Any dicarboxylic acid carrying a hydroxy group on the carbon atom at position alpha to the carboxy group.
ChEBI ID: 50263
| Member | Definition | Role |
|---|---|---|
| 2-hydroxymuconic acid | A hexadienedioic acid compound having a 2-hydroxy substituent and with configuration (2Z,4E). | (2Z,4E)-2-hydroxymuconic acid |
| alpha-hydroxyglutarate | A 2-hydroxydicarboxylic acid that is glutaric acid in which one hydrogen alpha- to a carboxylic acid group is substituted by a hydroxy group. | 2-hydroxyglutaric acid |
| dihydroxyfumarate | A 2-hydroxydicarboxylic acid consisting of fumaric acid having two hydroxy groups at the 2- and 3-positions. | dihydroxyfumaric acid |
| malic acid | A 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group. | malic acid |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 432 (14.42) | 18.7374 |
| 1990's | 366 (12.22) | 18.2507 |
| 2000's | 680 (22.70) | 29.6817 |
| 2010's | 1,173 (39.15) | 24.3611 |
| 2020's | 345 (11.52) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 36 (1.15%) | 5.53% |
| Reviews | 135 (4.33%) | 6.00% |
| Case Studies | 80 (2.57%) | 4.05% |
| Observational | 4 (0.13%) | 0.25% |
| Other | 2,862 (91.82%) | 84.16% |