"Vascular calcification is prevalent in patients with chronic kidney disease and leads to increased cardiovascular morbidity and mortality." | ( Choi, YK; Ha, CM; Harris, RA; Jeong, D; Kim, H; Kim, HJ; Kim, HS; Kim, JM; Kim, JR; Kim, JY; Lee, IK; Lee, K; Lee, SJ, 2012) |
"Vascular calcification is prevalent in patients with diabetes and chronic kidney disease." | ( Imaizumi, T; Iso, T; Kurabayashi, M; Shimizu, T; Suga, T; Takeuchi, M; Tanaka, T; Yamagishi, S, 2011) |
"Vascular calcification is common in patients with chronic kidney disease (CKD) and contributes to the increased rate of cardiovascular morbidity and mortality." | ( Almaden, Y; Martinez-Moreno, JM; Muñoz-Castañeda, JR; Rodriguez, M; Rodríguez-Ortiz, ME, 2011) |
"Vascular calcification is a major clinical problem and elucidating the underlying mechanism is important to improve the prognosis of patients with cardiovascular disease." | ( Alexander, MY; Canfield, AE; Heideman, DA; Jiagbogu, N; Liu, Y; Wang, T; Yan, J, 2011) |
"Vascular calcification is associated with significant cardiovascular morbidity and mortality in patients with chronic kidney disease (CKD)." | ( Chonchol, M; Kendrick, J, 2011) |
"Vascular calcification is an important problem in the patients with diabetes and chronic kidney disease (CKD) , and contributes to the increased risk of cardiovascular events by a variety of mechanisms, including an increase in arterial stiffness by medial calcification or an increase in plaque vulnerability by a specific type of atherosclerotic calcification." | ( Kurabayashi, M, 2011) |
"Vascular calcification is a predictor of cardiovascular morbidity and mortality." | ( Cranenburg, EC; Floege, J; Heidenreich, S; Holzmann, S; Jahnen-Dechent, W; Ketteler, M; Krueger, T; Magdeleyns, EJ; Schlieper, G; Schurgers, LJ; Vermeer, C; Westenfeld, R, 2012) |
"Vascular calcification is an active and complex process that involves numerous mechanisms responsible for calcium depositions in arterial walls." | ( Karwowski, W; Myśliwiec, M; Naumnik, B; Szczepański, M, 2012) |
"Vascular calcification is a highly regulated process." | ( Akizawa, T; Aoshima, Y; Kinugasa, E; Koiwa, F; Kondo, F; Kumata, C; Mizobuchi, M; Nakazawa, A; Ogata, H; Ono, N, 2012) |
"Vascular calcification is an active deposition process of calcium phosphate which resembles bone formation and is highly regulated by osteoblast-like cells." | ( An, Y; Chen, D; Jiang, Y; Liu, N; Ren, L; Wang, Z; Zhu, Y, 2012) |
"Vascular calcification is frequent in dialysis patients and is associated with increased mortality." | ( Asci, G; Dheir, H; Duman, S; Kircelli, F; Ok, E; Ozkahya, M; Sevinc Ok, E; Sezis Demirci, M; Toz, H, 2012) |
"Vascular calcification is a major risk factor of cardiovascular mortality, particularly for patients with end-stage renal disease and diabetes." | ( Dai, XY; Guan, Y; Kong, W; Wang, CY; Wang, X; Wilson, GM; Xu, MJ; Zhao, G; Zhao, MM, 2012) |
"Vascular calcification is associated with increased cardiovascular mortality in chronic hemodialysis patients." | ( Caliskan, Y; Erten, G; Karahan, G; Ozel, A; Ozkok, A; Sakaci, T; Unsal, A; Yildiz, A, 2012) |
"Vascular calcification is highly prevalent in certain patient populations, especially in those with chronic kidney disease (CKD), and it is plausible vitamin K may contribute to reducing vascular calcification in patients at higher risk." | ( Holden, RM; Shea, MK, 2012) |
"Vascular calcification is one of the recently revealed side-effects of VKA." | ( Chatrou, ML; Hackeng, TM; Reutelingsperger, CP; Schurgers, LJ; Winckers, K, 2012) |
"Vascular calcification is a pathological process common in patients with disorders of mineral metabolism and mediated by vascular smooth muscle cells (VSMCs)." | ( Kapustin, AN; Shanahan, CM, 2012) |
"Vascular calcification is common in chronic kidney disease, where cardiovascular mortality remains the leading cause of death." | ( Giachelli, CM; Hu, MC; Kuro-o, M; Lau, WL; Leaf, EM; Moe, OW; Takeno, MM, 2012) |
"Vascular calcification is one of the common complications in diabetes mellitus." | ( Gao, M; Liu, B; Liu, H; Tang, R; Wu, M; Zhang, X, 2012) |
"Vascular calcification is a hallmark of advanced atherosclerosis." | ( Bednarczyk, A; Boucher, P; Boudier, C; Bruban, V; Chambon, P; Chollet, ME; Coudane, F; El Asmar, Z; Foppolo, S; Herz, J; Matz, RL; Metzger, D; Mlih, M; Ninio, E; Schaeffer, C; Terrand, J; Thiersé, D; Van Dorsselaer, A; Wahli, W; Woldt, E, 2012) |
"Vascular calcification is an active and regulated process that is similar to bone formation." | ( Iso, T; Kawai-Kowase, K; Kurabayashi, M; Shimizu, T; Tanaka, T, 2012) |
"Vascular calcification is a hallmark of cardiovascular disease." | ( Choi, HR; Kang, HA; Kang, HS; Lee, HY; Lee, KM; Oh, JW; Park, M; Yun, CH, 2012) |
"Vascular calcification is associated with mortality and cardiovascular events in patients with chronic kidney disease." | ( Fujii, H; Goto, S; Kitamura, K; Kono, K; Nakai, K; Nishi, S, 2013) |
"Medial vascular calcification is highly prevalent in chronic kidney disease (CKD), and it is a risk factor for mortality." | ( Adams, MA; Holden, RM; Pang, J; Shobeiri, N, 2013) |
"Vascular calcification is highly associated with cardiovascular disease mortality, particularly in high-risk patients with diabetes and chronic kidney diseases (CKD)." | ( Giachelli, CM; Rementer, C; Wu, M, 2013) |
"Atherosclerosis and vascular calcification are major contributors to cardiovascular morbidity and mortality among chronic kidney disease patients." | ( Benchitrit, J; Drüeke, TB; Edelman, A; Galmiche, A; Guerrera, IC; Guillonneau, F; Ivanovski, O; Joki, N; Lacour, B; Lucas, A; Maizel, J; Marçon, F; Massy, ZA; Nguyen-Khoa, T; Nikolov, IG; Phan, O, 2013) |
"Vascular calcification is an actively regulated process driven by vascular smooth muscle cell (VSMC) adaptation and ultimately dysfunction, leading to the induction of active osteogenic processes within the vessel wall." | ( Shanahan, CM, 2013) |
"Vascular calcification is a common pathobiological process which occurs among the elder population and in patients with diabetes and chronic kidney disease." | ( Fang, X; Guan, S; Li, W; Qiu, H; Xin, H; Zhou, S, 2013) |
"Although vascular calcifications are frequently observed as incidental findings in HR-pQCT scans, they have not yet been incorporated into quantitative HR-pQCT analyses." | ( Berzaczy, G; Burghardt, AJ; Cejka, D; Diarra, D; Link, TM; Loewe, C; Patsch, JM; Samelson, EJ; Vilayphou, N; Weber, M; Zulliger, MA, 2014) |
"Vascular calcification is an independent risk factor for cardiovascular disease." | ( Boor, P; Brandenburg, VM; Fekete, BC; Floege, J; Jahnen-Dechent, W; Kaesler, N; Ketteler, M; Krüger, T; Oelenberg, S; Schlieper, G; Schurgers, LJ; van de Sandt, AM; Vermeer, C; Veulemans, V; Westenfeld, R, 2013) |
"Vascular calcification is a common comorbidity in elderly patients with diabetes mellitus or renal insufficiency." | ( Tang, ZY; Zhang, YT, 2014) |
"Vascular calcification is a phenomenon of disturbed calcium deposition, as part of the calcium that is supposed to be deposited to our bones, is lodged to our vessels." | ( Pikilidou, MI; Scuteri, A; Yavropoulou, MP, 2014) |
"Vascular calcification is highly prevalent in end-stage renal disease and independently predictive of future cardiovascular events and mortality." | ( Chonchol, M; Jablonski, KL, 2013) |
"Vascular calcification is associated with significant cardiovascular morbidity and mortality, and has been demonstrated as an actively regulated process resembling bone formation." | ( Chen, Y; Liao, L; Lu, L; Song, Y; Wang, S; Wu, W; Ye, M; Yu, H; Zhou, Q, 2013) |
"Vascular calcification is a prominent feature of many diseases, including atherosclerosis, and it has emerged as a powerful predictor of cardiovascular morbidity and mortality." | ( Huang, K; Li, X; Liu, H; Qin, F, 2014) |
"Vascular calcification is common among patients undergoing dialysis and is associated with mortality." | ( Coresh, J; Crainiceanu, C; Jaar, BG; Kao, WH; Oberai, PC; Parekh, RS; Plantinga, LC; Powe, NR; Scialla, JJ; Shafi, T; Sozio, SM, 2014) |
"Vascular calcification is highly prevalent in patients with chronic kidney disease (CKD) and contributes to increased risk of cardiovascular disease and mortality." | ( Cao, H; Dai, C; Fang, L; He, W; Jiang, L; Su, W; Wen, P; Xu, H; Yang, J; Ye, H; Zhou, Y, 2014) |
"Medial vascular calcification is a specific complication in chronic kidney disease (CKD) patients although its pathogenesis is poorly understood." | ( Hamada, C; Seto, T; Tomino, Y, 2014) |
"Vascular calcification is an actively regulated process that culminates in organized extracellular matrix mineral deposition by osteoblast-like cells." | ( Cao, X; Chen, A; Guo, F; Li, C; Pang, L; Shi, C; Wan, M; Wang, W, 2014) |
"Vascular calcification is a major risk factor for cardiovascular diseases." | ( Huang, W; Liu, YS; Tan, P; Wang, S; Wang, Y; Wang, YJ; Zhan, JK, 2014) |
"Vascular calcification is a serious cardiovascular complication that contributes to the increased morbidity and mortality of patients with diabetes mellitus." | ( Bradley, WE; Chatham, JC; Chen, Y; Dell'Italia, LJ; Heath, JM; Litovsky, S; Sun, Y; Wu, H; Yuan, K, 2014) |
"Vascular calcification is highly correlated with increased cardiovascular morbidity and mortality." | ( Feng, H; Lei, H; Li, H; Li, L; Wang, C; Wang, JY; Wu, D; Wu, LL; Zhou, Y, 2014) |
"Vascular calcification is highly correlated with cardiovascular disease morbidity and mortality." | ( Callegari, A; Coons, ML; Ricks, JL; Rosenfeld, ME; Scatena, M, 2014) |
"Vascular calcification is an active process in which vascular smooth muscle cells (VSMCs) adopt an osteoblastic phenotype and deposit hydroxyapatite crystals; apoptosis of VSMCs also promotes this deposition." | ( DiNicolantonio, JJ; McCarty, MF, 2014) |
"Vascular calcifications are a hallmark of advanced cardiovascular disease in patients with chronic kidney disease." | ( Freise, C; Querfeld, U, 2014) |
"Vascular calcification is the leading cause of cardiovascular diseases in chronic kidney disease (CKD) patients." | ( Cai, Y; He, D; Liu, XF; Wang, X; Xu, MJ, 2014) |
"Vascular calcification is a strong predictor of cardiovascular morbidity and mortality, especially in individuals with chronic kidney disease or diabetes." | ( Jeong, D; Kim, H; Lee, K, 2014) |
"Vascular calcification is an active, highly regulated process that shares many similarities with normal bone formation." | ( Giachelli, CM; Paloian, NJ, 2014) |
"Vascular calcification is frequently found already in early stages of chronic kidney disease (CKD) patients and is associated with high cardiovascular risk." | ( Alesutan, I; Lang, F; Ritz, E; Voelkl, J, 2014) |
"Cardiovascular calcification is well known as an important factor for poor prognosis in CKD patients." | ( Hayashi, T; Joki, N, 2014) |
"Vascular calcification is associated with increased risk of morbidity and mortality in patients with cardiovascular diseases, chronic kidney diseases, and diabetes." | ( Ahn, Y; Cho, JG; Cho, SN; Choi, SY; Hong, YJ; Jeong, MH; Kee, HJ; Kim, GR; Kim, IK; Park, HW; Park, JC; Ryu, Y, 2014) |
"Vascular calcification is an unfavorable event in the natural history of atherosclerosis that predicts cardiovascular morbidity and mortality." | ( Blasetti Fantauzzi, C; Iacobini, C; Menini, S; Pugliese, G, 2015) |
"Vascular calcification is a risk factor for causing cardiovascular events and has a high prevalence among chronic kidney disease (CKD) patients." | ( Fan, X; Feng, JM; Liu, LL; Ma, JF; Ren, C; Sun, L; Sun, W; Sun, YT; Wang, LN; Xu, TH; Yao, L, 2015) |
"Cardiovascular calcification is both a risk factor and contributor to morbidity and mortality." | ( Brandenburg, V; Floege, J; Reutelingsperger, C; Schlieper, G; Schurgers, L, 2016) |
"Vascular calcification is an independent risk factor for the development of cardiovascular disease and is classified into two types based on the site of calcification : intimal atherosclerotic calcification and Mönckeberg's medial calcification." | ( Shioi, A, 2015) |
"Vascular calcification is known to be an important risk factor influencing mortality in CKD patients." | ( Fukagawa, M; Kakuta, T; Omata, M, 2015) |
"Vascular calcification is commonly seen with aging, chronic kidney disese (CKD), diabetes, and atherosclerosis, and is closely associated with cardiovascular morbidity and mortality." | ( Kurabayashi, M, 2015) |
"Vascular calcification is a risk factor for cerebral and cardiovascular events and has a high prevalence among elderly." | ( Akishita, M; Akiyoshi, T; Ogawa, S, 2015) |
"Vascular calcification is the abnormality in chronic kidney disease-mineral bone disorder (CKD-MBD) that directly affects the prognosis in relation with cardiovascular diseases." | ( Hanafusa, N, 2015) |
"Vascular calcification is prevailing in patients suffering from diabetes mellitus and/or chronic kidney disease, and carries a poor prognosis." | ( Kurozumi, A; Nakano, K; Okada, Y; Tanaka, Y, 2015) |
"Vascular calcification is very common in patients with end-stage renal disease (ESRD) and has been found to be associated with mineral and bone disorders." | ( Nitta, K; Ogawa, T, 2015) |
"Vascular calcification is a complex biological process that is a hallmark of atherosclerosis." | ( Bennett, MR; Bird, JL; Brindle, KM; Davenport, AP; Dweck, MR; Gallagher, FA; Irkle, A; Joshi, FR; Lewis, DY; Newby, DE; Rudd, JH; Skepper, JN; Vesey, AT; Warburton, EA, 2015) |
"Vascular calcification is a frequent cause of morbidity and mortality in patients with CKD and the general population." | ( Cannata-Andía, JB; Carrillo-López, N; Fernández-Martín, JL; Martínez-Arias, L; Naves-Díaz, M; Panizo, S; Rodríguez, I; Ruiz-Torres, MP, 2016) |
"Vascular calcification is a common complication associated with chronic kidney disease and the major cause of cardiovascular disease in patients with end-stage renal disease." | ( Liu, ZH, 2015) |
"Vascular calcification is an independent risk factor for cardiovascular disease." | ( Hirata, K; Rikitake, Y; Satomi-Kobayashi, S; Terao, Y, 2015) |
"Cardiovascular calcification is prevalent in the aging population and in patients with chronic kidney disease (CKD) and diabetes mellitus, giving rise to substantial morbidity and mortality." | ( Chatrou, ML; Horn, P; Kelm, M; Potthoff, SA; Scheiber, D; Schurgers, LJ; Veulemans, V; Westenfeld, R, 2015) |
"Vascular calcification is known to reduce the elasticity of aorta." | ( Azechi, T; Sato, F; Sudo, R; Wachi, H, 2015) |
"Vascular calcification is a frequent complication of atherosclerosis, diabetes and chronic kidney disease." | ( Agarwal, A; Arosio, P; Balla, G; Balla, J; Balogh, E; Bányai, E; Becs, Á; Becs, G; Eaton, JW; Jeney, V; Kovács, KÉ; Nyitrai, M; Poli, M; Zarjou, A, 2016) |
"Vascular calcification is a characteristic feature of aging, atherosclerosis, diabetes mellitus, and end-stage renal disease." | ( Akishita, M; Akiyoshi, T; Iijima, K; Kahyo, T; Ogawa, S; Ota, H; Ouchi, Y; Setou, M; Son, BK, 2016) |
"This increase in vascular calcification is due to inhibition of the enzyme matrix gamma-carboxyglutamate Gla protein (MGP)." | ( Goldhaber, SZ; Poterucha, TJ, 2016) |
"Vascular calcification is an important risk factor associated with mortality among patients with chronic kidney disease." | ( Dai, W; Diao, Z; Guo, W; Han, X; Liu, S; Liu, W, 2016) |
"Vascular calcification is a common feature of major cardiovascular diseases." | ( Aikawa, E; Aikawa, M; Goettsch, C; Hagita, S; Hutcheson, JD; Iwata, H; Kjolby, M; Kramann, R; Libby, P; Michel, T; Nykjaer, A; Pham, T; Rader, DJ; Rogers, M; Shibasaki, M; Singh, SA, 2016) |
"Vascular calcification is prevalent in clinical states characterized by low-grade chronic inflammation, such as chronic kidney disease (CKD)." | ( Aghagolzadeh, P; Bachtler, M; Bijarnia, R; Jackson, C; Odermatt, A; Pasch, A; Radpour, R; Smith, ER, 2016) |
"Medial vascular calcification is a common complication of chronic kidney disease (CKD)." | ( Agharazii, M; Cornfield, DN; Gobeil, S; Lamalice, L; Larivière, R; Mokas, S; Richard, DE, 2016) |
"Vascular calcification is an active process of osteoblastic differentiation of vascular smooth muscle cells; however, its definite mechanism remains unknown." | ( Chen, XJ; Liang, QH; Ma, YY; Song, M; Sun, L; Wang, N; Wang, YZ; Yi, PF; Zhang, B, 2016) |
"Vascular calcification is one of the major complications of cardiovascular disease and is an independent risk factor for myocardial infarction and cardiac death." | ( Akishita, M; Hashizume, T; Nanao-Hamai, M; Ogawa, S; Son, BK, 2016) |
"Pathologic vascular calcification is a significant reason for mortality and morbidity in patients who suffer from end-stage renal disease (ESRD)." | ( Du, Y; Li, G; Li, Y; Wang, L; Zhang, P; Zhou, F, 2016) |
"Vascular calcification is a strong independent predictor of increased cardiovascular morbidity and mortality and has a high prevalence among patients with chronic kidney disease." | ( Chang, X; Cong, G; Cui, L; Hao, L; Li, Z, 2017) |
"Vascular calcification is a characteristic feature of atherosclerosis and is considered as an independent predictor of cardiovascular risk." | ( Bangash, AB; Chen, Y; Shao, C; Song, J; Wang, C; Wang, Z; Yan, J; Zhong, W, 2017) |
"Vascular calcification is initiated by exosomes, and proteomic analysis revealed that VSMC exosomes are loaded with Gla-containing coagulation factors: IX and X, PT (prothrombin), and proteins C and S." | ( Hackeng, TM; Harrison, P; Heiss, A; Jahnen-Dechent, W; Kapustin, AN; McNair, R; Reynolds, JL; Schlieper, G; Schoppet, M; Schurgers, LJ; Shanahan, CM, 2017) |
"Vascular calcification is a risk predictor and common pathological change in cardiovascular diseases that are associated with elastin degradation and phenotypic transformation of vascular smooth muscle cells via gelatinase matrix metalloproteinase-2 (MMP2)." | ( Han, C; Jiang, W; Lin, Q; Qin, X; Yang, H; Zhang, Z, 2017) |
"Vascular calcification is commonly seen in elderly people, though it can also appear in middle-aged subjects affected by premature vascular aging." | ( Alique, M; Bodega, G; Bohórquez, L; Carmona, A; Carracedo, J; Luna, C; Luque, R; Noci, MV; Ramírez, R; Ruíz-Torres, MP; Troyano, N, 2017) |
"Cardiovascular calcification is one of the most severe outcomes associated with cardiovascular disease and often results in significant morbidity and mortality." | ( Cao, R; Chen, L; Liu, C; Liu, J; Shen, Y; Tang, Z; Wu, Y; Xiao, X; Xu, C; Zhang, Q; Zhao, H; Zhao, Q; Zheng, Y; Zhong, J; Zu, X, 2017) |
"Vascular calcification is a common feature in atherosclerosis and associates with cardiovascular events." | ( Beloqui, O; Cortés, A; Díez, J; Fortuño, A; Landecho, MF; Moreno, MU; Pejenaute, Á; San José, G; Zalba, G, 2017) |
"Vascular calcification is associated with increased risk of myocardial infarction and stroke." | ( Handelsman, DJ; Heather, AK; Hughes, G; Liong, EC; McGrath, KCY; McRobb, LS; Tan, JTM; Tsatralis, T, 2017) |
"Vascular calcification is driven by aldosterone-sensitive osteogenic transformation of vascular smooth muscle cells (VSMCs)." | ( Alesutan, I; Borst, O; Castor, T; Feger, M; Gawaz, M; Kratschmar, DV; Kuro-O, M; Lang, F; Leibrock, C; Mia, S; Odermatt, A; Pieske, B; Pilz, S; Sacherer, M; Tomaschitz, A; Viereck, R; Voelkl, J; Wagner, CA, 2017) |
"Vascular calcification is actively regulated by inductive and inhibitory mechanisms (including vascular smooth muscle cell adaptation) and results from an active osteogenic process." | ( Ait-Mohand, K; Ausseil, J; Boullier, A; Cornu, M; Courtois, J; Da Nascimento, S; Darwiche, W; Elboutachfaiti, R; Gomila, C; Hodroge, A; Kamel, S; Kovensky, J; Lorne, E; Mansour, A; Massy, ZA; Petit, E; Rossi, C; Schembri, C; Sonnet, P; Toumieux, S; Trécherel, E; Verissimo, T, 2017) |
"Vascular calcification is established to be a critical factor in diabetes mellitus, which causes cardiovascular and amputation complication of diabetic patients." | ( Bao, Z; Li, L; Sun, Z; Wang, Z; Xu, L; Xu, S; Yan, J; Ye, F; Zhu, J, 2017) |
"Vascular calcifications are associated with nephrolithiasis." | ( Calle, J; Monga, M; Patel, ND; Remer, EM; Ward, RD, 2017) |
"Vascular calcification is a different process, stringently regulated mainly by local factors, in which osteoblast-like cells accumulate in the muscular layer of arteries ultimately taking on the physiological appearance of bone." | ( Siltari, A; Vapaatalo, H, 2018) |
"Vascular calcification is prevalent and associated with adverse outcome without available therapy." | ( Cao, F; Cao, X; Fu, K; Liu, J; Liu, X; Shen, F; Wang, S; Zhao, Y, 2017) |
"Vascular calcification is common among patients with chronic kidney disease (CKD), and it is associated with all-cause and cardiovascular disease mortality." | ( Block, G; Chonchol, M; Isakova, T; Jovanovich, A; Miyazaki, M; Smits, G; Stubbs, J, 2018) |
"Vascular calcification is a frequent complication in chronic haemodialysis patients and is associated with adverse outcomes." | ( Azpiazu, D; Egido, J; González-Parra, E; Ortiz, A; Villa-Bellosta, R, 2017) |
"Vascular calcification is a common health problem related to oxidative stress, inflammation, and circulating calciprotein particles (CPP)." | ( Aghagolzadeh, P; Bachtler, M; Feelisch, M; Lister, A; Odermatt, A; Pasch, A; Radpour, R; Smith, ER; van Goor, H, 2017) |
"Vascular calcification is a tightly regulated process that increases during ageing and occurs mainly in patients with diabetes and chronic renal failure." | ( Liberman, M; Marti, LC, 2017) |
"Vascular calcification is common and may affect cardiac function in patients with end-stage renal disease (ESRD)." | ( Cho, A; Choi, MJ; Jeon, HJ; Kim, EJ; Lee, YK; Noh, JW; Oh, J; Rhee, SY; Ryu, J; Shin, DH; Yoon, JW, 2017) |
"Vascular calcification is a risk factor that predicts adverse cardiovascular complications of several diseases including atherosclerosis." | ( Agarwal, A; Bradley, WE; Byon, CH; Chen, Y; Dell'Italia, LJ; Sanders, PW; Sun, Y; Wu, H; Yang, Y, 2017) |
"Vascular calcification is a major cause of morbidity and mortality." | ( Borland, SC; Borland, SJ; Canfield, AE; Francis, SE; Merry, CLR; Morgan, MR; Morris, TG, 2017) |
"Vascular calcification is one of the most important factors for high morbidity and mortality from cardiovascular and cerebrovascular diseases." | ( Dai, SL; Shang, YQ; Wang, XC; Wu, W; Yi, F, 2017) |
"Vascular calcification is a serious complication of chronic kidney disease, but the current therapeutic strategy is insufficient for preventing its progression." | ( Fukagawa, M; Hamano, N; Komaba, H, 2017) |
"Vascular calcification is the deposition of mineral in the artery wall by vascular smooth muscle cells (VSMCs) in response to pathological stimuli." | ( Borland, SJ; Canfield, AE; Clarke, CJ; Hannun, YA; Morris, TG; Ohanian, J; Ohanian, V; Wilson, C, 2018) |
"Vascular calcification is related to vascular diseases, for example, atherosclerosis, and its comorbidities, such as diabetes and chronic kidney disease." | ( Faggioli, G; Pasquinelli, G; Zazzeroni, L, 2018) |
"Vascular calcification is highly prevalent in end-stage renal disease (ESRD) and is a significant risk factor for future cardiovascular events and death." | ( Chang, WJ; Chen, YY; Li, SY; Tsai, MT, 2018) |
"Vascular calcification is an important risk factor for cardiovascular disease, and is closely associated with all-cause mortality." | ( Barinda, AJ; Emoto, N; Hirata, KI; Ikeda, K, 2017) |
"Vascular calcification is a pathologic response to mineral imbalances and is prevalent in atherosclerosis, diabetes mellitus, and chronic kidney disease." | ( Cai, Y; Flores, AM; Guzman, RJ; Lin, T; Wang, XL, 2018) |
"Vascular calcification is prevalent in patients with atherosclerosis, and oxidative stress promotes pathogenesis of atherosclerosis." | ( Bradley, WE; Chen, J; Chen, Y; Dell'Italia, LJ; Sun, Y; Wu, H; Yang, Y, 2018) |
"Pathologic cardiovascular calcification is associated with a number of conditions and is a common complication of chronic kidney disease." | ( O'Neill, WC; Villa-Bellosta, R, 2018) |
"While vascular calcification is an important factor regulating prognosis in dialysis patients, its components have not been adequately studied." | ( Higuchi, C; Nakaoka, T; Nishizawa, Y; Nitta, K; Ogawa, T; Omori, H; Sakura, H, 2018) |
"Vascular calcification is associated with increased cardiovascular morbidity and mortality in patients with atherosclerosis, diabetes and chronic kidney disease." | ( Ashton, N; Borland, SJ; Canfield, AE; Eyre, HJ; Gilmore, A; Hyde, GD; Inkson, CA; Kalra, PA; Pond, E; Ponnusamy, A; Sinha, S; Taylor, RF, 2018) |
"Vascular calcification is a main cause of increased cardiovascular morbidity and mortality in chronic kidney disease (CKD) patients." | ( Gan, L; Li, L; Lin, J; Liu, Q; Ou, S; Wei, X; Wu, W, 2018) |
"Vascular calcification is extremely common and associated with major adverse cardiovascular events." | ( Cao, F; Liu, J; Liu, S; Liu, X; Mi, Y, 2018) |
"Vascular calcification is common in patients with end-stage renal disease (ESRD)." | ( Nitta, K; Ogawa, T, 2018) |
"Uremic vascular calcification is a regulated cell-mediated process wherein cells in the arterial wall transdifferentiate to actively calcifying cells resulting in a process resembling bone formation." | ( Gravesen, E; Høgdall, E; Kjær, A; Lewin, E; Mace, M; Morevati, M; Nielsen, C; Nordholm, A; Olgaard, K, 2018) |
"Cardiovascular calcification is still a major burden for patients with chronic kidney disease (CKD)." | ( Schlieper, G, 2018) |
"Vascular calcification is widespread and clinically significant, contributing to substantial morbidity and mortality." | ( Chen, R; Li, B; Shao, C; Wang, CP; Wang, ZQ; Xu, Y; Yan, JC; Yang, P; Zhong, W, 2018) |
"Vascular calcification is a pathologic phenomenon consisting of calcium phosphate crystal deposition in the vascular walls." | ( Azpiazu, D; Gonzalo, S; Villa-Bellosta, R, 2019) |
"Vascular calcification is common in chronic kidney disease (CKD) patients, while erythropoietin (EPO) is widely used in the treatment of renal anemia in CKD patients, whether there is a link between the two is still not clear." | ( Gan, H; He, J; Zhao, L; Zhong, X, 2019) |
"Vascular calcification is a common finding in atherosclerosis and in patients with chronic kidney disease." | ( Bai, HY; Higaki, A; Higaki, J; Horiuchi, M; Iwanami, J; Kan-No, H; Kukida, M; Min, LJ; Mogi, M; Okura, T; Shan, BS; Tsukuda, K; Yamauchi, T, 2019) |
"Vascular calcification is a critical complication in patients with chronic kidney disease (CKD) because it is predictive of cardiovascular events and mortality." | ( Chen, R; Chen, RM; Hou, YC; Lin, YF; Liu, WC; Lu, CL; Lu, KC; Yen, TH; Zheng, CM, 2019) |
"Vascular calcification is a common complication in patients with chronic kidney disease (CKD)." | ( Bao, S; Diao, Z; Guo, W; Guo, Y; Han, X; Liu, W; Wang, L, 2019) |
"Vascular calcification is highly prevalent in end-stage renal diseases and is predictive of cardiovascular events and mortality." | ( An, J; Huang, K; Li, Y; Liang, M; Tong, Q; Wang, C; Xu, W; Zhang, F, 2019) |
"Vascular calcification is characterized by the accumulation of hydroxyapatite crystals, which is a result of aberrant mineral metabolism." | ( Choe, N; Jeong, G; Kim, J; Kim, YK; Kook, H; Kwon, DH; Lim, YH; Park, WJ; Ryu, J; Shin, S, 2019) |
"Vascular calcification is a major contributor to increased cardiovascular mortality in chronic kidney disease (CKD)." | ( de Baaij, JHF; Zeper, LW, 2019) |
"Objective- Vascular calcification is associated with high risk of cardiovascular events and mortality." | ( Balogh, E; Jeney, V; Méhes, G; Paragh, G; Tóth, A; Trencsényi, G, 2019) |
"Vascular calcification is a complication of diseases and conditions such as chronic kidney disease, diabetes, and aging." | ( Enaka, M; Muragaki, Y; Wei, R, 2019) |
"Cardiovascular calcification is associated with cardiovascular morbidity and mortality of patients with end-stage renal diseases (ESRD)." | ( Guo, L; Han, L; Lv, L; Wang, D; Wang, J; Xu, D; Xu, Y; Yin, Z; Zeng, F; Zhou, H, 2019) |
"Vascular calcification is a recognised source of morbidity among mid-age and elderly subjects." | ( Cochran, M, 2019) |
"Vascular calcification is a common problem in the elderly with diabetes, heart failure and end-stage renal disease." | ( Guo, B; Jia, Y; Lu, Y; Ma, Y; Sun, J; Wang, R; Wei, R, 2019) |
"Vascular calcification is an independent predictor of cardiovascular disease, and therefore, inhibition or regression of this processes is of clinical importance." | ( de Leeuw, PW; Kroon, AA; Schurgers, LJ; Vossen, LM, 2019) |
"Vascular calcification is highly prevalent in patients with chronic kidney disease." | ( Chen, M; Chen, Y; Li, Y; Li, Z; Liu, H; Liu, X; Lu, L; Ou, C; Yan, J; Yang, P; Zhang, X; Zhong, X, 2020) |
"Vascular calcification is a life-threatening complication in patients with chronic kidney disease." | ( Fukagawa, M; Komaba, H; Nakagawa, Y, 2020) |
"Vascular calcification is intimately associated with CV events and mortality and is a chronic inflammatory process in which activated macrophages promote osteoblastic differentiation of vascular smooth muscle cells (VSMCs) through the production of proinflammatory cytokines such as IL-1β, IL-6, TNF-α, and oncostatin M (OSM) in both intimal and medial layers of arterial walls." | ( Emoto, M; Morioka, T; Shioi, A; Shoji, T, 2020) |
"Vascular calcification is commonly observed in atherosclerosis and diabetes." | ( Hu, Z; Li, M; Li, S; Shao, J; Wang, Z; Xia, H; Yu, L, 2020) |
"Vascular calcification is the pathological deposition of calcium/phosphate in the vascular system and is closely associated with cardiovascular morbidity and mortality." | ( Bae, MK; Bae, SK; Hwang, JJ; Kim, HJ; Kim, MK; Kim, Y; Park, HJ, 2020) |
"Vascular calcification is a severe pathological event in the manifestation of atherosclerosis." | ( Babel, N; Claeys, L; Geißler, S; Pustlauk, W; Roch, T; Westhoff, TH, 2020) |
"Vascular calcification is a commonly occurring pathological process and is recognized as an independent prognostic marker for cardiovascular morbidity and mortality." | ( Hansen, KC; Hill, RC; Johnson, SL; Lee, HS; Syedain, ZH; Thrivikraman, G; Tranquillo, RT, 2020) |
"Vascular calcification is a recognized predictor of cardiovascular risk in the diabetic patient, with DNA damage and accelerated senescence linked to oxidative stress-associated pathological calcification." | ( Alexander, MY; Bartoli-Leonard, F; Schiro, A; Serracino Inglott, F; Weston, R; Wilkinson, FL, 2021) |
"Vascular calcification is a highly regulated process similar to osteogenesis involving phenotypic change of vascular smooth muscle cells (VSMCs)." | ( Chen, A; Chen, Y; Dong, Q; Fu, M; Li, Y; Liu, W; Liu, X; Lu, L; Ou, JS; Wang, S; Yan, J; Yang, X, 2020) |
"Vascular calcification is a common complication in patients with chronic kidney disease and associated with increased morbidity and mortality." | ( Kuo, WH; Lee, CT; Lee, YT; Leung, FF; Ng, HY; Tain, YL, 2020) |
"Vascular calcification is a known complication of chronic kidney disease (CKD)." | ( Grewal, R; Le, TH; Levy, DS, 2020) |
"Vascular calcification is an important risk factor for the mortality and morbidity in chronic kidney disease (CKD)." | ( Chen, J; Kong, X; Lu, Y; Shen, Y; Sheng, Y; Su, Z; Sun, W; Yang, C; Yang, S; Zong, P, 2020) |
"Vascular calcification is common among aging populations and mediated by vascular smooth muscle cells (VSMCs)." | ( Ahmad, S; Bordoloi, J; Furmanik, M; Kapustin, A; Schurgers, LJ; Shanahan, CM; van Gorp, R; Whitehead, M, 2021) |
"Vascular calcification is the pathological precipitation of phosphate and calcium in the vasculature and is closely associated with increased cardiovascular risk and mortality." | ( Bae, MK; Bae, SK; Kim, HJ; Kim, MK; Kim, Y; Park, HJ; Park, HR, 2020) |
"Vascular calcification is a prognostic marker for cardiovascular mortality in chronic kidney disease (CKD) patients." | ( de Baaij, JHF; Hoenderop, JGJ; Ter Braake, AD; Vervloet, MG, 2022) |
"Vascular calcification is an independent risk factor for cardiovascular diseases and all-cause mortality in end stage renal disease, and particularly in hemodialysis patients." | ( Alshahawey, M; El Borolossy, R; El Wakeel, L; Elsaid, T; Sabri, NA, 2021) |
"Vascular calcification is a severe complication that increases the all-cause mortality of cardiovascular disease but lacks medical therapy." | ( Boström, KI; Cai, X; Ma, JA; Qiao, X; Wu, X; Yao, J; Yao, Y; Zhang, D; Zhang, L, 2021) |
"Vascular calcification is a common and important cardiovascular risk factor in patients with chronic kidney disease (CKD)." | ( Lees, JS; Mark, PB; Witham, MD, 2021) |
"Vascular calcification is a common pathologic condition in patients with chronic kidney disease (CKD) and aging individuals." | ( Chen, A; Chen, Y; Dong, Q; Fu, M; Lan, Z; Li, Y; Liang, Q; Liu, X; Lu, L; Ou, JS; Wang, S; Yan, J; Yang, P; Yang, X; Ye, Y, 2021) |
"Vascular calcification is common in chronic kidney disease; however, the extent to which such condition can affect the renal microvasculature and the neighboring cell types is unclear." | ( Awuah Boadi, E; Bandyopadhyay, BC; Shin, S, 2021) |
"Vascular calcification is very commonly observed in patients with chronic kidney disease (CKD), but there is no efficient therapy available." | ( Chen, A; Dong, Q; Fu, M; Lan, Z; Li, Y; Liang, Q; Liu, X; Lu, L; Ou, JS; Wang, S; Yan, J; Yang, X; Ye, Y, 2021) |
"Vascular calcification is a major risk factor for cardiovascular disease and accounts for a large proportion of deaths from cardiovascular disease in patients with chronic kidney disease." | ( Tang, N; Zhang, Y; Zhou, J, 2021) |
"Vascular calcification is an active process that increases cardiovascular disease (CVD) risk." | ( Akbulut, AC; Biessen, EAL; Brandenburg, V; Dzhanaev, R; Floege, J; Jahnen-Dechent, W; Jaminon, AMG; Kramann, R; Mees, B; Rapp, N; Reutelingsperger, CP; Schurgers, LJ; Temmerman, L; Uitto, J, 2021) |
"Cardiovascular calcification is the ectopic deposition of calcium-phosphate crystals within the arterial wall and the aortic valve leaflets." | ( Cinetto, F; Donato, M; Faggin, E; Felice, C; Ferri, N; Lupo, MG; Rattazzi, M, 2021) |
"Vascular calcification is highly prevalent in chronic kidney disease (CKD), and is characterized by transdifferentiation from contractile vascular smooth muscle cells (VSMCs) into an osteogenic phenotype." | ( Chen, M; Feng, L; Li, Z; Ou, C; Que, D; Wei, J; Yan, J; Yang, P; Zhang, X; Zhong, X, 2021) |
"Vascular calcification is the heterotopic accumulation of calcium phosphate salts in the vascular tissue and is highly correlated with increased cardiovascular morbidity and mortality." | ( Bae, MK; Bae, SK; Kim, HJ; Kim, MK; Kim, Y; Park, HJ, 2021) |
"Vascular calcification is common in chronic kidney disease (CKD) and associated with increased cardiovascular mortality." | ( Alesutan, I; Auer, T; Buehling, SS; Degenhart, G; Feger, M; Grebe, S; Hammer, F; Hauser, T; Krane, V; Lang, F; Malzahn, U; Masyout, J; Pasch, A; Tuffaha, R; Voelkl, J; Wanner, C, 2021) |
"Vascular calcification is one of the most prevalent disorders in pediatric hemodialysis patients that eventually lead to cardiovascular morbidity." | ( El Borolossy, R; El-Farsy, MS, 2022) |
"Development of vascular calcification is accelerated in patients with end-stage renal disease." | ( Aaltonen, L; Koivuviita, N; Kröger, H; Löyttyniemi, E; Metsärinne, K; Seppänen, M; Tong, X, 2022) |
"Vascular calcification is a major manifestation of cardiovascular disease in advanced chronic kidney disease and is inhibited by vitamin K-dependent proteins." | ( Lees, JS; Mark, PB, 2022) |
"Vascular calcification is a key process involved in cardiovascular morbidity and mortality in patients with chronic kidney disease (CKD)." | ( Bos, C; Hoekstra, T; Hoenderop, JGJ; Leenders, NHJ; Schurgers, LJ; Vervloet, MG, 2022) |
"Vascular calcification is one of the most common complications of chronic kidney disease (CKD), which is closely associated with increased mortality and morbidity rates of CKD patients." | ( Chen, X; Duan, S; Guo, W; Liu, W; Liu, Y, 2022) |
"Vascular calcification is associated with cardiovascular morbidity and mortality in people with CKD." | ( Ruderman, I; Smith, ER; Tiong, MK; Toussaint, ND; Xu, C, 2022) |
"Vascular calcification is an important contributor to morbidity and mortality in many pathologies, including chronic kidney disease, diabetes mellitus, and atherosclerosis." | ( Akbulut, AC; Dzhanaev, R; Jahnen-Dechent, W; Jaminon, AMG; Rapp, N; Reutelingsperger, CP; Schurgers, LJ, 2022) |
"Vascular calcification is commonly observed in chronic kidney disease (CKD) and is associated with increased morbidity and mortality." | ( Kuo, WH; Lee, CT; Lee, WC; Tain, YL; Wang, Y, 2022) |
"Vascular calcification is a risk factor for cardiovascular and kidney diseases." | ( Argilés, À; Cortijo, I; Duranton, F; Gayrard, N; Jover, B; Laget, J; Muyor, K, 2022) |
"Vascular calcification is an actively regulated process resembling bone formation and contributes to the cardiovascular morbidity and mortality of chronic kidney disease (CKD)." | ( Chen, A; Dong, Q; Fu, M; Lan, Z; Li, L; Li, Y; Liang, Q; Liu, X; Lu, L; Ou, JS; Qiu, X; Wang, S; Yan, J; Ye, Y; Zhu, Z, 2022) |
"Vascular calcification is a process similar to bone formation, which is highly adjustable and active." | ( Chu, H; Li, Y; Mu, Y; Pan, Y; Sun, J; Wang, L; Wang, X, 2022) |
"Vascular calcification is a known risk factor for cardiovascular events and mortality in patients with chronic kidney disease (CKD)." | ( Bjergfelt, SS; Bro, S; Christoffersen, C; Feldt-Rasmussen, B; Hjortkjær, HØ; Kofoed, KF; Lange, T; Sørensen, IMH, 2023) |
"Vascular calcification is associated with aging, type 2 diabetes, and atherosclerosis, and increases the risk of cardiovascular morbidity and mortality." | ( Caporali, A; Corcoran, BM; Forsythe, RO; Jones, RA; Koo, E; MacRae, VE; Phadwal, K; Tang, K; Tang, Q, 2022) |
"Vascular calcification is commonly observed in chronic kidney disease." | ( Chang, K; Chen, S; Jiang, L; Li, J; Li, Y; Liao, R; Qin, Z; Su, B; Yang, Q; Zhang, Z, 2022) |
"Vascular calcification is an important risk factor for cardiovascular events, accompanied by DNA damage during the process." | ( Chen, A; Dong, Q; Fu, M; Lan, Z; Li, L; Li, Y; Liang, Q; Liu, X; Lu, L; Ou, JS; Wang, S; Yan, J; Ye, Y, 2022) |
"Vascular calcification is a common pathological change of cardiovascular tissues in patients with chronic kidney disease, diabetes, hypertension and atherosclerosis." | ( Chen, JX; Chen, JY; Li, DY; Tan, X; Wang, SY; Wang, YH; Xie, YC; Zhong, H; Zhu, DX, 2022) |
"Although vascular calcification is a recognised complication for haemodialysis patients, peritoneal dialysis (PD) patients are also at risk." | ( Davenport, A, 2023) |
"The prevention of vascular calcification is important to improve the prognosis of such patients." | ( Araki, SI; Ishida, K; Kawakami, K; Kobashi, S; Nakashima, Y; Ohya, M; Shigematsu, T; Sonou, T; Tanaka, Y; Yamamoto, S; Yano, T; Yashiro, M, 2023) |
"Vascular calcification is recognized as the advanced stage of atherosclerosis burden." | ( Gaj, S; Kovi, S; Man, S; Nakamura, K; Shimoyama, T; Uchino, K, 2023) |
"Vascular calcification is accelerated in patients with diabetes mellitus and increases risk of cardiovascular events and mortality." | ( Chen, Y; Sun, Y; Yang, Y; Zhang, W, 2023) |
"The pathogenesis of vascular calcification is incompletely understood, and until now, there have been no effective therapeutics for vascular calcification." | ( Li, P; Liu, R; Liu, Y; Shen, J; Sun, X; Wai Wong, VK; Wang, Q; Zhang, C; Zhao, M, 2023) |