Page last updated: 2024-11-12
glaziovianin a
Description
Research Excerpts
Clinical Trials
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Study Profile
Bioassays
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Description
glaziovianin A: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 16747686 |
CHEMBL ID | 234716 |
MeSH ID | M0511966 |
Synonyms (5)
Synonym |
---|
glaziovianin a |
CHEMBL234716 |
3-(4,7-dimethoxy-1,3-benzodioxol-5-yl)-6,7-dimethoxy-4h-chromen-4-one |
3-(4,7-dimethoxy-1,3-benzodioxol-5-yl)-6,7-dimethoxychromen-4-one |
AKOS037480543 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (63)
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID295986 | Cytotoxicity against human SF539 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID295978 | Cytotoxicity against human HBC4 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID1315233 | Growth inhibition of human PC3 cells measured after 48 hrs by MTS assay | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5 | Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity. |
AID1316906 | Inhibition of [3H]colchicine binding to microtubule associated proteins free porcine brain alpha/beta-tubulin assessed as remaining radiolabeled binding at 100 uM measured after 5 mins by centrifugal gel filtration method relative to control | 2016 | Bioorganic & medicinal chemistry, 11-01, Volume: 24, Issue:21 | Discovery of O |
AID295991 | Cytotoxicity against human HT29 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID1315228 | Antimitotic activity against sea urchin Paracentrotus lividus L embryo assessed as induction of cleavage arrest | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5 | Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity. |
AID295977 | Cytotoxicity against human HL60 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID295995 | Cytotoxicity against human HCIH226 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID295982 | Cytotoxicity against human MDA-MB-231 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID295999 | Cytotoxicity against human DMS273 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID296015 | Cytotoxicity against human DU145 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID296018 | Cell cycle arrest in rat 3Y1 cells by accumulation at M phase at 3 uM after 18 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID296013 | Cytotoxicity against human MKN45 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID1316908 | Binding affinity to porcine alpha/beta tubulin assessed as decrease in tryptophan fluorescence measured after 30 mins by tryptophan fluorescence assay | 2016 | Bioorganic & medicinal chemistry, 11-01, Volume: 24, Issue:21 | Discovery of O |
AID295985 | Cytotoxicity against human SF295 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID296000 | Cytotoxicity against human DMS114 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID296010 | Cytotoxicity against human MKN1 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID1316907 | Inhibition of [3H]vinblastine binding to microtubule associated proteins free porcine brain alpha/beta-tubulin assessed as remaining radiolabeled binding at 100 uM measured after 5 mins by centrifugal gel filtration method relative to control | 2016 | Bioorganic & medicinal chemistry, 11-01, Volume: 24, Issue:21 | Discovery of O |
AID296001 | Cytotoxicity against human LOX-IMVI cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID296014 | Cytotoxicity against human MKN74 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID1316909 | Inhibition of bipolar spindle formation in human HeLa cells at 1 uM measured after 6 hrs by DAPI staining-based fluorescence microscopic analysis | 2016 | Bioorganic & medicinal chemistry, 11-01, Volume: 24, Issue:21 | Discovery of O |
AID295994 | Cytotoxicity against human NCIH23 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID295983 | Cytotoxicity against human U251 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID1315232 | Growth inhibition of human DU145 cells measured after 48 hrs by MTS assay | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5 | Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity. |
AID296008 | Cytotoxicity against human ACHN cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID502425 | Cytotoxicity against human HeLaS3 cells after 48 hrs by WAT-8 assay | 2010 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 20, Issue:18 | Structure-activity relationship study of glaziovianin A against cell cycle progression and spindle formation of HeLa S3 cells. |
AID295997 | Cytotoxicity against human NCIH460 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID295988 | Cytotoxicity against human SNB78 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID296009 | Cytotoxicity against human St4 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID1315229 | Antimitotic activity against sea urchin Paracentrotus lividus L embryo assessed as induction of embryo spinning | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5 | Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity. |
AID295998 | Cytotoxicity against human A549 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID296007 | Cytotoxicity against human RXF631L cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID502427 | Cell cycle arrest in human HeLaS3 cells assessed as accumulation at M phase at 1 uM after 18 hrs by flow cytometry | 2010 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 20, Issue:18 | Structure-activity relationship study of glaziovianin A against cell cycle progression and spindle formation of HeLa S3 cells. |
AID295981 | Cytotoxicity against human MCF7 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID1315226 | Growth inhibition of human HCT116 cells measured after 48 hrs by MTS assay | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5 | Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity. |
AID688487 | Cytotoxicity against human HeLaS3 cells after 48 hrs by WST8 assay | 2012 | Bioorganic & medicinal chemistry, Oct-01, Volume: 20, Issue:19 | Design, synthesis, and biological evaluation of the analogues of glaziovianin A, a potent antitumor isoflavone. |
AID295992 | Cytotoxicity against human HCT15 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID1315230 | Growth inhibition of human A549 cells by MTS assay | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5 | Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity. |
AID295984 | Cytotoxicity against human SF268 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID295996 | Cytotoxicity against human NCIH522 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID295993 | Cytotoxicity against human HCT116 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID296012 | Cytotoxicity against human MKN28 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID1315234 | Growth inhibition of human MDA-MB-231 cells measured after 48 hrs by MTS assay | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5 | Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity. |
AID1316903 | Cytotoxicity against human HeLa cells assessed as reduction in cell growth measured after 48 hrs by WST-8 assay | 2016 | Bioorganic & medicinal chemistry, 11-01, Volume: 24, Issue:21 | Discovery of O |
AID296004 | Cytotoxicity against human OVCAR5 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID296002 | Cytotoxicity against human OVCAR-3 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID296017 | Disruption of microtubules in rat 3Y1 cells at 1 uM after 18 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID296011 | Cytotoxicity against human MKN7 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID296016 | Cytotoxicity against human PC3 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID295990 | Cytotoxicity against human KM12 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID295987 | Cytotoxicity against human SNB75 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID296006 | Cytotoxicity against human SK-OV3 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID1315227 | Antimitotic activity in sea urchin Paracentrotus lividus L embryo assessed as induction of cleavage alteration | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5 | Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity. |
AID688489 | Cell cycle arrest in human HeLaS3 cells assessed as accumulation at G2/M phase at 1 uM after 24 hrs by flow cytometric analysis | 2012 | Bioorganic & medicinal chemistry, Oct-01, Volume: 20, Issue:19 | Design, synthesis, and biological evaluation of the analogues of glaziovianin A, a potent antitumor isoflavone. |
AID1315235 | Growth inhibition of human SKOV3 cells measured after 48 hrs by MTS assay | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5 | Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity. |
AID1315231 | Growth inhibition of human A375 cells measured after 48 hrs by MTS assay | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5 | Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity. |
AID296005 | Cytotoxicity against human OVCAR8 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID295979 | Cytotoxicity against human BSY1 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID1315236 | Growth inhibition of human PBMC cells measured after 48 hrs by MTS assay | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5 | Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity. |
AID295980 | Cytotoxicity against human HBC5 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID295989 | Cytotoxicity against human HCC2998 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID296003 | Cytotoxicity against human OVCAR4 cells by MTT assay after 72 hrs | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells. |
AID688490 | Induction of mitotic arrest in human HeLaS3 cells assessed as abnormal multipolar spindles at 1 uM after 6 hrs by immunofluorescence staining | 2012 | Bioorganic & medicinal chemistry, Oct-01, Volume: 20, Issue:19 | Design, synthesis, and biological evaluation of the analogues of glaziovianin A, a potent antitumor isoflavone. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (9)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (11.11) | 29.6817 |
2010's | 8 (88.89) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 17.88
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (17.88) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 1 (11.11%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 8 (88.89%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |