Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.
| Excerpt | Reference |
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| "Vascular calcification is prevalent in patients with chronic kidney disease and leads to increased cardiovascular morbidity and mortality." | ( Choi, YK; Ha, CM; Harris, RA; Jeong, D; Kim, H; Kim, HJ; Kim, HS; Kim, JM; Kim, JR; Kim, JY; Lee, IK; Lee, K; Lee, SJ, 2012) |
| "Vascular calcification is prevalent in patients with diabetes and chronic kidney disease." | ( Imaizumi, T; Iso, T; Kurabayashi, M; Shimizu, T; Suga, T; Takeuchi, M; Tanaka, T; Yamagishi, S, 2011) |
| "Vascular calcification is common in patients with chronic kidney disease (CKD) and contributes to the increased rate of cardiovascular morbidity and mortality." | ( Almaden, Y; Martinez-Moreno, JM; Muñoz-Castañeda, JR; Rodriguez, M; Rodríguez-Ortiz, ME, 2011) |
| "Vascular calcification is a major clinical problem and elucidating the underlying mechanism is important to improve the prognosis of patients with cardiovascular disease." | ( Alexander, MY; Canfield, AE; Heideman, DA; Jiagbogu, N; Liu, Y; Wang, T; Yan, J, 2011) |
| "Vascular calcification is associated with significant cardiovascular morbidity and mortality in patients with chronic kidney disease (CKD)." | ( Chonchol, M; Kendrick, J, 2011) |
| "Vascular calcification is an important problem in the patients with diabetes and chronic kidney disease (CKD) , and contributes to the increased risk of cardiovascular events by a variety of mechanisms, including an increase in arterial stiffness by medial calcification or an increase in plaque vulnerability by a specific type of atherosclerotic calcification." | ( Kurabayashi, M, 2011) |
| "Vascular calcification is a predictor of cardiovascular morbidity and mortality." | ( Cranenburg, EC; Floege, J; Heidenreich, S; Holzmann, S; Jahnen-Dechent, W; Ketteler, M; Krueger, T; Magdeleyns, EJ; Schlieper, G; Schurgers, LJ; Vermeer, C; Westenfeld, R, 2012) |
| "Vascular calcification is an active and complex process that involves numerous mechanisms responsible for calcium depositions in arterial walls." | ( Karwowski, W; Myśliwiec, M; Naumnik, B; Szczepański, M, 2012) |
| "Vascular calcification is a highly regulated process." | ( Akizawa, T; Aoshima, Y; Kinugasa, E; Koiwa, F; Kondo, F; Kumata, C; Mizobuchi, M; Nakazawa, A; Ogata, H; Ono, N, 2012) |
| "Vascular calcification is an active deposition process of calcium phosphate which resembles bone formation and is highly regulated by osteoblast-like cells." | ( An, Y; Chen, D; Jiang, Y; Liu, N; Ren, L; Wang, Z; Zhu, Y, 2012) |
| "Vascular calcification is frequent in dialysis patients and is associated with increased mortality." | ( Asci, G; Dheir, H; Duman, S; Kircelli, F; Ok, E; Ozkahya, M; Sevinc Ok, E; Sezis Demirci, M; Toz, H, 2012) |
| "Vascular calcification is a major risk factor of cardiovascular mortality, particularly for patients with end-stage renal disease and diabetes." | ( Dai, XY; Guan, Y; Kong, W; Wang, CY; Wang, X; Wilson, GM; Xu, MJ; Zhao, G; Zhao, MM, 2012) |
| "Vascular calcification is associated with increased cardiovascular mortality in chronic hemodialysis patients." | ( Caliskan, Y; Erten, G; Karahan, G; Ozel, A; Ozkok, A; Sakaci, T; Unsal, A; Yildiz, A, 2012) |
| "Vascular calcification is highly prevalent in certain patient populations, especially in those with chronic kidney disease (CKD), and it is plausible vitamin K may contribute to reducing vascular calcification in patients at higher risk." | ( Holden, RM; Shea, MK, 2012) |
| "Vascular calcification is one of the recently revealed side-effects of VKA." | ( Chatrou, ML; Hackeng, TM; Reutelingsperger, CP; Schurgers, LJ; Winckers, K, 2012) |
| "Vascular calcification is a pathological process common in patients with disorders of mineral metabolism and mediated by vascular smooth muscle cells (VSMCs)." | ( Kapustin, AN; Shanahan, CM, 2012) |
| "Vascular calcification is common in chronic kidney disease, where cardiovascular mortality remains the leading cause of death." | ( Giachelli, CM; Hu, MC; Kuro-o, M; Lau, WL; Leaf, EM; Moe, OW; Takeno, MM, 2012) |
| "Vascular calcification is one of the common complications in diabetes mellitus." | ( Gao, M; Liu, B; Liu, H; Tang, R; Wu, M; Zhang, X, 2012) |
| "Vascular calcification is a hallmark of advanced atherosclerosis." | ( Bednarczyk, A; Boucher, P; Boudier, C; Bruban, V; Chambon, P; Chollet, ME; Coudane, F; El Asmar, Z; Foppolo, S; Herz, J; Matz, RL; Metzger, D; Mlih, M; Ninio, E; Schaeffer, C; Terrand, J; Thiersé, D; Van Dorsselaer, A; Wahli, W; Woldt, E, 2012) |
| "Vascular calcification is an active and regulated process that is similar to bone formation." | ( Iso, T; Kawai-Kowase, K; Kurabayashi, M; Shimizu, T; Tanaka, T, 2012) |
| "Vascular calcification is a hallmark of cardiovascular disease." | ( Choi, HR; Kang, HA; Kang, HS; Lee, HY; Lee, KM; Oh, JW; Park, M; Yun, CH, 2012) |
| "Vascular calcification is associated with mortality and cardiovascular events in patients with chronic kidney disease." | ( Fujii, H; Goto, S; Kitamura, K; Kono, K; Nakai, K; Nishi, S, 2013) |
| "Medial vascular calcification is highly prevalent in chronic kidney disease (CKD), and it is a risk factor for mortality." | ( Adams, MA; Holden, RM; Pang, J; Shobeiri, N, 2013) |
| "Vascular calcification is highly associated with cardiovascular disease mortality, particularly in high-risk patients with diabetes and chronic kidney diseases (CKD)." | ( Giachelli, CM; Rementer, C; Wu, M, 2013) |
| "Atherosclerosis and vascular calcification are major contributors to cardiovascular morbidity and mortality among chronic kidney disease patients." | ( Benchitrit, J; Drüeke, TB; Edelman, A; Galmiche, A; Guerrera, IC; Guillonneau, F; Ivanovski, O; Joki, N; Lacour, B; Lucas, A; Maizel, J; Marçon, F; Massy, ZA; Nguyen-Khoa, T; Nikolov, IG; Phan, O, 2013) |
| "Vascular calcification is an actively regulated process driven by vascular smooth muscle cell (VSMC) adaptation and ultimately dysfunction, leading to the induction of active osteogenic processes within the vessel wall." | ( Shanahan, CM, 2013) |
| "Vascular calcification is a common pathobiological process which occurs among the elder population and in patients with diabetes and chronic kidney disease." | ( Fang, X; Guan, S; Li, W; Qiu, H; Xin, H; Zhou, S, 2013) |
| "Although vascular calcifications are frequently observed as incidental findings in HR-pQCT scans, they have not yet been incorporated into quantitative HR-pQCT analyses." | ( Berzaczy, G; Burghardt, AJ; Cejka, D; Diarra, D; Link, TM; Loewe, C; Patsch, JM; Samelson, EJ; Vilayphou, N; Weber, M; Zulliger, MA, 2014) |
| "Vascular calcification is an independent risk factor for cardiovascular disease." | ( Boor, P; Brandenburg, VM; Fekete, BC; Floege, J; Jahnen-Dechent, W; Kaesler, N; Ketteler, M; Krüger, T; Oelenberg, S; Schlieper, G; Schurgers, LJ; van de Sandt, AM; Vermeer, C; Veulemans, V; Westenfeld, R, 2013) |
| "Vascular calcification is a common comorbidity in elderly patients with diabetes mellitus or renal insufficiency." | ( Tang, ZY; Zhang, YT, 2014) |
| "Vascular calcification is a phenomenon of disturbed calcium deposition, as part of the calcium that is supposed to be deposited to our bones, is lodged to our vessels." | ( Pikilidou, MI; Scuteri, A; Yavropoulou, MP, 2014) |
| "Vascular calcification is highly prevalent in end-stage renal disease and independently predictive of future cardiovascular events and mortality." | ( Chonchol, M; Jablonski, KL, 2013) |
| "Vascular calcification is associated with significant cardiovascular morbidity and mortality, and has been demonstrated as an actively regulated process resembling bone formation." | ( Chen, Y; Liao, L; Lu, L; Song, Y; Wang, S; Wu, W; Ye, M; Yu, H; Zhou, Q, 2013) |
| "Vascular calcification is a prominent feature of many diseases, including atherosclerosis, and it has emerged as a powerful predictor of cardiovascular morbidity and mortality." | ( Huang, K; Li, X; Liu, H; Qin, F, 2014) |
| "Vascular calcification is common among patients undergoing dialysis and is associated with mortality." | ( Coresh, J; Crainiceanu, C; Jaar, BG; Kao, WH; Oberai, PC; Parekh, RS; Plantinga, LC; Powe, NR; Scialla, JJ; Shafi, T; Sozio, SM, 2014) |
| "Vascular calcification is highly prevalent in patients with chronic kidney disease (CKD) and contributes to increased risk of cardiovascular disease and mortality." | ( Cao, H; Dai, C; Fang, L; He, W; Jiang, L; Su, W; Wen, P; Xu, H; Yang, J; Ye, H; Zhou, Y, 2014) |
| "Medial vascular calcification is a specific complication in chronic kidney disease (CKD) patients although its pathogenesis is poorly understood." | ( Hamada, C; Seto, T; Tomino, Y, 2014) |
| "Vascular calcification is an actively regulated process that culminates in organized extracellular matrix mineral deposition by osteoblast-like cells." | ( Cao, X; Chen, A; Guo, F; Li, C; Pang, L; Shi, C; Wan, M; Wang, W, 2014) |
| "Vascular calcification is a major risk factor for cardiovascular diseases." | ( Huang, W; Liu, YS; Tan, P; Wang, S; Wang, Y; Wang, YJ; Zhan, JK, 2014) |
| "Vascular calcification is a serious cardiovascular complication that contributes to the increased morbidity and mortality of patients with diabetes mellitus." | ( Bradley, WE; Chatham, JC; Chen, Y; Dell'Italia, LJ; Heath, JM; Litovsky, S; Sun, Y; Wu, H; Yuan, K, 2014) |
| "Vascular calcification is highly correlated with increased cardiovascular morbidity and mortality." | ( Feng, H; Lei, H; Li, H; Li, L; Wang, C; Wang, JY; Wu, D; Wu, LL; Zhou, Y, 2014) |
| "Vascular calcification is highly correlated with cardiovascular disease morbidity and mortality." | ( Callegari, A; Coons, ML; Ricks, JL; Rosenfeld, ME; Scatena, M, 2014) |
| "Vascular calcification is an active process in which vascular smooth muscle cells (VSMCs) adopt an osteoblastic phenotype and deposit hydroxyapatite crystals; apoptosis of VSMCs also promotes this deposition." | ( DiNicolantonio, JJ; McCarty, MF, 2014) |
| "Vascular calcifications are a hallmark of advanced cardiovascular disease in patients with chronic kidney disease." | ( Freise, C; Querfeld, U, 2014) |
| "Vascular calcification is the leading cause of cardiovascular diseases in chronic kidney disease (CKD) patients." | ( Cai, Y; He, D; Liu, XF; Wang, X; Xu, MJ, 2014) |
| "Vascular calcification is a strong predictor of cardiovascular morbidity and mortality, especially in individuals with chronic kidney disease or diabetes." | ( Jeong, D; Kim, H; Lee, K, 2014) |
| "Vascular calcification is an active, highly regulated process that shares many similarities with normal bone formation." | ( Giachelli, CM; Paloian, NJ, 2014) |
| "Vascular calcification is frequently found already in early stages of chronic kidney disease (CKD) patients and is associated with high cardiovascular risk." | ( Alesutan, I; Lang, F; Ritz, E; Voelkl, J, 2014) |
| "Cardiovascular calcification is well known as an important factor for poor prognosis in CKD patients." | ( Hayashi, T; Joki, N, 2014) |
| "Vascular calcification is associated with increased risk of morbidity and mortality in patients with cardiovascular diseases, chronic kidney diseases, and diabetes." | ( Ahn, Y; Cho, JG; Cho, SN; Choi, SY; Hong, YJ; Jeong, MH; Kee, HJ; Kim, GR; Kim, IK; Park, HW; Park, JC; Ryu, Y, 2014) |
| "Vascular calcification is an unfavorable event in the natural history of atherosclerosis that predicts cardiovascular morbidity and mortality." | ( Blasetti Fantauzzi, C; Iacobini, C; Menini, S; Pugliese, G, 2015) |
| "Vascular calcification is a risk factor for causing cardiovascular events and has a high prevalence among chronic kidney disease (CKD) patients." | ( Fan, X; Feng, JM; Liu, LL; Ma, JF; Ren, C; Sun, L; Sun, W; Sun, YT; Wang, LN; Xu, TH; Yao, L, 2015) |
| "Cardiovascular calcification is both a risk factor and contributor to morbidity and mortality." | ( Brandenburg, V; Floege, J; Reutelingsperger, C; Schlieper, G; Schurgers, L, 2016) |
| "Vascular calcification is an independent risk factor for the development of cardiovascular disease and is classified into two types based on the site of calcification : intimal atherosclerotic calcification and Mönckeberg's medial calcification." | ( Shioi, A, 2015) |
| "Vascular calcification is known to be an important risk factor influencing mortality in CKD patients." | ( Fukagawa, M; Kakuta, T; Omata, M, 2015) |
| "Vascular calcification is commonly seen with aging, chronic kidney disese (CKD), diabetes, and atherosclerosis, and is closely associated with cardiovascular morbidity and mortality." | ( Kurabayashi, M, 2015) |
| "Vascular calcification is a risk factor for cerebral and cardiovascular events and has a high prevalence among elderly." | ( Akishita, M; Akiyoshi, T; Ogawa, S, 2015) |
| "Vascular calcification is the abnormality in chronic kidney disease-mineral bone disorder (CKD-MBD) that directly affects the prognosis in relation with cardiovascular diseases." | ( Hanafusa, N, 2015) |
| "Vascular calcification is prevailing in patients suffering from diabetes mellitus and/or chronic kidney disease, and carries a poor prognosis." | ( Kurozumi, A; Nakano, K; Okada, Y; Tanaka, Y, 2015) |
| "Vascular calcification is very common in patients with end-stage renal disease (ESRD) and has been found to be associated with mineral and bone disorders." | ( Nitta, K; Ogawa, T, 2015) |
| "Vascular calcification is a complex biological process that is a hallmark of atherosclerosis." | ( Bennett, MR; Bird, JL; Brindle, KM; Davenport, AP; Dweck, MR; Gallagher, FA; Irkle, A; Joshi, FR; Lewis, DY; Newby, DE; Rudd, JH; Skepper, JN; Vesey, AT; Warburton, EA, 2015) |
| "Vascular calcification is a frequent cause of morbidity and mortality in patients with CKD and the general population." | ( Cannata-Andía, JB; Carrillo-López, N; Fernández-Martín, JL; Martínez-Arias, L; Naves-Díaz, M; Panizo, S; Rodríguez, I; Ruiz-Torres, MP, 2016) |
| "Vascular calcification is a common complication associated with chronic kidney disease and the major cause of cardiovascular disease in patients with end-stage renal disease." | ( Liu, ZH, 2015) |
| "Vascular calcification is an independent risk factor for cardiovascular disease." | ( Hirata, K; Rikitake, Y; Satomi-Kobayashi, S; Terao, Y, 2015) |
| "Cardiovascular calcification is prevalent in the aging population and in patients with chronic kidney disease (CKD) and diabetes mellitus, giving rise to substantial morbidity and mortality." | ( Chatrou, ML; Horn, P; Kelm, M; Potthoff, SA; Scheiber, D; Schurgers, LJ; Veulemans, V; Westenfeld, R, 2015) |
| "Vascular calcification is known to reduce the elasticity of aorta." | ( Azechi, T; Sato, F; Sudo, R; Wachi, H, 2015) |
| "Vascular calcification is a frequent complication of atherosclerosis, diabetes and chronic kidney disease." | ( Agarwal, A; Arosio, P; Balla, G; Balla, J; Balogh, E; Bányai, E; Becs, Á; Becs, G; Eaton, JW; Jeney, V; Kovács, KÉ; Nyitrai, M; Poli, M; Zarjou, A, 2016) |
| "Vascular calcification is a characteristic feature of aging, atherosclerosis, diabetes mellitus, and end-stage renal disease." | ( Akishita, M; Akiyoshi, T; Iijima, K; Kahyo, T; Ogawa, S; Ota, H; Ouchi, Y; Setou, M; Son, BK, 2016) |
| "This increase in vascular calcification is due to inhibition of the enzyme matrix gamma-carboxyglutamate Gla protein (MGP)." | ( Goldhaber, SZ; Poterucha, TJ, 2016) |
| "Vascular calcification is an important risk factor associated with mortality among patients with chronic kidney disease." | ( Dai, W; Diao, Z; Guo, W; Han, X; Liu, S; Liu, W, 2016) |
| "Vascular calcification is a common feature of major cardiovascular diseases." | ( Aikawa, E; Aikawa, M; Goettsch, C; Hagita, S; Hutcheson, JD; Iwata, H; Kjolby, M; Kramann, R; Libby, P; Michel, T; Nykjaer, A; Pham, T; Rader, DJ; Rogers, M; Shibasaki, M; Singh, SA, 2016) |
| "Vascular calcification is prevalent in clinical states characterized by low-grade chronic inflammation, such as chronic kidney disease (CKD)." | ( Aghagolzadeh, P; Bachtler, M; Bijarnia, R; Jackson, C; Odermatt, A; Pasch, A; Radpour, R; Smith, ER, 2016) |
| "Medial vascular calcification is a common complication of chronic kidney disease (CKD)." | ( Agharazii, M; Cornfield, DN; Gobeil, S; Lamalice, L; Larivière, R; Mokas, S; Richard, DE, 2016) |
| "Vascular calcification is an active process of osteoblastic differentiation of vascular smooth muscle cells; however, its definite mechanism remains unknown." | ( Chen, XJ; Liang, QH; Ma, YY; Song, M; Sun, L; Wang, N; Wang, YZ; Yi, PF; Zhang, B, 2016) |
| "Vascular calcification is one of the major complications of cardiovascular disease and is an independent risk factor for myocardial infarction and cardiac death." | ( Akishita, M; Hashizume, T; Nanao-Hamai, M; Ogawa, S; Son, BK, 2016) |
| "Pathologic vascular calcification is a significant reason for mortality and morbidity in patients who suffer from end-stage renal disease (ESRD)." | ( Du, Y; Li, G; Li, Y; Wang, L; Zhang, P; Zhou, F, 2016) |
| "Vascular calcification is a strong independent predictor of increased cardiovascular morbidity and mortality and has a high prevalence among patients with chronic kidney disease." | ( Chang, X; Cong, G; Cui, L; Hao, L; Li, Z, 2017) |
| "Vascular calcification is a characteristic feature of atherosclerosis and is considered as an independent predictor of cardiovascular risk." | ( Bangash, AB; Chen, Y; Shao, C; Song, J; Wang, C; Wang, Z; Yan, J; Zhong, W, 2017) |
| "Vascular calcification is initiated by exosomes, and proteomic analysis revealed that VSMC exosomes are loaded with Gla-containing coagulation factors: IX and X, PT (prothrombin), and proteins C and S." | ( Hackeng, TM; Harrison, P; Heiss, A; Jahnen-Dechent, W; Kapustin, AN; McNair, R; Reynolds, JL; Schlieper, G; Schoppet, M; Schurgers, LJ; Shanahan, CM, 2017) |
| "Vascular calcification is a risk predictor and common pathological change in cardiovascular diseases that are associated with elastin degradation and phenotypic transformation of vascular smooth muscle cells via gelatinase matrix metalloproteinase-2 (MMP2)." | ( Han, C; Jiang, W; Lin, Q; Qin, X; Yang, H; Zhang, Z, 2017) |
| "Vascular calcification is commonly seen in elderly people, though it can also appear in middle-aged subjects affected by premature vascular aging." | ( Alique, M; Bodega, G; Bohórquez, L; Carmona, A; Carracedo, J; Luna, C; Luque, R; Noci, MV; Ramírez, R; Ruíz-Torres, MP; Troyano, N, 2017) |
| "Cardiovascular calcification is one of the most severe outcomes associated with cardiovascular disease and often results in significant morbidity and mortality." | ( Cao, R; Chen, L; Liu, C; Liu, J; Shen, Y; Tang, Z; Wu, Y; Xiao, X; Xu, C; Zhang, Q; Zhao, H; Zhao, Q; Zheng, Y; Zhong, J; Zu, X, 2017) |
| "Vascular calcification is a common feature in atherosclerosis and associates with cardiovascular events." | ( Beloqui, O; Cortés, A; Díez, J; Fortuño, A; Landecho, MF; Moreno, MU; Pejenaute, Á; San José, G; Zalba, G, 2017) |
| "Vascular calcification is associated with increased risk of myocardial infarction and stroke." | ( Handelsman, DJ; Heather, AK; Hughes, G; Liong, EC; McGrath, KCY; McRobb, LS; Tan, JTM; Tsatralis, T, 2017) |
| "Vascular calcification is driven by aldosterone-sensitive osteogenic transformation of vascular smooth muscle cells (VSMCs)." | ( Alesutan, I; Borst, O; Castor, T; Feger, M; Gawaz, M; Kratschmar, DV; Kuro-O, M; Lang, F; Leibrock, C; Mia, S; Odermatt, A; Pieske, B; Pilz, S; Sacherer, M; Tomaschitz, A; Viereck, R; Voelkl, J; Wagner, CA, 2017) |
| "Vascular calcification is actively regulated by inductive and inhibitory mechanisms (including vascular smooth muscle cell adaptation) and results from an active osteogenic process." | ( Ait-Mohand, K; Ausseil, J; Boullier, A; Cornu, M; Courtois, J; Da Nascimento, S; Darwiche, W; Elboutachfaiti, R; Gomila, C; Hodroge, A; Kamel, S; Kovensky, J; Lorne, E; Mansour, A; Massy, ZA; Petit, E; Rossi, C; Schembri, C; Sonnet, P; Toumieux, S; Trécherel, E; Verissimo, T, 2017) |
| "Vascular calcification is established to be a critical factor in diabetes mellitus, which causes cardiovascular and amputation complication of diabetic patients." | ( Bao, Z; Li, L; Sun, Z; Wang, Z; Xu, L; Xu, S; Yan, J; Ye, F; Zhu, J, 2017) |
| "Vascular calcifications are associated with nephrolithiasis." | ( Calle, J; Monga, M; Patel, ND; Remer, EM; Ward, RD, 2017) |
| "Vascular calcification is a different process, stringently regulated mainly by local factors, in which osteoblast-like cells accumulate in the muscular layer of arteries ultimately taking on the physiological appearance of bone." | ( Siltari, A; Vapaatalo, H, 2018) |
| "Vascular calcification is prevalent and associated with adverse outcome without available therapy." | ( Cao, F; Cao, X; Fu, K; Liu, J; Liu, X; Shen, F; Wang, S; Zhao, Y, 2017) |
| "Vascular calcification is common among patients with chronic kidney disease (CKD), and it is associated with all-cause and cardiovascular disease mortality." | ( Block, G; Chonchol, M; Isakova, T; Jovanovich, A; Miyazaki, M; Smits, G; Stubbs, J, 2018) |
| "Vascular calcification is a frequent complication in chronic haemodialysis patients and is associated with adverse outcomes." | ( Azpiazu, D; Egido, J; González-Parra, E; Ortiz, A; Villa-Bellosta, R, 2017) |
| "Vascular calcification is a common health problem related to oxidative stress, inflammation, and circulating calciprotein particles (CPP)." | ( Aghagolzadeh, P; Bachtler, M; Feelisch, M; Lister, A; Odermatt, A; Pasch, A; Radpour, R; Smith, ER; van Goor, H, 2017) |
| "Vascular calcification is a tightly regulated process that increases during ageing and occurs mainly in patients with diabetes and chronic renal failure." | ( Liberman, M; Marti, LC, 2017) |
| "Vascular calcification is common and may affect cardiac function in patients with end-stage renal disease (ESRD)." | ( Cho, A; Choi, MJ; Jeon, HJ; Kim, EJ; Lee, YK; Noh, JW; Oh, J; Rhee, SY; Ryu, J; Shin, DH; Yoon, JW, 2017) |
| "Vascular calcification is a risk factor that predicts adverse cardiovascular complications of several diseases including atherosclerosis." | ( Agarwal, A; Bradley, WE; Byon, CH; Chen, Y; Dell'Italia, LJ; Sanders, PW; Sun, Y; Wu, H; Yang, Y, 2017) |
| "Vascular calcification is a major cause of morbidity and mortality." | ( Borland, SC; Borland, SJ; Canfield, AE; Francis, SE; Merry, CLR; Morgan, MR; Morris, TG, 2017) |
| "Vascular calcification is one of the most important factors for high morbidity and mortality from cardiovascular and cerebrovascular diseases." | ( Dai, SL; Shang, YQ; Wang, XC; Wu, W; Yi, F, 2017) |
| "Vascular calcification is a serious complication of chronic kidney disease, but the current therapeutic strategy is insufficient for preventing its progression." | ( Fukagawa, M; Hamano, N; Komaba, H, 2017) |
| "Vascular calcification is the deposition of mineral in the artery wall by vascular smooth muscle cells (VSMCs) in response to pathological stimuli." | ( Borland, SJ; Canfield, AE; Clarke, CJ; Hannun, YA; Morris, TG; Ohanian, J; Ohanian, V; Wilson, C, 2018) |
| "Vascular calcification is related to vascular diseases, for example, atherosclerosis, and its comorbidities, such as diabetes and chronic kidney disease." | ( Faggioli, G; Pasquinelli, G; Zazzeroni, L, 2018) |
| "Vascular calcification is highly prevalent in end-stage renal disease (ESRD) and is a significant risk factor for future cardiovascular events and death." | ( Chang, WJ; Chen, YY; Li, SY; Tsai, MT, 2018) |
| "Vascular calcification is an important risk factor for cardiovascular disease, and is closely associated with all-cause mortality." | ( Barinda, AJ; Emoto, N; Hirata, KI; Ikeda, K, 2017) |
| "Vascular calcification is a pathologic response to mineral imbalances and is prevalent in atherosclerosis, diabetes mellitus, and chronic kidney disease." | ( Cai, Y; Flores, AM; Guzman, RJ; Lin, T; Wang, XL, 2018) |
| "Vascular calcification is prevalent in patients with atherosclerosis, and oxidative stress promotes pathogenesis of atherosclerosis." | ( Bradley, WE; Chen, J; Chen, Y; Dell'Italia, LJ; Sun, Y; Wu, H; Yang, Y, 2018) |
| "Pathologic cardiovascular calcification is associated with a number of conditions and is a common complication of chronic kidney disease." | ( O'Neill, WC; Villa-Bellosta, R, 2018) |
| "While vascular calcification is an important factor regulating prognosis in dialysis patients, its components have not been adequately studied." | ( Higuchi, C; Nakaoka, T; Nishizawa, Y; Nitta, K; Ogawa, T; Omori, H; Sakura, H, 2018) |
| "Vascular calcification is associated with increased cardiovascular morbidity and mortality in patients with atherosclerosis, diabetes and chronic kidney disease." | ( Ashton, N; Borland, SJ; Canfield, AE; Eyre, HJ; Gilmore, A; Hyde, GD; Inkson, CA; Kalra, PA; Pond, E; Ponnusamy, A; Sinha, S; Taylor, RF, 2018) |
| "Vascular calcification is a main cause of increased cardiovascular morbidity and mortality in chronic kidney disease (CKD) patients." | ( Gan, L; Li, L; Lin, J; Liu, Q; Ou, S; Wei, X; Wu, W, 2018) |
| "Vascular calcification is extremely common and associated with major adverse cardiovascular events." | ( Cao, F; Liu, J; Liu, S; Liu, X; Mi, Y, 2018) |
| "Vascular calcification is common in patients with end-stage renal disease (ESRD)." | ( Nitta, K; Ogawa, T, 2018) |
| "Uremic vascular calcification is a regulated cell-mediated process wherein cells in the arterial wall transdifferentiate to actively calcifying cells resulting in a process resembling bone formation." | ( Gravesen, E; Høgdall, E; Kjær, A; Lewin, E; Mace, M; Morevati, M; Nielsen, C; Nordholm, A; Olgaard, K, 2018) |
| "Cardiovascular calcification is still a major burden for patients with chronic kidney disease (CKD)." | ( Schlieper, G, 2018) |
| "Vascular calcification is widespread and clinically significant, contributing to substantial morbidity and mortality." | ( Chen, R; Li, B; Shao, C; Wang, CP; Wang, ZQ; Xu, Y; Yan, JC; Yang, P; Zhong, W, 2018) |
| "Vascular calcification is a pathologic phenomenon consisting of calcium phosphate crystal deposition in the vascular walls." | ( Azpiazu, D; Gonzalo, S; Villa-Bellosta, R, 2019) |
| "Vascular calcification is common in chronic kidney disease (CKD) patients, while erythropoietin (EPO) is widely used in the treatment of renal anemia in CKD patients, whether there is a link between the two is still not clear." | ( Gan, H; He, J; Zhao, L; Zhong, X, 2019) |
| "Vascular calcification is a common finding in atherosclerosis and in patients with chronic kidney disease." | ( Bai, HY; Higaki, A; Higaki, J; Horiuchi, M; Iwanami, J; Kan-No, H; Kukida, M; Min, LJ; Mogi, M; Okura, T; Shan, BS; Tsukuda, K; Yamauchi, T, 2019) |
| "Vascular calcification is a critical complication in patients with chronic kidney disease (CKD) because it is predictive of cardiovascular events and mortality." | ( Chen, R; Chen, RM; Hou, YC; Lin, YF; Liu, WC; Lu, CL; Lu, KC; Yen, TH; Zheng, CM, 2019) |
| "Vascular calcification is a common complication in patients with chronic kidney disease (CKD)." | ( Bao, S; Diao, Z; Guo, W; Guo, Y; Han, X; Liu, W; Wang, L, 2019) |
| "Vascular calcification is highly prevalent in end-stage renal diseases and is predictive of cardiovascular events and mortality." | ( An, J; Huang, K; Li, Y; Liang, M; Tong, Q; Wang, C; Xu, W; Zhang, F, 2019) |
| "Vascular calcification is characterized by the accumulation of hydroxyapatite crystals, which is a result of aberrant mineral metabolism." | ( Choe, N; Jeong, G; Kim, J; Kim, YK; Kook, H; Kwon, DH; Lim, YH; Park, WJ; Ryu, J; Shin, S, 2019) |
| "Vascular calcification is a major contributor to increased cardiovascular mortality in chronic kidney disease (CKD)." | ( de Baaij, JHF; Zeper, LW, 2019) |
| "Objective- Vascular calcification is associated with high risk of cardiovascular events and mortality." | ( Balogh, E; Jeney, V; Méhes, G; Paragh, G; Tóth, A; Trencsényi, G, 2019) |
| "Vascular calcification is a complication of diseases and conditions such as chronic kidney disease, diabetes, and aging." | ( Enaka, M; Muragaki, Y; Wei, R, 2019) |
| "Cardiovascular calcification is associated with cardiovascular morbidity and mortality of patients with end-stage renal diseases (ESRD)." | ( Guo, L; Han, L; Lv, L; Wang, D; Wang, J; Xu, D; Xu, Y; Yin, Z; Zeng, F; Zhou, H, 2019) |
| "Vascular calcification is a recognised source of morbidity among mid-age and elderly subjects." | ( Cochran, M, 2019) |
| "Vascular calcification is a common problem in the elderly with diabetes, heart failure and end-stage renal disease." | ( Guo, B; Jia, Y; Lu, Y; Ma, Y; Sun, J; Wang, R; Wei, R, 2019) |
| "Vascular calcification is an independent predictor of cardiovascular disease, and therefore, inhibition or regression of this processes is of clinical importance." | ( de Leeuw, PW; Kroon, AA; Schurgers, LJ; Vossen, LM, 2019) |
| "Vascular calcification is highly prevalent in patients with chronic kidney disease." | ( Chen, M; Chen, Y; Li, Y; Li, Z; Liu, H; Liu, X; Lu, L; Ou, C; Yan, J; Yang, P; Zhang, X; Zhong, X, 2020) |
| "Vascular calcification is a life-threatening complication in patients with chronic kidney disease." | ( Fukagawa, M; Komaba, H; Nakagawa, Y, 2020) |
| "Vascular calcification is intimately associated with CV events and mortality and is a chronic inflammatory process in which activated macrophages promote osteoblastic differentiation of vascular smooth muscle cells (VSMCs) through the production of proinflammatory cytokines such as IL-1β, IL-6, TNF-α, and oncostatin M (OSM) in both intimal and medial layers of arterial walls." | ( Emoto, M; Morioka, T; Shioi, A; Shoji, T, 2020) |
| "Vascular calcification is commonly observed in atherosclerosis and diabetes." | ( Hu, Z; Li, M; Li, S; Shao, J; Wang, Z; Xia, H; Yu, L, 2020) |
| "Vascular calcification is the pathological deposition of calcium/phosphate in the vascular system and is closely associated with cardiovascular morbidity and mortality." | ( Bae, MK; Bae, SK; Hwang, JJ; Kim, HJ; Kim, MK; Kim, Y; Park, HJ, 2020) |
| "Vascular calcification is a severe pathological event in the manifestation of atherosclerosis." | ( Babel, N; Claeys, L; Geißler, S; Pustlauk, W; Roch, T; Westhoff, TH, 2020) |
| "Vascular calcification is a commonly occurring pathological process and is recognized as an independent prognostic marker for cardiovascular morbidity and mortality." | ( Hansen, KC; Hill, RC; Johnson, SL; Lee, HS; Syedain, ZH; Thrivikraman, G; Tranquillo, RT, 2020) |
| "Vascular calcification is a recognized predictor of cardiovascular risk in the diabetic patient, with DNA damage and accelerated senescence linked to oxidative stress-associated pathological calcification." | ( Alexander, MY; Bartoli-Leonard, F; Schiro, A; Serracino Inglott, F; Weston, R; Wilkinson, FL, 2021) |
| "Vascular calcification is a highly regulated process similar to osteogenesis involving phenotypic change of vascular smooth muscle cells (VSMCs)." | ( Chen, A; Chen, Y; Dong, Q; Fu, M; Li, Y; Liu, W; Liu, X; Lu, L; Ou, JS; Wang, S; Yan, J; Yang, X, 2020) |
| "Vascular calcification is a common complication in patients with chronic kidney disease and associated with increased morbidity and mortality." | ( Kuo, WH; Lee, CT; Lee, YT; Leung, FF; Ng, HY; Tain, YL, 2020) |
| "Vascular calcification is a known complication of chronic kidney disease (CKD)." | ( Grewal, R; Le, TH; Levy, DS, 2020) |
| "Vascular calcification is an important risk factor for the mortality and morbidity in chronic kidney disease (CKD)." | ( Chen, J; Kong, X; Lu, Y; Shen, Y; Sheng, Y; Su, Z; Sun, W; Yang, C; Yang, S; Zong, P, 2020) |
| "Vascular calcification is common among aging populations and mediated by vascular smooth muscle cells (VSMCs)." | ( Ahmad, S; Bordoloi, J; Furmanik, M; Kapustin, A; Schurgers, LJ; Shanahan, CM; van Gorp, R; Whitehead, M, 2021) |
| "Vascular calcification is the pathological precipitation of phosphate and calcium in the vasculature and is closely associated with increased cardiovascular risk and mortality." | ( Bae, MK; Bae, SK; Kim, HJ; Kim, MK; Kim, Y; Park, HJ; Park, HR, 2020) |
| "Vascular calcification is a prognostic marker for cardiovascular mortality in chronic kidney disease (CKD) patients." | ( de Baaij, JHF; Hoenderop, JGJ; Ter Braake, AD; Vervloet, MG, 2022) |
| "Vascular calcification is an independent risk factor for cardiovascular diseases and all-cause mortality in end stage renal disease, and particularly in hemodialysis patients." | ( Alshahawey, M; El Borolossy, R; El Wakeel, L; Elsaid, T; Sabri, NA, 2021) |
| "Vascular calcification is a severe complication that increases the all-cause mortality of cardiovascular disease but lacks medical therapy." | ( Boström, KI; Cai, X; Ma, JA; Qiao, X; Wu, X; Yao, J; Yao, Y; Zhang, D; Zhang, L, 2021) |
| "Vascular calcification is a common and important cardiovascular risk factor in patients with chronic kidney disease (CKD)." | ( Lees, JS; Mark, PB; Witham, MD, 2021) |
| "Vascular calcification is a common pathologic condition in patients with chronic kidney disease (CKD) and aging individuals." | ( Chen, A; Chen, Y; Dong, Q; Fu, M; Lan, Z; Li, Y; Liang, Q; Liu, X; Lu, L; Ou, JS; Wang, S; Yan, J; Yang, P; Yang, X; Ye, Y, 2021) |
| "Vascular calcification is common in chronic kidney disease; however, the extent to which such condition can affect the renal microvasculature and the neighboring cell types is unclear." | ( Awuah Boadi, E; Bandyopadhyay, BC; Shin, S, 2021) |
| "Vascular calcification is very commonly observed in patients with chronic kidney disease (CKD), but there is no efficient therapy available." | ( Chen, A; Dong, Q; Fu, M; Lan, Z; Li, Y; Liang, Q; Liu, X; Lu, L; Ou, JS; Wang, S; Yan, J; Yang, X; Ye, Y, 2021) |
| "Vascular calcification is a major risk factor for cardiovascular disease and accounts for a large proportion of deaths from cardiovascular disease in patients with chronic kidney disease." | ( Tang, N; Zhang, Y; Zhou, J, 2021) |
| "Vascular calcification is an active process that increases cardiovascular disease (CVD) risk." | ( Akbulut, AC; Biessen, EAL; Brandenburg, V; Dzhanaev, R; Floege, J; Jahnen-Dechent, W; Jaminon, AMG; Kramann, R; Mees, B; Rapp, N; Reutelingsperger, CP; Schurgers, LJ; Temmerman, L; Uitto, J, 2021) |
| "Cardiovascular calcification is the ectopic deposition of calcium-phosphate crystals within the arterial wall and the aortic valve leaflets." | ( Cinetto, F; Donato, M; Faggin, E; Felice, C; Ferri, N; Lupo, MG; Rattazzi, M, 2021) |
| "Vascular calcification is highly prevalent in chronic kidney disease (CKD), and is characterized by transdifferentiation from contractile vascular smooth muscle cells (VSMCs) into an osteogenic phenotype." | ( Chen, M; Feng, L; Li, Z; Ou, C; Que, D; Wei, J; Yan, J; Yang, P; Zhang, X; Zhong, X, 2021) |
| "Vascular calcification is the heterotopic accumulation of calcium phosphate salts in the vascular tissue and is highly correlated with increased cardiovascular morbidity and mortality." | ( Bae, MK; Bae, SK; Kim, HJ; Kim, MK; Kim, Y; Park, HJ, 2021) |
| "Vascular calcification is common in chronic kidney disease (CKD) and associated with increased cardiovascular mortality." | ( Alesutan, I; Auer, T; Buehling, SS; Degenhart, G; Feger, M; Grebe, S; Hammer, F; Hauser, T; Krane, V; Lang, F; Malzahn, U; Masyout, J; Pasch, A; Tuffaha, R; Voelkl, J; Wanner, C, 2021) |
| "Vascular calcification is one of the most prevalent disorders in pediatric hemodialysis patients that eventually lead to cardiovascular morbidity." | ( El Borolossy, R; El-Farsy, MS, 2022) |
| "Development of vascular calcification is accelerated in patients with end-stage renal disease." | ( Aaltonen, L; Koivuviita, N; Kröger, H; Löyttyniemi, E; Metsärinne, K; Seppänen, M; Tong, X, 2022) |
| "Vascular calcification is a major manifestation of cardiovascular disease in advanced chronic kidney disease and is inhibited by vitamin K-dependent proteins." | ( Lees, JS; Mark, PB, 2022) |
| "Vascular calcification is a key process involved in cardiovascular morbidity and mortality in patients with chronic kidney disease (CKD)." | ( Bos, C; Hoekstra, T; Hoenderop, JGJ; Leenders, NHJ; Schurgers, LJ; Vervloet, MG, 2022) |
| "Vascular calcification is one of the most common complications of chronic kidney disease (CKD), which is closely associated with increased mortality and morbidity rates of CKD patients." | ( Chen, X; Duan, S; Guo, W; Liu, W; Liu, Y, 2022) |
| "Vascular calcification is associated with cardiovascular morbidity and mortality in people with CKD." | ( Ruderman, I; Smith, ER; Tiong, MK; Toussaint, ND; Xu, C, 2022) |
| "Vascular calcification is an important contributor to morbidity and mortality in many pathologies, including chronic kidney disease, diabetes mellitus, and atherosclerosis." | ( Akbulut, AC; Dzhanaev, R; Jahnen-Dechent, W; Jaminon, AMG; Rapp, N; Reutelingsperger, CP; Schurgers, LJ, 2022) |
| "Vascular calcification is commonly observed in chronic kidney disease (CKD) and is associated with increased morbidity and mortality." | ( Kuo, WH; Lee, CT; Lee, WC; Tain, YL; Wang, Y, 2022) |
| "Vascular calcification is a risk factor for cardiovascular and kidney diseases." | ( Argilés, À; Cortijo, I; Duranton, F; Gayrard, N; Jover, B; Laget, J; Muyor, K, 2022) |
| "Vascular calcification is an actively regulated process resembling bone formation and contributes to the cardiovascular morbidity and mortality of chronic kidney disease (CKD)." | ( Chen, A; Dong, Q; Fu, M; Lan, Z; Li, L; Li, Y; Liang, Q; Liu, X; Lu, L; Ou, JS; Qiu, X; Wang, S; Yan, J; Ye, Y; Zhu, Z, 2022) |
| "Vascular calcification is a process similar to bone formation, which is highly adjustable and active." | ( Chu, H; Li, Y; Mu, Y; Pan, Y; Sun, J; Wang, L; Wang, X, 2022) |
| "Vascular calcification is a known risk factor for cardiovascular events and mortality in patients with chronic kidney disease (CKD)." | ( Bjergfelt, SS; Bro, S; Christoffersen, C; Feldt-Rasmussen, B; Hjortkjær, HØ; Kofoed, KF; Lange, T; Sørensen, IMH, 2023) |
| "Vascular calcification is associated with aging, type 2 diabetes, and atherosclerosis, and increases the risk of cardiovascular morbidity and mortality." | ( Caporali, A; Corcoran, BM; Forsythe, RO; Jones, RA; Koo, E; MacRae, VE; Phadwal, K; Tang, K; Tang, Q, 2022) |
| "Vascular calcification is commonly observed in chronic kidney disease." | ( Chang, K; Chen, S; Jiang, L; Li, J; Li, Y; Liao, R; Qin, Z; Su, B; Yang, Q; Zhang, Z, 2022) |
| "Vascular calcification is an important risk factor for cardiovascular events, accompanied by DNA damage during the process." | ( Chen, A; Dong, Q; Fu, M; Lan, Z; Li, L; Li, Y; Liang, Q; Liu, X; Lu, L; Ou, JS; Wang, S; Yan, J; Ye, Y, 2022) |
| "Vascular calcification is a common pathological change of cardiovascular tissues in patients with chronic kidney disease, diabetes, hypertension and atherosclerosis." | ( Chen, JX; Chen, JY; Li, DY; Tan, X; Wang, SY; Wang, YH; Xie, YC; Zhong, H; Zhu, DX, 2022) |
| "Although vascular calcification is a recognised complication for haemodialysis patients, peritoneal dialysis (PD) patients are also at risk." | ( Davenport, A, 2023) |
| "The prevention of vascular calcification is important to improve the prognosis of such patients." | ( Araki, SI; Ishida, K; Kawakami, K; Kobashi, S; Nakashima, Y; Ohya, M; Shigematsu, T; Sonou, T; Tanaka, Y; Yamamoto, S; Yano, T; Yashiro, M, 2023) |
| "Vascular calcification is recognized as the advanced stage of atherosclerosis burden." | ( Gaj, S; Kovi, S; Man, S; Nakamura, K; Shimoyama, T; Uchino, K, 2023) |
| "Vascular calcification is accelerated in patients with diabetes mellitus and increases risk of cardiovascular events and mortality." | ( Chen, Y; Sun, Y; Yang, Y; Zhang, W, 2023) |
| "The pathogenesis of vascular calcification is incompletely understood, and until now, there have been no effective therapeutics for vascular calcification." | ( Li, P; Liu, R; Liu, Y; Shen, J; Sun, X; Wai Wong, VK; Wang, Q; Zhang, C; Zhao, M, 2023) |