0	3
ClpP	3	0	0	3
Transitional endoplasmic reticulum ATPase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	3
Hsf1 protein	0	0	1	1
Guanine nucleotide-binding protein G	4	0	0	4
Genome polyprotein	0	1	0	1
Cyclic GMP-AMP synthase	0	2	0	2
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
DNA repair protein RAD52 homolog isoform a	0	0	0	2
Mast/stem cell growth factor receptor Kit	0	1	2	3
Platelet-derived growth factor receptor alpha	0	1	2	3
Cytochrome P450 3A5	0	1	1	3
Chain A, Acetylcholinesterase	0	1	0	1
interferon gamma precursor	0	0	0	2
Solute carrier family 22 member 3	0	2	0	2
Interstitial collagenase	0	2	0	2
Acetylcholinesterase	0	1	0	1
Liver carboxylesterase 1	0	0	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Polyphenol oxidase 2	0	2	0	3
Formamidopyrimidine-DNA glycosylase	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
Dihydrofolate reductase	0	4	2	6
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Sodium channel protein type 5 subunit alpha	0	3	0	3
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sodium channel protein type 10 subunit alpha	0	1	0	1
matrix metalloproteinase 1, partial	0	0	1	1
Parkin	3	0	0	3
pyruvate kinase	2	0	0	2
NPC intracellular cholesterol transporter 1 precursor	4	0	0	4
histone deacetylase 9 isoform 3	4	0	0	4
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Amine oxidase [flavin-containing] A	0	3	0	3
Endothelin receptor type B	1	0	0	1
Endothelin-1 receptor	1	0	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	3	0	3
Methionine aminopeptidase	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	1	2
Calmodulin-domain protein kinase 1	0	1	0	1
importin subunit beta-1 isoform 1	4	0	0	4
snurportin-1	4	0	0	4
Large neutral amino acids transporter small subunit 1	0	2	0	2
transcriptional regulator ERG isoform 3	3	0	0	3
UDP-glucose 6-dehydrogenase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	3
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-19	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase TEM	0	1	0	3
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase IMP-1	0	0	0	2
BlaVIM-1	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	5	0	6
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	3	0	3
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	2
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Solute carrier family 22 member 11	0	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Stromelysin-1	0	2	1	3
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Matrix metalloproteinase-9	0	2	0	2
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Serine/threonine-protein kinase Chk2	0	1	1	2
S-adenosylmethionine decarboxylase proenzyme	0	1	0	1
S-adenosylmethionine decarboxylase proenzyme	0	1	0	1
Chain A, Probable serine/threonine-protein kinase pknB	0	1	0	1
WRN	1	0	0	1
DNA polymerase III, partial	2	0	0	2
nonstructural protein 1	0	1	0	1
LANA	0	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
phospholipase A2, group III	0	1	0	1
histone-lysine N-methyltransferase NSD2 isoform 1	0	0	0	1
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
protein AF-9 isoform a	0	0	0	1
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	1
rac GTPase-activating protein 1 isoform a	0	1	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Receptor tyrosine-protein kinase erbB-2	0	2	1	3
Proto-oncogene tyrosine-protein kinase ROS	0	1	1	2
Ornithine decarboxylase	1	0	0	1
Angiotensin-converting enzyme	0	4	0	4
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	1	1	2
NEDD8-activating enzyme E1 regulatory subunit	0	0	1	1
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
Casein kinase II subunit alpha 3	0	1	0	1
NEDD8-activating enzyme E1 catalytic subunit	0	0	1	1
Single-stranded DNA cytosine deaminase	1	0	0	1
P2Y purinoceptor 12	0	1	0	1
phosphoglycerate kinase	1	0	0	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	2	0	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	3
Hormone-sensitive lipase	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Caspase-1	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	2
Aldo-keto reductase family 1 member C3	0	1	0	1
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Caspase-9	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	2
Chain A, ARGINASE 1	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Chain A, ARGINASE 1	0	1	0	1
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Plasma kallikrein	0	0	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	3	0	4
SLC16A10 protein	0	0	0	2
Carbonic anhydrase-like protein, putative	0	0	0	2
Monocarboxylate transporter 10	0	0	0	2
Phospholipase A-2-activating protein	0	2	0	2
beta-2 adrenergic receptor	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Gamma-aminobutyric acid	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Chain A, Alkaline Phosphatase	0	1	0	1
Chain A, ALKALINE PHOSPHATASE	0	1	0	1
Fe(3+)-Zn(2+) purple acid phosphatase	0	1	0	1
PAX8	0	0	0	1
nuclear receptor subfamily 0 group B member 1	0	1	0	1
steroidogenic factor 1	0	1	0	1
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Regulatory protein E2	0	0	1	1
Regulatory protein E2	0	0	1	1
Tubulin beta-4A chain	0	1	1	3
Tubulin beta chain	0	1	1	3
Tubulin alpha-3C chain	0	1	1	3
Tubulin alpha-1B chain	0	1	1	3
Tubulin alpha-4A chain	0	1	1	3
Tubulin beta-4B chain	0	1	1	3
Prostaglandin G/H synthase 2	0	1	0	1
Tubulin beta-3 chain	0	1	1	3
Tubulin beta-2A chain	0	1	1	3
Tubulin beta-8 chain	0	1	1	3
Calcium-activated potassium channel subunit alpha-1	0	1	0	1
Tubulin alpha-3E chain	0	1	1	3
Tubulin alpha-1A chain	0	1	1	3
Tubulin alpha-1C chain	0	1	1	3
Tubulin beta-6 chain	0	1	1	3
Tubulin beta-2B chain	0	1	1	3
Tubulin beta-1 chain	0	1	1	3
luciferase	0	0	0	1
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	2	2
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
Amine oxidase [flavin-containing] B	0	3	0	3
Serine hydroxymethyltransferase, mitochondrial	0	1	0	1
Chloroquine resistance transporter	0	2	0	2
Mcl-1	0	1	0	1
Snq2p	0	0	0	1
neutrophil cytosol factor 1	0	1	0	1
D(2) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
Histamine H1 receptor	0	2	0	2
5-hydroxytryptamine receptor 6	0	2	0	2
5-hydroxytryptamine receptor 7	0	3	0	3
Glutamate 5-kinase	0	0	0	1
Angiotensin-converting enzyme	0	1	0	1
Neutral amino acid transporter A	0	2	0	2
Neutral amino acid transporter B(0)	0	2	0	2
Amino acid transporter	0	2	0	2
heat shock protein 90, putative	0	0	0	1
N	0	1	0	1
NPYLR7B	0	0	1	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
tumor susceptibility gene 101 protein	1	0	0	1
Major prion protein	0	1	0	1
DNA-directed RNA polymerase subunit alpha	0	1	0	1
DNA-directed RNA polymerase subunit omega	0	1	0	1
DNA-directed RNA polymerase subunit beta'	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Acidic phospholipase A2 2	0	1	0	1
Histamine H2 receptor	0	4	0	4
Trypanothione reductase	0	2	0	2
Aldehyde oxidase 1	0	1	0	1
Aldehyde oxidase	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier family 22 member 1	0	2	0	3
Cytochrome P450 2D4	0	1	0	1
Solute carrier family 22 member 2	0	2	0	2
CDGSH iron-sulfur domain-containing protein 1	0	1	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
Free fatty acid receptor 1	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	0	1	1
Glutamate receptor ionotropic, NMDA 3B	0	0	1	1
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	4
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Catechol O-methyltransferase	0	0	1	1
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Thromboxane-A synthase	0	2	0	2
C-C chemokine receptor type 2	0	1	0	1
Cannabinoid receptor 2	0	0	1	1
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
Peroxisome proliferator-activated receptor delta	0	2	1	3
Glutamate receptor ionotropic, NMDA 1	0	0	1	1
ATP-binding cassette sub-family C member 8	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	1	1
Glutamate receptor ionotropic, NMDA 2B	0	0	1	1
ATP-sensitive inward rectifier potassium channel 11	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	1	1
Sodium/bile acid cotransporter	0	2	0	2
Thrombin	0	0	1	1
CDGSH iron-sulfur domain-containing protein 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	0	1	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	1	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	2
Xanthine dehydrogenase/oxidase	0	1	0	1
Solute carrier family 22 member 7	0	0	0	2
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Acetylcholinesterase	0	1	0	1
Pyruvate kinase PKM	0	0	1	1
PINK1	1	0	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Chain A, Glutathione S-transferase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Tumor necrosis factor	0	0	1	1
Fibroblast growth factor 1	0	0	1	1
Flavin reductase (NADPH)	0	0	1	1
Cystine/glutamate transporter	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Cereblon isoform 4	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	2	1	4
Cytochrome P450 2B1	0	1	0	1
Chain A, Tyrosine-protein kinase	0	1	0	1
Chain A, Tyrosine-protein kinase	0	1	0	1
Chain A, Tyrosine-protein kinase JAK2	0	1	0	1
Leukotriene C4 synthase	0	0	1	1
Serine/threonine-protein kinase Sgk1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	0	1	1
Serine/threonine-protein kinase 25	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	1	1
Serine/threonine-protein kinase RIO3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 7	0	1	1	2
Peripheral plasma membrane protein CASK	0	0	1	1
Serine/threonine-protein kinase DCLK1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	1	1
Muscle, skeletal receptor tyrosine-protein kinase	0	0	1	1
Mitogen-activated protein kinase 13	0	1	1	2
3-phosphoinositide-dependent protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 13	0	0	1	1
Death-associated protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
NUAK family SNF1-like kinase 1	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	1	1
Serine/threonine-protein kinase PAK 3	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Serine/threonine-protein kinase 17B	0	0	1	1
Cyclin-dependent kinase 14	0	0	1	1
Serine/threonine-protein kinase OSR1	0	0	1	1
RAF proto-oncogene serine/threonine-protein kinase	0	0	1	1
High affinity nerve growth factor receptor	0	0	1	1
Macrophage colony-stimulating factor 1 receptor	0	0	1	1
Tyrosine-protein kinase Fgr	0	0	1	1
Wee1-like protein kinase 2	0	0	1	1
Uncharacterized serine/threonine-protein kinase SBK3	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Insulin receptor-related protein	0	0	1	1
Vascular endothelial growth factor receptor 1	0	0	1	1
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	1	1
Serine/threonine-protein kinase MAK	0	0	1	1
Cyclin-dependent kinase 11B	0	0	1	1
Fibroblast growth factor receptor 2	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	0	1	1
Fibroblast growth factor receptor 4	0	0	1	1
Fibroblast growth factor receptor 3	0	0	1	1
Protein kinase C eta type	0	0	1	1
Activin receptor type-2A	0	0	1	1
Ephrin type-A receptor 3	0	0	1	1
Ephrin type-A receptor 8	0	0	1	1
Leukocyte tyrosine kinase receptor	0	0	1	1
Tyrosine-protein kinase receptor UFO	0	0	1	1
Mitogen-activated protein kinase 4	0	0	1	1
G protein-coupled receptor kinase 4	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
Tyrosine-protein kinase receptor Tie-1	0	0	1	1
Vascular endothelial growth factor receptor 3	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	0	1	1
Megakaryocyte-associated tyrosine-protein kinase	0	0	1	1
Tyrosine-protein kinase TXK	0	1	1	2
Tyrosine-protein kinase ZAP-70	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	0	1	1
Cyclin-dependent kinase 8	0	0	1	1
Tyrosine-protein kinase Blk	0	1	1	2
Cytoplasmic tyrosine-protein kinase BMX	0	1	1	2
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek4	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
Death-associated protein kinase 1	0	0	1	1
Mitogen-activated protein kinase 12	0	1	1	2
Ephrin type-B receptor 1	0	0	1	1
Hormonally up-regulated neu tumor-associated kinase	0	0	1	1
Serine/threonine-protein kinase SIK1	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 4	0	0	1	1
Cell division control protein 2 homolog	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
Tubulin alpha-1A chain	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	1	1
SRSF protein kinase 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 9	0	0	1	1
Serine/threonine-protein kinase PknB	0	0	1	1
Cyclin-dependent kinase-like 1	0	0	1	1
Protein kinase C epsilon type	0	1	1	2
Mitogen-activated protein kinase kinase kinase 10	0	0	1	1
Tyrosine-protein kinase receptor TYRO3	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Tyrosine-protein kinase ITK/TSK	0	1	1	2
Myotonin-protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 12	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Serine/threonine-protein kinase PAK 1	0	0	1	1
cGMP-dependent protein kinase 2	0	0	1	1
Serine/threonine-protein kinase PRP4 homolog	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1	0	0	1	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
Serine/threonine-protein kinase D1	0	0	1	1
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	1	1	2
Ribosomal protein S6 kinase alpha-2	0	0	1	1
Rhodopsin kinase GRK1	0	0	1	1
NT-3 growth factor receptor	0	0	1	1
BDNF/NT-3 growth factors receptor	0	0	1	1
Mitogen-activated protein kinase 6	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 19	0	0	1	1
Serine/threonine-protein kinase TNNI3K	0	0	1	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	0	1	1
Tyrosine-protein kinase JAK3	0	1	0	1
Tyrosine-protein kinase JAK2	0	1	0	1
Tyrosine-protein kinase JAK3	0	1	0	1
Serine/threonine-protein kinase Nek5	0	0	1	1
Dual serine/threonine and tyrosine protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 15	0	0	1	1
Serine/threonine-protein kinase tousled-like 2	0	0	1	1
Serine/threonine-protein kinase 32C	0	0	1	1
Serine/threonine-protein kinase pim-3	0	0	1	1
Serine/threonine-protein kinase VRK2	0	0	1	1
Myosin light chain kinase family member 4	0	0	1	1
Homeodomain-interacting protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1D	0	0	1	1
Cyclin-dependent kinase-like 3	0	0	1	1
Serine/threonine-protein kinase BRSK2	0	0	1	1
Serine/threonine-protein kinase NIM1	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	1	1
Serine/threonine-protein kinase DCLK2	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	1	1
Casein kinase I isoform alpha-like	0	0	1	1
Homeodomain-interacting protein kinase 4	0	0	1	1
Myosin-IIIa	0	0	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	1	1
Serine/threonine-protein kinase Nek11	0	0	1	1
Serine/threonine-protein kinase BRSK1	0	0	1	1
Serine/threonine-protein kinase 35	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
Rhodopsin kinase GRK7	0	0	1	1
Serine/threonine-protein kinase 32A	0	0	1	1
Myosin-IIIb	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	1	1
Cyclin-dependent kinase-like 2	0	0	1	1
Serine/threonine-protein kinase Sgk3	0	0	1	1
Atypical kinase COQ8B, mitochondrial	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Cyclin-dependent kinase 15	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
SRSF protein kinase 1	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	1	1
Serine/threonine-protein kinase RIO1	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO2	0	0	1	1
Cyclin-dependent kinase 19	0	0	1	1
Transient receptor potential cation channel subfamily M member 6	0	0	1	1
Testis-specific serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 33	0	0	1	1
Serine/threonine-protein kinase DCLK3	0	0	1	1
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	1	1
Homeodomain-interacting protein kinase 2	0	0	1	1
Tyrosine-protein kinase Srms	0	0	1	1
Homeodomain-interacting protein kinase 3	0	0	1	1
Serine/threonine-protein kinase PLK3	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	1	1
Serine/threonine-protein kinase Nek6	0	0	1	1
SNF-related serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase LATS2	0	0	1	1
Serine/threonine-protein kinase 36	0	0	1	1
Serine/threonine-protein kinase 32B	0	0	1	1
Serine/threonine-protein kinase PLK2	0	0	1	1
Serine/threonine-protein kinase MARK1	0	0	1	1
Serine/threonine-protein kinase pim-2	0	0	1	1
Serine/threonine-protein kinase PAK 5	0	0	1	1
eIF-2-alpha kinase GCN2	0	0	1	1
Phosphatidylinositol 4-kinase beta	0	0	1	1
Serine/threonine-protein kinase 17A	0	0	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	1	1
Ephrin type-A receptor 6	0	0	1	1
Death-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase tousled-like 1	0	0	1	1
ALK tyrosine kinase receptor	0	0	1	1
SRSF protein kinase 3	0	0	1	1
Cyclin-dependent kinase 11A	0	0	1	1
Aurora kinase C	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	1	1
Microtubule-associated serine/threonine-protein kinase 1	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Transporter	0	1	0	1
Glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Adenosylhomocysteinase	0	1	0	1
RNA-directed RNA polymerase	0	1	1	2
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	2	1	3
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
pyruvate kinase PKM isoform a	1	0	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	0	0	1
DNA polymerase beta	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine kinase	0	1	0	2
Solute carrier family 22 member 7	0	0	0	1
Butyrophilin subfamily 3 member A1	0	0	1	2
Neutrophil collagenase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
Matrix metalloproteinase-14	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	2	0	2
H	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Histiocytosis, Non-Langerhans-Cell

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (378)

Protein Targets (1,647)

Histiocytosis, Non-Langerhans-Cell

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (378)

Drugs Studied (149)

Protein Targets (1,647)