A phytohormone that promote cell division, or cytokinesis, in plant roots and shoots.
ChEBI ID: 23530
| Member | Definition | Class |
|---|---|---|
| 1,3-diphenylurea | A member of the class of phenylureas that is urea in which one of the hydrogens of each amino group is replaced by a phenyl group. It is present in coconut milk (Cocos nucifera). | 1,3-diphenylurea |
| benzylaminopurine | A member of the class of 6-aminopurines that is adenine in which one of the hydrogens of the amino group is replaced by a benzyl group. | N-benzyladenine |
| kinetin | A member of the class of 6-aminopurines that is adenine carrying a (furan-2-ylmethyl) substituent at the exocyclic amino group. | kinetin |
| n(6)-(delta(2)-isopentenyl)adenine | A 6-isopentenylaminopurine in which has the isopentenyl double bond is located between the 2 and 3 positions of the isopentenyl group. | N(6)-dimethylallyladenine |
| zeatin riboside | A 9-ribosylzeatin having trans-zeatin as the nucleobase. | 9-ribosyl-trans-zeatin |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 134 (11.50) | 18.7374 |
| 1990's | 150 (12.88) | 18.2507 |
| 2000's | 409 (35.11) | 29.6817 |
| 2010's | 374 (32.10) | 24.3611 |
| 2020's | 98 (8.41) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 2 (0.13%) | 5.53% |
| Reviews | 25 (1.56%) | 6.00% |
| Case Studies | 1 (0.06%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 1,572 (98.25%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 34.8881 | 7 | 11 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 30.0935 | 3 | 5 |
| BRCA1 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 9.2004 | 2 | 3 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 50.1187 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 12,559.4550 | 1 | 2 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 1.2247 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 42.2789 | 7 | 15 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 19.6325 | 6 | 9 |
| geminin | Homo sapiens (human) | Potency | 0.6250 | 2 | 4 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 30.6379 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 45.8889 | 1 | 3 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 38.2695 | 2 | 6 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 28.1838 | 1 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 12.5893 | 2 | 2 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 6.3571 | 1 | 1 |
| luciferase | Photuris pensylvanica (Pennsylania firefly) | Potency | 11.2202 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 4.7308 | 1 | 1 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 0.8413 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 3.5481 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 27.2861 | 3 | 7 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 24.5412 | 1 | 1 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 11.2202 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 17.2803 | 2 | 3 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 30.7625 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 6.2714 | 2 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 12.9845 | 3 | 5 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 11.9087 | 1 | 3 |
| TDP1 protein | Homo sapiens (human) | Potency | 27.8763 | 2 | 5 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 21.7782 | 1 | 1 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 18.3281 | 2 | 5 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 11.2202 | 1 | 1 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 11.2202 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 1.2589 | 1 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 45.8889 | 1 | 3 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 7,8-dihydro-8-oxoguanine triphosphatase | Homo sapiens (human) | IC50 | 24.5000 | 1 | 2 |
| Acidic mammalian chitinase | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | IC50 | 0.3950 | 2 | 2 |
| Chain A, Cell division protein kinase 2 | Homo sapiens (human) | Ki | 78.0000 | 1 | 1 |
| Chain A, Endochitinase | Saccharomyces cerevisiae (brewer's yeast) | Ki | 3.2000 | 1 | 3 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Endochitinase | Saccharomyces cerevisiae S288C | Ki | 3.2000 | 1 | 1 |
| Endochitinase A1 | Aspergillus fumigatus | IC50 | 1,000.0000 | 1 | 1 |
| Epoxide hydrolase B | Mycobacterium tuberculosis CDC1551 | IC50 | 0.0190 | 2 | 2 |
| Phosphatidylinositol 4-kinase alpha | Homo sapiens (human) | IC50 | 240.4000 | 1 | 1 |
| Phosphatidylinositol 4-kinase alpha | Homo sapiens (human) | Ki | 199.0000 | 1 | 1 |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | IC50 | 240.4000 | 1 | 1 |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | Ki | 199.0000 | 1 | 1 |
| Phosphatidylinositol 4-kinase type 2-alpha | Homo sapiens (human) | IC50 | 240.4000 | 1 | 1 |
| Phosphatidylinositol 4-kinase type 2-alpha | Homo sapiens (human) | Ki | 199.0000 | 1 | 1 |
| Phosphatidylinositol 4-kinase type 2-beta | Homo sapiens (human) | IC50 | 240.4000 | 1 | 1 |
| Phosphatidylinositol 4-kinase type 2-beta | Homo sapiens (human) | Ki | 199.0000 | 1 | 1 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | IC50 | 660.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Chain A, Pr10.2b | Lupinus luteus (yellow lupine) | Kd | 4.2000 | 1 | 1 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | Kd | 247.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Cytokinin dehydrogenase 1 | Zea mays | Km | 15.7000 | 1 | 2 |
| Phosphatidylinositol 4-kinase alpha | Homo sapiens (human) | Km | 239.0000 | 1 | 1 |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | Km | 239.0000 | 1 | 1 |
| Phosphatidylinositol 4-kinase type 2-alpha | Homo sapiens (human) | Km | 239.0000 | 1 | 1 |
| Phosphatidylinositol 4-kinase type 2-beta | Homo sapiens (human) | Km | 239.0000 | 1 | 1 |