Any piperazinone that has a piperazine-2,5-dione skeleton.
| Member | Definition | Role |
|---|
| 2,5-dioxopiperazine | A cyclic peptide that is piperazine in which the hydrogens at positions 2 and 5 are replaced by oxo groups. | piperazine-2,5-dione |
| albonoursin | A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione in which the two hydrogen at position 3 and those at position 6 are replaced by benzylidene and isobutylidene groups (the 3Z,6Z-geoisomer). | albonoursin |
| cyclo(L-tryptophyl-L-alanyl) | | cyclo(L-tryptophyl-L-alanyl) |
| cyclo(leucyl-phenylalanyl) | A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione in which one hydrogen at position 3 and one hydrogen at position 6 are replaced by benzyl and isobutyl groups (the 3S,6S-diastereomer). | cyclo(L-phenylalanyl-L-leucyl) |
| cyclo(phenylalanyl-phenylalanyl) | A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione in which one hydrogen at position 3 and one hydrogen at position 6 are replaced by benzyl groups (the 3S,6S-diastereomer). | cyclo(L-phenylalanyl-L-phenylalanyl) |
| cyclo(tyrosyl-tyrosyl) | A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione in which one hydrogen at position 3 and one hydrogen at position 6 are replaced by p-hydroxybenzyl groups. | cyclo(tyrosyl-tyrosyl) |
| echinuline | An indole alkaloid with formula C29H39N3O2. It is a fungal metabolite found in several Aspergillus species. | echinulin |
| mycocyclosin | An organic heterotetracyclic compound obtained via intramolecular oxidative aromatic coupling of cyclo(L-tyrosyl-L-tyrosyl). | mycocyclosin |
| n(alpha)-acetylfusarinines | A member of the class of 2,5-diketopiperazines that is 2,5-diketopiperazine which is substituted at positions 3 and 6 by 3-(hydroxyamino)propyl groups in which the nitrogens have been acylated by (2E)-5-hydroxy-3-methylpent-2-enoyl groups. The substituent at position 3 has been further modified by having its terminal hydroxy group esterified by condensation with the carboxy group of N(2)-acetyl-N(5)-hydroxy-L-ornithine in which the N(5) nitrogen has been acylated by a (2E)-5-hydroxy-3-methylpent-2-enoyl group. | desferricoprogen |
| npi 2358 | A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione substituted by benzylidene and (5-tert-butyl-1H-imidazol-4-yl)methylidene groups at positions 3 and 6, respectively. It is a vascular disrupting agent and a microtubule destabalising agent which was in clinical trials (now discontinued) for the treatment of non-small cell lung cancer. | plinabulin |
| preechinulin | | preechinulin |
| rhodotorulic acid | A member of the class of 2,5-diketopiperazines obtained by cyclodimerisation of N(5)-acetyl-N(5)-hydroxy-L-ornithine. | rhodotorulic acid |
| tardioxopiperazine a | | tardioxopiperazine A |