Page last updated: 2024-12-05

glyphosphine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

glyphosine : A tertiary amino compound that consists of glycine bearing two N-phosphonomethyl substituents. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

FloraRankFlora DefinitionFamilyFamily Definition
GlycinegenusA non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.[MeSH]FabaceaeThe large family of plants characterized by pods. Some are edible and some cause LATHYRISM or FAVISM and other forms of poisoning. Other species yield useful materials like gums from ACACIA and various LECTINS like PHYTOHEMAGGLUTININS from PHASEOLUS. Many of them harbor NITROGEN FIXATION bacteria on their roots. Many but not all species of beans belong to this family.[MeSH]

Cross-References

ID SourceID
PubMed CID17112
CHEMBL ID265954
CHEBI ID63484
SCHEMBL ID67368
MeSH IDM0120835

Synonyms (54)

Synonym
AC-12519
nsc-18468
caswell no. 471a
glyphosine
glycine, n,n-bis(phosphonomethyl)-
epa pesticide chemical code 103602
cp 41845
glyphosphine
glyphosine [ansi]
n,n-bis(phosphonomethyl)glycine
einecs 219-468-4
brn 1884944
NCGC00160488-01
CHEMBL265954
chebi:63484 ,
2-[bis(phosphonomethyl)amino]acetic acid
2-(bis(phosphonomethyl)amino)acetic acid
oxhdyfkenbxuem-uhfffaoysa-
inchi=1/c4h11no8p2/c6-4(7)1-5(2-14(8,9)10)3-15(11,12)13/h1-3h2,(h,6,7)(h2,8,9,10)(h2,11,12,13)
glycine-n,n-bis(methylenephosphonic acid)
G0229
2439-99-8
AKOS003600176
[carboxymethyl(phosphonomethyl)azaniumyl]methyl-hydroxyphosphinate
C19132
glyphosine [ansi:iso]
2u96121skr ,
unii-2u96121skr
n-(carboxymethyl)iminodi(methylphosphinic acid)
FT-0629425
n,n-bis(phosphonomethyl)aminoacetic acid
EPITOPE ID:167841
glyphosine [mi]
mon-845
cp-41845
gdmp
n,n-bis(phosphonomethyl)aminoacetic
glycinedimethanephosphonic acid
nitrilomonoacetic acid dimethylenephosphonic acid
nitrilomonomethylcarbonyldimethylphosphonic acid
glyphosine [iso]
n,n-di(phosphonomethyl)glycine
SCHEMBL67368
DTXSID2044557
[bis(phosphonomethyl)amino]acetic acid #
acetic acid, 2-bis(phosphonatomethyl)amino-
OXHDYFKENBXUEM-UHFFFAOYSA-N
mfcd00056670
n,n-bis(phosphonomethyl)glycine, >=98.0% (t)
J-015499
Q27132652
AS-15131
glycinedimethanephosphonic acid;c 9552; cp 41845; gdmp;polaris
D90732

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" Most of the effects for both compounds followed a typical dose-response curve, but GPS gave a bimodal response in certain tests."( Influence of feeding chlorocholine chloride and glyphosine on selected immune parameters in deer mice, Peromyscus maniculatus.
Hinsdill, RD; Olson, LJ, 1984
)
0.27
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
plant growth retardantnull
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (3)

ClassDescription
glycine derivativeA proteinogenic amino acid derivative resulting from reaction of glycine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
phosphonic acidsHP(=O)(OH)2 (phosphonic acid) and its P-substituted derivatives.
tertiary amino compoundA compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID328053Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage at 200 nM2007Proceedings of the National Academy of Sciences of the United States of America, Jul-24, Volume: 104, Issue:30
Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (12.50)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.60

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.60 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.80 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.60)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]