Page last updated: 2024-08-05 11:42:31
methylindole
Any member of the class of indoles carrying one or more methyl substituents.
ChEBI ID: 38460
Members (12)
| Member | Definition | Role |
|---|---|---|
| [1-[(7-chloro-3-methyl-1H-indol-2-yl)methyl]-4-(2-phenoxyethyl)-4-piperidinyl]methanol | [1-[(7-chloro-3-methyl-1H-indol-2-yl)methyl]-4-(2-phenoxyethyl)-4-piperidinyl]methanol | |
| 2-(1H-benzimidazol-2-ylthio)-1-(2,3-dimethyl-1-indolyl)ethanone | 2-(1H-benzimidazol-2-ylthio)-1-(2,3-dimethyl-1-indolyl)ethanone | |
| 2-methylindole | A methylindole that is 1H-indole substituted by a methyl group at position 2. | 2-methyl-1H-indole |
| 3-(2,3-dimethyl-1H-indol-5-yl)-4-methyl-1H-1,2,4-triazole-5-thione | 3-(2,3-dimethyl-1H-indol-5-yl)-4-methyl-1H-1,2,4-triazole-5-thione | |
| 3-(2,3-dimethyl-1H-indol-5-yl)-4-prop-2-enyl-1H-1,2,4-triazole-5-thione | 3-(2,3-dimethyl-1H-indol-5-yl)-4-prop-2-enyl-1H-1,2,4-triazole-5-thione | |
| 3-hydroxy-3-methyloxindole | A methylindole that is 1,3-dihydro-2H-indol-2-one substituted by methyl and a hydroxy group at position 3. | 3-hydroxy-3-methyloxindole |
| 3-methyloxindole | A member of the class of oxindoles that is oxindole (1,3-dihydro-2H-indol-2-one) in which one of the hydrogens at position 3 has been replaced by a methyl group. | 3-methyloxindole |
| 4,7-dimethoxy-2,3-dimethyl-1H-indole | 4,7-dimethoxy-2,3-dimethyl-1H-indole | |
| bopindolol | A methylindole that is 2-methyl-1H-indol-4-ol in which the hydrogen of the hydroxy group is replaced by a 2-(benzoyloxy)-3-(tert-butylamino)propyl group. | 1-(tert-butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]propan-2-yl benzoate |
| l 655240 | 3-[1-[(4-chlorophenyl)methyl]-5-fluoro-3-methyl-2-indolyl]-2,2-dimethylpropanoic acid | |
| panobinostat | A hydroxamic acid obtained by formal condensation of the carboxy group of (2E)-3-[4-({[2-(2-methylindol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enoic acid with the amino group of hydroxylamine. A histone deacetylase inhibitor used (as its lactate salt) in combination with bortezomib and dexamethasone for the treatment of multiple myeloma. | panobinostat |
| skatole | A methylindole carrying a methyl substituent at position 3. It is produced during the anoxic metabolism of L-tryptophan in the mammalian digestive tract. | skatole |
Research
Studies (1,448)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 261 (18.02) | 18.7374 |
| 1990's | 153 (10.57) | 18.2507 |
| 2000's | 169 (11.67) | 29.6817 |
| 2010's | 685 (47.31) | 24.3611 |
| 2020's | 180 (12.43) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 158 (10.27%) | 5.53% |
| Reviews | 102 (6.63%) | 6.00% |
| Case Studies | 10 (0.65%) | 4.05% |
| Observational | 1 (0.07%) | 0.25% |
| Other | 1,267 (82.38%) | 84.16% |