Page last updated: 2024-09-28

Mediastinitis

Inflammation of the mediastinum, the area between the pleural sacs.

Synonyms(2)

Synonym
Mediastinum Inflammation
Mediastinitis

Research Excerpts

Overview

ExcerptReference
"Mediastinitis is a devastating complication following median sternotomy."( Finkbeiner, W; Glick, PL; Guglielmo, BJ; Turley, K; Winter, ME, 1990)
"Mediastinitis is one of severe and fatal complications after cardiac surgery, especially in the presence of a prosthetic graft."( Ih, S; Iwanaga, Y; Matsukane, H; Miyata, A; Nagayoshi, M; Nakao, S; Numata, Y; Ogata, Y; Taira, M, 1995)
"Postoperative mediastinitis is a serious complication of thoracic operations."( Aberg, B; Bitkover, CY; Gårdlund, B; Jacobsson, H; Larsson, SA, 1996)
"Postoperative mediastinitis is a rare but life-threatening complication after cardiac surgery."( Kosai, Y; Nagase, Y; Nakano, H; Sakamoto, T; Shibairi, M; Utsumi, K; Watanabe, H, 1998)
"Acute mediastinitis is an uncommon and potentially devastating infection."( Cattelan, AM; Concia, E; Faggian, F; Lanzafame, M; Lattuada, E; Trevenzoli, M, 2003)
"Fibrosing mediastinitis is an uncommon benign disorder, and its pathogenesis and management remain unclear."( Bruno, GL; El-Haddad, G; Lilien, DL; Makanjoula, AJ; Payne, DK; Takalkar, AM, 2007)
"Sclerosing mediastinitis is not a common condition in the thoracic cavity and is difficult to cure."( Inoue, M; Kawaguchi, M; Nishikawa, H; Nose, N; Takahashi, M; Zen, Y, 2007)
"Mediastinitis is a rare but serious postoperative complication of cardiac surgery that increases mortality rates, hospital length of stay, and medical costs."( Finley, PJ; Huckfeldt, R; Lowe, C; Mikkelson, D; Redmond, C; Robertson, J, 2008)
"Mediastinitis is a dreaded complication of cardiac surgical procedures."( Ceran, N; Gorur, R; Oncul, O; Sacar, M; Sacar, S; Turhan, V; Uzun, G; Yildiz, S, 2009)
"Postoperative mediastinitis is one of the most worrisome complications after heart surgery."( Blin, D; Chavanon, O; Costache, V; Gaudreau, G; Hacini, R; Houde, C; Rodière, M, 2010)
"Postoperative mediastinitis is a serious and potentially lethal complication from cardiac surgery."( Lee, JC; Raman, J; Song, DH, 2010)
"Sclerosing mediastinitis is a rare, benign disorder that is often indistinguishable from malignancy by conventional imaging techniques."( Iguchi, K; Inagaki, M; Ishikawa, S; Matsuoka, T; Onuki, T, 2011)
"Mediastinitis is a severe complication after cardiac surgery."( Beiras-Fernandez, A; Hagl, C; Heyn, J; Hinske, CL; Kur, F; Vogt, F; Weis, F; Weis, M, 2012)
"Fibrosing mediastinitis is rare."( Amitani, R; Ariyasu, R; Hanaoka, K; Inada, S; Konishi, Y; Nagano, H; Nakagawa, K; Nakamura, Y; Nishizaka, Y; Okamoto, N; Taki, M; Tsudo, M; Wakasa, T; Wakayama, T; Yoshida, M; Yoshimura, C, 2013)
"Mediastinitis is a serious complication after cardiac surgery."( Auvergne, L; Ben Ayed, I; Botterel, F; Caballero, MJ; Dhonneur, G; Haouache, H; Hillion, ML; Mongardon, N; Vodovar, D, 2016)

Actions

ExcerptReference
"Post-sternotomy mediastinitis affects 1-3% of patients undergoing cardiac surgery and is lethal in 10-47% of these patients."( Aytacoglu, BN; Bayindir, I; Coskun, B; Dikmengil, M; Ersoz, G; Kose, N; Oguz, I; Ozeren, M; Sucu, N; Tamer, L, 2006)

Treatment

ExcerptReference
"Twenty-three cases of mediastinitis after cardiac surgery in children were treated by us between 1973 and 1976."( Barois, A; Bourda, JL; Chapuis, C; Combes, A; Goulon, M; Grosbuis, S; Simon, N, 1978)
"19 critically ill adults with acute mediastinitis after cardiac surgery were treated with granulated sugar, either directly (11 patients) or after failure of continuous irrigation (8 patients)."( Chastre, J; Domart, Y; Fagon, JY; Gibert, C; Pierre, J; Trouillet, JL, 1985)
"We describe a 34-month-old patient with mediastinitis after median sternotomy who was treated with continuous povidone-iodine irrigation and who absorbed toxic quantities of iodine (total serum iodine, 9,375 micrograms/dl; normal range, 4."( Glick, PL; Guglielmo, BJ; Tranbaugh, RF; Turley, K, 1985)
"MRSA mediastinitis was successfully treated by continuous closed irrigation with 0."( Ishizawa, A; Isoda, T; Miyaji, K; Nishimura, K; Sekiguchi, A; Shimada, M, 1993)
"We conclude that in patients with mediastinitis treated by insertion of a closed irrigation drainage, the retrosternally irrigated cavity seems to become smaller over the therapeutic course of treatment."( Hetzer, R; Krabatsch, T, 1999)
"We describe a case of suppurative mediastinitis secondary to a retropharyngeal abscess in a 19-month-old girl and discuss the pathophysiology, diagnosis, and treatment of this disease."( Grassi, MS; Katayama, DM; Sztajnbok, J; Troster, EJ, 1999)
"Combined treatment of acute mediastinitis, including cryoplasma-antienzymic complex use and indirect electrochemical blood plasma detoxication, promotes disappearance of microcirculation disorders, to earlier decreasing of endogenic intoxication, outcomes improvement."( Gurevich, IuIu; Semenov, VP; Serebriakov, EN; Tseĭmakh, EA; Tulopov, VA; Zaĭtsev, VA, 2000)
"A diagnosis of idiopathic fibrosing mediastinitis was made, and 40 mg/day of prednisolone was administered."( Aoki, S; Kanegae, F; Koarada, S; Nagasawa, K; Ohta, A; Onoue, H; Suzuki, N; Tada, Y; Ushiyama, O, 2002)
"Reported here is a case of mediastinitis caused by Aspergillus fumigatus and Staphylococcus epidermidis following a heart transplantation that was successfully treated with amphotericin B in combination with new antifungal drugs (caspofungin and voriconazole), antibiotics and superficial wound drainage."( Christmann, D; Eisenmann, B; Forestier, E; Hansman, Y; Lesens, O; Martinot, M; Remy, V, 2005)
"The prognosis of patients with mediastinitis crucially depends on (a) early diagnosis including computed tomography of the neck and thorax, (b) early radical surgical intervention, and (c) optimized pathogen-oriented antibiotic treatment."( Bartsch, MS; Schäfer, FK; von Bernstorff, W; Warnke, PH; Wiltfang, J, 2005)
"The management of mediastinitis involves directing appropriate antibacterial therapy against the potential bacterial pathogens."( Brook, I, 2006)
"We report a case of MRSA mediastinitis after replacement of the ascending aorta and the aortic valve successfully treated by continuous saline lavage and drainage, debridement, high-pressure irrigation, and gentian-violet application, and delayed omental-flap transposition."( Imaizumi, M; Kato, T; Matsuno, Y; Takagi, H; Umemoto, T, 2006)
"We report a case of mediastinitis successfully treated with autovaccine therapy, once conventional surgical and medical therapies had failed."( Brancaccio, G; De Vito, D; Rizzo, C; Rizzo, G, 2007)
"The treatment of postoperative mediastinitis is very important because of its high morbidity, mortality, and increased hospital stay and hospital costs."( Asan, A; Aytekin, FO; Baltalarli, A; Cevahir, N; Kaleli, I; Kavas, ST; Sacar, M; Sacar, S; Teke, Z; Turgut, H, 2008)
"Descending mediastinitis occurs as a complication of oropharyngeal or cervical infections and its delayed diagnosis and treatment are associated with high mortality."( Bourolias, CA; Karatzanis, AD; Kofteridis, DP; Mantadakis, E; Papazoglou, G; Samonis, G; Velegrakis, GA, 2008)

Research

Studies (310)

TimeframeStudies, This Condition (%)All Conditions %
pre-199060 (19.35)23.3326
1990's56 (18.06)12.5806
2000's95 (30.65)18.1394
2010's87 (28.06)28.8240
2020's12 (3.87)9.53
DrugIndicatedRelationship StrengthStudiesTrials
citric acid, anhydrous0low10
hydrochloric acid0low10
iodine0low50
phosphorylcholine0low10
pyrazinamide0low10
taurine0low10
acetaminophen0low10
albuterol0low10
diatrizoic acid0low20
azathioprine0low20
bromhexine0low10
bupivacaine0low20
carvedilol0low10
cefuroxime0medium21
chlorothiazide0low10
cifenline0low10
ciprofloxacin0low30
diethylcarbamazine0low10
pentetic acid0low10
fluconazole0low30
fluorouracil0low20
furosemide0low20
gentamicin0medium182
glafenine0low10
glutaral0low10
miltefosine0low10
hydrochlorothiazide0low10
hydroxychloroquine0low10
iohexol0low10
iopromide0low10
isoniazid0low10
2-propanol0low10
ketoconazole0low10
khellin0low10
mepivacaine0low10
metronidazole0low40
mianserin0low10
molsidomine0low10
nifedipine0low10
nitroglycerin0low10
omeprazole0low10
sulfadimethoxine0low10
sulfanilamide0low10
thioridazine0low10
triclosan0low10
prednisolone0low140
cephaloridine0low10
spironolactone0low20
prednisone0medium101
penicillin g0low60
chloramphenicol0low10
sucrose0low30
cephalothin0low10
kanamycin a0low10
phenylethyl alcohol0low10
methicillin0low30
cloxacillin0low10
methylene blue0low10
oxacillin0low10
ampicillin0low40
arginine0low10
phencyclidine0low10
methylprednisolone0low10
penicillin v0low20
penicillanic acid0low20
n-vinyl-2-pyrrolidinone0low40
framycetin0low10
diatrizoate meglumine0low10
nafcillin0low10
dexamethasone 21-phosphate0low10
nandrolone decanoate0low10
methysergide0low10
nandrolone0low10
dextropropoxyphene0low10
malondialdehyde0low20
gentian violet0low40
ethambutol0low10
durapatite0low10
thorium dioxide0low10
vancomycin0medium231
paraquat0low10
dicloxacillin0low10
streptomycin0low50
carbenicillin0low10
floxacillin0low10
silver0medium21
technetium0medium41
titanium0low100
barium sulfate0low50
ozone0low10
trolamine salicylate0low20
cephalexin0low10
taurolidine0low10
cefazolin0medium61
amoxicillin0low50
gallium citrate0low20
tobramycin0low20
amikacin0low10
cephradine0low10
cefmetazole0low10
cefonicid0low10
piperacillin0low20
fomesafen0low10
itraconazole0low50
iopamidol0low10
cephalosporin c0low100
xenon radioisotopes0low10
triazoles0low60
fluorodeoxyglucose f180low120
voriconazole0low100
oxazolidin-2-one0low60
mci 90380low10
imatinib mesylate0low10
tazobactam0low10
sulbactam0low30
carbapenems0low10
beta-lactams0low10
technetium tc 99m pentetate0low10
angiotensin ii0low10
tolvaptan0low10
cortisone0low10
trimethoprim, sulfamethoxazole drug combination0low10
povidone-iodine0low180
glycogen0low10
fibrin0low20
meropenem0low30
linezolid0low80
sultamicillin0low20
tacrolimus0low10
mupirocin0low30
clindamycin0low50
fosfomycin0medium21
cefamandole0low10
posaconazole0low10
l 743,8720low30
abt 4920low10
tamoxifen0low10
fusidic acid0low10
pica0low10
lithium0low10
telavancin0low10
vitamin k semiquinone radical0low10
amphotericin b0low120
clavulanic acid0low30
humulene0low10
caffeic acid phenethyl ester0low10
tranilast0low10
phenylephrine hydrochloride0low30
morphine0low10
barium0low10
gallium0low20
cefotaxime0low30
chlorhexidine0low40
amoxicillin-potassium clavulanate combination0low60
mocetinostat0low10
nystatin a10low10
technetium tc 99m exametazime0medium21
pituitrin0low10
rifamycins0low10
clove0low10
cellulose0low10
sodium hypochlorite0low20
ro13-99040medium61
piperacillin, tazobactam drug combination0low20
interleukin-80low10
colistin0low20
hydroxocobalamin0low10
chlortetracycline0low20
oxytetracycline, anhydrous0low10
minocycline0low30
piroxicam0low10
warfarin0low10
tigecycline0low30
calca protein, human0low50
daptomycin0low10
technetium tc 99m medronate0low10
thromboplastin0low10
levoleucovorin0low20
rifampin0low30
dacarbazine0low10
ceftobiprole medocaril0low10
eye0low10

Protein Targets (1,115)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
hypoxia-inducible factor 1 alpha subunit170017
RAR-related orphan receptor gamma340034
GLI family zinc finger 3410041
AR protein410041
aldehyde dehydrogenase 1 family, member A1270027
retinoic acid nuclear receptor alpha variant 1360036
retinoid X nuclear receptor alpha290029
estrogen nuclear receptor alpha630063
peroxisome proliferator-activated receptor delta250025
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a240024
activating transcription factor 6180018
v-jun sarcoma virus 17 oncogene homolog (avian)230023
Histone H2A.x160016
thyroid hormone receptor beta isoform a130013
heat shock protein beta-1150015
nuclear factor erythroid 2-related factor 2 isoform 1410041
lamin isoform A-delta10260026
Voltage-dependent calcium channel gamma-2 subunit190019
Glutamate receptor 2190019
G230023
Interferon beta290029
HLA class I histocompatibility antigen, B alpha chain 230023
Cytochrome P450 1A2010012
Cytochrome P450 3A4022127
Cytochrome P450 2D6011012
Cytochrome P450 2C9 020021
Cytochrome P450 2C19012014
Inositol hexakisphosphate kinase 1230023
cytochrome P450 2C9, partial230023
ATAD5 protein, partial130013
GLS protein200020
Microtubule-associated protein tau180019
Smad37007
thyroid stimulating hormone receptor130013
nuclear receptor subfamily 1, group I, member 3280028
progesterone receptor250025
EWS/FLI fusion protein240024
estrogen-related nuclear receptor alpha420042
peroxisome proliferator activated receptor gamma260026
aryl hydrocarbon receptor230023
chromobox protein homolog 1250025
thyroid hormone receptor beta isoform 2320032
peripheral myelin protein 22170017
cytochrome P450 3A4 isoform 1170017
Gamma-aminobutyric acid receptor subunit pi172020
ATP-binding cassette sub-family C member 3042042
Multidrug resistance-associated protein 4042043
Solute carrier family 22 member 6013013
Carbonic anhydrase 120405
UDP-glucuronosyltransferase 1A90001
Bile salt export pump017017
Bile salt export pump060060
Cytochrome P450 2B10001
Cytochrome P450 1A10001
Carbonic anhydrase 10709
Carbonic anhydrase 209213
Myoglobin0101
Cytochrome P450 1A10214
Prostaglandin G/H synthase 10202
Carbonic anhydrase 30404
Polyunsaturated fatty acid lipoxygenase ALOX150404
Gamma-aminobutyric acid receptor subunit beta-1172020
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta172020
Gamma-aminobutyric acid receptor subunit gamma-2172020
UDP-glucuronosyltransferase 1-60102
Gamma-aminobutyric acid receptor subunit alpha-5172020
Gamma-aminobutyric acid receptor subunit alpha-3172020
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0304
Carbonic anhydrase 40506
Prostaglandin G/H synthase 10505
Carbonic anhydrase 60607
Gamma-aminobutyric acid receptor subunit gamma-1172020
Gamma-aminobutyric acid receptor subunit alpha-2172020
Gamma-aminobutyric acid receptor subunit alpha-4172020
Gamma-aminobutyric acid receptor subunit gamma-3172020
Gamma-aminobutyric acid receptor subunit alpha-6172020
Carbonic anhydrase 5A, mitochondrial0608
Prostaglandin G/H synthase 20304
Carbonic anhydrase 70506
Nuclear receptor ROR-gamma100010
Cytochrome P450 2J20909
Gamma-aminobutyric acid receptor subunit alpha-1172020
Gamma-aminobutyric acid receptor subunit beta-3172020
Gamma-aminobutyric acid receptor subunit beta-2172020
Carbonic anhydrase 90719
GABA theta subunit172020
Canalicular multispecific organic anion transporter 1041041
Carbonic anhydrase 150202
Carbonic anhydrase 130506
Gamma-aminobutyric acid receptor subunit epsilon172020
Carbonic anhydrase 140405
Carbonic anhydrase 5B, mitochondrial0507
toxin B0001
glp-1 receptor, partial110011
thioredoxin reductase190019
regulator of G-protein signaling 4120012
NPYLR7B0011
arylsulfatase A180018
euchromatic histone-lysine N-methyltransferase 2330033
thyroid stimulating hormone receptor160016
flap endonuclease 1100010
Beta-2 adrenergic receptor0437
Beta-1 adrenergic receptor0437
60 kDa chaperonin0202
60 kDa heat shock protein, mitochondrial0505
Beta-3 adrenergic receptor0426
Delta-type opioid receptor0427
10 kDa heat shock protein, mitochondrial0505
Thiosulfate sulfurtransferase0505
Beta-2 adrenergic receptor 0013
60 kDa chaperonin 0505
10 kDa chaperonin 0505
Beta-2 adrenergic receptor0225
ATP-dependent phosphofructokinase180018
histone acetyltransferase KAT2A isoform 1100010
Aminoglycoside 3'-phosphotransferase 0002
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE230023
Chain A, Beta-lactamase8008
Chain A, 2-oxoglutarate Oxygenase180018
Beta-lactamase 0206
Beta-lactamase 0208
Beta-lactamase 0007
Beta-lactamase 03010
apical membrane antigen 1, AMA17007
Beta-lactamase 0005
peptidyl-prolyl cis-trans isomerase NIMA-interacting 17007
DNA polymerase eta isoform 16006
DNA polymerase iota isoform a (long)160016
urokinase-type plasminogen activator precursor7007
plasminogen precursor7007
urokinase plasminogen activator surface receptor precursor7007
DNA polymerase kappa isoform 1100010
Beta-lactamase SHV-10207
Beta-lactamase SHV-105013
Beta-lactamase03011
Kappa-type opioid receptor0208
Solute carrier family 15 member 1020020
Solute carrier family 15 member 10405
B2 metallo-beta-lactamase 0009
Solute carrier family 15 member 2012012
Beta-lactamase 0207
Beta-lactamase 0106
Solute carrier family 15 member 2013014
Beta-lactamase 0207
Beta-lactamase 0006
Chain A, HADH2 protein9009
Chain B, HADH2 protein9009
Chain A, Cruzipain100010
interleukin 89009
phosphopantetheinyl transferase180018
glucocorticoid receptor [Homo sapiens]390039
farnesoid X nuclear receptor240024
vitamin D (1,25- dihydroxyvitamin D3) receptor210021
tumor necrosis factor3003
vitamin D3 receptor isoform VDRA170017
Potassium voltage-gated channel subfamily H member 2018019
Aurora kinase B0202
Broad substrate specificity ATP-binding cassette transporter ABCG20909
Chain A, Mutant Al2 6e7p9g0011
Chain A, ATP-DEPENDENT DNA HELICASE Q15005
Beta-lactamase 0307
acid sphingomyelinase2002
Beta-lactamase 0208
Beta-lactamase 0108
Metallo-beta-lactamase type 20018
Metallo-beta-lactamase VIM-11 0006
Metallo-beta-lactamase VIM-20006
Beta-lactamase 0108
Metallo-beta-lactamase0006
Beta-lactamase 0208
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1120012
DNA polymerase beta4004
geminin420042
Beta-lactamase OXA-70006
Spike glycoprotein260228
Angiopoietin-1 receptor0011
Beta-lactamase 0206
Beta-lactamase 0206
Beta-lactamase 0206
Metallo-beta-lactamase VIM-130007
Efflux transporter 0105
Beta-lactamase 0107
Beta-lactamase Toho-10005
Beta-lactamase 0105
Class D beta-lactamase0308
Metallo-beta-lactamase0005
Beta-lactamase 0309
Beta-lactamase 0015
Metallo-b-lactamase 00013
Carbapenem-hydrolyzing beta-lactamase KPC05013
Histamine H3 receptor0006
Beta-lactamase class B VIM-2 00114
Beta-lactamase VIM-1 0007
glucocerebrosidase6006
Atrial natriuretic peptide receptor 30101
Type-1A angiotensin II receptor 0213
Type-1 angiotensin II receptor0011
Type-1B angiotensin II receptor0202
Type-1 angiotensin II receptor0224
Type-2 angiotensin II receptor0404
Type-2 angiotensin II receptor0202
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
NFKB1 protein, partial5005
alpha-galactosidase2002
cytochrome P450 2C19 precursor8008
muscarinic acetylcholine receptor M17007
lethal factor (plasmid)7007
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE140014
Chain A, Ferritin light chain100010
acetylcholinesterase170017
SMAD family member 2110011
Fumarate hydratase100010
SMAD family member 3110011
TDP1 protein360036
thioredoxin glutathione reductase7007
pregnane X nuclear receptor350035
polyprotein100010
P531001
IDH1150015
Bloom syndrome protein isoform 1100010
peripheral myelin protein 22 isoform 18008
hemoglobin subunit beta2002
cellular tumor antigen p53 isoform a6006
survival motor neuron protein isoform d130013
M-phase phosphoprotein 88008
muscleblind-like protein 1 isoform 19009
Cellular tumor antigen p53290029
ATPase family AAA domain-containing protein 5180018
Ataxin-2210021
Protein-arginine deiminase type-40909
Sodium-dependent serotonin transporter012012
Sigma non-opioid intracellular receptor 10909
Potassium channel subfamily K member 30202
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20123
Potassium channel subfamily K member 90101
Chain A, Putative fructose-1,6-bisphosphate aldolase110011
Chain A, JmjC domain-containing histone demethylation protein 3A120012
endonuclease IV6006
Nrf21001
15-lipoxygenase, partial5005
USP1 protein, partial230023
nonstructural protein 18008
67.9K protein9009
Parkin7007
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)4004
polyunsaturated fatty acid lipoxygenase ALOX124004
D(1A) dopamine receptor7007
importin subunit beta-1 isoform 16006
serine/threonine-protein kinase mTOR isoform 17007
snurportin-16006
nuclear receptor ROR-gamma isoform 1120012
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Polyunsaturated fatty acid lipoxygenase ALOX15B9009
Aldo-keto reductase family 1 member B100202
Epidermal growth factor receptor0505
Pancreatic triacylglycerol lipase0001
Transthyretin0123
Estrogen receptor08211
Receptor tyrosine-protein kinase erbB-20202
Amyloid-beta precursor protein1214
Tyrosine-protein kinase Lck0202
Tyrosine-protein kinase Fyn0404
Aldo-keto reductase family 1 member B1012012
Polyunsaturated fatty acid 5-lipoxygenase0303
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B10101
Polyunsaturated fatty acid lipoxygenase ALOX150101
Aldo-keto reductase family 1 member C40101
Sodium-dependent noradrenaline transporter 012113
Mitogen-activated protein kinase 10101
Alpha-synuclein6107
Aldo-keto reductase family 1 member C30101
Histamine H2 receptor121014
D(1A) dopamine receptor3003
Aldo-keto reductase family 1 member C2 0101
Aldo-keto reductase family 1 member C10101
TAR DNA-binding protein 439009
Integrase 0202
Dihydroxyacetone phosphate acyltransferase0002
bromodomain adjacent to zinc finger domain 2B110011
lysosomal alpha-glucosidase preproprotein3003
mitogen-activated protein kinase 1120012
histone-lysine N-methyltransferase 2A isoform 2 precursor5005
short transient receptor potential channel 6 isoform 10011
Toll-like receptor 40101
Solute carrier family 22 member 20202
Solute carrier family 22 member 1 0506
5-hydroxytryptamine receptor 4012012
ATP-dependent translocase ABCB1010111
Alpha-2A adrenergic receptor016117
Neuronal acetylcholine receptor subunit alpha-43003
Neuronal acetylcholine receptor subunit beta-23003
Angiotensin-converting enzyme0606
D(2) dopamine receptor012012
Alpha-2B adrenergic receptor015015
Alpha-2C adrenergic receptor0909
5-hydroxytryptamine receptor 1A012012
D(1A) dopamine receptor012012
Alpha-1D adrenergic receptor012012
5-hydroxytryptamine receptor 2A012012
5-hydroxytryptamine receptor 2C012012
5-hydroxytryptamine receptor 1B010010
D(3) dopamine receptor012012
5-hydroxytryptamine receptor 2B010010
5-hydroxytryptamine receptor 6012013
Potassium channel subfamily K member 100101
Sodium-dependent dopamine transporter 010010
Cytochrome P450 1B10202
Nuclear receptor subfamily 3 group C member 3 0606
Multidrug and toxin extrusion protein 10505
Solute carrier family 22 member 60909
Solute carrier family 22 member 70404
Solute carrier family 22 member 80707
Solute carrier family 22 member 110606
Solute carrier family 22 member 80708
Solute carrier family 22 member 70404
Luciferase170017
cytochrome P450 2D6200020
Solute carrier family 22 member 809011
Insulin-degrading enzyme0101
Beta-lactamase 0408
Beta-lactamase 0407
Metallo-beta-lactamase VIM-19 0005
Beta-lactamase 0308
Albumin0369
Beta-lactamase 0003
Beta-lactamase 0308
Metallo-beta-lactamase VIM-20006
BlaVIM-1 0005
Beta-lactamase 0003
Beta-lactamase 0207
Beta-lactamase 0002
potassium voltage-gated channel subfamily H member 2 isoform d110011
Beta-lactamase0002
Nuclear receptor subfamily 1 group I member 20044
Solute carrier family 22 member 50101
Beta-lactamase0306
Beta-lactamase04010
Beta-lactamase OXA-100002
Beta-lactamase0002
Beta-lactamase TEM08014
Beta-lactamase0103
Beta-lactamase 0004
Beta-lactamase 0004
Beta-lactamase IMP-1 0004
Beta-lactamase 0004
WRN2002
cytochrome P450 family 3 subfamily A polypeptide 4280028
DNA (cytosine-5)-methyltransferase 1 isoform b0101
serine/threonine-protein kinase PLK14004
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 10101
Beta-lactamase OXA-10305
Beta-lactamase 0104
phosphoglycerate kinase3003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a150015
streptokinase A precursor0077
30S ribosomal protein S60303
30S ribosomal protein S70303
50S ribosomal protein L150303
50S ribosomal protein L100303
50S ribosomal protein L110303
50S ribosomal protein L7/L120303
50S ribosomal protein L190303
50S ribosomal protein L10303
50S ribosomal protein L200303
50S ribosomal protein L270303
50S ribosomal protein L280303
50S ribosomal protein L290303
50S ribosomal protein L310303
50S ribosomal protein L31 type B0303
50S ribosomal protein L320303
50S ribosomal protein L330303
50S ribosomal protein L340303
50S ribosomal protein L350303
50S ribosomal protein L360303
30S ribosomal protein S100303
30S ribosomal protein S110303
30S ribosomal protein S120303
30S ribosomal protein S130303
30S ribosomal protein S160303
30S ribosomal protein S180303
30S ribosomal protein S190303
30S ribosomal protein S200303
30S ribosomal protein S20303
30S ribosomal protein S30303
30S ribosomal protein S40303
30S ribosomal protein S50303
30S ribosomal protein S80303
30S ribosomal protein S90303
50S ribosomal protein L130303
50S ribosomal protein L140303
50S ribosomal protein L160303
50S ribosomal protein L230303
30S ribosomal protein S150303
50S ribosomal protein L170303
50S ribosomal protein L210303
50S ribosomal protein L300303
50S ribosomal protein L60303
30S ribosomal protein S140303
30S ribosomal protein S170303
30S ribosomal protein S10303
50S ribosomal protein L180303
50S ribosomal protein L20303
50S ribosomal protein L30303
50S ribosomal protein L240303
50S ribosomal protein L40303
50S ribosomal protein L220303
50S ribosomal protein L50303
30S ribosomal protein S210303
50S ribosomal protein L250303
50S ribosomal protein L36 20303
Methionine--tRNA ligase, mitochondrial0011
Chain A, BCL-2-RELATED PROTEIN A10022
PAX80001
pregnane X receptor8008
caspase 7, apoptosis-related cysteine protease7007
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)9009
PINK12002
estrogen receptor 2 (ER beta)210021
heat shock protein 900022
caspase-37007
calcineurin A1, putative0011
cytochrome P450 2D6 isoform 16006
hepatocyte nuclear factor 4-alpha isoform 20202
cytochrome P450 2C9 precursor5005
perilipin-50303
perilipin-10303
nuclear factor erythroid 2-related factor 2 isoform 27007
transcriptional regulator ERG isoform 36006
huntingtin isoform 27007
ubiquitin-conjugating enzyme E2 N0202
nuclear factor NF-kappa-B p105 subunit isoform 12002
protein AF-9 isoform a0002
melanocortin receptor 40101
CAAX prenyl protease0001
bcl-2-related protein A10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0303
glycogen synthase kinase-3 alpha0001
hexokinase HKDC10101
DNA repair protein RAD52 homolog isoform a0003
bcl-2-like protein 11 isoform 10022
Synaptojanin-20101
Synaptojanin-10101
Solute carrier family 22 member 30101
Glutathione reductase, mitochondrial0406
Integrin beta-35005
72 kDa type IV collagenase0101
Integrin alpha-IIb5005
Matrix metalloproteinase-90303
Trypanothione reductase0101
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase0101
Multidrug and toxin extrusion protein 20101
Rap guanine nucleotide exchange factor 42002
Spermine oxidase0101
ORF730011
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
P2Y purinoceptor 120101
atrial natriuretic peptide receptor 2 precursor4004
Voltage-dependent L-type calcium channel subunit alpha-1F0808
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 4 subunit alpha0202
Sodium channel protein type 7 subunit alpha0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0808
Voltage-dependent L-type calcium channel subunit alpha-1S0808
Voltage-dependent L-type calcium channel subunit alpha-1C0809
Sodium channel protein type 5 subunit alpha0303
Sodium channel protein type 9 subunit alpha0202
Sodium channel protein type 2 subunit alpha0202
Sodium channel protein type 3 subunit alpha0202
Sodium channel protein type 11 subunit alpha0202
Sodium channel protein type 8 subunit alpha0202
Sodium channel protein type 10 subunit alpha0202
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0102
DNA gyrase subunit A0406
DNA gyrase subunit B0406
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0102
DNA topoisomerase 2-alpha0104
DNA gyrase subunit A0102
Multidrug resistance protein MdtK0011
DNA gyrase subunit B0303
DNA gyrase subunit A0303
Enoyl-[acyl-carrier-protein] reductase [NADH]0409
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Beta-lactamase0202
Proto-oncogene tyrosine-protein kinase Src0101
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0001
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Beta-lactamase 0303
Beta-lactamase0505
Neutrophil elastase0101
Cytochrome P450 2B60516
Beta-lactamase0101
Beta-lactamase 0101
Beta-lactamase 0202
dopamine D1 receptor4004
atrial natriuretic peptide receptor 1 precursor3003
Glucocorticoid receptor010318
Sex hormone-binding globulin0022
Glycine receptor subunit alpha-1010010
Corticosteroid-binding globulin0303
Glycine receptor subunit beta010010
Glycine receptor subunit alpha-2010010
Glycine receptor subunit alpha-3010010
Potassium voltage-gated channel subfamily A member 10112
Inositol monophosphatase 15005
Isocitrate lyase0202
Mas-related G-protein coupled receptor member X20022
Hsf1 protein0022
Pantothenate synthetase0202
parathyroid hormone/parathyroid hormone-related peptide receptor precursor7007
Polyphenol oxidase 20203
unnamed protein product0101
heat shock protein HSP 90-alpha isoform 20002
Histone deacetylase 30303
Rap guanine nucleotide exchange factor 35005
Chymotrypsinogen A0202
Steroid 17-alpha-hydroxylase/17,20 lyase0404
Heme oxygenase 1 0101
ATP-dependent translocase ABCB10404
Lanosterol 14-alpha demethylase0134
Aromatase0505
Cytochrome P450 11B1, mitochondrial0303
Cytochrome P450 11B2, mitochondrial0303
ATP-dependent translocase ABCB10404
Heme oxygenase 20101
Malate dehydrogenase, cytoplasmic0202
Histone deacetylase 40202
Cytochrome P450 1440033
Steroid C26-monooxygenase0033
Steroid C26-monooxygenase0033
Mycocyclosin synthase0011
Lanosterol 14-alpha demethylase0011
Lanosterol 14-alpha demethylase0011
Histone deacetylase 10303
Lanosterol 14-alpha demethylase0527
Sterol 14-alpha demethylase0033
Sterol 14-alpha demethylase0224
Histone deacetylase 70202
Histone deacetylase 20303
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0202
14-alpha sterol demethylase 0033
Histone deacetylase 80202
Histone deacetylase 60202
Histone deacetylase 90101
Histone deacetylase 50202
heat shock protein 90, putative0002
likely tRNA 2'-phosphotransferase0101
Chain A, Uracil Phosphoribosyltransferase0101
Skn7p0001
Thrombopoietin3003
Vpr6006
Thymidylate synthase0101
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0101
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0101
Menin0011
Lecithin retinol acyltransferase0101
Lethal factor0101
Protein Rev 0022
Tyrosyl-DNA phosphodiesterase 10101
thyrotropin-releasing hormone receptor4004
Glucose-6-phosphate 1-dehydrogenase0101
Serum paraoxonase/arylesterase 10202
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Adenosine receptor A10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
6-phosphogluconate dehydrogenase, decarboxylating0101
Holo-[acyl-carrier-protein] synthase0101
Solute carrier organic anion transporter family member 2A10101
Sodium/bile acid cotransporter0202
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10202
Chain A, Type Iii Chloramphenicol Acetyltransferase0101
Estrogen receptor0045
Guanine nucleotide-binding protein G4004
Estrogen receptor beta0045
Canalicular multispecific organic anion transporter 10101
large T antigen0101
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]1001
alpha synuclein, partial1001
hypothetical protein, conserved3003
luciferase2002
nuclear receptor subfamily 1, group I, member 24004
Caspase-74004
caspase-34004
histone deacetylase 9 isoform 33003
ubiquitin carboxyl-terminal hydrolase 2 isoform a5005
Muscarinic acetylcholine receptor M2012013
Muscarinic acetylcholine receptor M409010
Muscarinic acetylcholine receptor M509010
Adenosine receptor A30606
Muscarinic acetylcholine receptor M109010
Androgen receptor011012
Alpha-1B adrenergic receptor011112
Muscarinic acetylcholine receptor M309010
Substance-K receptor0606
Acetylcholinesterase0202
Glutamate receptor ionotropic, kainate 11001
Histamine H2 receptor010010
Adenosine receptor A2a0505
Mu-type opioid receptor0618
Kappa-type opioid receptor08110
Glutamate receptor ionotropic, kainate 21001
Glutamate receptor ionotropic, kainate 31001
Alpha-1A adrenergic receptor011112
Disintegrin and metalloproteinase domain-containing protein 173003
Fatty-acid amide hydrolase 11001
Glutamate receptor ionotropic, kainate 41001
Leukotriene B4 receptor 11002
Glutamate receptor ionotropic, kainate 51001
Leukotriene B4 receptor 21002
Carbonic anhydrase 0202
Carbonic anhydrase0202
Carbonic anhydrase0202
Carbonic anhydrase, alpha family 0303
Carbonic anhydrase0202
Carbonic anhydrase 0202
Carbonic anhydrase 0202
Delta-type opioid receptor0305
Mu-type opioid receptor0418
Mu-type opioid receptor0404
Carbonic anhydrase 0202
Delta carbonic anhydrase0202
Genome polyprotein 0101
Spike glycoprotein0022
Replicase polyprotein 1ab0022
Transmembrane protease serine 20022
Procathepsin L0022
Replicase polyprotein 1a0022
Replicase polyprotein 1ab0022
Replicase polyprotein 1ab0224
Replicase polyprotein 1ab0527
Sigma intracellular receptor 20101
Cyclic GMP-AMP synthase0101
Angiotensin-converting enzyme 2 0022
Toll-like receptor 90101
Toll-like receptor 70101
Tyrosine-protein kinase ABL10112
Cytochrome P450 2C80203
Mast/stem cell growth factor receptor Kit0112
Breakpoint cluster region protein0011
Platelet-derived growth factor receptor alpha0112
Cytochrome P450 3A50102
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Beta-lactamase 0001
Beta-lactamase 0001
GTP-binding nuclear protein Ran isoform 12002
3-oxoacyl-[acyl-carrier-protein] synthase 3 0202
N-glycosylase/DNA lyase0101
Myeloperoxidase0101
Formamidopyrimidine-DNA glycosylase0101
Cytochrome P450 2A60101
Macrophage migration inhibitory factor0101
Endonuclease III-like protein 10101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0101
Endonuclease 8-like 10101
GALC protein6006
3-oxoacyl-[acyl-carrier-protein] synthase 30101
Gap junction alpha-1 protein0101
Gap junction beta-2 protein0101
Acyl-protein thioesterase 10101
Estrogen receptor beta0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Cytochrome P450 26A10101
Prostaglandin G/H synthase 1 0202
Prostaglandin G/H synthase 2 0202
3',5'-cyclic-AMP phosphodiesterase 0101
Camphor 5-monooxygenase0001
Phospholipase A2, major isoenzyme0101
Epoxide hydrolase 10001
Cytochrome P450 2C11 0101
Steroid 21-hydroxylase0101
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Polyunsaturated fatty acid 5-lipoxygenase0202
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
5-hydroxytryptamine receptor 2A0808
Indoleamine 2,3-dioxygenase 10101
Cytochrome P450 2A20101
Cytochrome P450 11B1, mitochondrial 0101
Translocator protein0112
Cytochrome P450 7A1 0101
Estrogen receptor0101
Thromboxane-A synthase 0303
Gonadotropin-releasing hormone receptor0112
Type-1 angiotensin II receptor0101
Delta-type opioid receptor0618
Cytochrome P450 4F20101
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0101
Cytochrome P450 7A10101
Lanosterol 14-alpha demethylase 0202
Amine oxidase [flavin-containing] B0101
Amine oxidase [flavin-containing] A0303
Amine oxidase [flavin-containing] B0101
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial0101
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0101
Renin0101
Prothrombin0213
Prothrombin 0101
Coagulation factor X0202
Plasminogen0101
Tissue-type plasminogen activator0101
Cationic trypsin0101
Trypsin-10101
Trypsin-20101
Trypsin-30101
Chain E, Fibrin beta chain0101
T cell receptor, partial1001
luteinizing hormone receptor1001
integrase, partial0101
chaperonin-containing TCP-1 beta subunit homolog1001
lens epithelium-derived growth factor p750101
Caspase 6, apoptosis-related cysteine peptidase0001
PPM1D protein5005
TSHR protein1001
Apoptotic peptidase activating factor 10101
isocitrate dehydrogenase 1, partial1001
serine-protein kinase ATM isoform a1001
neutrophil cytosol factor 10101
caspase-9 isoform alpha precursor0101
pyruvate kinase PKM isoform a2002
caspase-3 isoform a preproprotein0101
replicative DNA helicase0001
recombinase A0011
POsterior Segregation0011
neuropeptide S receptor isoform A2002
Glutathione reductase0101
Glycoprotein hormones alpha chain1001
Albumin0001
Dihydrolipoyl dehydrogenase, mitochondrial0102
Microtubule-associated protein tau0112
Alpha-1D adrenergic receptor0516
Cruzipain0101
Thioredoxin reductase 1, cytoplasmic0102
Dihydrolipoyl dehydrogenase 0102
Zinc finger protein mex-50011
Nuclear receptor subfamily 1 group I member 20011
DNA polymerase III, partial2002
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
Thioredoxin reductase 0101
Flavodoxin0001
5-hydroxytryptamine receptor 3E0101
ras-related protein Rab-9A4004
5-hydroxytryptamine receptor 3B0101
5-hydroxytryptamine receptor 1A0213
5-hydroxytryptamine receptor 2C0404
Muscarinic acetylcholine receptor M50314
D0202
D(3) dopamine receptor0202
Alpha-2B adrenergic receptor0415
Endothelin receptor type B0101
D(4) dopamine receptor0505
Alpha-2C adrenergic receptor0415
Alpha-2A adrenergic receptor0415
5-hydroxytryptamine receptor 3A0202
Endothelin receptor type B0101
Endothelin-1 receptor0101
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1D0202
5-hydroxytryptamine receptor 1F0202
5-hydroxytryptamine receptor 2B0404
5-hydroxytryptamine receptor 60101
Histamine H1 receptor0202
Sodium-dependent serotonin transporter0505
5-hydroxytryptamine receptor 7 0202
5-hydroxytryptamine receptor 70303
Alpha-1A adrenergic receptor0101
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
Histamine H1 receptor0404
5-hydroxytryptamine receptor 3A0202
5-hydroxytryptamine receptor 3A0101
Angiotensin-converting enzyme0303
D(2) dopamine receptor0404
5-hydroxytryptamine receptor 4 0101
5-hydroxytryptamine receptor 3D0101
5-hydroxytryptamine receptor 3C0101
5-hydroxytryptamine receptor 3B0202
5-hydroxytryptamine receptor 3B0202
G-protein coupled receptor 0101
Transporter0303
Cyclin-dependent kinase 10101
Platelet-activating factor receptor0101
M-phase inducer phosphatase 10101
RAC-alpha serine/threonine-protein kinase0101
Stromelysin-10101
Matrilysin0101
Multidrug transporter MdfA0101
Protein mono-ADP-ribosyltransferase PARP150101
Nuclear receptor corepressor 10101
Integrin beta-10101
Leukotriene A-4 hydrolase0101
Integrin alpha-40101
Nuclear receptor corepressor 20101
Opioid receptor, delta 1b 0101
Acetylcholinesterase0101
Opioid receptor homologue0101
Acyl-CoA desaturase 10101
Muscarinic acetylcholine receptor M10213
Muscarinic acetylcholine receptor M30213
Muscarinic acetylcholine receptor M40213
Muscarinic acetylcholine receptor M20213
Histidine decarboxylase0011
Proteinase-activated receptor 10112
Kappa-type opioid receptor0215
Kappa-type opioid receptor0214
UDP-glucuronosyltransferase 1A30001
Mu-type opioid receptor0216
Nociceptin receptor0101
5-hydroxytryptamine receptor 70202
Mu-type opioid receptor0101
Mu-type opioid receptor0101
Chain A, Isoleucyl-tRNA synthetase0101
twin arginine protein translocation system - TatA protein0002
Isoleucine--tRNA ligase0101
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial0101
beta-2 adrenergic receptor2002
eyes absent homolog 2 isoform a1001
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Phospholipase A2, membrane associated0001
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Potassium voltage-gated channel subfamily A member 50101
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Platelet-activating factor receptor0001
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Indoleamine 2,3-dioxygenase 10101
Adenosine receptor A10404
Adenosine receptor A2a0101
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
C-C chemokine receptor type 20202
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
C-terminal-binding protein 11001
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Myosin light chain kinase, smooth muscle0101
Transient receptor potential cation channel subfamily A member 10011
Potassium channel subfamily K member 2 0101
Indoleamine 2,3-dioxygenase 20101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
ClpP1001
Mcl-10101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
Sodium/potassium-transporting ATPase subunit alpha-1 0101
Sodium/potassium-transporting ATPase subunit beta-10101
Sodium/potassium-transporting ATPase subunit alpha-30101
Sodium/potassium-transporting ATPase subunit beta-20101
Bifunctional cytochrome P450/NADPH--P450 reductase0011
UDP-glucuronosyltransferase 2B70102
Potassium-transporting ATPase subunit beta0101
Potassium-transporting ATPase alpha chain 10101
Potassium-transporting ATPase alpha chain 10101
UDP-glucuronosyltransferase 1A40103
Bombesin receptor subtype-30011
UDP-glucuronosyltransferase 2B10 0101
Fatty acid synthase0202
Sodium/potassium-transporting ATPase subunit alpha-20101
Potassium-transporting ATPase subunit beta0101
Potassium-transporting ATPase alpha chain 20001
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit gamma0101
WD repeat-containing protein 50101
Glutathione S-transferase omega-10202
Histone-lysine N-methyltransferase 2A0101
Sodium/potassium-transporting ATPase subunit alpha-40101
Cytosolic endo-beta-N-acetylglucosaminidase0101
Muscarinic acetylcholine receptor0101
MecA 0101
Valosin-containing protein0101
microphthalmia-associated transcription factor isoform 90101
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
eukaryotic translation initiation factor 4E isoform 10101
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
Photosystem I iron-sulfur center 0001
Beta-lactamase 10001
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Glutamate receptor ionotropic, NMDA 2D0101
Glutamate receptor ionotropic, NMDA 3B0101
Muscarinic acetylcholine receptor M10012
Muscarinic acetylcholine receptor M40012
Glutamate receptor ionotropic, NMDA 1 0202
Lysosomal Pro-X carboxypeptidase0101
Glutamate receptor ionotropic, NMDA 2A 0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0203
Cholinesterase0101
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 2D0202
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0202
Muscarinic acetylcholine receptor M50012
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
Sigma non-opioid intracellular receptor 10303
Glutamate receptor ionotropic, NMDA 3A0202
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Prostaglandin G/H synthase 2 0101
Prostaglandin G/H synthase 1 0101
Sterol 14-alpha-demethylase0022
14-alpha sterol demethylase 0022
14-alpha sterol demethylase 0022
luciferase0001
Fatty acid-binding protein, liver0101
Progesterone receptor0517
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0416
Androgen receptor0415
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0527
NAD-dependent protein deacetylase sirtuin-60101
DNA-directed RNA polymerase subunit beta0101
Solute carrier organic anion transporter family member 1A40101
Solute carrier organic anion transporter family member 2B1 0202
NH(3)-dependent NAD(+) synthetase0101
Arylacetamide deacetylase0102
Caspase-10101
Solute carrier organic anion transporter family member 1A10101
Solute carrier organic anion transporter family member 1A20101
DNA-directed RNA polymerase subunit beta0101
Solute carrier organic anion transporter family member 1B30203
Solute carrier organic anion transporter family member 1B10304
Chain A, Mineralocorticoid receptor0101
Chain A, Mineralocorticoid receptor0101
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
Metallo-beta-lactamase type 20202
exodeoxyribonuclease V subunit RecD0101
exodeoxyribonuclease V subunit RecB0101
exodeoxyribonuclease V subunit RecC0101
ATP-dependent 6-phosphofructokinase0101
Dihydropteroate synthase0101
Dihydrofolate reductase0101
Endothelin-1 receptor0101
Protease 0213
Carbonic anhydrase 0001
Carbonic anhydrase0101
Carbonic anhydrase 20112
Cholinesterase0101
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase0101
Carbonic anhydrase 0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase 0101
Carbonic anhydrase 130101
Carbonic anhydrase 40101
Protein argonaute-20011
Serine/threonine-protein kinase mTOR0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0202
Peptidyl-prolyl cis-trans isomerase FKBP50101
Splicing factor 3B subunit 30101
Chain A, CES1 protein0101
NPC intracellular cholesterol transporter 1 precursor3003
interferon gamma precursor0001
Serine/threonine-protein kinase D30101
Lysosomal acid glucosylceramidase0011
Protein kinase C gamma type0101
Protein kinase C alpha type0101
Protein kinase C beta type0101
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
Protein kinase C alpha type0101
Protein kinase C eta type0101
Substance-P receptor0202
B2 bradykinin receptor0202
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 50202
Protein kinase C iota type0101
Melanocortin receptor 30202
Estrogen-related receptor gamma0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Phospholipase D1 0101
Protein kinase C epsilon type0101
Protein kinase C theta type0101
Protein kinase C zeta type0101
Protein kinase C delta type0101
Platelet-activating factor acetylhydrolase0101
Phospholipase D10101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0213
Serine/threonine-protein kinase D10101
Protein kinase C eta type0101
Emopamil-binding protein-like0101
7-dehydrocholesterol reductase0112
Protein kinase C theta type0101
Sodium- and chloride-dependent taurine transporter0101
Proton-coupled amino acid transporter 10101
B2 bradykinin receptor0101
Beta-lactamase0101
Metallo-beta-lactamase L1 type 30101
Beta-lactamase 0101
Snq2p0001
Albumin0022
Tryptophan 5-hydroxylase 10101
Sodium-dependent dopamine transporter0101
D(1B) dopamine receptor0101
D(4) dopamine receptor0101
Pleiotropic ABC efflux transporter of multiple drugs0102
Proteasome subunit alpha type-60011
Cathepsin D 0101
Aldehyde oxidase0002
Mucosa-associated lymphoid tissue lymphoma translocation protein 10101
Vasopressin V2 receptor0202
Vasopressin V1a receptor0202
MSH0001
pyruvate kinase1001
pyruvate kinase PKM isoform b1001
Hematopoietic prostaglandin D synthase0101
Transient receptor potential cation channel subfamily A member 10101
Ornithine decarboxylase1001
NACHT, LRR and PYD domains-containing protein 3 0101
Transient receptor potential cation channel subfamily V member 20101
Chain A, enoyl-acyl carrier reductase0101
Chain C, enoyl-acyl carrier reductase0101
Chain A, enoyl-acyl carrier reductase0101
Chain C, enoyl-acyl carrier reductase0101
Chain A, enoyl-acyl carrier reductase0101
Chain C, enoyl-acyl carrier reductase0101
Chain A, Repressor0011
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI0101
Endoplasmic reticulum chaperone BiP0101
Carbonyl reductase [NADPH] 10202
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI0101
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI0101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI0202
Enoyl-acyl carrier reductase0101
Enoyl-acyl-carrier protein reductase 0202
Enoyl-ACP reductase II 0101
D-alanyl-D-alanine dipeptidase0101
Cholesterol side-chain cleavage enzyme, mitochondrial 0011
Cholesterol 24-hydroxylase0213
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]