Giant Cell Arteritis

A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)

Synonym
Giant Cell Arteritis

Excerpt	Reference
"Cranial Arteritis (Giant Cell Arteritis) is a clinical diagnosis supported by a raised erythrocyte sedimentation rate (ESR) and if required confirmed by a temporal artery biopsy."	( Dick, AD; Johnson, N; Millar, A, 1991)
"Giant cell arteritis is becoming recognized as one of the most common forms of vasculitis."	( Hunder, GG, 1990)
"Temporal arteritis (giant cell arteritis) is a disease of protean manifestation."	( Porter, MJ, 1990)
"Giant cell arteritis is an ophthalmic emergency because of imminent danger of bilateral total blindness, which is almost always preventable if the disease is quickly identified and treated urgently and aggressively."	( Hayreh, SS, 1990)
"Giant cell arteritis is a visually devastating disease that primarily affects the over 55 age group."	( Ishak, AW; Mitchell, PC; Persak, GC; Warwick, S, 1988)
"Giant cell arteritis is a disease of the elderly which is more common than previously recognized."	( Hunder, GG; Huston, KA, 1980)
"Giant cell arteritis is a systemic necrotizing vasculitis that often causes profound and irreversible visual loss in elderly individuals."	( Pollock, SC; Postel, EA, 1993)
"Giant cell arteritis is usually easy to recognize, easy to treat, and satisfying to manage."	( Bais, R; Kachroo, A; Panush, RS; Tello, C, 1996)
"Giant cell arteritis is a common cause of severe visual loss in older individuals."	( Barney, NP; Blumenkranz, MS; Boone, DE; Dieckert, JP; Folk, JC; Grand, MG; Melberg, NS; Stransky, TJ, 1995)
"Giant cell arteritis is a serious condition, requiring immediate treatment."	( Franklin, CD; Nixon, PP; Payne, M, 1997)
"Giant cell arteritis is a chronic granulomatous inflammation of unknown aetiology involving large and medium size arteries in the elderly."	( Goh, KY; Lim, TH, 2000)
"Giant cell arteritis is a T-cell dependent auto-immune vasculitis that involves a T-helper l (Th1) cell response."	( Gissot, V; Jauberteau, MO; Liozon, E; Loustaud, V; Soria, P; Vidal, E, 2000)
"Horton disease or 'giant cell arteritis' is a known entity in its typical form; the difficulty in diagnosis is due to the atypical signs and symptoms."	( Alexandre, C; Barouky, R; Becourt-Verlomme, C; Gonthier, R; Laurent, H; Rousset, H; Vital Durand, D, 2001)
"Giant cell arteritis is a systemic vasculitis that affects large- and medium sized arteries."	( Budrowski, R; Mariak, Z; Obuchowska, I, 2006)
"Giant cell arteritis is an important cause of blindness in patients over 60 years of age."	( Danesh-Meyer, HV; Savino, PJ, 2007)
"Giant cell arteritis is a medium- and large-vessel vasculitis, the most prevalent systemic vasculitis in subjects over age 60."	( Liozon, E; Ly, K, 2008)
"Giant cell arteritis is a granulomatous vasculitis of the aorta and its branches that causes blindness, stroke, and aortic aneurysm."	( Deng, J; Desai, M; Goronzy, JJ; Kubo, JT; Piggott, K; Warrington, K; Weyand, CM; Younge, B, 2011)
"Giant cell arteritis is a systemic, inflammatory, and vascular syndrome that requires early diagnosis and immediate management because of the risk of loss of vision."	( Evans, A; Greenhill, GA; Kennedy, DW, 2012)
"Giant cell arteritis is rarely recognized in Latin America."	( Alba, MA; Flores-Suárez, LF; Mena-Madrazo, JA; Reyes, E, 2012)
"Giant cell arteritis is a chronic vasculitis affecting large and medium-sized arteries, most commonly the temporal and other cranial arteries."	( Borchers, AT; Gershwin, ME, 2012)
"This case of giant cell arteritis is noteworthy because it evaded standard diagnostic criteria and only emerged as fever of unknown origin."	( Bettenworth, D; Brückner, M; Heidemann, J; Hengst, K; Weckesser, M; Willeke, P, 2014)
"Giant cell arteritis is a common cause of headache in patients aged more than 50 years."	( Joshi, Y; Nagasayi, S; White, S, 2014)
"Giant cell arteritis is an immune-mediated disease of medium and large-sized arteries that affects mostly people older than 50 years of age."	( Adler, S; Bütikofer, L; Dan, D; Fiege, V; Kuchen, S; Reichenbach, S; Seitz, M; Villiger, PM; Wermelinger, F, 2016)
"Giant cell arteritis is an inflammatory disorder of the medium- and large-size arteries."	( Borruat, FX; Buss, G; Mayer, C; Sokolov, AA; Spertini, F; Vionnet, J, 2017)
"Giant cell arteritis is a large-vessels vasculitis, which treatment consists in a slowly-tappered steroid-therapy."	( Arnaud, E; Broner, J, 2018)
"Giant cell arteritis is a common systemic vasculitis affecting the elderly, with maximum prevalence in the 7th decade of age, targeting aortic derived medium and large vessels of the neck and head."	( Badea, C; Băicuș, C; Chiriac, A, 2019)
"Giant cell arteritis is the most common primary systemic vasculitis in adults aged ≥50 years and peaks in the eighth decade of life."	( Biswas, S; Crooks, D; Fletcher, N; Healy, S; Huda, S; Jacob, A; Kitchen, WJ; Rathi, N; Sekhar, A; Simpson, M, 2019)
"Giant cell arteritis is a comorbidity of PMR."	( Ghetu, MV, 2020)
"Giant cell arteritis is not an uncommon disease, and its extension is furthermore finely assessed with new-generation PET/CT system."	( Bonnefoy, PB; Goutte, J; Habouzit, V; Jacquet-Francillon, N; Prevot, N, 2021)
"Giant cell arteritis is a large vessel vasculitis of the arteries in the head and neck."	( Kaul, A; Saha, P; Sofat, N; Srikantharajah, D, 2022)
"Giant cell arteritis is an inflammatory granulomatous arteritis predominantly involving large cerebral arteries."	( Lakmali, JPR; Madubashini, LADT; Perera, N, 2022)
"Giant cell arteritis is an inflammatory granulomatous arteritis predominantly involving large cerebral arteries."	( Lakmali, JPR; Madubashini, LADT; Perera, N, 2022)

Excerpt	Reference
"Two cases of giant cell arteritis affecting the breast are described and 11 previously described cases are reviewed."	( Guindi, M; Hill, DP; McKendry, RJ, 1990)

Excerpt	Reference
"The literature about the treatment of giant cell arteritis (GCA) is diverse and often includes patients with polymyalgia rheumatica (PMR) who do not have concurrent features of GCA."	( Hoffman, GS; Wilke, WS, 1995)
"Corticosteroids remain the cornerstone treatment of giant cell arteritis."	( Roblot, P, 1998)
"Clinicians who treat patients with giant cell arteritis (GCA) face many unresolved challenges."	( Cid, MC; Espígol-Frigolé, G; García-Martínez, A; Hernández-Rodríguez, J; Lozano, E, 2007)
"Glucocorticoids remain the mainstay of treatment of giant cell arteritis."	( Pipitone, N; Salvarani, C, 2008)
"Corticosteroids (CS) remain the main treatment for giant cell arteritis (GCA)."	( Bienvenu, B; Pugnet, G; Sailler, L, 2013)
"Patients with untreated active giant cell arteritis (GCA) are at high risk of permanent vision loss."	( Hellmich, B; Horvath, L, 2020)
"TREATMENT OF GIANT CELL ARTERITIS."	( Bonnotte, B; Greigert, H; Samson, M, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	512 (28.22)	23.3326
1990's	299 (16.48)	12.5806
2000's	375 (20.67)	18.1394
2010's	392 (21.61)	28.8240
2020's	236 (13.01)	9.53

Drug	Relationship Strength	Studies	Trials
ammonium hydroxide	low	1	0
salicylic acid	low	89	0
creatine	low	1	0
formaldehyde	low	2	0
dalteparin	low	2	0
histamine	low	4	0
niacin	low	1	0
nitrates	low	1	0
phosphorylcholine	low	1	0
pyridoxine	low	2	0
thiamine	low	1	0
urea	low	1	0
pk 11195	low	2	0
zopolrestat	low	1	0
acetaminophen	low	2	0
acetazolamide	low	5	0
alendronate	low	1	0
diatrizoic acid	low	1	0
amiodarone	low	1	0
amitriptyline	low	1	0
aspirin	low	61	0
azathioprine	medium	26	2
baclofen	low	2	0
carbamazepine	low	3	0
celecoxib	low	1	0
chlorambucil	low	1	0
chloroquine	low	2	0
chlorpromazine	low	1	0
ciprofloxacin	low	1	0
dapsone	low	21	0
diazepam	low	1	0
diclofenac	low	1	0
dipyridamole	low	1	0
erythrosine	low	4	0
etidronate	medium	2	2
etodolac	low	1	0
1-(5-isoquinolinesulfonyl)-2-methylpiperazine	low	1	0
fasudil	low	1	0
haloperidol	low	1	0
hydralazine	low	1	0
hydroxyurea	low	1	0
lidocaine	low	1	0
idebenone	low	1	0
imipramine	low	1	0
indomethacin	medium	8	1
isoniazid	low	1	0
2-propanol	low	3	0
leflunomide	low	12	0
lorglumide	low	1	0
nifedipine	low	1	0
nimesulide	low	1	0
nitroglycerin	low	4	0
norfloxacin	low	1	0
oxyphenbutazone	medium	2	1
papaverine	low	2	0
phenacetin	low	1	0
phenindione	low	2	0
phenylbutazone	low	4	0
potassium chloride	low	1	0
procainamide	low	1	0
procaine	low	4	0
proglumide	low	1	0
promethazine	low	1	0
propranolol	low	2	0
sulfasalazine	low	1	0
sulfinpyrazone	low	1	0
sulfobromophthalein	low	1	0
sumatriptan	low	4	0
ticlopidine	low	5	0
tolazoline	low	1	0
corticosterone	low	4	0
thymidine	low	1	0
hydroxyproline	low	1	0
thyroxine	low	2	0
methylprednisolone acetate	low	1	0
dehydroepiandrosterone	low	1	0
penicillin g	low	1	0
pilocarpine	low	2	0
aspartic acid	low	1	0
ethinyl estradiol	low	1	0
levodopa	low	1	0
tyrosine	low	1	0
methionine	low	1	0
17-alpha-hydroxyprogesterone	low	1	0
ampicillin	low	1	0
ornithine	low	1	0
valine	low	2	0
triamcinolone acetonide	low	1	0
methylprednisolone	medium	140	7
pyrroles	low	2	0
ergotamine	low	14	0
phenformin	low	1	0
meglumine	low	1	0
yohimbine	low	1	0
fluocortolone	low	2	0
isoxazoles	low	3	0
thiazoles	low	1	0
dexamethasone 21-phosphate	low	1	0
methysergide	low	5	0
betamethasone	low	3	0
fluorometholone	low	1	0
nandrolone	low	1	0
fluorobenzenes	low	1	0
homocystine	low	1	0
dextropropoxyphene	low	1	0
dihydroergotamine	low	1	0
hematoxylin	low	1	0
eosine yellowish-(ys)	low	1	0
gentian violet	low	1	0
congo red	low	1	0
dehydroepiandrosterone sulfate	low	2	0
ethylestrenol	low	1	0
ethambutol	low	1	0
d-alpha tocopherol	low	1	0
fluorescein	low	2	0
methylprednisolone hemisuccinate	low	3	0
streptomycin	low	2	0
cladribine	low	1	0
vidarabine	low	1	0
technetium	low	1	0
gadolinium	low	5	0
gold	low	2	0
trolamine salicylate	medium	54	1
clodronic acid	medium	1	1
tetradecanoylphorbol acetate	low	1	0
bromocriptine	low	1	0
glutamic acid	low	1	0
amoxicillin	low	1	0
etoposide	low	1	0
ribavirin	low	1	0
propiconazole	low	24	0
captopril	low	1	0
metsulfuron methyl	low	1	0
clopidogrel	low	3	0
atorvastatin	low	1	0
ibandronic acid	low	1	0
cephalosporin c	low	1	0
fluorodeoxyglucose f18	medium	223	9
zoledronic acid	low	2	0
dienogest	low	1	0
fibrinogen	low	12	0
pyridinoline	medium	1	1
deoxypyridinoline	medium	1	1
deramciclane	low	1	0
imatinib mesylate	low	2	0
acetaminophen, dextropropoxyphene, drug combination	low	1	0
beta-lactams	low	1	0
disulfanilamide	low	2	0
biotin	low	1	0
deflazacort	medium	3	1
cortisone	low	38	0
3-nitrotyrosine	low	1	0
sorbinil	low	1	0
trimethoprim, sulfamethoxazole drug combination	medium	2	1
bortezomib	low	1	0
fibrin	low	5	0
elastin	low	10	0
inositol 3-phosphate	low	3	0
cortodoxone	low	1	0
mycophenolic acid	low	1	0
y 27632	low	1	0
imidazolidines	low	1	0
melphalan	low	1	0
bromochloroacetic acid	low	2	0
ranitidine	low	1	0
lithium	low	1	0
2-fluoro-2-deoxyglucose-6-phosphate	low	2	0
nitinol	low	2	0
cathepsin g	low	1	0
dinoprost	low	1	0
alprostadil	low	1	0
amphotericin b	low	3	0
clavulanic acid	low	1	0
8-epi-prostaglandin f2alpha	low	1	0
4-hydroxy-2-nonenal	low	1	0
codeine	low	1	0
phenylephrine hydrochloride	low	4	0
iloprost	low	1	0
n-(n-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester	low	1	0
enalapril	low	1	0
phosphorus	low	1	0
limaprost	low	1	0
gadolinium dtpa	low	3	0
ergoline	low	1	0
sq-23377	low	1	0
mocetinostat	low	8	0
tofacitinib	medium	2	1
idelalisib	low	1	0
technetium tc 99m exametazime	low	1	0
dextrothyroxine	low	1	0
indocyanine green	low	6	0
acid phosphatase	low	1	0
jaw	low	17	0
calcitonin	medium	1	1
cholecystokinin	low	1	0
endothelin-1	low	4	0
gdc-0973	low	2	0
ubiquinone	low	1	0
ro13-9904	low	1	0
sodium ethylxanthate	low	2	0
cardiovascular agents	low	5	0
incb-018424	low	1	0
piperidines	medium	4	1
interleukin-8	low	3	0
tuftsin	low	1	0
ascorbic acid	low	1	0
chlortetracycline	low	4	0
oxytetracycline, anhydrous	low	1	0
minocycline	low	1	0
salicylates	low	4	0
acenocoumarol	low	1	0
warfarin	low	5	0
phenprocoumon	low	1	0
calca protein, human	low	2	0
transforming growth factor beta	low	4	0
agar	low	1	0
lewis x antigen	low	2	0
vitamin b 12	low	1	0
cyclosporine	medium	3	1
technetium tc 99m medronate	low	2	0
thromboplastin	low	1	0
muramidase	low	2	0
exudates	low	1	0
acyclovir	low	4	0
folic acid	low	2	0
rifampin	low	2	0
valacyclovir	low	2	0
olanzapine	low	1	0
allopurinol	low	2	0
sildenafil citrate	low	1	0
eye	low	70	0
concanavalin a	low	2	0

Protein Targets (2,072)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	39	0	0	39
thioredoxin reductase	45	0	0	45
ATAD5 protein, partial	24	0	0	24
GLS protein	32	0	0	32
TDP1 protein	74	0	0	74
regulator of G-protein signaling 4	20	0	0	20
67.9K protein	19	0	0	19
Parkin	7	0	0	7
bromodomain adjacent to zinc finger domain 2B	18	0	0	18
IDH1	25	0	0	25
euchromatic histone-lysine N-methyltransferase 2	76	0	0	76
nuclear factor erythroid 2-related factor 2 isoform 2	27	0	0	28
huntingtin isoform 2	9	0	0	9
ras-related protein Rab-9A	8	0	0	8
serine/threonine-protein kinase mTOR isoform 1	13	0	0	13
urokinase-type plasminogen activator precursor	18	0	0	18
plasminogen precursor	18	0	0	18
urokinase plasminogen activator surface receptor precursor	18	0	0	18
survival motor neuron protein isoform d	28	0	0	28
D(1A) dopamine receptor	7	2	0	9
Ataxin-2	37	0	0	37
ATP-dependent phosphofructokinase	31	0	0	31
acetylcholinesterase	24	0	0	24
pregnane X receptor	11	0	0	11
SMAD family member 2	19	0	0	19
SMAD family member 3	19	0	0	19
GLI family zinc finger 3	55	0	0	55
Microtubule-associated protein tau	31	0	0	32
AR protein	91	0	0	91
progesterone receptor	45	0	0	45
glucocorticoid receptor [Homo sapiens]	63	0	0	63
retinoic acid nuclear receptor alpha variant 1	62	0	0	62
retinoid X nuclear receptor alpha	47	0	0	47
estrogen-related nuclear receptor alpha	70	0	0	70
farnesoid X nuclear receptor	38	0	0	38
pregnane X nuclear receptor	54	0	0	54
estrogen nuclear receptor alpha	93	0	0	93
G	35	0	0	35
vitamin D (1,25- dihydroxyvitamin D3) receptor	49	0	0	49
arylsulfatase A	16	0	0	16
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	40	0	0	40
activating transcription factor 6	22	0	0	22
nuclear receptor subfamily 1, group I, member 2	14	0	0	14
chromobox protein homolog 1	42	0	0	42
nuclear factor erythroid 2-related factor 2 isoform 1	58	0	0	58
geminin	60	0	0	60
histone acetyltransferase KAT2A isoform 1	25	0	0	25
lamin isoform A-delta10	63	0	0	63
Voltage-dependent calcium channel gamma-2 subunit	34	0	0	34
Interferon beta	46	0	0	46
HLA class I histocompatibility antigen, B alpha chain	35	0	0	35
Glucocorticoid receptor	0	18	2	25
Sex hormone-binding globulin	0	0	7	7
Glycine receptor subunit alpha-1	0	18	0	18
Corticosteroid-binding globulin	0	8	0	8
Adenosine receptor A3	0	14	1	15
Replicase polyprotein 1ab	0	6	5	11
Androgen receptor	0	23	0	23
Alpha-1B adrenergic receptor	0	26	4	30
Glutamate receptor 2	34	3	1	38
Glycine receptor subunit beta	0	18	0	18
Glycine receptor subunit alpha-2	0	18	0	18
Glycine receptor subunit alpha-3	0	18	0	18
Mitogen-activated protein kinase 3	0	1	6	7
Alpha-1A adrenergic receptor	0	26	4	30
Sodium-dependent dopamine transporter	0	19	0	19
TAR DNA-binding protein 43	20	0	0	20
Inositol hexakisphosphate kinase 1	35	0	0	35
cytochrome P450 2C9, partial	35	0	0	35
hypoxia-inducible factor 1 alpha subunit	20	0	0	20
RAR-related orphan receptor gamma	53	0	0	53
aldehyde dehydrogenase 1 family, member A1	46	0	0	46
peroxisome proliferator-activated receptor delta	38	0	0	38
v-jun sarcoma virus 17 oncogene homolog (avian)	33	0	0	33
Histone H2A.x	32	0	0	32
thyroid hormone receptor beta isoform a	23	0	0	23
heat shock protein beta-1	22	0	0	22
Chain A, Putative fructose-1,6-bisphosphate aldolase	14	0	0	14
Chain A, JmjC domain-containing histone demethylation protein 3A	11	0	0	11
phosphopantetheinyl transferase	30	0	0	30
pyruvate kinase PKM isoform a	1	0	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Guanine nucleotide-binding protein G	6	0	0	6
Tubulin--tyrosine ligase	0	2	0	2
vitamin D3 receptor isoform VDRA	29	0	0	29
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Luciferase	27	0	0	27
peroxisome proliferator activated receptor gamma	45	0	0	45
thyroid stimulating hormone receptor	26	0	0	26
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	6	0	0	6
muscleblind-like protein 1 isoform 1	15	0	0	15
Smad3	13	0	0	13
thyroid stimulating hormone receptor	29	0	0	29
nuclear receptor subfamily 1, group I, member 3	47	0	0	47
EWS/FLI fusion protein	47	0	0	47
aryl hydrocarbon receptor	28	0	0	28
thyroid hormone receptor beta isoform 2	55	0	0	55
peripheral myelin protein 22	33	0	0	33
cytochrome P450 3A4 isoform 1	34	0	0	34
Gamma-aminobutyric acid receptor subunit pi	34	8	3	45
ATP-binding cassette sub-family C member 3	0	60	0	60
Multidrug resistance-associated protein 4	0	61	0	65
Solute carrier family 22 member 6	0	10	0	11
Carbonic anhydrase 12	0	9	1	16
UDP-glucuronosyltransferase 1A9	0	2	0	6
Bile salt export pump	0	20	0	20
Bile salt export pump	0	80	0	80
Cytochrome P450 2B1	0	1	0	2
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	21	1	32
Carbonic anhydrase 2	0	22	2	35
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	10	1	15
Prostaglandin G/H synthase 1	0	9	0	10
Carbonic anhydrase 3	0	6	1	13
Cytochrome P450 3A4	0	23	0	27
Cytochrome P450 2D6	0	20	1	22
Cytochrome P450 2C9	0	25	1	27
Polyunsaturated fatty acid lipoxygenase ALOX15	0	10	0	10
Gamma-aminobutyric acid receptor subunit beta-1	34	8	3	45
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	34	8	3	45
Gamma-aminobutyric acid receptor subunit gamma-2	34	8	4	46
UDP-glucuronosyltransferase 1-6	0	3	0	4
Gamma-aminobutyric acid receptor subunit alpha-5	34	8	3	45
Gamma-aminobutyric acid receptor subunit alpha-3	34	8	3	45
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	5	0	9
Carbonic anhydrase 4	0	9	1	15
Prostaglandin G/H synthase 1	0	13	0	14
Carbonic anhydrase 6	0	7	1	13
Gamma-aminobutyric acid receptor subunit gamma-1	34	8	3	45
Gamma-aminobutyric acid receptor subunit alpha-2	34	8	3	45
Gamma-aminobutyric acid receptor subunit alpha-4	34	8	3	45
Gamma-aminobutyric acid receptor subunit gamma-3	34	8	3	45
Gamma-aminobutyric acid receptor subunit alpha-6	34	8	3	45
Carbonic anhydrase 5A, mitochondrial	0	8	1	15
Prostaglandin G/H synthase 2	0	15	4	21
Carbonic anhydrase 7	0	6	1	12
Nuclear receptor ROR-gamma	16	0	0	16
Cytochrome P450 2J2	0	16	0	16
Gamma-aminobutyric acid receptor subunit alpha-1	34	10	4	48
Gamma-aminobutyric acid receptor subunit beta-3	34	8	3	45
Gamma-aminobutyric acid receptor subunit beta-2	34	8	4	46
Carbonic anhydrase 9	0	13	1	21
GABA theta subunit	34	8	3	45
Canalicular multispecific organic anion transporter 1	0	59	0	60
Carbonic anhydrase 15	0	6	0	10
Carbonic anhydrase 13	0	4	0	8
Gamma-aminobutyric acid receptor subunit epsilon	34	8	3	45
Carbonic anhydrase 14	0	7	1	14
Carbonic anhydrase 5B, mitochondrial	0	6	1	13
toxin B	0	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	27	0	0	27
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	22	0	0	22
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	2	0	2
GALC protein	5	0	0	5
cytochrome P450 family 3 subfamily A polypeptide 4	50	0	0	50
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Bloom syndrome protein isoform 1	24	0	0	24
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	3	0	3
Carbonic anhydrase 2	0	2	0	2
Cathepsin B	0	1	0	1
Steryl-sulfatase	0	1	0	2
5-hydroxytryptamine receptor 2C	0	11	0	12
Polyunsaturated fatty acid 5-lipoxygenase	0	4	0	4
Cytochrome P450 2C8	0	7	0	8
Cytochrome P450 2A6	0	4	1	5
5-hydroxytryptamine receptor 2A	0	13	0	14
Translocator protein	0	4	2	7
Cannabinoid receptor 1	0	1	0	1
Cytochrome P450 2B6	0	6	2	8
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	6	0	9
Serum paraoxonase/arylesterase 1	0	4	0	4
Dipeptidyl peptidase 4	0	1	0	2
Endochitinase	0	1	0	1
Adenosine receptor A2a	0	4	0	7
5-hydroxytryptamine receptor 2B	0	9	0	9
Sodium-dependent serotonin transporter	0	6	1	7
Delta-type opioid receptor	0	3	0	3
Cytochrome P450 2C19	0	14	0	15
Delta-type opioid receptor	0	4	0	4
Mu-type opioid receptor	0	4	0	4
Carbonic anhydrase	0	3	0	6
Kappa-type opioid receptor	0	2	0	5
Carbonic anhydrase	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	2	0	6
D(2) dopamine receptor	0	12	1	14
Cholinesterase	0	3	0	3
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	4	1	5
Fatty-acid amide hydrolase 1	1	3	0	4
Beta-carbonic anhydrase 1	0	3	0	3
Carbonic anhydrase 2	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	8	1	13
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	2	0	6
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	2	0	7
Carbonic anhydrase	0	2	0	7
Carbonic anhydrase	0	2	0	2
Sigma intracellular receptor 2	0	6	0	6
Delta carbonic anhydrase	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	4	1	5
Renin	0	1	0	1
Carbonic anhydrase	0	2	0	6
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	4	1	7
Carbonic anhydrase 4	0	5	0	7
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	24	0	0	24
Chain B, HADH2 protein	24	0	0	24
Chain A, ATP-DEPENDENT DNA HELICASE Q1	9	0	0	9
Chain A, Ferritin light chain	14	0	0	14
Thymidine kinase	0	2	0	3
hemoglobin subunit beta	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	6	0	0	6
ubiquitin carboxyl-terminal hydrolase 2 isoform a	10	0	0	10
Solute carrier family 22 member 1	0	14	0	21
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	2	0	6
POU domain, class 2, transcription factor 2	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	7	0	0	7
Purine nucleoside phosphorylase	0	0	3	3
Solute carrier family 22 member 6	0	6	0	9
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	5	0	9
Thymidine kinase	0	1	0	2
Chain A, farnesyl pyrophosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	4	0	5
Farnesyl pyrophosphate synthase	0	6	0	6
Acetylcholinesterase	0	9	2	11
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Farnesyl pyrophosphate synthase	0	3	0	3
Farnesyl pyrophosphate synthase	0	2	0	2
interleukin 8	10	0	0	10
estrogen receptor 2 (ER beta)	31	0	0	31
transcriptional regulator ERG isoform 3	5	0	0	5
Polyphenol oxidase 2	0	5	0	8
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Cellular tumor antigen p53	47	0	0	47
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	7	2	9
Xanthine dehydrogenase/oxidase	0	3	0	3
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	1	5
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	2	0	4
Thromboxane-A synthase	0	5	0	5
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostacyclin receptor	0	4	2	6
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Solute carrier organic anion transporter family member 2A1	0	1	0	4
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Fumarate hydratase	21	0	0	21
USP1 protein, partial	33	0	0	33
NFKB1 protein, partial	13	0	0	13
PPM1D protein	15	0	0	15
Thrombopoietin	12	0	0	12
caspase 7, apoptosis-related cysteine protease	16	0	0	16
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	21	0	0	21
cytochrome P450 2D6	28	0	0	28
polyprotein	21	0	0	21
caspase-3	16	0	0	16
cytochrome P450 2D6 isoform 1	17	0	0	17
cellular tumor antigen p53 isoform a	13	0	0	13
cytochrome P450 2C9 precursor	14	0	0	14
D(1A) dopamine receptor	15	0	0	15
potassium voltage-gated channel subfamily H member 2 isoform d	16	0	0	16
mitogen-activated protein kinase 1	17	0	0	17
flap endonuclease 1	12	0	0	12
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	16	0	0	16
nuclear receptor ROR-gamma isoform 1	20	0	0	20
muscarinic acetylcholine receptor M1	21	0	0	21
lethal factor (plasmid)	11	0	0	11
Polyunsaturated fatty acid lipoxygenase ALOX15B	12	0	0	12
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Solute carrier organic anion transporter family member 1A4	0	2	0	4
Voltage-dependent L-type calcium channel subunit alpha-1F	0	12	1	13
5-hydroxytryptamine receptor 4	0	24	0	24
Lysine-specific demethylase PHF2	0	1	0	1
Thyroid hormone receptor alpha	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	3	2	5
Integrin beta-3	11	1	1	13
Tyrosine-protein kinase Fyn	0	5	6	11
ATP-dependent translocase ABCB1	0	5	0	5
Aldo-keto reductase family 1 member B1	0	20	0	20
Muscarinic acetylcholine receptor M2	0	19	2	22
Muscarinic acetylcholine receptor M4	0	15	0	16
ATP-dependent translocase ABCB1	0	17	2	24
Integrin alpha-IIb	11	1	1	13
Beta-1 adrenergic receptor	0	8	1	9
Muscarinic acetylcholine receptor M5	0	17	0	18
Alpha-2A adrenergic receptor	0	30	3	34
Thyroid hormone receptor alpha	0	1	1	2
Thyroid hormone receptor beta	0	1	1	2
Muscarinic acetylcholine receptor M1	0	17	4	22
Beta-3 adrenergic receptor	0	6	1	7
D(2) dopamine receptor	0	28	3	34
Lethal factor	0	1	0	1
Alpha-2B adrenergic receptor	0	30	2	33
Thyroid hormone receptor beta	0	1	0	1
Muscarinic acetylcholine receptor M3	0	16	1	18
ATP-dependent translocase ABCB1	0	5	0	5
Substance-K receptor	0	6	0	6
D(1A) dopamine receptor	0	25	1	28
D(4) dopamine receptor	0	8	1	12
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Sodium-dependent noradrenaline transporter	0	23	1	24
Histamine H2 receptor	0	13	2	15
Endothelin-1 receptor	0	4	1	5
5-hydroxytryptamine receptor 2A	0	28	2	30
5-hydroxytryptamine receptor 2C	0	26	2	28
Lysine-specific demethylase 5A	0	1	0	1
B2 bradykinin receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	25	0	25
Melanocortin receptor 4	0	4	0	4
C-8 sterol isomerase	0	4	0	4
Melanocortin receptor 5	0	4	0	4
Mu-type opioid receptor	0	13	3	16
D(3) dopamine receptor	0	22	1	26
Sodium channel protein type 1 subunit alpha	0	6	0	6
Sodium channel protein type 4 subunit alpha	0	8	0	9
Squalene synthase	0	1	0	1
Delta-type opioid receptor	0	7	1	8
Kappa-type opioid receptor	0	11	1	12
5-hydroxytryptamine receptor 2B	0	24	1	25
C-C chemokine receptor type 2	0	5	0	5
Melanocortin receptor 3	0	4	0	4
Histamine H2 receptor	21	2	1	26
5-hydroxytryptamine receptor 6	0	25	1	26
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
C-C chemokine receptor type 4	0	2	0	2
Spike glycoprotein	30	3	5	38
Sodium channel protein type 7 subunit alpha	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1D	0	12	1	13
Potassium voltage-gated channel subfamily H member 2	0	28	0	29
Voltage-dependent L-type calcium channel subunit alpha-1S	0	12	1	13
Voltage-dependent L-type calcium channel subunit alpha-1C	0	13	1	15
Sodium channel protein type 5 subunit alpha	0	8	0	8
Squalene monooxygenase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	4	0	4
Sodium channel protein type 9 subunit alpha	0	9	0	9
Lysine-specific demethylase 7A	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	6	0	6
Sigma non-opioid intracellular receptor 1	0	20	1	21
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Sodium channel protein type 3 subunit alpha	0	7	0	7
Sodium channel protein type 11 subunit alpha	0	6	0	6
Histone lysine demethylase PHF8	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	6	0	6
Sodium channel protein type 10 subunit alpha	0	6	0	6
atrial natriuretic peptide receptor 2 precursor	5	0	0	5
Albumin	0	0	6	6
High affinity nerve growth factor receptor	0	1	7	8
Muscarinic acetylcholine receptor M1	0	6	0	7
Muscarinic acetylcholine receptor M3	0	6	0	7
Muscarinic acetylcholine receptor M4	0	6	0	7
Muscarinic acetylcholine receptor M5	0	7	0	8
Muscarinic acetylcholine receptor M2	0	6	0	7
Angiotensin-converting enzyme	0	9	0	10
Alpha-2C adrenergic receptor	0	25	2	28
5-hydroxytryptamine receptor 1A	0	30	4	35
D(1B) dopamine receptor	0	4	0	6
UDP-glucuronosyltransferase 1A4	0	2	0	7
Alpha-1D adrenergic receptor	0	22	2	25
5-hydroxytryptamine receptor 1B	0	22	0	22
5-hydroxytryptamine receptor 1D	0	4	1	5
5-hydroxytryptamine receptor 1F	0	3	0	3
5-hydroxytryptamine receptor 6	0	2	0	2
Histamine H1 receptor	0	6	1	7
5-hydroxytryptamine receptor 7	0	4	0	4
5-hydroxytryptamine receptor 5A	0	2	0	2
5-hydroxytryptamine receptor 5B	0	2	0	2
Histamine H1 receptor	0	14	3	17
UDP-glucuronosyltransferase 1A3	0	0	0	3
5-hydroxytryptamine receptor 3A	0	3	0	3
5-hydroxytryptamine receptor 7	0	7	0	7
Voltage-dependent N-type calcium channel subunit alpha-1B	0	3	0	3
5-hydroxytryptamine receptor 4	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	5	0	5
5-hydroxytryptamine receptor 3B	0	3	0	3
Histamine H3 receptor	0	4	2	6
Chain A, 2-oxoglutarate Oxygenase	25	0	0	25
Beta-lactamase	0	1	0	3
Beta-lactamase	0	1	0	4
Beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	4
apical membrane antigen 1, AMA1	10	0	0	10
Beta-lactamase	0	0	0	3
DNA polymerase eta isoform 1	7	0	0	7
DNA polymerase iota isoform a (long)	26	0	0	26
DNA polymerase kappa isoform 1	19	0	0	19
Beta-lactamase SHV-1	0	1	0	4
Beta-lactamase SHV-1	0	2	0	5
Beta-lactamase	0	1	0	4
Solute carrier family 15 member 1	0	9	0	10
Solute carrier family 15 member 1	0	5	0	5
B2 metallo-beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	4	0	4
Beta-lactamase	0	1	0	4
Beta-lactamase	0	1	0	4
Solute carrier family 15 member 2	0	5	0	5
Beta-lactamase	0	1	0	4
Beta-lactamase	0	0	0	3
Chain A, Cruzipain	9	0	0	9
tumor necrosis factor	3	0	0	3
Aurora kinase B	0	1	6	7
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	6	0	7
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Beta-lactamase	0	0	0	3
acid sphingomyelinase	5	0	0	5
Beta-lactamase	0	2	0	4
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase type 2	0	1	1	5
Metallo-beta-lactamase VIM-11	0	0	0	3
Metallo-beta-lactamase VIM-2	0	0	0	3
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	2	0	4
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	19	0	0	19
DNA polymerase beta	6	0	0	6
60 kDa heat shock protein, mitochondrial	0	4	0	4
Beta-lactamase OXA-7	0	0	0	1
10 kDa heat shock protein, mitochondrial	0	4	0	4
Angiopoietin-1 receptor	0	0	3	3
Beta-lactamase	0	1	0	3
Beta-lactamase	0	1	0	3
Beta-lactamase	0	1	0	3
Thiosulfate sulfurtransferase	0	4	0	4
Metallo-beta-lactamase VIM-13	0	0	0	3
Efflux transporter	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase Toho-1	0	0	0	3
Beta-lactamase	0	0	0	2
Class D beta-lactamase	0	1	0	3
60 kDa chaperonin	0	4	0	4
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	2
10 kDa chaperonin	0	4	0	4
Metallo-b-lactamase	0	0	0	4
Carbapenem-hydrolyzing beta-lactamase KPC	0	2	0	5
Beta-lactamase class B VIM-2	0	1	1	6
Beta-lactamase VIM-1	0	0	0	3
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	16	0	0	16
lethal(3)malignant brain tumor-like protein 1 isoform I	3	0	0	3
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
cytochrome P450 2C19 precursor	9	0	0	9
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	4	1	8
Glutamate receptor ionotropic, NMDA 1	0	6	1	11
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	6	1	11
Glutamate receptor ionotropic, NMDA 2C	0	6	1	11
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Carbonic anhydrase-like protein, putative	0	0	0	5
Glutamate receptor ionotropic, NMDA 2D	0	6	1	11
Glutamate receptor ionotropic, NMDA 3B	0	6	1	11
Glutamate receptor ionotropic, NMDA 3A	0	6	1	11
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	2	2
ras protein, partial	0	0	2	2
hypothetical protein, conserved	6	0	0	6
glucocerebrosidase	10	0	0	10
Rac1 protein	0	0	2	2
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	2	2
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 1	0	5	0	6
Prostaglandin G/H synthase 2	0	4	0	5
Epidermal growth factor receptor	0	6	6	12
Fatty acid-binding protein, liver	0	4	0	4
Myeloperoxidase	0	5	0	5
Seed linoleate 13S-lipoxygenase-1	0	2	0	2
Glutathione hydrolase 1 proenzyme	0	1	0	1
Substance-P receptor	0	2	0	2
Urotensin-2 receptor	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	2	2
Prostaglandin G/H synthase 2	0	7	0	7
Rho-associated protein kinase 2	0	4	0	4
Nicotinate phosphoribosyltransferase	0	6	0	6
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	3	1	4
Caspase-7	9	0	0	9
caspase-3	9	0	0	9
Solute carrier organic anion transporter family member 2B1	0	6	0	7
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Histone deacetylase 1	0	5	0	5
Histone deacetylase 2	0	5	0	5
Solute carrier organic anion transporter family member 1B3	0	10	0	14
Histone deacetylase 6	0	5	0	5
Solute carrier organic anion transporter family member 1B1	0	7	0	11
P53	2	0	0	2
peripheral myelin protein 22 isoform 1	15	0	0	15
M-phase phosphoprotein 8	12	0	0	12
ATPase family AAA domain-containing protein 5	26	0	0	26
Protein-arginine deiminase type-4	0	9	0	9
Gamma-aminobutyric acid type B receptor subunit 2	0	2	1	3
Gamma-aminobutyric acid type B receptor subunit 2	0	2	0	2
Gamma-aminobutyric acid type B receptor subunit 1	0	2	1	3
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Bone morphogenetic protein receptor type-1B	0	0	6	6
Membrane-associated progesterone receptor component 1	0	0	4	4
Serine/threonine-protein kinase PLK4	0	0	6	6
ATP-dependent RNA helicase DDX3X	0	0	6	6
Pyridoxal kinase	0	0	6	7
Citron Rho-interacting kinase	0	0	6	6
Serine/threonine-protein kinase Chk1	0	1	6	7
Aurora kinase A	0	0	6	6
Cyclin-G-associated kinase	0	2	6	8
Ephrin type-B receptor 6	0	0	6	6
Peroxisomal acyl-coenzyme A oxidase 3	0	0	6	6
Receptor-interacting serine/threonine-protein kinase 2	0	0	6	6
Dynamin-like 120 kDa protein, mitochondrial	0	0	6	6
Tyrosine-protein kinase JAK2	0	6	4	13
Eukaryotic translation initiation factor 5B	0	0	5	5
Rho-associated protein kinase 2	0	5	6	11
Serine/threonine-protein kinase ULK1	0	0	6	6
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	6	6
Ribosomal protein S6 kinase alpha-5	0	3	6	9
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	6	6
Ribosomal protein S6 kinase alpha-4	0	0	6	6
Serine/threonine-protein kinase 16	0	0	6	6
Serine/threonine-protein kinase 10	0	0	6	6
Serine/threonine-protein kinase D3	0	0	7	7
Structural maintenance of chromosomes protein 2	0	0	5	5
Mitogen-activated protein kinase kinase kinase 6	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	6	6
Serine/threonine-protein kinase LATS1	0	0	6	6
Serine/threonine-protein kinase PAK 4	0	0	6	6
Tyrosine-protein kinase ABL1	0	1	8	9
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	4	4
ADP/ATP translocase 2	0	0	6	6
Protein kinase C beta type	0	1	7	8
Insulin receptor	0	1	6	7
Tyrosine-protein kinase Lck	0	3	6	9
Cyclin-dependent kinase 1	0	0	6	6
Glycogen phosphorylase, liver form	0	0	6	6
Tyrosine-protein kinase Fes/Fps	0	0	6	6
Adenine phosphoribosyltransferase	0	0	3	3
Tyrosine-protein kinase Yes	0	0	6	6
Tyrosine-protein kinase Lyn	0	0	6	6
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	6	6
Insulin-like growth factor 1 receptor	0	0	6	6
Signal recognition particle receptor subunit alpha	0	0	5	5
Cytochrome c1, heme protein, mitochondrial	0	0	6	6
Hepatocyte growth factor receptor	0	0	6	6
Tyrosine-protein kinase HCK	0	0	6	6
Platelet-derived growth factor receptor beta	0	0	6	6
Serine/threonine-protein kinase A-Raf	0	0	6	6
Glycogen phosphorylase, brain form	0	0	6	6
Breakpoint cluster region protein	0	0	7	7
Serine/threonine-protein kinase pim-1	0	0	6	6
Fibroblast growth factor receptor 1	0	0	6	6
DNA topoisomerase 2-alpha	0	2	6	16
Cyclin-dependent kinase 4	0	0	6	6
ADP/ATP translocase 3	0	0	6	6
Inosine-5'-monophosphate dehydrogenase 2	0	2	5	7
Proto-oncogene tyrosine-protein kinase Src	0	0	6	6
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	5	5
Serine/threonine-protein kinase B-raf	0	1	6	7
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	6	6
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	6	7
Tyrosine-protein kinase Fer	0	0	6	6
Protein kinase C alpha type	0	2	7	9
cAMP-dependent protein kinase catalytic subunit alpha	0	3	6	9
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	6	6
Casein kinase II subunit alpha'	0	0	6	6
Ras-related protein Rab-6A	0	0	5	5
Ephrin type-A receptor 1	0	0	6	6
Multifunctional protein ADE2	0	0	6	6
cAMP-dependent protein kinase catalytic subunit gamma	0	3	6	9
cAMP-dependent protein kinase catalytic subunit beta	0	3	6	9
Ferrochelatase, mitochondrial	0	0	6	6
Ribosomal protein S6 kinase beta-1	0	1	5	6
Tyrosine-protein kinase JAK1	0	6	8	17
Cyclin-dependent kinase 2	0	1	7	8
Beta-adrenergic receptor kinase 1	0	0	6	6
Probable ATP-dependent RNA helicase DDX6	0	0	6	6
MAP/microtubule affinity-regulating kinase 3	0	0	6	6
Deoxycytidine kinase	0	0	6	7
Mitogen-activated protein kinase 1	0	1	6	7
Ephrin type-A receptor 2	0	0	6	6
Ephrin type-B receptor 2	0	0	6	6
Non-receptor tyrosine-protein kinase TYK2	0	6	8	17
UMP-CMP kinase	0	0	2	2
Phosphatidylethanolamine-binding protein 1	0	0	5	5
Wee1-like protein kinase	0	0	6	6
Heme oxygenase 2	0	0	6	6
S-adenosylmethionine synthase isoform type-2	0	0	6	6
DnaJ homolog subfamily A member 1	0	0	6	6
RAC-alpha serine/threonine-protein kinase	0	1	6	7
RAC-beta serine/threonine-protein kinase	0	0	6	6
DNA replication licensing factor MCM4	0	0	5	5
Myosin-10	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 2	0	1	6	7
Receptor-type tyrosine-protein kinase FLT3	0	0	6	6
Bone morphogenetic protein receptor type-1A	0	0	6	6
Activin receptor type-1B	0	0	6	6
TGF-beta receptor type-1	0	0	6	6
Serine/threonine-protein kinase receptor R3	0	0	3	3
TGF-beta receptor type-2	0	0	6	6
Electron transfer flavoprotein subunit beta	0	0	5	5
Tyrosine-protein kinase CSK	0	1	6	7
Glycine--tRNA ligase	0	0	6	6
Protein kinase C iota type	0	0	7	7
Exosome RNA helicase MTR4	0	0	6	6
Tyrosine-protein kinase Tec	0	1	6	7
Tyrosine-protein kinase ABL2	0	0	6	6
Tyrosine-protein kinase FRK	0	0	6	6
G protein-coupled receptor kinase 6	0	0	3	3
Tyrosine-protein kinase SYK	0	0	6	6
26S proteasome regulatory subunit 6B	0	1	6	7
Mitogen-activated protein kinase 8	0	1	6	7
Mitogen-activated protein kinase 9	0	0	6	6
Dual specificity mitogen-activated protein kinase kinase 3	0	0	6	6
Casein kinase I isoform alpha	0	0	6	6
Casein kinase I isoform delta	0	0	6	6
MAP kinase-activated protein kinase 2	0	1	6	7
Elongation factor Tu, mitochondrial	0	0	6	6
Cysteine--tRNA ligase, cytoplasmic	0	0	6	6
Casein kinase I isoform epsilon	0	0	6	6
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	6	6
Dual specificity protein kinase CLK1	0	0	6	6
Dual specificity protein kinase CLK2	0	0	6	6
Dual specificity protein kinase CLK3	0	0	4	4
Glycogen synthase kinase-3 alpha	0	0	6	6
Glycogen synthase kinase-3 beta	0	2	6	8
Cyclin-dependent kinase 7	0	0	6	6
Cyclin-dependent kinase 9	0	0	6	6
Ras-related protein Rab-27A	0	0	5	5
Interleukin-1 receptor-associated kinase 1	0	0	6	6
Ribosomal protein S6 kinase alpha-3	0	1	6	7
Serine/threonine-protein kinase Nek2	0	0	6	6
Serine/threonine-protein kinase Nek3	0	0	6	6
Tyrosine-protein kinase JAK3	0	6	3	13
Dual specificity mitogen-activated protein kinase kinase 6	0	0	6	6
LIM domain kinase 1	0	0	6	6
LIM domain kinase 2	0	0	6	6
Mitogen-activated protein kinase 10	0	0	6	6
Tyrosine--tRNA ligase, cytoplasmic	0	0	6	6
5'-AMP-activated protein kinase subunit gamma-1	0	0	6	7
Ephrin type-B receptor 3	0	0	6	6
Ephrin type-A receptor 5	0	0	6	6
Ephrin type-B receptor 4	0	0	6	6
Ephrin type-A receptor 4	0	0	6	6
Adenylate kinase 2, mitochondrial	0	0	6	6
Adenosine kinase	0	0	5	5
Ras-related protein Rab-10	0	0	6	6
Actin-related protein 3	0	1	6	7
Actin-related protein 2	0	0	4	4
GTP-binding nuclear protein Ran	0	0	6	6
Casein kinase I isoform gamma-2	0	0	6	6
Cyclin-dependent kinase 3	0	0	5	5
Cyclin-dependent kinase 6	0	0	6	6
Cyclin-dependent-like kinase 5	0	1	6	7
Cyclin-dependent kinase 16	0	0	6	6
Cyclin-dependent kinase 17	0	0	6	6
ATP-dependent 6-phosphofructokinase, platelet type	0	0	6	6
Dual specificity mitogen-activated protein kinase kinase 1	0	1	6	7
DNA topoisomerase 2-beta	0	1	7	14
Protein kinase C theta type	0	0	7	7
Activin receptor type-1	0	0	6	6
Macrophage-stimulating protein receptor	0	0	6	6
Focal adhesion kinase 1	0	0	6	6
Protein kinase C delta type	0	1	7	8
Tyrosine-protein kinase BTK	0	1	6	7
Activated CDC42 kinase 1	0	0	6	6
Epithelial discoidin domain-containing receptor 1	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	6	6
Serine/threonine-protein kinase 4	0	0	6	6
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	6	7
Dual specificity mitogen-activated protein kinase kinase 5	0	0	6	6
Mitogen-activated protein kinase 7	0	0	6	6
Serine/threonine-protein kinase PAK 2	0	0	6	6
Serine/threonine-protein kinase 3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 1	0	0	6	6
Integrin-linked protein kinase	0	0	6	6
Rho-associated protein kinase 1	0	4	6	10
Non-receptor tyrosine-protein kinase TNK1	0	0	6	6
Serine/threonine-protein kinase ATR	0	0	4	4
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	6	6
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	6	6
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	6	6
Activin receptor type-2B	0	0	6	6
Bone morphogenetic protein receptor type-2	0	0	6	6
Protein-tyrosine kinase 6	0	0	6	6
cGMP-dependent protein kinase 1	0	0	6	6
Cyclin-dependent kinase 13	0	0	6	6
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	6	6
Protein-tyrosine kinase 2-beta	0	0	6	6
Maternal embryonic leucine zipper kinase	0	0	6	6
Structural maintenance of chromosomes protein 1A	0	0	5	5
Chromodomain-helicase-DNA-binding protein 4	0	0	6	6
Peroxisomal acyl-coenzyme A oxidase 1	0	0	5	5
Ephrin type-A receptor 7	0	0	6	6
Delta(24)-sterol reductase	0	0	5	5
Ribosomal protein S6 kinase alpha-1	0	0	6	6
Dual specificity testis-specific protein kinase 1	0	0	6	6
Myosin light chain kinase, smooth muscle	0	3	6	9
Mitogen-activated protein kinase 11	0	1	6	7
Serine/threonine-protein kinase STK11	0	0	6	6
Serine/threonine-protein kinase N1	0	1	6	7
Serine/threonine-protein kinase N2	0	2	6	8
Mitogen-activated protein kinase 14	0	2	6	8
Calcium/calmodulin-dependent protein kinase type IV	0	0	6	6
Mitogen-activated protein kinase kinase kinase 11	0	0	6	6
MAP kinase-activated protein kinase 3	0	0	3	3
Discoidin domain-containing receptor 2	0	0	6	6
AP2-associated protein kinase 1	0	2	6	8
Myosin light chain kinase 3	0	0	6	6
Uncharacterized aarF domain-containing protein kinase 5	0	0	4	4
Putative heat shock protein HSP 90-beta 2	0	0	6	6
Rab-like protein 3	0	0	4	4
Serine/threonine-protein kinase MRCK alpha	0	0	6	6
Serine/threonine-protein kinase MRCK gamma	0	0	5	5
Acyl-CoA dehydrogenase family member 10	0	0	6	6
Serine/threonine-protein kinase ULK3	0	0	6	6
Uncharacterized protein FLJ45252	0	0	6	6
Acyl-CoA dehydrogenase family member 11	0	0	5	5
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	6	6
Serine/threonine-protein kinase MARK2	0	0	6	6
ATP-dependent RNA helicase DHX30	0	0	5	5
Serine/threonine-protein kinase TAO1	0	0	6	6
STE20-related kinase adapter protein alpha	0	0	6	6
Myosin-14	0	0	5	5
AarF domain-containing protein kinase 1	0	0	6	6
ATP-dependent RNA helicase DDX42	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	6	6
MAP kinase-activated protein kinase 5	0	1	6	7
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	3	3
Misshapen-like kinase 1	0	0	5	5
Atypical kinase COQ8A, mitochondrial	0	0	6	6
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	6	6
Mitogen-activated protein kinase 15	0	0	6	6
Serine/threonine-protein kinase Nek9	0	0	6	6
ATP-dependent RNA helicase DDX1	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	6	6
Calcium/calmodulin-dependent protein kinase type 1G	0	0	3	3
Serine/threonine-protein kinase Nek1	0	0	6	6
PAS domain-containing serine/threonine-protein kinase	0	0	5	5
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	6	6
EKC/KEOPS complex subunit TP53RK	0	0	6	6
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	6	6
Mitogen-activated protein kinase kinase kinase 5	0	0	6	6
Mitogen-activated protein kinase kinase kinase 3	0	0	6	6
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	6	6
Nucleolar GTP-binding protein 1	0	0	6	6
Serine/threonine-protein kinase D2	0	0	6	6
NUAK family SNF1-like kinase 2	0	0	5	5
RNA cytidine acetyltransferase	0	0	6	6
Serine/threonine-protein kinase SIK2	0	0	6	6
STE20-like serine/threonine-protein kinase	0	0	6	6
Serine/threonine-protein kinase TAO3	0	0	6	6
dCTP pyrophosphatase 1	0	0	6	6
Dual specificity protein kinase CLK4	0	0	6	6
Casein kinase I isoform gamma-1	0	0	6	6
Serine/threonine-protein kinase PAK 6	0	0	5	5
Phenylalanine--tRNA ligase beta subunit	0	0	6	6
Isoleucine--tRNA ligase, mitochondrial	0	0	2	2
BMP-2-inducible protein kinase	0	0	6	6
Obg-like ATPase 1	0	0	2	2
Midasin	0	0	6	6
Interleukin-1 receptor-associated kinase 4	0	0	6	6
Mitogen-activated protein kinase kinase kinase 20	0	0	6	6
Cyclin-dependent kinase 12	0	0	6	6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	6	6
Serine/threonine-protein kinase 26	0	0	6	6
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	6	6
Serine/threonine-protein kinase NLK	0	0	6	6
5'-AMP-activated protein kinase subunit gamma-2	0	0	6	7
Serine/threonine-protein kinase TBK1	0	1	6	7
Septin-9	0	0	6	6
Ribosomal protein S6 kinase alpha-6	0	0	6	6
TRAF2 and NCK-interacting protein kinase	0	0	6	6
Serine/threonine-protein kinase TAO2	0	0	6	6
Long-chain-fatty-acid--CoA ligase 5	0	0	5	5
Serine/threonine-protein kinase ICK	0	0	5	5
RAC-gamma serine/threonine-protein kinase	0	0	6	6
Serine/threonine-protein kinase 38-like	0	0	5	5
Serine/threonine-protein kinase SIK3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 2	0	0	6	6
Thyroid hormone receptor-associated protein 3	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	6	6
Receptor-interacting serine/threonine-protein kinase 3	0	0	6	6
Serine/threonine-protein kinase MRCK beta	0	0	6	6
Interleukin-1 receptor-associated kinase 3	0	0	6	6
Serine/threonine-protein kinase 24	0	0	5	5
Casein kinase I isoform gamma-3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 4	0	0	6	6
galanin receptor type 3	0	1	0	1
ORF73	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	2
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	2
Histone deacetylase 3	0	4	0	4
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Prothrombin	0	2	1	4
Chymotrypsinogen A	0	2	0	3
Cathepsin B	0	1	0	1
Neutrophil elastase	0	2	0	2
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Proteasome subunit beta type-1	0	1	0	3
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	2
Proteasome subunit alpha type-2	0	1	0	2
Proteasome subunit alpha type-3	0	1	0	2
Proteasome subunit alpha type-4	0	1	0	2
Proteasome subunit beta type-8	0	1	0	2
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	2
Proteasome subunit alpha type-5	0	1	0	2
Proteasome subunit beta type-4	0	1	0	2
Proteasome subunit beta type-6	0	1	0	2
Proteasome subunit beta type-5	0	2	0	4
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	2
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	2
Proteasome subunit beta type-2	0	1	0	3
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	1	3
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Proteasome subunit alpha-type 8	0	1	0	2
Proteasome subunit beta type-7	0	1	0	2
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Histone deacetylase 8	0	3	0	3
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Genome polyprotein	0	3	2	5
dopamine D1 receptor	7	0	0	7
5-hydroxytryptamine receptor 1A	0	10	2	12
D	0	8	0	8
D(3) dopamine receptor	0	9	0	9
Alpha-2B adrenergic receptor	0	11	4	15
Alpha-2C adrenergic receptor	0	11	4	15
Alpha-2A adrenergic receptor	0	11	4	15
D(1B) dopamine receptor	0	7	0	7
D(4) dopamine receptor	0	8	0	8
Alpha-synuclein	3	2	0	5
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
15-lipoxygenase, partial	9	0	0	9
transient receptor potential cation channel subfamily V member 1	2	0	0	2
Neprilysin	0	1	0	1
Neprilysin	0	1	0	1
Leukotriene A-4 hydrolase	0	4	1	5
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	3	1	4
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	2
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	3	0	3
Angiotensin-converting enzyme	0	3	0	3
Beta-lactamase TEM	0	4	0	6
Beta-lactamase	0	2	0	3
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	5	5	10
Vpr	3	0	0	3
Major prion protein	0	0	6	6
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	3	0	7
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
Beta-lactamase	0	1	0	3
Beta-lactamase	0	1	0	3
Metallo-beta-lactamase VIM-19	0	0	0	2
Beta-lactamase	0	1	0	3
Albumin	0	4	10	15
Beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	3
Metallo-beta-lactamase VIM-2	0	0	0	2
Solute carrier family 22 member 7	0	1	0	4
BlaVIM-1	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	3
Solute carrier family 22 member 11	0	1	0	4
Solute carrier family 22 member 8	0	2	0	3
Solute carrier family 22 member 7	0	1	0	2
Chain A, Carbonic anhydrase II	0	1	0	1
glp-1 receptor, partial	18	0	0	18
thyrotropin-releasing hormone receptor	6	0	0	6
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	21	0	0	21
interferon gamma precursor	0	0	0	1
prostaglandin E2 receptor EP2 subtype	0	0	0	2
Prostaglandin E synthase	0	2	0	2
3-phosphoinositide-dependent protein kinase 1	0	1	2	3
cGMP-specific 3',5'-cyclic phosphodiesterase	0	5	0	5
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	3	0	3
Procathepsin L	0	6	5	11
Neuronal acetylcholine receptor subunit alpha-4	6	3	0	9
Quinolone resistance protein NorA	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	6	3	0	9
Calpain-2 catalytic subunit	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Cruzipain	0	1	0	1
Sodium/hydrogen exchanger 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	3	0	3
Bifunctional epoxide hydrolase 2	0	2	0	2
Prostaglandin G/H synthase 2	0	4	0	4
Histone deacetylase 4	0	2	0	2
Prostaglandin G/H synthase 2	0	3	0	4
Prostaglandin G/H synthase 1	0	4	0	4
Prostaglandin G/H synthase 1	0	1	0	1
Cyclooxygenase-2	0	2	0	2
Histone deacetylase 7	0	2	0	2
Rap guanine nucleotide exchange factor 4	4	0	0	4
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	2	0	2
P2Y purinoceptor 12	0	3	0	3
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	2	0	2
FAD-linked sulfhydryl oxidase ALR	0	0	0	2
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	3	0	3
Spike glycoprotein	0	3	5	8
Replicase polyprotein 1ab	0	3	6	9
glucose-6-phosphate 1-dehydrogenase isoform b	0	3	0	3
Transmembrane protease serine 2	0	3	5	8
Dihydrofolate reductase	0	2	0	2
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Amyloid-beta precursor protein	0	5	0	5
Histidine-rich protein PFHRP-II	0	1	0	2
Replicase polyprotein 1a	0	3	5	8
Replicase polyprotein 1ab	0	3	5	8
Replicase polyprotein 1ab	0	5	5	10
Spike glycoprotein	0	1	0	1
DNA ligase 1	0	1	0	1
Serine/threonine-protein kinase mTOR	0	2	2	4
Beta-secretase 1	0	2	0	2
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	2	0	2
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	3	0	3
Phosphoethanolamine N-methyltransferase	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
NADPH oxidase 1	0	1	0	1
Snq2p	0	0	0	3
Adenylate cyclase type 1	0	3	0	3
histone deacetylase 9 isoform 3	5	0	0	5
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Potassium channel subfamily K member 2	0	3	1	4
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Major prion protein	0	0	1	1
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	3	1	4
Sphingomyelin phosphodiesterase	0	2	0	2
D(2) dopamine receptor	0	3	0	3
Adenylate cyclase type 3	0	3	0	3
Alpha-1D adrenergic receptor	0	13	4	17
Sodium-dependent dopamine transporter	0	6	0	6
Adenylate cyclase type 2	0	3	0	3
Adenylate cyclase type 4	0	3	0	3
Trypanothione reductase	0	4	0	4
Histamine H1 receptor	0	3	4	7
Pleiotropic ABC efflux transporter of multiple drugs	0	3	0	6
5-hydroxytryptamine receptor 7	0	6	1	7
Adenylate cyclase type 8	0	3	0	3
Gastrin/cholecystokinin type B receptor	0	2	0	2
Calmodulin	0	1	2	3
Aldehyde oxidase 1	0	1	0	1
Adenylate cyclase type 6	0	3	0	3
Adenylate cyclase type 5	0	3	0	3
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Aldehyde oxidase	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Adenylyl cyclase 7	0	3	0	3
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
D	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	3
P2Y purinoceptor 12	0	2	0	2
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	3	0	5
DNA gyrase subunit B	0	3	0	5
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	2	0	3
DNA gyrase subunit A	0	1	0	2
Multidrug resistance protein MdtK	0	0	2	2
DNA gyrase subunit B	0	3	0	3
DNA gyrase subunit A	0	3	0	3
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	6
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	2	0	2
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
tyrosine-protein kinase Yes	3	0	0	3
relaxin receptor 1 isoform 1	2	0	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
Adenosine receptor A3	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	2	0	2
Beta-lactamase	0	1	0	3
Beta-lactamase OXA-1	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Type IV secretion-like conjugative transfer relaxase protein TraI	0	2	0	2
72 kDa type IV collagenase	0	2	0	2
Stromelysin-1	0	2	2	4
Matrix metalloproteinase-9	0	3	0	3
Macrophage metalloelastase	0	1	0	1
nonstructural protein 1	11	0	0	11
Liver carboxylesterase 1	0	1	0	2
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	2	0	2
Cytochrome P450 2D3	0	2	0	2
Kappa-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Cytochrome P450 2D4	0	2	0	2
Mas-related G-protein coupled receptor member X2	0	0	2	2
B2 bradykinin receptor	0	1	0	1
Dihydrofolate reductase	0	5	0	7
Dihydrofolate reductase	0	2	0	2
Beta-galactosidase	0	1	0	2
Choline O-acetyltransferase	0	1	0	1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	2	0	2
PH domain leucine-rich repeat-containing protein phosphatase 2	0	1	0	1
Chymotrypsin-C	0	1	0	1
Solute carrier family 22 member 2	0	7	0	9
Solute carrier family 22 member 3	0	4	0	5
Solute carrier family 22 member 3	0	1	0	1
Mineralocorticoid receptor	0	2	2	4
Solute carrier organic anion transporter family member 1A1	0	2	0	4
Solute carrier family 22 member 1	0	7	0	9
Solute carrier family 22 member 2	0	7	0	8
endonuclease IV	7	0	0	7
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Multidrug and toxin extrusion protein 1	0	12	0	12
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	2	0	2
importin subunit beta-1 isoform 1	9	0	0	9
snurportin-1	9	0	0	9
GTP-binding nuclear protein Ran isoform 1	4	0	0	4
Rap guanine nucleotide exchange factor 3	8	0	0	8
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Beta-glucuronidase	0	1	0	1
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	6	0	6
G-protein coupled bile acid receptor 1	0	0	2	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Multidrug resistance-associated protein 1	0	1	0	3
Solute carrier organic anion transporter family member 1A2	0	1	0	3
Solute carrier organic anion transporter family member 1A3	0	2	0	5
ATP-binding cassette sub-family C member 11	0	0	0	2
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
neuropeptide S receptor isoform A	7	0	0	7
Gamma-aminobutyric acid	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Alpha-1-acid glycoprotein 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	3	1	4
Translocator protein	0	1	0	1
Translocator protein	0	3	1	5
Cholecystokinin receptor type A	0	4	0	4
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
Aldo-keto reductase family 1 member B10	0	3	0	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Transthyretin	0	1	1	5
Interleukin-8	0	2	0	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	0	1
Aldo-keto reductase family 1 member B1	0	7	0	7
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
UDP-glucuronosyltransferase 2B10	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
UDP-glucuronosyltransferase 1A7	0	1	0	2
UDP-glucuronosyltransferase 1A10	0	1	0	2
Alpha-1A adrenergic receptor	0	5	3	9
Alpha-1B adrenergic receptor	0	3	2	6
Multidrug and toxin extrusion protein 2	0	4	0	4
Thromboxane A2 receptor	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	1	2	3
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin F2-alpha receptor	0	2	0	2
Prostaglandin F2-alpha receptor	0	2	1	3
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin D2 receptor	0	1	1	2
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
RGS12	1	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
DNA polymerase III, partial	2	0	0	2
isocitrate dehydrogenase 1, partial	2	0	0	2
LANA	0	0	0	1
NPYLR7B	0	0	1	1
serine-protein kinase ATM isoform a	2	0	0	2
lysosomal alpha-glucosidase preproprotein	9	0	0	9
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
serine/threonine-protein kinase PLK1	6	0	0	6
eyes absent homolog 2 isoform a	3	0	0	3
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
tumor susceptibility gene 101 protein	1	0	0	1
caspase-1 isoform alpha precursor	2	0	0	2
DNA dC->dU-editing enzyme APOBEC-3F isoform a	2	0	0	2
kelch-like ECH-associated protein 1	0	0	0	2
Multidrug resistance-associated protein 5	0	2	0	2
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	2	0	2
3',5'-cyclic-AMP phosphodiesterase	0	3	0	3
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Caspase-7	2	0	0	2
Inositol monophosphatase 1	8	0	0	8
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	3	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	3	0	3
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	3	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	3	0	3
Exopolyphosphatase PRUNE1	0	1	0	1
Equilibrative nucleoside transporter 1	0	2	0	2
Single-stranded DNA cytosine deaminase	2	0	0	2
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Phosphodiesterase	0	2	0	2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	2	0	3
Acetylcholinesterase	0	2	0	2
Acetylcholinesterase	0	1	0	1
Cholinesterase	0	2	0	2
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Amine oxidase [flavin-containing] A	0	2	0	2
Amine oxidase [flavin-containing] A	0	1	0	1
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	3	0	3
Amine oxidase [flavin-containing] B	0	1	0	1
Choline O-acetyltransferase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Cholinesterase	0	1	0	1
Acetylcholine receptor subunit epsilon	0	1	0	1
Cytochrome P450 1B1	0	1	0	1
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	2
Carboxylic ester hydrolase	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
Adenylate cyclase	0	1	0	1
Beta-2 adrenergic receptor	0	4	1	5
5-hydroxytryptamine receptor 1B	0	6	2	8
5-hydroxytryptamine receptor 5A	0	2	0	2
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
Flavin reductase (NADPH)	0	0	2	2
large T antigen	0	2	0	2
Pantothenate synthetase	0	2	0	2
Estrogen receptor	0	6	1	7
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	2	0	2
Sulfotransferase 1A1	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	2	0	2
Estrogen receptor beta	0	3	1	4
LMP1 [Human herpesvirus 4]	0	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	2	0	2
Regulatory protein E2	0	0	1	1
DNA topoisomerase 1	0	2	0	3
DNA topoisomerase 2	0	0	0	1
Caspase-3	0	1	0	1
DNA topoisomerase 2-alpha	0	0	0	1
Tubulin beta-2B chain	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit	0	2	0	2
Chain I, cAMP-dependent protein kinase inhibitor, alpha form	0	2	0	2
Chain B, Rho-associated protein kinase 1	0	2	0	2
Chain A, Rho-associated protein kinase 1	0	2	0	2
Chain A, Rho-associated protein kinase 1	0	2	0	2
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	2	0	2
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	2	0	2
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	2	0	2
Chain I, cAMP-dependent protein kinase inhibitor alpha	0	2	0	2
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	2	0	2
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	2	0	2
Chain I, cAMP-dependent protein kinase inhibitor alpha	0	2	0	2
Chain A, Rho-associated protein kinase 1	0	2	0	2
cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha1	0	0	0	1
serine/threonine-protein kinase 33 isoform a	0	0	0	1
Cell division cycle 7-related protein kinase	0	0	2	2
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	5	5
cAMP-dependent protein kinase catalytic subunit alpha	0	2	0	2
cAMP-dependent protein kinase catalytic subunit alpha	0	2	0	2
Tyrosine-protein kinase Fgr	0	0	4	4
C-C motif chemokine 2	0	2	0	2
Dual specificity protein kinase TTK	0	0	3	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	4	4
Choline-phosphate cytidylyltransferase A	0	0	2	2
Serine/threonine-protein kinase PLK1	0	0	5	5
Cell division control protein 42 homolog	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	0	2	2
Protein kinase C epsilon type	0	2	3	5
Protein kinase C zeta type	0	0	2	2
Myotonin-protein kinase	0	1	2	3
Rho-associated protein kinase 2	0	2	0	2
Serine/threonine-protein kinase N3	0	0	4	4
Serine/threonine-protein kinase Nek7	0	0	4	4
MAP/microtubule affinity-regulating kinase 4	0	0	5	5
Dual specificity testis-specific protein kinase 2	0	0	4	4
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Chain A, Dihydrofolate reductase	0	0	1	1
alpha-galactosidase	5	0	0	5
Thymidylate synthase	0	4	0	4
Thymidylate synthase	0	3	0	4
Dihydrofolate reductase	0	2	3	5
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
Cyclin-dependent kinase-like 5	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 4	0	0	4	4
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]	1	0	0	1
alpha synuclein, partial	1	0	0	1
luciferase	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	5	0	0	5
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
60 kDa chaperonin	0	1	0	1
Glutamate receptor ionotropic, kainate 1	1	2	1	4
Glutamate receptor ionotropic, kainate 2	1	2	1	4
Glutamate receptor ionotropic, kainate 3	1	2	0	3
Glutamate receptor ionotropic, kainate 4	1	2	0	3
Leukotriene B4 receptor 1	1	0	0	2
Glutamate receptor ionotropic, kainate 5	1	2	0	3
Leukotriene B4 receptor 2	1	0	0	2
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	3	0	0	3
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	4	0	4
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	1	3	1	5
Glutamate receptor 3	1	3	1	5
Glutamate receptor 4	1	3	1	5
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	2	3
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Cocaine esterase	0	1	0	1
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	2	0	2
Beta-2 adrenergic receptor	0	4	0	5
Integrin alpha-4	0	2	0	2
Carbonyl reductase [NADPH] 1	0	0	0	1
Beta-1 adrenergic receptor	0	4	1	6
5-hydroxytryptamine receptor 3A	0	1	0	1
Beta-3 adrenergic receptor	0	3	0	3
5-hydroxytryptamine receptor 2C	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
5-hydroxytryptamine receptor 2B	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Transporter	0	2	0	2
Cholecystokinin receptor type A	0	3	0	3
Protease	0	5	0	5
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Chain E, Fibrin beta chain	0	1	0	1
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
WRN	3	0	0	3
Mcl-1	0	1	0	1
MPI protein	0	1	0	1
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0	0	0	1
alkaline phosphatase, intestinal	0	0	1	1
pyruvate kinase	4	0	0	4
CDK5	0	0	0	1
major prion protein preproprotein Prp precursor	0	1	0	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	0	1	1
intestinal alkaline phosphatase precursor	0	0	1	1
Vif	0	1	0	1
Tat	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	1	0	3
alkaline phosphatase, germ cell type preproprotein	0	0	1	1
endoribonuclease toxin MazF	0	0	1	1
Pyruvate kinase PKM	0	1	0	1
Endothelin receptor type B	2	0	0	2
Endothelin-1 receptor	2	0	0	2
phosphoglycerate kinase	3	0	0	3
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Plasma kallikrein	0	0	0	3
Macrophage migration inhibitory factor	0	3	0	3
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Histamine H4 receptor	0	2	2	4
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
pyruvate kinase PKM isoform b	1	0	0	1
N-glycosylase/DNA lyase	0	2	0	2
Ornithine decarboxylase	1	0	0	1
Aspartate aminotransferase, cytoplasmic	0	1	0	1
Lactoperoxidase	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Urease subunit alpha	0	2	0	2
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Urease subunit beta	0	2	0	2
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	3	4
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha	0	1	0	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	1	2	3
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	2	2	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	2	3
Phosphatidylinositol 4-kinase alpha	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	2	3
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Serine/threonine-protein kinase 38	0	0	3	3
Phosphatidylinositol 3-kinase catalytic subunit type 3	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	1	2	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	3	3
Prostacyclin receptor	0	1	1	2
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Mast/stem cell growth factor receptor Kit	0	1	3	4
Platelet-derived growth factor receptor alpha	0	1	3	4
Cytochrome P450 3A5	0	0	0	1
Sodium-dependent noradrenaline transporter	0	1	0	1
D(2) dopamine receptor	0	1	0	1
Envelope glycoprotein	0	0	1	1
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Transporter	0	4	0	4
Leukotriene C4 synthase	0	0	2	2
Serine/threonine-protein kinase 25	0	0	2	2
Serine/threonine-protein kinase RIO3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 7	0	1	2	3
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	2	3
Peripheral plasma membrane protein CASK	0	0	2	2
Serine/threonine-protein kinase DCLK1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	2	2
Muscle, skeletal receptor tyrosine-protein kinase	0	0	2	2
Mitogen-activated protein kinase 13	0	1	2	3
Mitogen-activated protein kinase kinase kinase 13	0	0	2	2
Death-associated protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
NUAK family SNF1-like kinase 1	0	0	2	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	2	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	2	2
Serine/threonine-protein kinase PAK 3	0	0	2	2
Serine/threonine-protein kinase 17B	0	0	2	2
Cyclin-dependent kinase 14	0	0	2	2
Serine/threonine-protein kinase OSR1	0	0	2	2
Serine/threonine-protein kinase Chk2	0	0	2	2
RAF proto-oncogene serine/threonine-protein kinase	0	0	2	2
Macrophage colony-stimulating factor 1 receptor	0	0	2	2
Proto-oncogene tyrosine-protein kinase ROS	0	0	2	2
Wee1-like protein kinase 2	0	0	2	2
Uncharacterized serine/threonine-protein kinase SBK3	0	0	2	2
Insulin receptor-related protein	0	0	2	2
Vascular endothelial growth factor receptor 1	0	1	2	3
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	2	2
Serine/threonine-protein kinase MAK	0	0	2	2
Cyclin-dependent kinase 11B	0	0	2	2
Fibroblast growth factor receptor 2	0	0	2	2
Receptor tyrosine-protein kinase erbB-3	0	0	2	2
Fibroblast growth factor receptor 4	0	0	2	2
Fibroblast growth factor receptor 3	0	0	2	2
Protein kinase C eta type	0	0	3	3
Activin receptor type-2A	0	0	2	2
Ephrin type-A receptor 3	0	0	2	2
Ephrin type-A receptor 8	0	0	2	2
Leukocyte tyrosine kinase receptor	0	0	2	2
Tyrosine-protein kinase receptor UFO	0	0	2	2
Mitogen-activated protein kinase 4	0	0	2	2
G protein-coupled receptor kinase 4	0	0	2	2
Tyrosine-protein kinase receptor Tie-1	0	0	2	2
Vascular endothelial growth factor receptor 3	0	1	2	3
Vascular endothelial growth factor receptor 2	0	1	2	3
Megakaryocyte-associated tyrosine-protein kinase	0	0	2	2
Tyrosine-protein kinase TXK	0	1	2	3
Tyrosine-protein kinase ZAP-70	0	0	2	2
Cyclin-dependent kinase 8	0	0	2	2
Tyrosine-protein kinase Blk	0	1	2	3
Cytoplasmic tyrosine-protein kinase BMX	0	1	2	3
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	2	2
Serine/threonine-protein kinase Nek4	0	0	2	2
Death-associated protein kinase 1	0	0	2	2
Mitogen-activated protein kinase 12	0	1	2	3
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	2	3
Ephrin type-B receptor 1	0	0	2	2
Oxysterols receptor LXR-beta	0	1	0	1
Hormonally up-regulated neu tumor-associated kinase	0	0	2	2
Serine/threonine-protein kinase SIK1	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 4	0	0	2	2
Cell division control protein 2 homolog	0	0	2	2
Calcium-dependent protein kinase 1	0	0	2	2
Casein kinase II subunit alpha	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	2	2
SRSF protein kinase 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 9	0	0	2	2
Serine/threonine-protein kinase PknB	0	0	2	2
Cyclin-dependent kinase-like 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 10	0	0	2	2
Tyrosine-protein kinase receptor TYRO3	0	0	2	2
Cyclin-dependent kinase 18	0	0	2	2
Tyrosine-protein kinase ITK/TSK	0	1	2	3
Mitogen-activated protein kinase kinase kinase 12	0	0	2	2
Tyrosine-protein kinase Mer	0	0	2	2
Serine/threonine-protein kinase PAK 1	0	0	2	2
cGMP-dependent protein kinase 2	0	0	2	2
Serine/threonine-protein kinase PRP4 homolog	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1	0	0	2	2
Serine/threonine-protein kinase D1	0	0	3	3
Receptor tyrosine-protein kinase erbB-4	0	1	2	3
Ribosomal protein S6 kinase alpha-2	0	0	2	2
Rhodopsin kinase GRK1	0	0	2	2
NT-3 growth factor receptor	0	0	2	2
BDNF/NT-3 growth factors receptor	0	0	2	2
Mitogen-activated protein kinase 6	0	0	2	2
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	2	2
Serine/threonine-protein kinase SBK1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 19	0	0	2	2
Serine/threonine-protein kinase TNNI3K	0	0	2	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	0	2	2
Tyrosine-protein kinase JAK2	0	0	1	1
Serine/threonine-protein kinase Nek5	0	0	2	2
Dual serine/threonine and tyrosine protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 15	0	0	2	2
Serine/threonine-protein kinase tousled-like 2	0	0	2	2
Serine/threonine-protein kinase 32C	0	0	2	2
Serine/threonine-protein kinase pim-3	0	0	2	2
Serine/threonine-protein kinase VRK2	0	0	2	2
Myosin light chain kinase family member 4	0	0	2	2
Homeodomain-interacting protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1D	0	0	2	2
Cyclin-dependent kinase-like 3	0	0	2	2
Serine/threonine-protein kinase BRSK2	0	0	2	2
Serine/threonine-protein kinase NIM1	0	0	2	2
Serine/threonine-protein kinase ULK2	0	0	2	2
Serine/threonine-protein kinase DCLK2	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	2	2
Casein kinase I isoform alpha-like	0	0	2	2
Homeodomain-interacting protein kinase 4	0	0	2	2
Myosin-IIIa	0	0	2	2
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	2	2
Serine/threonine-protein kinase Nek11	0	0	2	2
Serine/threonine-protein kinase BRSK1	0	0	2	2
Serine/threonine-protein kinase 35	0	0	2	2
Rhodopsin kinase GRK7	0	0	2	2
Serine/threonine-protein kinase 32A	0	0	2	2
Myosin-IIIb	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	2	2
Cyclin-dependent kinase-like 2	0	0	2	2
Serine/threonine-protein kinase Sgk3	0	0	2	2
Atypical kinase COQ8B, mitochondrial	0	0	2	2
Cyclin-dependent kinase 15	0	0	2	2
SRSF protein kinase 1	0	0	2	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	2	2
Serine/threonine-protein kinase RIO1	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase RIO2	0	0	2	2
Cyclin-dependent kinase 19	0	0	2	2
Transient receptor potential cation channel subfamily M member 6	0	0	2	2
Testis-specific serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase 33	0	0	2	2
Serine/threonine-protein kinase DCLK3	0	0	2	2
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	2	2
Homeodomain-interacting protein kinase 2	0	0	2	2
Tyrosine-protein kinase Srms	0	0	2	2
Homeodomain-interacting protein kinase 3	0	0	2	2
Serine/threonine-protein kinase PLK3	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	2	2
Serine/threonine-protein kinase Nek6	0	0	2	2
SNF-related serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase LATS2	0	0	2	2
Serine/threonine-protein kinase 36	0	0	2	2
Serine/threonine-protein kinase 32B	0	0	2	2
Serine/threonine-protein kinase PLK2	0	0	2	2
Serine/threonine-protein kinase MARK1	0	0	2	2
Serine/threonine-protein kinase pim-2	0	0	2	2
Serine/threonine-protein kinase PAK 5	0	0	2	2
eIF-2-alpha kinase GCN2	0	0	2	2
Serine/threonine-protein kinase 17A	0	0	2	2
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	2	2
Ephrin type-A receptor 6	0	0	2	2
Death-associated protein kinase 2	0	0	2	2
Serine/threonine-protein kinase tousled-like 1	0	0	2	2
ALK tyrosine kinase receptor	0	0	2	2
SRSF protein kinase 3	0	0	2	2
Cyclin-dependent kinase 11A	0	0	2	2
Aurora kinase C	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	2	2
Microtubule-associated serine/threonine-protein kinase 1	0	0	2	2
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
Phospholipase A2, major isoenzyme	0	1	0	1
Androgen receptor	0	2	1	3
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	1	0	1
Caspase-1	0	2	0	3
Nitric oxide synthase, inducible	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Aldo-keto reductase family 1 member C3	0	2	0	2
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Lactoylglutathione lyase	0	2	0	2
Aldo-keto reductase family 1 member C1	0	1	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
matrix metalloproteinase 1, partial	0	0	1	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
hexokinase-4 isoform 1	3	0	0	3
glucokinase regulatory protein	3	0	0	3
Large neutral amino acids transporter small subunit 1	0	4	0	4
SLC16A10 protein	0	0	0	2
Monocarboxylate transporter 10	0	0	0	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	3
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	2	0	0	2
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	3	0	3
Reduced folate transporter	0	2	0	2
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Proton-coupled folate transporter	0	1	0	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Lanosterol 14-alpha demethylase	0	3	0	3
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Nuclear receptor corepressor 1	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A8	0	0	0	1
Presenilin-1	0	1	0	1
Presenilin-2	0	1	0	1
Gamma-secretase subunit APH-1B	0	1	0	1
Nicastrin	0	1	0	1
Gamma-secretase subunit APH-1A	0	1	0	1
Gamma-secretase subunit PEN-2	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	2	0	2
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	0	1	0	1
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Phospholipase A2, membrane associated	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Platelet-activating factor receptor	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Adenosine receptor A1	0	3	0	3
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Potassium channel subfamily K member 2	0	1	0	1
Beta-2 adrenergic receptor	0	1	1	4
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Interstitial collagenase	0	2	0	2
Aromatase	0	1	0	1
Sodium/iodide cotransporter	0	1	0	1
5-hydroxytryptamine receptor 3E	0	2	0	2
5-hydroxytryptamine receptor 3B	0	2	0	2
5-hydroxytryptamine receptor 3A	0	2	0	2
5-hydroxytryptamine receptor 3D	0	2	0	2
5-hydroxytryptamine receptor 3C	0	2	0	2
Chain A, ARGINASE 1	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Chain A, ARGINASE 1	0	1	0	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE	0	1	0	1
Nrf2	1	0	0	1
Microphthalmia-associated transcription factor	0	0	0	1
caspase recruitment domain family, member 15	0	1	0	1
receptor-interacting serine/threonine-protein kinase 2 isoform 1	0	1	0	1
Beta lactamase (plasmid)	0	1	0	1
Valosin-containing protein	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Chain A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
Serine hydroxymethyltransferase, mitochondrial	0	1	0	1
CREB-binding protein	1	0	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	2	0	2
Beta-lactamase	0	0	0	1
streptokinase A precursor	0	0	1	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
Beta-lactamase	0	0	0	1
Cytochrome P450 1A2	0	0	0	2
Arylacetamide deacetylase	0	1	0	3
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	2	0	2
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Muscarinic acetylcholine receptor M1	0	0	1	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Sodium/potassium/calcium exchanger 4	0	1	1	2
Taste receptor type 2 member 14	0	0	1	2
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Sodium/potassium/calcium exchanger 2	0	1	1	2
luciferase	0	0	0	1
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Solute carrier family 22 member 4	0	1	0	1
DNA (cytosine-5)-methyltransferase 3-like	0	1	0	1
DNA (cytosine-5)-methyltransferase 3A	0	1	0	1
Histamine H2 receptor	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
heat shock protein 90, putative	0	0	0	1
Beta-1 adrenergic receptor	0	1	1	3
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	1	1	2
Cholecystokinin receptor type A	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Vasopressin V1a receptor	0	1	1	2
Beta-2 adrenergic receptor	0	1	0	1
Sodium/bile acid cotransporter	0	2	0	2
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
NS5	0	0	1	1
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	2	2
Adenosylhomocysteinase	0	0	0	2
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Estrogen receptor beta	0	1	0	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	1	0	2
Cystathionine gamma-lyase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Aldo-keto reductase family 1 member A1	0	2	0	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Chain A, Glutathione S-transferase	0	1	0	1
Tumor necrosis factor	0	0	1	1
Fibroblast growth factor 1	0	0	1	1
Cystine/glutamate transporter	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Solute carrier family 22 member 12	0	1	0	1
Hematopoietic prostaglandin D synthase	0	1	0	1
Carboxypeptidase M	0	1	0	1
5-hydroxytryptamine receptor 1E	0	1	0	1
5-hydroxytryptamine receptor 1F	0	2	1	3
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
Protein kinase C gamma type	0	1	1	2
Luciferin 4-monooxygenase	0	0	1	1
Ras guanyl-releasing protein 3	0	0	1	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Chain A, Tyrosine-protein kinase	0	1	0	1
Chain A, Tyrosine-protein kinase	0	1	0	1
Chain A, Tyrosine-protein kinase JAK2	0	1	0	1
Serine/threonine-protein kinase Sgk1	0	1	0	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Tubulin alpha-1A chain	0	0	1	1
Tyrosine-protein kinase JAK3	0	1	0	1
Tyrosine-protein kinase JAK2	0	1	0	1
Tyrosine-protein kinase JAK3	0	1	0	1
Trace amine-associated receptor 1	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Olfactory receptor 51E2	0	0	1	1
Valacyclovir hydrolase	0	0	0	1
Chain A, Arginase 1	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Adenosylhomocysteinase	0	1	0	1
Adenosine deaminase	0	0	0	1
RNA-directed RNA polymerase	0	1	1	2
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
POsterior Segregation	0	0	1	1
Alpha-1A adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
M-phase inducer phosphatase 1	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Zinc finger protein mex-5	0	0	1	1
Butyrophilin subfamily 3 member A1	0	0	1	2
Neutrophil collagenase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
Matrix metalloproteinase-14	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	2	0	2
H	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Aldo-keto reductase family 1 member C21	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

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Studies (1,814)

Protein Targets (2,072)

Giant Cell Arteritis

Synonyms(1)

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Overview

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Treatment

Research

Studies (1,814)

Drugs Studied (264)

Protein Targets (2,072)