Page last updated: 2024-09-27

Atresia, Pulmonary

A congenital heart defect characterized by the narrowing or complete absence of the opening between the RIGHT VENTRICLE and the PULMONARY ARTERY. Lacking a normal PULMONARY VALVE, unoxygenated blood in the right ventricle can not be effectively pumped into the lung for oxygenation. Clinical features include rapid breathing, CYANOSIS, right ventricle atrophy, and abnormal heart sounds (HEART MURMURS).

Synonyms(8)

Synonym
Atresias, Pulmonary
Pulmonary Atresia
Pulmonary Atresias
Atresia, Pulmonary Valve
Atresias, Pulmonary Valve
Atresia, Pulmonary
Pulmonary Valve Atresia
Pulmonary Valve Atresias

Research Excerpts

Treatment

ExcerptReference
"In patients with pulmonary atresia with intact ventricular septum (PAIVS), biventricular repair is considered to be the optimal treatment option in the absence of significant right ventricular (RV) hypoplasia."( Blom, NA; Groenink, M; Hazekamp, MG; Luijnenburg, S; Mulder, BJ; Romeih, S; Spijkerboer, AM; van der Plas, MN, 2012)

Research

Studies (86)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's13 (15.12)12.5806
2000's29 (33.72)18.1394
2010's40 (46.51)28.8240
2020's4 (4.65)9.53
DrugIndicatedRelationship StrengthStudiesTrials
lactic acid0low10
aspirin0low20
fentanyl0low20
halothane0low10
hydroxyurea0low10
lidocaine0low10
indomethacin0low10
iohexol0low20
iomeprol0low10
iopromide0low20
isoproterenol0low10
midazolam0low20
propranolol0low10
ticlopidine0low10
tranexamic acid0low10
ampicillin0low10
arginine0low10
methylmethacrylate0low10
betamethasone0low10
vancomycin0low10
win 184460low10
floxacillin0low10
chromium0low20
gadolinium0low30
magnesium sulfate0low10
dobutamine0medium21
clopidogrel0low10
iopamidol0low10
fluorodeoxyglucose f180low20
arbekacin0low10
cobalt0low20
bosentan anhydrous0low20
sulbactam0low10
technetium tc 99m pentetate0low10
ropivacaine0low10
pancuronium0low10
rocuronium0low10
dibekacin0low10
digoxin0low10
thiopental0low10
nitrogen dioxide0low10
dinoprostone0low10
alprostadil0low130
phenylephrine hydrochloride0low10
sirolimus0low30
dexmedetomidine0low10
cysteine0low10
3,3'-dioctadecylindocarbocyanine0low10
carbocyanines0low10
everolimus0low10
gadolinium dtpa0medium41
lu 2080750low10
technetium tc 99m sestamibi0low10
cardiovascular agents0low10
natriuretic peptide, brain0low10
dicumarol0low10
rome0low10
daptomycin0low10
vitamin b 120low10
exudates0low10
folic acid0low10
rifampin0low10
sildenafil citrate0low20

Protein Targets (928)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
TDP1 protein130013
AR protein220022
glucocorticoid receptor [Homo sapiens]150015
estrogen nuclear receptor alpha210021
peroxisome proliferator activated receptor gamma100010
ATP-binding cassette sub-family C member 3013013
Multidrug resistance-associated protein 4013016
Bile salt export pump024024
Cellular tumor antigen p53110011
Thromboxane-A synthase 0202
Prostaglandin E2 receptor EP3 subtype0303
Prostaglandin E2 receptor EP4 subtype0314
Prostaglandin E2 receptor EP1 subtype0303
Prostacyclin receptor0325
Nuclear receptor subfamily 4 group A member 20011
Solute carrier organic anion transporter family member 2A10002
Nuclear receptor subfamily 4 group A member 20011
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin E2 receptor EP2 subtype0314
Canalicular multispecific organic anion transporter 1012012
Solute carrier organic anion transporter family member 2A10002
Solute carrier organic anion transporter family member 2B10101
Solute carrier organic anion transporter family member 3A10001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE9009
Chain A, Mutant Al2 6e7p9g0011
Chain A, Beta-lactamase3003
Chain A, 2-oxoglutarate Oxygenase5005
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Chain A, Cruzipain6006
Beta-lactamase 0001
acid sphingomyelinase2002
GLS protein8008
GLI family zinc finger 3100010
apical membrane antigen 1, AMA11001
retinoic acid nuclear receptor alpha variant 19009
farnesoid X nuclear receptor8008
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Metallo-beta-lactamase VIM-11 0001
euchromatic histone-lysine N-methyltransferase 2140014
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0102
Metallo-beta-lactamase0001
Beta-lactamase 0001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
chromobox protein homolog 18008
thyroid hormone receptor beta isoform 27007
DNA polymerase beta2002
DNA polymerase eta isoform 11001
DNA polymerase iota isoform a (long)5005
geminin130013
DNA polymerase kappa isoform 14004
Carbonic anhydrase 10405
Carbonic anhydrase 20507
60 kDa heat shock protein, mitochondrial0303
Beta-lactamase OXA-70001
Solute carrier family 15 member 10303
Solute carrier family 15 member 10101
Spike glycoprotein7007
10 kDa heat shock protein, mitochondrial0303
Angiopoietin-1 receptor0011
Beta-lactamase 0102
Beta-lactamase 0102
Beta-lactamase 0102
Solute carrier family 15 member 20101
Thiosulfate sulfurtransferase0303
Metallo-beta-lactamase VIM-130001
Efflux transporter 0001
Beta-lactamase 0001
Beta-lactamase Toho-10001
Beta-lactamase 0001
Class D beta-lactamase0102
60 kDa chaperonin 0303
Metallo-beta-lactamase0001
Solute carrier family 15 member 20101
Beta-lactamase 0102
Beta-lactamase 0001
10 kDa chaperonin 0303
Metallo-b-lactamase 0002
Carbapenem-hydrolyzing beta-lactamase KPC0102
Histamine H3 receptor0001
Beta-lactamase class B VIM-2 0002
Beta-lactamase VIM-1 0001
ATP-dependent phosphofructokinase3003
peripheral myelin protein 229009
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
thioredoxin reductase9009
phosphopantetheinyl transferase4004
NFKB1 protein, partial2002
thyroid stimulating hormone receptor8008
alpha-galactosidase3003
cytochrome P450 2C19 precursor4004
flap endonuclease 12002
muscarinic acetylcholine receptor M13003
lethal factor (plasmid)3003
Cytochrome P450 3A40416
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0102
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 84004
aldehyde dehydrogenase 1 family, member A18008
hypothetical protein, conserved1001
cytochrome P450 family 3 subfamily A polypeptide 4120012
EWS/FLI fusion protein8008
estrogen-related nuclear receptor alpha130013
cytochrome P450 2D66006
glucocerebrosidase3003
peroxisome proliferator-activated receptor delta6006
Rac1 protein0011
IDH15005
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
Bloom syndrome protein isoform 13003
Prostaglandin-H2 D-isomerase0202
Solute carrier family 22 member 60202
Prostaglandin G/H synthase 1 0203
Prostaglandin G/H synthase 2 0203
Epidermal growth factor receptor0325
Fatty acid-binding protein, liver0101
Integrin beta-33104
Myeloperoxidase0101
Prostaglandin G/H synthase 10304
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb3104
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10303
Adenosine receptor A10202
Adenosine receptor A2a0202
Substance-P receptor0202
Prostaglandin G/H synthase 20415
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma3115
Ras-related protein Rab-2A0011
Gamma-aminobutyric acid receptor subunit alpha-154110
Prostaglandin G/H synthase 20303
Rho-associated protein kinase 20202
Nicotinate phosphoribosyltransferase0202
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Sigma non-opioid intracellular receptor 10819
Sigma non-opioid intracellular receptor 10112
pregnane X receptor1001
progesterone receptor7007
pregnane X nuclear receptor110011
vitamin D (1,25- dihydroxyvitamin D3) receptor100010
aryl hydrocarbon receptor3003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a6006
nuclear receptor subfamily 1, group I, member 23003
thyroid hormone receptor beta isoform a3003
nuclear factor erythroid 2-related factor 2 isoform 23003
galanin receptor type 30101
nuclear factor erythroid 2-related factor 2 isoform 1110011
Voltage-dependent calcium channel gamma-2 subunit5005
Glucocorticoid receptor0202
Glycine receptor subunit alpha-10202
Glutamate receptor 25005
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
ORF730011
RAR-related orphan receptor gamma9009
estrogen receptor 2 (ER beta)7007
G5005
activating transcription factor 67007
v-jun sarcoma virus 17 oncogene homolog (avian)6006
vitamin D3 receptor isoform VDRA6006
heat shock protein beta-14004
nuclear receptor ROR-gamma isoform 15005
Bile salt export pump0808
Nuclear receptor subfamily 1 group I member 20055
Interferon beta6006
HLA class I histocompatibility antigen, B alpha chain 5005
Endothelin receptor type B0213
Endothelin receptor type B0314
Endothelin-1 receptor0415
Endothelin-1 receptor0224
Endothelin receptor type B0011
Deoxyhypusine synthase0101
Sodium/bile acid cotransporter0202
Endothelin-1 receptor0101
Inositol hexakisphosphate kinase 15005
cytochrome P450 2C9, partial5005
nonstructural protein 11001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
Cytochrome P450 2C80303
Cytochrome P450 2B60314
Liver carboxylesterase 10001
Sodium-dependent serotonin transporter0606
Cytochrome P450 2C190505
Rap guanine nucleotide exchange factor 41001
P2Y purinoceptor 120101
Alpha-1B adrenergic receptor 0011
cytochrome P450 2D6 isoform 13003
cellular tumor antigen p53 isoform a4004
cytochrome P450 2C9 precursor3003
cytochrome P450 3A4 isoform 15005
Gamma-aminobutyric acid receptor subunit pi5319
Alpha-2A adrenergic receptor0539
Gamma-aminobutyric acid receptor subunit beta-15319
Alpha-1B adrenergic receptor0516
Alpha-1A adrenergic receptor0011
Gamma-aminobutyric acid receptor subunit delta5319
Gamma-aminobutyric acid receptor subunit gamma-25319
Alpha-2C adrenergic receptor0438
Alpha-2B adrenergic receptor0415
Gamma-aminobutyric acid receptor subunit alpha-55319
Gamma-aminobutyric acid receptor subunit alpha-35319
Alpha-2C adrenergic receptor0415
Alpha-2A adrenergic receptor0415
Gamma-aminobutyric acid receptor subunit gamma-15319
Gamma-aminobutyric acid receptor subunit alpha-25319
Alpha-1D adrenergic receptor0516
Alpha-1D adrenergic receptor0326
Gamma-aminobutyric acid receptor subunit alpha-45319
Gamma-aminobutyric acid receptor subunit gamma-35319
Gamma-aminobutyric acid receptor subunit alpha-65319
Alpha-1A adrenergic receptor0516
Histamine H2 receptor4015
Gamma-aminobutyric acid receptor subunit beta-35319
Gamma-aminobutyric acid receptor subunit beta-25319
GABA theta subunit5319
Gamma-aminobutyric acid receptor subunit epsilon5319
Luciferase4004
hypoxia-inducible factor 1 alpha subunit2002
USP1 protein, partial7007
nuclear receptor subfamily 1, group I, member 36006
Histone H2A.x4004
potassium voltage-gated channel subfamily H member 2 isoform d4004
lamin isoform A-delta10120012
NAD0101
Cholinesterase0101
Urease0101
Cytochrome P450 2C9 0505
NAD0102
Mitogen-activated protein kinase 10123
ATP phosphoribosyltransferase0101
Proprotein convertase subtilisin/kexin type 70101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Integrase 0101
G-protein coupled receptor 350112
PAX80001
SMAD family member 23003
ATAD5 protein, partial3003
PPM1D protein1001
SMAD family member 33003
STAT3, partial0101
thioredoxin glutathione reductase1001
Smad32002
regulator of G-protein signaling 43003
retinoid X nuclear receptor alpha6006
67.9K protein3003
thyroid stimulating hormone receptor6006
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
NPC intracellular cholesterol transporter 1 precursor1001
tumor necrosis factor1001
ras-related protein Rab-9A2002
signal transducer and activator of transcription 1-alpha/beta isoform alpha0101
Solute carrier organic anion transporter family member 1A40203
Sodium/potassium-transporting ATPase subunit alpha-1 0202
Sodium/potassium-transporting ATPase subunit beta-10202
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit alpha-3 0101
ATP-dependent translocase ABCB10202
Sodium/potassium-transporting ATPase subunit beta-1 0101
ATP-dependent translocase ABCB10708
Replicase polyprotein 1ab0202
Sodium/potassium-transporting ATPase subunit alpha-30101
Sodium/potassium-transporting ATPase subunit beta-20101
ATP-dependent translocase ABCB10202
Sodium/potassium-transporting ATPase subunit alpha-20202
Sodium/potassium-transporting ATPase subunit alpha-10101
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit gamma0101
Sodium/potassium-transporting ATPase subunit alpha-40101
Sodium/potassium-transporting ATPase subunit alpha-40101
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 4C10001
ATPase family AAA domain-containing protein 52002
Ataxin-24004
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1B30506
Solute carrier organic anion transporter family member 1B10607
prostaglandin E2 receptor EP2 subtype1001
mitogen-activated protein kinase 12002
Solute carrier family 22 member 20001
Solute carrier family 22 member 1 0405
Solute carrier organic anion transporter family member 1A50001
Prostaglandin E2 receptor EP1 subtype0213
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin F2-alpha receptor0011
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP3 subtype0213
Prostaglandin E2 receptor EP2 subtype0213
Solute carrier family 22 member 60102
Solute carrier family 22 member 70002
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 80102
Solute carrier family 22 member 70001
Solute carrier family 22 member 110001
Solute carrier organic anion transporter family member 1B20001
Solute carrier family 22 member 70001
dopamine D1 receptor1001
glp-1 receptor, partial5005
Fumarate hydratase2002
GALC protein2002
polyprotein2002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
D(1A) dopamine receptor2002
mu-type opioid receptor isoform MOR-10022
huntingtin isoform 21001
5-hydroxytryptamine receptor 2A0022
Carbonic anhydrase 120102
Tyrosine-protein kinase Lck0123
Tyrosine-protein kinase Fyn0123
Carbonic anhydrase 30102
Beta-2 adrenergic receptor06310
Aldo-keto reductase family 1 member B10202
Beta-1 adrenergic receptor0628
Polyunsaturated fatty acid lipoxygenase ALOX150303
POU domain, class 2, transcription factor 10001
Alpha-2B adrenergic receptor0416
Carbonic anhydrase 40203
Carbonic anhydrase 60102
Sodium-dependent noradrenaline transporter 0202
Carbonic anhydrase 5A, mitochondrial0203
D(3) dopamine receptor0404
Carbonic anhydrase 70102
Sodium-dependent dopamine transporter 0202
Carbonic anhydrase 90204
Carbonic anhydrase 130101
Carbonic anhydrase 150101
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0102
Bone morphogenetic protein receptor type-1B0022
Cell division cycle 7-related protein kinase0022
Serine/threonine-protein kinase PLK40022
ATP-dependent RNA helicase DDX3X0022
Pyridoxal kinase0022
Citron Rho-interacting kinase0022
Serine/threonine-protein kinase Chk10022
Aurora kinase A0022
Cyclin-G-associated kinase0022
Ephrin type-B receptor 60022
Peroxisomal acyl-coenzyme A oxidase 30022
Receptor-interacting serine/threonine-protein kinase 20022
Mitotic checkpoint serine/threonine-protein kinase BUB10022
Dynamin-like 120 kDa protein, mitochondrial0022
Eukaryotic translation initiation factor 5B0022
Rho-associated protein kinase 20022
Serine/threonine-protein kinase ULK10022
Serine/threonine-protein kinase/endoribonuclease IRE10022
Ribosomal protein S6 kinase alpha-50022
U5 small nuclear ribonucleoprotein 200 kDa helicase0022
Ribosomal protein S6 kinase alpha-40022
Serine/threonine-protein kinase 160022
Serine/threonine-protein kinase 100022
Serine/threonine-protein kinase D30022
Structural maintenance of chromosomes protein 20022
Mitogen-activated protein kinase kinase kinase 60022
Mitogen-activated protein kinase kinase kinase kinase 40022
Serine/threonine-protein kinase LATS10022
Serine/threonine-protein kinase PAK 40022
Tyrosine-protein kinase ABL10022
High affinity nerve growth factor receptor0022
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20022
Protein kinase C beta type0022
Insulin receptor0022
Cyclin-dependent kinase 10022
Glycogen phosphorylase, liver form0022
Tyrosine-protein kinase Fes/Fps0022
Adenine phosphoribosyltransferase0022
Tyrosine-protein kinase Yes0022
Tyrosine-protein kinase Lyn0022
Proto-oncogene tyrosine-protein kinase receptor Ret0022
Insulin-like growth factor 1 receptor0022
Signal recognition particle receptor subunit alpha0022
Cytochrome c1, heme protein, mitochondrial0022
Hepatocyte growth factor receptor0022
Tyrosine-protein kinase HCK0022
Platelet-derived growth factor receptor beta0022
Tyrosine-protein kinase Fgr0022
Serine/threonine-protein kinase A-Raf0022
Glycogen phosphorylase, brain form0022
Breakpoint cluster region protein0022
Serine/threonine-protein kinase pim-10022
Fibroblast growth factor receptor 10022
DNA topoisomerase 2-alpha0022
Cyclin-dependent kinase 40022
ADP/ATP translocase 30022
Inosine-5'-monophosphate dehydrogenase 20022
Proto-oncogene tyrosine-protein kinase Src0022
cAMP-dependent protein kinase type II-alpha regulatory subunit0022
Serine/threonine-protein kinase B-raf0022
Potassium voltage-gated channel subfamily E member 10202
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0022
Ribosyldihydronicotinamide dehydrogenase [quinone]0022
Tyrosine-protein kinase Fer0022
Protein kinase C alpha type0022
cAMP-dependent protein kinase catalytic subunit alpha0022
General transcription and DNA repair factor IIH helicase subunit XPD0022
Casein kinase II subunit alpha'0022
Ras-related protein Rab-6A0022
Ephrin type-A receptor 10022
Multifunctional protein ADE20022
cAMP-dependent protein kinase catalytic subunit gamma0011
cAMP-dependent protein kinase catalytic subunit beta0022
Ferrochelatase, mitochondrial0022
Ribosomal protein S6 kinase beta-10022
Tyrosine-protein kinase JAK10022
Cyclin-dependent kinase 20022
Beta-adrenergic receptor kinase 10033
Probable ATP-dependent RNA helicase DDX60022
Mitogen-activated protein kinase 3 0022
MAP/microtubule affinity-regulating kinase 30022
Deoxycytidine kinase0022
Ephrin type-A receptor 20022
Ephrin type-B receptor 20022
Non-receptor tyrosine-protein kinase TYK20022
UMP-CMP kinase 0022
Phosphatidylethanolamine-binding protein 10022
Wee1-like protein kinase0022
Heme oxygenase 20022
S-adenosylmethionine synthase isoform type-20022
DnaJ homolog subfamily A member 10022
RAC-alpha serine/threonine-protein kinase0022
RAC-beta serine/threonine-protein kinase0022
Dual specificity protein kinase TTK0022
DNA replication licensing factor MCM40022
Myosin-100022
Dual specificity mitogen-activated protein kinase kinase 20022
Receptor-type tyrosine-protein kinase FLT30022
Bone morphogenetic protein receptor type-1A0022
Activin receptor type-1B0022
TGF-beta receptor type-10022
TGF-beta receptor type-20022
Electron transfer flavoprotein subunit beta0022
Tyrosine-protein kinase CSK0022
Glycine--tRNA ligase0022
Protein kinase C iota type0022
Exosome RNA helicase MTR40022
Serine/threonine-protein kinase mTOR0224
Tyrosine-protein kinase Tec0022
Tyrosine-protein kinase ABL20022
Tyrosine-protein kinase FRK0022
G protein-coupled receptor kinase 60022
Tyrosine-protein kinase SYK0022
26S proteasome regulatory subunit 6B0022
Mitogen-activated protein kinase 80022
Mitogen-activated protein kinase 90022
Dual specificity mitogen-activated protein kinase kinase 30022
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0022
Casein kinase I isoform alpha0022
Casein kinase I isoform delta0022
MAP kinase-activated protein kinase 20022
Elongation factor Tu, mitochondrial0022
Choline-phosphate cytidylyltransferase A0022
Cysteine--tRNA ligase, cytoplasmic0022
Casein kinase I isoform epsilon0022
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0022
Dual specificity protein kinase CLK10022
Dual specificity protein kinase CLK20022
Dual specificity protein kinase CLK30022
Glycogen synthase kinase-3 alpha0022
Glycogen synthase kinase-3 beta0022
Cyclin-dependent kinase 70022
Cyclin-dependent kinase 90022
Ras-related protein Rab-27A0022
Interleukin-1 receptor-associated kinase 10022
Potassium voltage-gated channel subfamily KQT member 10202
Ribosomal protein S6 kinase alpha-30022
Serine/threonine-protein kinase Nek20022
Serine/threonine-protein kinase Nek30022
Dual specificity mitogen-activated protein kinase kinase 60022
Serine/threonine-protein kinase PLK10022
LIM domain kinase 10022
LIM domain kinase 20022
Mitogen-activated protein kinase 100022
Tyrosine--tRNA ligase, cytoplasmic0022
5'-AMP-activated protein kinase subunit gamma-10022
Ephrin type-B receptor 30022
Ephrin type-A receptor 50022
Ephrin type-B receptor 40022
Ephrin type-A receptor 40022
Adenylate kinase 2, mitochondrial0022
Adenosine kinase0022
Ras-related protein Rab-100022
Actin-related protein 30022
Actin-related protein 20022
GTP-binding nuclear protein Ran0022
Casein kinase I isoform gamma-20022
Cyclin-dependent kinase 30011
Cyclin-dependent kinase 60022
Cyclin-dependent-like kinase 5 0022
Cyclin-dependent kinase 160022
Cyclin-dependent kinase 170022
ATP-dependent 6-phosphofructokinase, platelet type0022
Dual specificity mitogen-activated protein kinase kinase 10022
DNA topoisomerase 2-beta0022
Protein kinase C theta type0022
Activin receptor type-10022
Macrophage-stimulating protein receptor0022
Focal adhesion kinase 10022
Protein kinase C delta type0022
Tyrosine-protein kinase BTK0022
Activated CDC42 kinase 10022
Epithelial discoidin domain-containing receptor 10022
Potassium voltage-gated channel subfamily H member 20606
Mitogen-activated protein kinase kinase kinase kinase 20022
Serine/threonine-protein kinase 40022
5'-AMP-activated protein kinase catalytic subunit alpha-10022
Dual specificity mitogen-activated protein kinase kinase 50022
Mitogen-activated protein kinase 70022
Serine/threonine-protein kinase PAK 20022
Serine/threonine-protein kinase 30022
Mitogen-activated protein kinase kinase kinase 10022
Integrin-linked protein kinase0022
Rho-associated protein kinase 10022
Non-receptor tyrosine-protein kinase TNK10022
Calcium/calmodulin-dependent protein kinase type II subunit gamma0022
Calcium/calmodulin-dependent protein kinase type II subunit delta0022
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0022
Activin receptor type-2B0022
Bone morphogenetic protein receptor type-20022
Protein-tyrosine kinase 60022
cGMP-dependent protein kinase 1 0022
Cyclin-dependent kinase 130022
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0022
Protein-tyrosine kinase 2-beta0022
Sodium channel protein type 5 subunit alpha0404
Maternal embryonic leucine zipper kinase0022
Structural maintenance of chromosomes protein 1A0022
Chromodomain-helicase-DNA-binding protein 40022
Peroxisomal acyl-coenzyme A oxidase 10022
Ephrin type-A receptor 70011
Delta(24)-sterol reductase0022
Ribosomal protein S6 kinase alpha-10022
Dual specificity testis-specific protein kinase 10022
Myosin light chain kinase, smooth muscle0022
Mitogen-activated protein kinase 110022
Serine/threonine-protein kinase STK110022
Serine/threonine-protein kinase N10022
Serine/threonine-protein kinase N20022
Mitogen-activated protein kinase 140022
Calcium/calmodulin-dependent protein kinase type IV0022
Mitogen-activated protein kinase kinase kinase 110022
Discoidin domain-containing receptor 20022
AP2-associated protein kinase 10022
Myosin light chain kinase 30022
Putative heat shock protein HSP 90-beta 20022
Serine/threonine-protein kinase MRCK alpha0022
Serine/threonine-protein kinase MRCK gamma0022
Acyl-CoA dehydrogenase family member 100022
Serine/threonine-protein kinase N30022
Serine/threonine-protein kinase ULK30022
Uncharacterized protein FLJ452520022
Acyl-CoA dehydrogenase family member 110022
Serine/threonine-protein kinase/endoribonuclease IRE20022
Serine/threonine-protein kinase MARK20022
ATP-dependent RNA helicase DHX300022
Serine/threonine-protein kinase TAO10022
STE20-related kinase adapter protein alpha0022
Myosin-140022
AarF domain-containing protein kinase 10022
ATP-dependent RNA helicase DDX420011
Mitogen-activated protein kinase kinase kinase kinase 30022
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0011
Regulatory-associated protein of mTOR0202
Atypical kinase COQ8A, mitochondrial0022
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0022
Mitogen-activated protein kinase 150022
Serine/threonine-protein kinase Nek90022
Serine/threonine-protein kinase Nek70011
ATP-dependent RNA helicase DDX10022
Mitogen-activated protein kinase kinase kinase kinase 10022
Aurora kinase B0022
MAP/microtubule affinity-regulating kinase 40022
Serine/threonine-protein kinase Nek10022
PAS domain-containing serine/threonine-protein kinase0022
Calcium/calmodulin-dependent protein kinase kinase 20022
EKC/KEOPS complex subunit TP53RK0022
Dual specificity testis-specific protein kinase 20022
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0022
Mitogen-activated protein kinase kinase kinase 50022
Mitogen-activated protein kinase kinase kinase 30022
Eukaryotic translation initiation factor 2-alpha kinase 10022
Target of rapamycin complex subunit LST80202
Nucleolar GTP-binding protein 10022
Serine/threonine-protein kinase D20022
NUAK family SNF1-like kinase 20011
RNA cytidine acetyltransferase0022
Serine/threonine-protein kinase SIK20022
STE20-like serine/threonine-protein kinase 0022
Serine/threonine-protein kinase TAO30022
dCTP pyrophosphatase 10022
Dual specificity protein kinase CLK40022
Casein kinase I isoform gamma-10022
Phenylalanine--tRNA ligase beta subunit0022
BMP-2-inducible protein kinase0022
Obg-like ATPase 10022
Midasin0022
Interleukin-1 receptor-associated kinase 40022
Mitogen-activated protein kinase kinase kinase 200022
Cyclin-dependent kinase 120022
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Serine/threonine-protein kinase 260022
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0022
Serine/threonine-protein kinase NLK0022
5'-AMP-activated protein kinase subunit gamma-20022
Serine/threonine-protein kinase TBK10022
Septin-90022
Potassium voltage-gated channel subfamily D member 30202
Ribosomal protein S6 kinase alpha-60022
TRAF2 and NCK-interacting protein kinase0022
Serine/threonine-protein kinase TAO20022
Long-chain-fatty-acid--CoA ligase 50011
RAC-gamma serine/threonine-protein kinase0022
Serine/threonine-protein kinase SIK30022
Mitogen-activated protein kinase kinase kinase 20022
Thyroid hormone receptor-associated protein 30022
Mitogen-activated protein kinase kinase kinase kinase 50022
Receptor-interacting serine/threonine-protein kinase 30022
Serine/threonine-protein kinase MRCK beta0022
Interleukin-1 receptor-associated kinase 30022
Casein kinase I isoform gamma-30022
Mitogen-activated protein kinase kinase kinase 40022
D(2) dopamine receptor0314
Amine oxidase [flavin-containing] A0101
D(4) dopamine receptor0202
Amine oxidase [flavin-containing] B0101
Delta-type opioid receptor0202
Delta-type opioid receptor0202
Mu-type opioid receptor0213
Kappa-type opioid receptor0101
Histamine H1 receptor0101
Mu-type opioid receptor0325
Delta-type opioid receptor0314
Kappa-type opioid receptor0202
Kappa-type opioid receptor0314
Mu-type opioid receptor0101
Mu-type opioid receptor0202
Sigma non-opioid intracellular receptor 10202
Chain A, Dihydrofolate reductase0011
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
Chain A, Ferritin light chain3003
lysosomal alpha-glucosidase preproprotein2002
Thymidylate synthase0202
Thymidylate synthase0101
Dihydrofolate reductase0011
Aldo-keto reductase family 1 member B10202
Alpha-synuclein2103
Folylpolyglutamate synthase, mitochondrial0001
Solute carrier organic anion transporter family member 1A30202
Folylpolyglutamate synthase, mitochondrial0001
Multidrug resistance associated protein0001
Albumin0246
Voltage-dependent L-type calcium channel subunit alpha-1C0303
acetylcholinesterase3003
peripheral myelin protein 22 isoform 12002
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Stromelysin-10011
Gamma-aminobutyric acid receptor subunit alpha-10101
Urease subunit alpha0101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Ribonucleoside-diphosphate reductase large subunit0101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Urease subunit beta0101
Gamma-aminobutyric acid receptor subunit epsilon0101
Inositol monophosphatase 11001
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit theta0101
Chain A, membrane-associated prostaglandin E synthase-20101
Microtubule-associated protein tau4004
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
Parkin1001
bromodomain adjacent to zinc finger domain 2B1001
serine/threonine-protein kinase mTOR isoform 13003
M-phase phosphoprotein 81001
neuropeptide S receptor isoform A1001
Prostaglandin E synthase0101
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0404
Cytochrome c oxidase subunit 20101
Phospholipase A2, major isoenzyme0101
Procathepsin L0101
Neuronal acetylcholine receptor subunit alpha-41102
Interleukin-80101
Androgen receptor0011
Neuronal acetylcholine receptor subunit beta-21102
Polyunsaturated fatty acid 5-lipoxygenase0102
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Sodium-dependent dopamine transporter0101
Sodium- and chloride-dependent GABA transporter 10202
Serum paraoxonase/arylesterase 10101
Indoleamine 2,3-dioxygenase 10101
Caspase-10102
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Multidrug resistance-associated protein 1 0101
Bifunctional epoxide hydrolase 20101
Prostaglandin G/H synthase 2 0101
Peroxisome proliferator-activated receptor gamma0011
Aldo-keto reductase family 1 member C30202
Sodium- and chloride-dependent betaine transporter0202
C-X-C chemokine receptor type 30101
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G1001
Prostaglandin D2 receptor 0202
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10101
Prostaglandin G/H synthase 20102
Uracil nucleotide/cysteinyl leukotriene receptor0101
Sigma intracellular receptor 20101
Prostaglandin G/H synthase 1 0101
Multidrug and toxin extrusion protein 10202
Dehydrogenase/reductase SDR family member 90101
P2Y purinoceptor 120101
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
importin subunit beta-1 isoform 11001
snurportin-11001
GTP-binding nuclear protein Ran isoform 11001
NPYLR7B0011
Beta-1 adrenergic receptor 0125
beta-2 adrenergic receptor2002
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
Beta-2 adrenergic receptor0416
Beta-3 adrenergic receptor0325
Beta-1 adrenergic receptor0428
Beta-2 adrenergic receptor0011
D(1A) dopamine receptor0213
Beta-3 adrenergic receptor0011
Beta-3 adrenergic receptor0314
Vasopressin V1a receptor0011
Beta-1 adrenergic receptor0213
Alpha-1A adrenergic receptor0135
Alpha-1B adrenergic receptor0023
Glutamate receptor ionotropic, NMDA 1 0011
D(1A) dopamine receptor1001
Beta-2 adrenergic receptor0202
Taste receptor type 2 member 380011
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310011
Taste receptor type 2 member 450011
Taste receptor type 2 member 460011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600011
Oxytocin receptor0011
Glutamate receptor ionotropic, NMDA 2A 0011
Glutamate receptor ionotropic, NMDA 2B0011
Glutamate receptor ionotropic, NMDA 2C0011
Beta-2 adrenergic receptor 0112
Glutamate receptor ionotropic, NMDA 2D0011
Taste receptor type 2 member 420011
Beta-2 adrenergic receptor0135
Glutamate receptor ionotropic, NMDA 3B0011
Taste receptor type 2 member 160011
Taste receptor type 2 member 140011
Taste receptor type 2 member 130011
Taste receptor type 2 member 100011
Taste receptor type 2 member 90011
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40011
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
Glutamate receptor ionotropic, NMDA 3A0011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Potassium channel subfamily K member 30202
Potassium channel subfamily K member 20101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 4 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Sodium channel protein type 3 subunit alpha0101
Translocator protein0101
UDP-glucuronosyltransferase 2B70101
UDP-glucuronosyltransferase 1-60101
UDP-glucuronosyltransferase 1A1 0101
UDP-glucuronosyltransferase 1A40101
UDP-glucuronosyltransferase 2B10 0101
Atrial natriuretic peptide receptor 10101
arylsulfatase A2002
Vpr1001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
5-hydroxytryptamine receptor 40202
Cytochrome P450 1A20101
Muscarinic acetylcholine receptor M20112
5-hydroxytryptamine receptor 1A0101
Adenosine receptor A30112
Cytochrome P450 2D60202
Muscarinic acetylcholine receptor M10112
D(3) dopamine receptor0101
5-hydroxytryptamine receptor 1A0315
Muscarinic acetylcholine receptor M30112
Voltage-dependent L-type calcium channel subunit alpha-1C0101
5-hydroxytryptamine receptor 1B0213
5-hydroxytryptamine receptor 2A0213
5-hydroxytryptamine receptor 2C0213
5-hydroxytryptamine receptor 1B0202
Adenosine receptor A2a0112
Neuromedin-K receptor0011
Type-1 angiotensin II receptor0112
Cholecystokinin receptor type A0112
5-hydroxytryptamine receptor 70112
Vasopressin V1a receptor0112
5-hydroxytryptamine receptor 2B0213
5-hydroxytryptamine receptor 60213
5-hydroxytryptamine receptor 70101
Cytochrome P450 2J20202
Nuclear receptor subfamily 2 group E member 10022
15-lipoxygenase, partial1001
DNA-directed RNA polymerase subunit beta0101
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
NH(3)-dependent NAD(+) synthetase0101
Arylacetamide deacetylase0102
Solute carrier organic anion transporter family member 1A10101
Solute carrier organic anion transporter family member 1A20101
Glutathione S-transferase omega-10101
DNA gyrase subunit B0101
DNA gyrase subunit A0101
Enoyl-[acyl-carrier-protein] reductase [NADH]0101
DNA-directed RNA polymerase subunit beta0101
Lanosterol 14-alpha demethylase0101
Broad substrate specificity ATP-binding cassette transporter ABCG20202
Sphingosine kinase 20202
Sphingosine kinase 10101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Carbonic anhydrase 130001
Tyrosine-protein kinase JAK20011
Cyclin-dependent kinase-like 50011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Eukaryotic translation initiation factor 4E0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Serine/threonine-protein kinase receptor R30011
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Protein kinase C zeta type0011
Cyclin-dependent kinase 180011
Tyrosine-protein kinase Mer0011
Peptidyl-prolyl cis-trans isomerase FKBP50101
Uncharacterized aarF domain-containing protein kinase 50011
Programmed cell death protein 40011
MAP kinase-activated protein kinase 50011
Misshapen-like kinase 10011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase mTOR 0101
Isoleucine--tRNA ligase, mitochondrial0011
Serine/threonine-protein kinase ICK0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Serine/threonine-protein kinase 240011
Chain A, JmjC domain-containing histone demethylation protein 3A2002
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase0101
Beta-lactamase0101
Beta-lactamase0101
Beta-lactamase SHV-10101
Beta-lactamase OXA-10101
Beta-lactamase0101
Metallo-beta-lactamase type 20101
Angiotensin-converting enzyme0101
Beta-lactamase TEM0202
Beta-lactamase 0101
Beta-lactamase 0101
histone acetyltransferase KAT2A isoform 11001
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Fatty-acid amide hydrolase 10101
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
Disintegrin and metalloproteinase domain-containing protein 171001
Chain A, PLASMINOGEN0011
Chain A, PLASMINOGEN0011
Plasminogen0213
Urokinase-type plasminogen activator0101
Sodium-dependent serotonin transporter0101
D-alanyl-D-alanine dipeptidase0101
Transporter0101
Retinal dehydrogenase 20011
Retinal dehydrogenase 20101
Retinal dehydrogenase 10101
Aldehyde dehydrogenase, mitochondrial0101
Aldehyde dehydrogenase family 1 member A30101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]