Page last updated: 2024-08-05 11:30:43
benzimidazole
A mancude organic heterobicyclic parent that is a heterocyclic organic compound comprising fused benzene and imidazole rings.
ChEBI ID: 36622
Members (3)
Member | Definition | Role |
benzimidazole | The 1H-tautomer of benzimidazole. | 1H-benzimidazole |
ledipasvir | A benzimidazole derivative that is used in combination with sofosbuvir (under the trade name Harvoni) for the treatment of chronic hepatitis C genotype 1 infection. | ledipasvir |
pracinostat | A hydroxamic acid that is N-hydroxyacrylamide which is substituted at position 3 by a 2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl group (the E isomer). An orally available pan-histone deacetylase inhibitor with demonstrated activity in the treatment of advanced solid tumours. | pracinostat |
Research
Studies (1,535)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
pre-1990 | 94 (6.12) | 18.7374 |
1990's | 49 (3.19) | 18.2507 |
2000's | 265 (17.26) | 29.6817 |
2010's | 916 (59.67) | 24.3611 |
2020's | 211 (13.75) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
Trials | 82 (5.21%) | 5.53% |
Reviews | 96 (6.10%) | 6.00% |
Case Studies | 44 (2.79%) | 4.05% |
Observational | 20 (1.27%) | 0.25% |
Other | 1,333 (84.63%) | 84.16% |