Page last updated: 2024-09-27

Pyomyositis

An intramuscular suppuration of the large skeletal muscle groups. It is associated with INFECTION such as STAPHYLOCOCCUS AUREUS and PYODERMA. It was known as a tropical disease but is increasing among the immunocompromised (IMMUNOCOMPROMISED HOST). Symptoms include muscle pain, FEVER, and leucocytosis. It has been diagnosed by MRI SCANS.

Synonyms(2)

Synonym
Pyomyositis
Tropical Myositis

Research Excerpts

Overview

ExcerptReference
"Tropical pyomyositis is very rarely associated with rheumatoid arthritis."( Kaushik, R; Kaushik, RM; Mahajan, SK; Sharma, A, 2006)
"Iliopsoas pyomyositis is a new manifestation of community-acquired MRSA in the obstetric population that may masquerade as benign musculoskeletal back pain."( Choi, C; Kreye, E; Miller, LG; Sokolov, KM; Tang, AW, 2007)
"Pyomyositis is a purulent infection of skeletal muscle characterized by fever, localized muscle pain and stiffness, swelling and tenderness."( Ikeda, T; Ito, T; Kimura, F; Kobayashi, A; Kobayashi, S; Motoyoshi, K; Ogura, K; Saionji, K; Saito, D; Sato, K; Torikai, H, 2008)
"Pyomyositis is a musculoskeletal infection with formation of an intramuscular abscess."( Gay, H; Giles, H; Hull, R; Nowicki, M, 2008)
"Pyomyositis is an infection of skeletal muscle that involves the formation of intramuscular abscesses."( Chang, FY; Chiu, SK, 2009)
"Pyomyositis is a commonly encountered condition in the tropics."( Bassi, R; Bruce, CE; George, H; Perry, DC; Unnikrishnan, PN, 2010)
"Pyomyositis is an unusual but potentially serious disease in children."( Anthony, EY; Shetty, AK; Wong, SL, 2009)
"Primary pyomyositis is infection of the skeletal muscles in the absence of adjacent skin, soft tissue, and bone infection."( Bambery, P; Kumar, S; Sharma, A; Sharma, K; Sharma, N; Singh, R; Singh, S; Varma, S; Wanchu, A, 2010)
"Although pyomyositis is a rare disease, it should be considered in the differential diagnosis of immediate onset of musculoskeletal pain in children."( Berisa, AE; Georgoulis, AD; Lykissas, MG; Manoudis, GN; Mitsionis, GI; Motsis, E; Sionti, I, 2009)
"Pyomyositis is a purulent infection of skeletal muscles that arise from hematogenous spread associated with abscess formation."( Agrawal, S; Narsimulu, G; Prabhu, VN; Thomas, J; Varaprasad, IR, 2010)
"Pyomyositis is a rare complication of chemotherapy that is commonly seen in tropical climates and in patients with immunodeficiency states."( Blomfield, P; Chan, W; McIntosh, R; Singh, P, 2010)
"Piriformis pyomyositis is defined as a subacute infection of skeletal muscles associated with systemic infectious symptoms."( Fitzpatrick, C; McGuinness, E; Meaney, J; Mullers, S; O'Connell, MP; Wong, LF, 2012)
"Pyomyositis is a pyogenic muscular tissue infection mainly occurring in immunocompromised patients."( Chen, MC; Chen, SH; Chong, PN; Yang, SH; Yao, TK, 2011)
"Primary pyomyositis is a subacute deep bacterial infection of skeletal muscle."( Butt, DA; Hadjipavlou, M; McAllister, J, 2012)
"Pyomyositis is a rare complication of chemotherapy for non-hematological malignancies."( Aihara, S; Hashiguchi, M; Iwasaka, T; Nakao, Y; Nishiyama, S; Noguchi, M; Yasunaga, M; Yokoyama, M, 2013)
"Pyomyositis is etiologically attributed to an infection and predominantly affects large limb or trunk muscles."( Kubat, B, 2013)
"Pyomyositis is a rarely encountered infection among diabetics, which usually affects lower extremities."( Gounari, P; Kougias, M; Sioula, E; Skourtis, A; Vallianou, N, 2013)
"Primary pyomyositis is a rare bacterial infection of the skeletal muscle."( Dacombe, PJ; Evans, J; Gosling, OB; Heal, J, 2013)
"Pyomyositis is a bacterial infection of skeletal muscle that often results in deep intramuscular abscesses."( Kumar, MP; Mailhot, T; Perera, P; Seif, D, 2014)
"Pyomyositis is a rare, subacute, deep pyogenic infection of the muscle tissue."( Endo, Y; Ishida, M; Mekata, E; Minamiguchi, H; Ohta, H; Shimizu, T; Sonoda, H; Takebayashi, K; Tani, M; Tani, T, 2016)
"Pyomyositis is an acute bacterial infection of skeletal muscle that results in localized abscess formation."( Chiarelli, F; Comegna, L; Di Filippo, P; Franchini, S; Guidone, PI; Mohn, A; Petrosino, MI; Prezioso, G; Rossi, N, 2016)
"Pyomyositis is typically found in tropical areas but its rates in temperate climates have been rising."( Hassan, S; Hiddema, J; Mangat, N; Siddiqui, N, 2017)
"Pyomyositis is almost universally caused by gram-positive organisms and while the recent emergence of invasive disease due to hypervirulent K."( Kempker, RR; Kumar, S; Mgbemena, O; Serota, DP; Weiss, DS; Wozniak, JE, 2017)
"Pyomyositis is the infection of skeletal muscle, a rare pathology in children."( Biondi, EJ; Carballo, CM; López, EL; Medranda, AC; Orlando, MN; Pannunzio, ME; Praino, ML; Vázquez, MS, 2019)
"Pyomyositis is a purulent infection of striated muscle and postoperative management remains the mainstay."( Pen Hung, DC; Yung Tan, DH, 2022)
"Pyomyositis is a microbial infection of the muscles and contributes to local abscess formation."( Hisatsune, J; Ishiguro, C; Iwao, Y; Kutsuno, S; Nakanishi, Y; Sakabe, S; Sugai, M; Tanaka, H; Tanigawa, M; Toyoshima, H, 2023)
"Pyomyositis is an unusual bacterial infection but potential severe in children."( Barchi, L; Bassoli, I; Bonvicini, F; De Fanti, A; Fastiggi, M; Iughetti, L; Silvotti, M, 2023)

Treatment

ExcerptReference
"Following the treatment for pyomyositis, there was no cancer recurrence or evidence of any recurrent pyomyositis."( Endo, Y; Ishida, M; Mekata, E; Minamiguchi, H; Ohta, H; Shimizu, T; Sonoda, H; Takebayashi, K; Tani, M; Tani, T, 2016)

Research

Studies (98)

TimeframeStudies, This Condition (%)All Conditions %
pre-19902 (2.04)23.3326
1990's0 (0.00)12.5806
2000's25 (25.51)18.1394
2010's63 (64.29)28.8240
2020's8 (8.16)9.53
DrugIndicatedRelationship StrengthStudiesTrials
cefuroxime0low20
ciprofloxacin0low30
fentanyl0low10
gentamicin0low10
leflunomide0low10
metronidazole0low40
risperidone0low10
sulfamethoxazole0low10
trimethoprim0low10
prednisolone0low20
prednisone0low10
penicillin g0low10
methicillin0low30
cloxacillin0low60
oxacillin0low20
ampicillin0low10
penicillanic acid0low10
benzoyl peroxide0low10
isoxazoles0low10
vancomycin0medium161
dicloxacillin0low10
floxacillin0low40
calcium pyrophosphate0low10
trolamine salicylate0low20
cefazolin0low40
amoxicillin0low10
paclitaxel0low10
amikacin0low10
piperacillin0low10
itraconazole0low10
cephalosporin c0low20
fluorodeoxyglucose f180low10
arbekacin0low10
imatinib mesylate0low20
beta-lactams0low10
docetaxel anhydrous0low10
levofloxacin0low10
ertapenem0low10
trimethoprim, sulfamethoxazole drug combination0low10
carboplatin0low20
glycogen0low10
meropenem0low50
mycophenolic acid0low10
clindamycin0low90
zithromax0low10
dibekacin0low10
micafungin0low10
amphotericin b0low10
morphine0low10
amoxicillin-potassium clavulanate combination0low10
paliperidone palmitate0low10
oligonucleotides0low10
ro13-99040low100
piperacillin, tazobactam drug combination0low10
chlortetracycline0low10
minocycline0low10
tigecycline0low10
technetium tc 99m sulfur colloid0low10
daptomycin0low20
exudates0low10
rifampin0low20

Protein Targets (631)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
estrogen nuclear receptor alpha210021
peripheral myelin protein 227007
histone acetyltransferase KAT2A isoform 14004
lamin isoform A-delta10110011
ATP-binding cassette sub-family C member 3017017
Multidrug resistance-associated protein 4017019
Bile salt export pump023023
Canalicular multispecific organic anion transporter 1017017
Aminoglycoside 3'-phosphotransferase 0001
ATP-dependent phosphofructokinase3003
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE6006
Chain A, Beta-lactamase3003
Chain A, 2-oxoglutarate Oxygenase6006
Beta-lactamase 0003
Beta-lactamase 0004
Beta-lactamase 0005
Beta-lactamase 0004
AR protein150015
apical membrane antigen 1, AMA13003
Beta-lactamase 0004
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 12002
DNA polymerase iota isoform a (long)4004
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
DNA polymerase kappa isoform 13003
Bile salt export pump0808
Beta-lactamase SHV-10004
Beta-lactamase SHV-10005
Cytochrome P450 2C9 0606
Beta-lactamase0005
Kappa-type opioid receptor0408
Solute carrier family 15 member 1011011
Solute carrier family 15 member 10202
Cytochrome P450 2J20404
B2 metallo-beta-lactamase 0004
Solute carrier family 15 member 20707
Beta-lactamase 0004
Beta-lactamase 0004
Solute carrier family 15 member 20707
Beta-lactamase 0004
Beta-lactamase 0004
Chain A, HADH2 protein6006
Chain B, HADH2 protein6006
Chain A, Cruzipain4004
interleukin 85005
phosphopantetheinyl transferase5005
GLS protein3003
glucocorticoid receptor [Homo sapiens]110011
farnesoid X nuclear receptor8008
peroxisome proliferator-activated receptor delta8008
vitamin D (1,25- dihydroxyvitamin D3) receptor9009
tumor necrosis factor1001
vitamin D3 receptor isoform VDRA5005
nuclear factor erythroid 2-related factor 2 isoform 1130013
Cytochrome P450 1A20303
Cytochrome P450 3A40517
Cytochrome P450 2D60303
Cytochrome P450 2C190202
Nuclear receptor ROR-gamma3003
Potassium voltage-gated channel subfamily H member 2011012
Aurora kinase B0101
Broad substrate specificity ATP-binding cassette transporter ABCG20303
Chain A, Mutant Al2 6e7p9g0011
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Beta-lactamase 0104
acid sphingomyelinase2002
GLI family zinc finger 3110011
retinoic acid nuclear receptor alpha variant 18008
Beta-lactamase 0104
Beta-lactamase 0005
Metallo-beta-lactamase type 20016
Metallo-beta-lactamase VIM-11 0004
euchromatic histone-lysine N-methyltransferase 27007
Metallo-beta-lactamase VIM-20004
Beta-lactamase 0006
Metallo-beta-lactamase0004
Beta-lactamase 0104
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
chromobox protein homolog 13003
thyroid hormone receptor beta isoform 2100010
DNA polymerase beta3003
geminin100010
Carbonic anhydrase 10101
Carbonic anhydrase 20101
60 kDa heat shock protein, mitochondrial0404
Beta-lactamase OXA-70005
Spike glycoprotein7018
10 kDa heat shock protein, mitochondrial0404
Angiopoietin-1 receptor0011
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Thiosulfate sulfurtransferase0404
Metallo-beta-lactamase VIM-130005
Efflux transporter 0103
Beta-lactamase 0004
Beta-lactamase Toho-10003
Beta-lactamase 0103
Class D beta-lactamase0004
60 kDa chaperonin 0404
Metallo-beta-lactamase0003
Beta-lactamase 0004
Beta-lactamase 0014
10 kDa chaperonin 0404
Metallo-b-lactamase 0007
Carbapenem-hydrolyzing beta-lactamase KPC0005
Histamine H3 receptor0004
Beta-lactamase class B VIM-2 0018
Beta-lactamase VIM-1 0005
acetylcholinesterase7007
thyroid hormone receptor beta isoform a3003
Chain A, TYROSYL-DNA PHOSPHODIESTERASE3003
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
RAR-related orphan receptor gamma8008
estrogen receptor 2 (ER beta)6006
G4004
cytochrome P450 2D64004
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
Interferon beta7007
HLA class I histocompatibility antigen, B alpha chain 4004
Inositol hexakisphosphate kinase 14004
cytochrome P450 2C9, partial4004
Chain A, JmjC domain-containing histone demethylation protein 3A3003
Luciferase5005
thioredoxin reductase5005
Smad32002
Solute carrier family 22 member 60303
Solute carrier family 22 member 60202
Solute carrier family 22 member 80303
Solute carrier family 22 member 110202
Solute carrier family 22 member 80304
Beta-lactamase 0104
Beta-lactamase 0002
Metallo-beta-lactamase VIM-19 0005
Beta-lactamase 0003
Albumin0044
Beta-lactamase 0002
Beta-lactamase 0003
Metallo-beta-lactamase VIM-20004
Solute carrier family 22 member 70101
BlaVIM-1 0004
Beta-lactamase 0002
Beta-lactamase 0003
Solute carrier family 22 member 70101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
P2Y purinoceptor 120101
Protein-arginine deiminase type-40909
TDP1 protein140014
aldehyde dehydrogenase 1 family, member A18008
EWS/FLI fusion protein8008
cytochrome P450 2C9 precursor2002
Gamma-aminobutyric acid receptor subunit pi4105
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0102
DNA gyrase subunit A0103
DNA gyrase subunit B0103
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0102
DNA topoisomerase 2-alpha0104
Gamma-aminobutyric acid receptor subunit beta-14105
Gamma-aminobutyric acid receptor subunit delta4105
Gamma-aminobutyric acid receptor subunit gamma-24105
Gamma-aminobutyric acid receptor subunit alpha-54105
Gamma-aminobutyric acid receptor subunit alpha-34105
DNA gyrase subunit A0102
Gamma-aminobutyric acid receptor subunit gamma-14105
Gamma-aminobutyric acid receptor subunit alpha-24105
Gamma-aminobutyric acid receptor subunit alpha-44105
Gamma-aminobutyric acid receptor subunit gamma-34105
Gamma-aminobutyric acid receptor subunit alpha-64105
Multidrug resistance protein MdtK0011
Histamine H2 receptor3003
Gamma-aminobutyric acid receptor subunit alpha-14105
Gamma-aminobutyric acid receptor subunit beta-34105
Gamma-aminobutyric acid receptor subunit beta-24105
DNA gyrase subunit B0202
DNA gyrase subunit A0303
Enoyl-[acyl-carrier-protein] reductase [NADH]0102
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Integrase 0101
GABA theta subunit4105
Gamma-aminobutyric acid receptor subunit epsilon4105
Solute carrier family 22 member 80506
Beta-lactamase TEM0204
PPM1D protein3003
caspase 7, apoptosis-related cysteine protease2002
nuclear receptor subfamily 1, group I, member 37007
cytochrome P450 family 3 subfamily A polypeptide 48008
estrogen-related nuclear receptor alpha130013
pregnane X nuclear receptor110011
67.9K protein4004
peroxisome proliferator activated receptor gamma4004
caspase-32002
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a6006
thyroid stimulating hormone receptor5005
nuclear receptor subfamily 1, group I, member 25005
Cellular tumor antigen p539009
Serum paraoxonase/arylesterase 10202
Kinesin-like protein KIF110101
ATPase family AAA domain-containing protein 55005
Ataxin-25005
Nucleotide-binding oligomerization domain-containing protein 20202
potassium voltage-gated channel subfamily H member 2 isoform d2002
Solute carrier family 22 member 1 0303
Nuclear receptor subfamily 1 group I member 20022
ATP-dependent translocase ABCB10307
D(2) dopamine receptor0303
Amine oxidase [flavin-containing] A0202
D(4) dopamine receptor0202
Amine oxidase [flavin-containing] B0101
Delta-type opioid receptor0304
Delta-type opioid receptor0416
Mu-type opioid receptor0429
Kappa-type opioid receptor0315
Histamine H1 receptor0303
Mu-type opioid receptor0427
D(3) dopamine receptor0303
Delta-type opioid receptor0618
Kappa-type opioid receptor0416
Mu-type opioid receptor0316
Mu-type opioid receptor0505
Sigma non-opioid intracellular receptor 10202
Sigma non-opioid intracellular receptor 10404
Sigma non-opioid intracellular receptor 10101
Chain A, Dihydrofolate reductase0011
Chain A, Ferritin light chain1001
glp-1 receptor, partial5005
USP1 protein, partial2002
thyroid stimulating hormone receptor6006
retinoid X nuclear receptor alpha100010
glucocerebrosidase1001
alpha-galactosidase1001
activating transcription factor 65005
lysosomal alpha-glucosidase preproprotein1001
nuclear factor erythroid 2-related factor 2 isoform 25005
Thymidylate synthase0303
Thymidylate synthase0101
Dihydrofolate reductase0213
Aldo-keto reductase family 1 member B10101
Alpha-synuclein2103
Folylpolyglutamate synthase, mitochondrial0001
Solute carrier organic anion transporter family member 1A30101
Folylpolyglutamate synthase, mitochondrial0001
Multidrug resistance associated protein0001
Genome polyprotein 0101
Spike glycoprotein0011
Replicase polyprotein 1ab0112
Transmembrane protease serine 20011
Procathepsin L0011
Muscarinic acetylcholine receptor M20303
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0415
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0112
Muscarinic acetylcholine receptor M10202
Alpha-2B adrenergic receptor0303
Alpha-2C adrenergic receptor0303
Muscarinic acetylcholine receptor M30303
Alpha-1D adrenergic receptor0404
Sigma intracellular receptor 20101
Cyclic GMP-AMP synthase0101
Angiotensin-converting enzyme 2 0011
Toll-like receptor 90101
Toll-like receptor 70101
SMAD family member 22002
SMAD family member 32002
progesterone receptor6006
IDH14004
aryl hydrocarbon receptor5005
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
serine/threonine-protein kinase mTOR isoform 11001
DNA repair protein RAD52 homolog isoform a0001
Voltage-dependent calcium channel gamma-2 subunit6006
Tyrosine-protein kinase ABL10213
Cytochrome P450 2C80001
Mast/stem cell growth factor receptor Kit0112
Breakpoint cluster region protein0011
Platelet-derived growth factor receptor alpha0112
Glutamate receptor 26107
Cytochrome P450 3A50001
hypoxia-inducible factor 1 alpha subunit3003
Fumarate hydratase2002
GALC protein1001
polyprotein2002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
heat shock protein beta-12002
Cytochrome P450 1440011
Steroid C26-monooxygenase0011
Steroid C26-monooxygenase0011
matrix metalloproteinase 1, partial0011
ATAD5 protein, partial2002
Thrombopoietin1001
nonstructural protein 11001
Parkin1001
P531001
arylsulfatase A1001
pyruvate kinase1001
v-jun sarcoma virus 17 oncogene homolog (avian)3003
Bloom syndrome protein isoform 12002
NPC intracellular cholesterol transporter 1 precursor2002
peripheral myelin protein 22 isoform 12002
cellular tumor antigen p53 isoform a1001
cytochrome P450 2C19 precursor3003
histone deacetylase 9 isoform 31001
huntingtin isoform 21001
ras-related protein Rab-9A1001
nuclear receptor ROR-gamma isoform 12002
survival motor neuron protein isoform d3003
cytochrome P450 3A4 isoform 14004
muscarinic acetylcholine receptor M13003
neuropeptide S receptor isoform A1001
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Integrin beta-31102
Aldo-keto reductase family 1 member B10202
Integrin alpha-IIb1001
Endothelin receptor type B1001
Sodium-dependent noradrenaline transporter 0202
Endothelin-1 receptor1102
Sodium-dependent dopamine transporter 0202
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
CAAX prenyl protease 2 isoform 20001
streptokinase A precursor0044
Tubulin beta-4A chain0214
Tubulin beta chain0214
Tubulin alpha-3C chain0214
Tubulin alpha-1B chain0214
Tubulin alpha-4A chain0214
Tubulin beta-4B chain0214
Fatty-acid amide hydrolase 10101
DNA primase0101
Tubulin beta-3 chain0315
Tubulin beta-2A chain0214
Tubulin beta-8 chain0214
Tubulin alpha-3E chain0214
Tubulin alpha-1A chain0214
Multidrug and toxin extrusion protein 10202
Tubulin alpha-1C chain0214
Tubulin beta-6 chain0214
Tubulin beta-2B chain0214
Tubulin beta-1 chain0214
lethal factor (plasmid)3003
Beta-lactamase0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase IMP-1 0002
Beta-lactamase 0002
Thioredoxin reductase 0101
Histone H2A.x3003
mitogen-activated protein kinase 11001
muscleblind-like protein 1 isoform 11001
Flavodoxin0001
Voltage-dependent L-type calcium channel subunit alpha-1F0303
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
TAR DNA-binding protein 433003
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Voltage-dependent L-type calcium channel subunit alpha-1C0404
Lanosterol 14-alpha demethylase0202
Stromelysin-10101
Matrilysin0101
Multidrug transporter MdfA0101
Matrix metalloproteinase-90101
Protein mono-ADP-ribosyltransferase PARP150101
Opioid receptor, delta 1b 0101
Acetylcholinesterase0101
Opioid receptor homologue0101
ATP-dependent translocase ABCB10101
Acyl-CoA desaturase 10101
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
Muscarinic acetylcholine receptor M20101
Translocator protein0011
Histidine decarboxylase0011
ATP-dependent translocase ABCB10202
Proteinase-activated receptor 10112
Sodium-dependent serotonin transporter0303
Kappa-type opioid receptor0214
UDP-glucuronosyltransferase 1A30001
Nociceptin receptor0101
5-hydroxytryptamine receptor 70202
Mu-type opioid receptor0101
Beta-2 adrenergic receptor0101
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
UDP-glucuronosyltransferase 1A90001
Inosine-5'-monophosphate dehydrogenase 20202
Glutamate receptor 10101
Glutamate receptor 30101
Glutamate receptor 40101
Inosine-5'-monophosphate dehydrogenase 1 0202
UDP-glucuronosyltransferase 1A1 0102
Peroxisome proliferator-activated receptor gamma0011
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A70001
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
MecA 0101
Genome polyprotein 0101
pregnane X receptor2002
Epidermal growth factor receptor0101
Tubulin alpha-1A chain0012
Tubulin beta chain0011
Receptor tyrosine-protein kinase erbB-20101
Tyrosine-protein kinase Fyn0101
Integrin alpha-V 0101
60 kDa chaperonin0101
Botulinum neurotoxin type A 0101
Apoptosis regulator Bcl-20101
Fibroblast growth factor receptor 10101
Proto-oncogene tyrosine-protein kinase Src0101
UDP-glucuronosyltransferase 2B70101
UDP-glucuronosyltransferase 1-60101
Substance-K receptor0202
UDP-glucuronosyltransferase 1A40101
Cholecystokinin receptor type A0202
Melanocortin receptor 50202
UDP-glucuronosyltransferase 2B10 0101
Bcl-2-like protein 10101
Tyrosine-protein kinase Mer0101
Beta-tubulin 0101
Tubulin beta-2B chain0013
Similar to alpha-tubulin isoform 1 0013
Similar to alpha-tubulin isoform 1 0002
Solute carrier organic anion transporter family member 1B30405
Solute carrier organic anion transporter family member 1B10405
Beta-lactamase 0001
Beta-lactamase0001
Beta-lactamase0001
Beta-lactamase 10001
Beta-lactamase OXA-100001
Beta-lactamase0001
Guanine nucleotide-binding protein G1001
Beta-lactamase0001
Beta-lactamase 0002
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Glucocorticoid receptor04211
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glycine receptor subunit alpha-10404
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Androgen receptor0101
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Histamine H1 receptor0112
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Estrogen receptor beta0202
thioredoxin glutathione reductase1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
15-lipoxygenase, partial1001
Microtubule-associated protein tau2002
DNA-directed RNA polymerase subunit beta0101
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Solute carrier organic anion transporter family member 1A40101
Solute carrier organic anion transporter family member 2B1 0202
NH(3)-dependent NAD(+) synthetase0202
Polyunsaturated fatty acid lipoxygenase ALOX150101
Cytochrome P450 2B60011
Arylacetamide deacetylase0102
Caspase-10101
Solute carrier organic anion transporter family member 1A10101
Solute carrier organic anion transporter family member 1A20101
Glutathione S-transferase omega-10101
DNA-directed RNA polymerase subunit beta0101
cytochrome P450 2D6 isoform 11001
transcriptional regulator ERG isoform 31001
Solute carrier family 22 member 20101
5-hydroxytryptamine receptor 40202
Albumin0011
5-hydroxytryptamine receptor 1A0123
5-hydroxytryptamine receptor 2C0202
Angiotensin-converting enzyme0202
5-hydroxytryptamine receptor 2A0404
Alpha-1B adrenergic receptor0202
Beta-1 adrenergic receptor0101
D0101
D(3) dopamine receptor0101
5-hydroxytryptamine receptor 1A0202
Alpha-2B adrenergic receptor0202
D(1A) dopamine receptor0202
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0202
Glycine receptor subunit alpha-10011
Alpha-1D adrenergic receptor0202
Sodium-dependent dopamine transporter0101
Histamine H2 receptor0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
5-hydroxytryptamine receptor 1B0202
5-hydroxytryptamine receptor 2B0303
Sodium-dependent serotonin transporter0101
5-hydroxytryptamine receptor 7 0101
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
Alpha-1A adrenergic receptor0202
5-hydroxytryptamine receptor 2A0101
Alpha-1B adrenergic receptor0101
5-hydroxytryptamine receptor 2B0202
Alpha-1A adrenergic receptor0202
5-hydroxytryptamine receptor 60101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
D(2) dopamine receptor0101
D(2) dopamine receptor0202
5-hydroxytryptamine receptor 2B0101
Sodium channel protein type 5 subunit alpha0101
Transporter0101
5-hydroxytryptamine receptor 1A0101
Nuclear receptor subfamily 3 group C member 3 0202
Multidrug and toxin extrusion protein 20101
Transporter0202
Histamine H3 receptor0101
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
exodeoxyribonuclease V subunit RecD0101
exodeoxyribonuclease V subunit RecB0101
exodeoxyribonuclease V subunit RecC0101
ATP-dependent 6-phosphofructokinase0101
Dihydropteroate synthase0101
Dihydrofolate reductase0304
Protease 0112
Chain A, Dihydrofolate Reductase0011
Chain A, Dihydrofolate reductase0101
Chain A, dihydrofolate reductase (DHFR)0101
Chain A, Dihydrofolate reductase0101
Chain A, Dihydrofolate reductase0101
endonuclease IV1001
dopamine D1 receptor1001
NFKB1 protein, partial1001
Dihydrofolate reductase 0102
Dihydrofolate reductase0202
Dihydrofolate reductase0101
Dihydrofolate reductase 0101
Dihydrofolate reductase0202
Dihydrofolate reductase0202
Dihydrofolate reductase type 10102
Dihydrofolate reductase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase0101
Dihydrofolate reductase0202
Thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase type 1 from Tn40030101
Dipeptidyl peptidase 40101
Dihydrofolate reductase0101
Dipeptidyl peptidase 40101
Metabotropic glutamate receptor 50101
Dihydrofolate reductase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0102
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Trace amine-associated receptor 50011
Dihydrofolate reductase 0202
Dihydrofolate reductase 0101
Dihydrofolate reductase0102
Dihydrofolate reductase 0101
D-alanyl-D-alanine dipeptidase0101
twin arginine protein translocation system - TatA protein0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]