Compounds > s 1006
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s 1006

Description

S 1006: structure given in first source [MeSH]

cefcapene : A cephalosporin compound having (carbamoyloxy)methyl and N-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino side-groups. It is used (generally as the corresponnding pivaloyloxymethyl ester prodrug) as an oral antibacterial. [CHeBI]

Cross-References

ID SourceID
PubMed CID6436055
CHEMBL ID582912
SCHEMBL ID419453
CHEBI ID131729
MeSH IDM0204874

Synonyms (29)

Synonym
s 1006
cfpn
D07638
cefcapene (inn)
CHEMBL582912
(6r,7r)-7-{[(2z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino}-3-[(carbamoyloxy)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CHEBI:131729
cefcapeno
cefcapene
cefcapenum
(6r,7r)-7-[[(z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
4d5d3422mw ,
(6r,7r)-7-((z)-2-(2-amino-4-thiazolyl)-2-pentenamido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, carbamate (ester)
cefcapene pivoxil free acid
cefcapene [inn]
s-1006 ,
unii-4d5d3422mw
5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)-7-((2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl)amino)-8-oxo-, (6r-(6alpha,7beta(z)))-
AKOS015915643
cefcapene [mi]
cefcapene [who-dd]
SCHEMBL419453
C21547
(6r,7r)-3-[[(aminocarbonyl)oxy]methyl]-7-[[(2z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Q5057225
DB13461
DTXSID201027544
gtpl12053
flomox (cefcapene pivoxil)

Roles (1)

RoleDescription
antibacterial drugA drug used to treat or prevent bacterial infections.

Drug Classes (6)

ClassDescription
cephalosporinA class of beta-lactam antibiotics differing from the penicillins in having a 6-membered, rather than a 5-membered, side ring. Although cephalosporins are among the most commonly used antibiotics in the treatment of routine infections, and their use is increasing over time, they can cause a range of hypersensitivity reactions, from mild, delayed-onset cutaneous reactions to life-threatening anaphylaxis in patients with immunoglobulin E (IgE)-mediated allergy.
carboxylic acidA carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid.
carbamate esterAny ester of carbamic acid or its N-substituted derivatives.
enamideAn alpha,beta-unsaturated carboxylic acid amide of general formula R(1)R(2)C=CR(3)-C(=O)NR(4)R(5) in which the amide C=O function is conjugated to a C=C double bond at the alpha,beta position.
1,3-thiazoles
secondary carboxamideA carboxamide resulting from the formal condensation of a carboxylic acid with a primary amine; formula RC(=O)NHR(1).

Bioassays (5)

Assay IDTitleYearJournalArticle
AID521323Antimicrobial activity against rifampin-resistant Haemophilus influenzae Rd clone by broth dilution method2008Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5
ISSN: 1098-6596		Comparison of the efficacies of oral beta-lactams in selection of Haemophilus influenzae transformants with mutated ftsI genes.
AID521325Antimicrobial activity against beta lactamase-nonproducing ampicillin-resistant Haemophilus influenzae MSC06663 isolate harboring Met377Ile, Ser385Thr and Asn526Lys mutations in penicillin-binding protein 3 by broth dilution method2008Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5
ISSN: 1098-6596		Comparison of the efficacies of oral beta-lactams in selection of Haemophilus influenzae transformants with mutated ftsI genes.
AID438298Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2X preincubated for 4 hrs before addition of substrate (R)-[2-(benzoylamino)propionylsulfanyl]acetic acid2009Journal of medicinal chemistry, Oct-08, Volume: 52, Issue:19
ISSN: 1520-4804		Discovery of new inhibitors of resistant Streptococcus pneumoniae penicillin binding protein (PBP) 2x by structure-based virtual screening.
AID438297Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2X preincubated for 1 hr before addition of substrate (R)-[2-(benzoylamino)propionylsulfanyl]acetic acid2009Journal of medicinal chemistry, Oct-08, Volume: 52, Issue:19
ISSN: 1520-4804		Discovery of new inhibitors of resistant Streptococcus pneumoniae penicillin binding protein (PBP) 2x by structure-based virtual screening.
AID521324Antimicrobial activity against beta lactamase-nonproducing ampicillin-resistant Haemophilus influenzae MSC06647 isolate harboring Asn526Lys mutation in penicillin-binding protein 3 by broth dilution method2008Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5
ISSN: 1098-6596		Comparison of the efficacies of oral beta-lactams in selection of Haemophilus influenzae transformants with mutated ftsI genes.

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's5 (71.43)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (14.29%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (85.71%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[[1-oxo-2-(1-tetrazolyl)ethyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
0
cephalosporin00low000000
cefuroxime
0
carbamate ester;
cephalosporin		00low000000
cephaloridine
0
beta-lactam antibiotic allergen;
cephalosporin;
semisynthetic derivative		antibacterial drug00low000000
cephalothin
0
azabicycloalkene;
beta-lactam antibiotic allergen;
carboxylic acid;
cephalosporin;
semisynthetic derivative;
thiophenes		antibacterial drug;
antimicrobial agent		00low000000
cephaloglycin
0
beta-lactam antibiotic allergen;
cephalosporin		antimicrobial agent00low000000
cephalonium
0
cephalosporin00low000000
cephalexin
0
beta-lactam antibiotic allergen;
cephalosporin;
semisynthetic derivative		antibacterial drug00low000000
cephapirin
0
cephalosporinantibacterial drug00low000000
cefazolin
0
beta-lactam antibiotic allergen;
cephalosporin;
tetrazoles;
thiadiazoles		antibacterial drug00low000000
7-aminodesacetoxycephalosporanic acid
0
cephalosporin;
monocarboxylic acid		00low000000
cephradine
0
beta-lactam antibiotic allergen;
cephalosporin		antibacterial drug00low000000
cefmetazole
0
cephalosporinantibacterial drug00low000000
ceforanide
0
cephalosporinantibacterial drug00low000000
cefonicid
0
cephalosporinantibacterial drug00low000000
cefotiam
0
beta-lactam antibiotic allergen;
cephalosporin;
semisynthetic derivative		antibacterial drug00low000000
cefoperazone
0
cephalosporinantibacterial drug00low000000
moxalactam
0
cephalosporin;
oxacephem		antibacterial drug00low000000
cefadroxil anhydrous
0
cephalosporinantibacterial drug00low000000
cefaclor anhydrous
0
cephalosporinantibacterial drug;
drug allergen		00low000000
cefprozil
0
cephalosporin;
semisynthetic derivative		antibacterial drug00low000000
cephalosporin c
0
cephalosporinfungal metabolite00low000000
ceftezole
0
cephalosporin;
thiadiazoles		00low000000
cefaloram
0
cephalosporinantibacterial drug00low000000
cefazedone
0
4-pyridones;
carboxylic acid;
cephalosporin;
semisynthetic derivative;
thiadiazoles		antibacterial drug00low000000
cephacetrile
0
cephalosporin00low000000
cefbuperazone
0
cephalosporin;
peptide		00low000000
deacetoxycephalosporin c
0
cephalosporin00low000000
cefoxitin
0
beta-lactam antibiotic allergen;
cephalosporin;
cephamycin;
semisynthetic derivative		antibacterial drug00low000000
glutaryl-7-aminocephalosporanic acid
0
cephalosporin00low000000
cefamandole
0
cephalosporin;
semisynthetic derivative		antibacterial drug00low000000
cefpiramide
0
carboxylic acid;
cephalosporin		antibacterial drug00low000000
cefsulodin
0
cephalosporin;
organosulfonic acid;
primary carboxamide		antibacterial drug00low000000
7-[[2-(4-chloro-3-methyl-1-pyrazolyl)-1-oxopropyl]amino]-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
0
cephalosporin00low000000
3-(acetyloxymethyl)-7-[[3-(4-chloro-3,5-dimethyl-1-pyrazolyl)-2-methyl-1-oxopropyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
0
cephalosporin00low000000
7-[[2-[5-cyclopropyl-3-(difluoromethyl)-1-pyrazolyl]-1-oxoethyl]amino]-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
0
cephalosporin00low000000
7-[[2-(4-chloro-3,5-dimethyl-1-pyrazolyl)-1-oxoethyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
0
cephalosporin00low000000
7432 s
0
cephalosporin;
dicarboxylic acid		antibacterial drug00low000000
cefroxadine
0
cephalosporin00low000000
cefodizime
0
1,3-thiazoles;
cephalosporin;
oxime O-ether		antibacterial drug;
EC 1.14.18.1 (tyrosinase) inhibitor		00low000000
cefixime
0
cephalosporinantibacterial drug;
drug allergen		00low000000
ceftriaxone
0
1,2,4-triazines;
1,3-thiazoles;
cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen;
EC 3.5.2.6 (beta-lactamase) inhibitor		00low000000
cefepime
0
cephalosporin;
oxime O-ether		antibacterial drug00low000000
hr 810
0
cephalosporin;
cyclopentapyridine		00low000000
ceftazidime
0
cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen;
EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor		00low000000
cefetamet
0
cephalosporin00low000000
cefotaxime
0
1,3-thiazoles;
cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen		00low000000
cci 15641
0
cephalosporin00low000000
cefpodoxime
0
carboxylic acid;
cephalosporin		antibacterial drug00low000000
cefuzonam
0
cephalosporinantibacterial drug00low000000
(6R,7R)-7-[[2-(2-amino-4-thiazolyl)-2-hydroxyimino-1-oxoethyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
0
1,3-thiazoles;
cephalosporin;
ketoxime		00low000000
cefatrizine
0
amino acid amide;
carboxylic acid;
cephalosporin;
phenols;
semisynthetic derivative;
triazoles		antibacterial drug;
EC 2.7.11.20 (elongation factor 2 kinase) inhibitor		00low000000
cefpodoxime proxetil
0
carboxylic acid;
carboxylic ester;
cephalosporin		antibacterial drug;
prodrug		00low000000
ceftizoxime
0
cephalosporinantibacterial drug00low000000
cefluprenam
0
cephalosporin;
thiadiazoles		antimicrobial agent00low000000
cefclidin
0
cephalosporin;
thiadiazoles		00low000000
cefdinir
0
cephalosporin;
ketoxime		antibacterial drug00low000000
cefmenoxime
0
cephalosporinantibacterial drug00low000000
ru 29246
0
cephalosporinantibacterial drug00low000000
cefozopran
0
cephalosporin;
imidazopyridazine;
thiadiazoles		00low000000
ppi-0903
0
1,3-thiazoles;
cephalosporin;
iminium betaine;
organic phosphoramidate;
oxime O-ether;
thiadiazoles		antibacterial drug;
antimicrobial agent;
prodrug		00low000000
cefditoren
0
carboxylic acid;
cephalosporin		antibacterial drug00low000000
cefathiamidine
0
cephalosporin00low000000
cephapirin sodium
0
cephalosporin;
organic sodium salt		antibacterial drug00low000000
cefiderocol
0
carboxylic acid;
cephalosporin		antibacterial drug;
siderophore		00low000000
ceftobiprole
0
cephalosporin;
thiadiazoles		antimicrobial agent00low000000
foscarnet
0
carboxylic acid;
one-carbon compound;
phosphonic acids		antiviral drug;
geroprotector;
HIV-1 reverse transcriptase inhibitor;
sodium-dependent Pi-transporter inhibitor		00low000000
bromoacetate
0
carboxylic acid;
organohalogen compound		00low000000
dalapon
0
carboxylic acid;
organohalogen compound		00low000000
alpha-naphthylphthalamic acid
0
carboxylic acid;
dicarboxylic acid monoamide;
N-(1-naphthyl)carboxamide		herbicide00low000000
ethoxyacetic acid
0
carboxylic acid00low000000
diisopropylamine dichloroacetate
0
carboxylic acid;
organohalogen compound		00low000000
2-phenoxypropanoic acid
0
aromatic ether;
carboxylic acid		00low000000
mafenide acetate
0
carboxylic acid00low000000
n-butoxyacetic acid
0
carboxylic acid00low000000
picaridin
0
carboxylic acid;
piperidines		00low000000
als 8123
0
carboxylic acid;
ethanolamines;
secondary amino compound		00low000000
aspartame
0
carboxylic acid;
dipeptide zwitterion;
dipeptide;
methyl ester		apoptosis inhibitor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
environmental contaminant;
micronutrient;
nutraceutical;
sweetening agent;
xenobiotic		00low000000
2-(4-methoxyphenoxy)propanoic acid
0
aromatic ether;
carboxylic acid		00low000000
alpha-fluoro-beta-ureidopropionic acid
0
carboxylic acid;
organohalogen compound		00low000000
5-oxo-1-(2-phenylethyl)-3-pyrrolidinecarboxylic acid
0
carboxylic acid;
pyrrolidinecarboxylic acid		00low000000
4-(2-benzamidoethylamino)-1-piperidinecarboxylic acid ethyl ester
0
carboxylic acid;
piperidines		00low000000
1-(4,6-dimethyl-2-pyrimidinyl)-4-piperidinecarboxylic acid
0
carboxylic acid;
piperidines		00low000000
1-(1-oxo-2-thiophen-2-ylethyl)-4-piperidinecarboxylic acid ethyl ester
0
carboxylic acid;
piperidines		00low000000
1-(3-phenylpropanoyl)-4-piperidinecarboxylic acid
0
carboxylic acid;
piperidines		00low000000
1-[2-hydroxy-3-[4-(2-methylbutan-2-yl)phenoxy]propyl]-4-piperidinecarboxylic acid ethyl ester
0
carboxylic acid;
piperidines		00low000000
1-[2-[(4-chlorophenyl)thio]-1-oxopropyl]-4-piperidinecarboxylic acid ethyl ester
0
carboxylic acid;
piperidines		00low000000
1-[2-[3-(N-ethylanilino)propylamino]-3,4-dioxo-1-cyclobutenyl]-4-piperidinecarboxylic acid ethyl ester
0
carboxylic acid;
piperidines		00low000000
4-[[2-(3-ethylanilino)-3,4-dioxo-1-cyclobutenyl]amino]-1-piperidinecarboxylic acid ethyl ester
0
carboxylic acid;
piperidines		00low000000
1-[(6-hydroxy-2-methyl-5-thiazolo[3,2-b][1,2,4]triazolyl)-(3,4,5-trimethoxyphenyl)methyl]-4-piperidinecarboxylic acid methyl ester
0
carboxylic acid;
piperidines		00low000000
rifamycin b
0
acetate ester;
carboxylic acid;
organic heterotetracyclic compound;
rifamycins		00low000000
pradimicin a
0
aromatic ether;
carboxylic acid;
disaccharide derivative;
L-alanine derivative;
p-quinones;
polyphenol;
pradimicin;
secondary alcohol		00low000000
cinalukast
0
1,3-thiazoles;
carboxylic acid		anti-arrhythmia drug;
anti-asthmatic drug;
leukotriene antagonist		00low000000
u 62840
0
carbotricyclic compound;
carboxylic acid		antihypertensive agent;
cardiovascular drug;
human blood serum metabolite;
platelet aggregation inhibitor;
vasodilator agent;
vitamin K antagonist		00low000000
tubulysin a
0
carboxylic acid;
diester		00low000000
tubulysin d
0
carboxylic acid;
diester		00low000000
4-[[3-(4-chlorophenyl)-5-isoxazolyl]methyl]-1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-piperidinecarboxylic acid
0
carboxylic acid;
piperidines		00low000000
ethyl 1-benzyl-3-hydroxy-2(5h)-oxopyrrole-4-carboxylate
0
carboxylic acid;
pyrroline		00low000000
albendazole
0
aryl sulfide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester		anthelminthic drug;
microtubule-destabilising agent;
tubulin modulator		00low000000
bendiocarb
0
benzodioxoles;
carbamate ester		agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor		00low000000
bethanechol
0
carbamate ester;
quaternary ammonium ion		muscarinic agonist00low000000
carbofuran
0
1-benzofurans;
carbamate ester		acaricide;
agrochemical;
avicide;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
nematicide		00low000000
carisoprodol
0
carbamate estermuscle relaxant00low000000
chlorphenesin carbamate
0
carbamate ester;
monochlorobenzenes;
secondary alcohol		muscle relaxant00low000000
chlorpropham
0
benzenes;
carbamate ester;
monochlorobenzenes		herbicide;
plant growth retardant		00low000000
distigmine
0
carbamate ester;
pyridinium ion		EC 3.1.1.8 (cholinesterase) inhibitor;
muscarinic agonist		00low000000
ethinamate
0
carbamate ester;
terminal acetylenic compound		sedative00low000000
felbamate
0
carbamate esteranticonvulsant;
neuroprotective agent		00low000000
fenbendazole
0
aryl sulfide;
benzimidazoles;
carbamate ester		antinematodal drug00low000000
mebendazole
0
aromatic ketone;
benzimidazoles;
carbamate ester		antinematodal drug;
microtubule-destabilising agent;
tubulin modulator		00low000000
methocarbamol
0
aromatic ether;
carbamate ester;
secondary alcohol		00low000000
methomyl
0
aliphatic sulfide;
carbamate ester		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
nematicide;
xenobiotic		00low000000
nocodazole
0
aromatic ketone;
benzimidazoles;
carbamate ester;
thiophenes		antimitotic;
antineoplastic agent;
microtubule-destabilising agent;
tubulin modulator		00low000000
entinostat
0
benzamides;
carbamate ester;
primary amino compound;
pyridines;
substituted aniline		antineoplastic agent;
apoptosis inducer;
EC 3.5.1.98 (histone deacetylase) inhibitor		00low000000
oxibendazole
0
benzimidazoles;
carbamate ester		00low000000
phosalone
0
1,3-benzoxazoles;
carbamate ester;
organochlorine insecticide;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor		00low000000
propoxur
0
aromatic ether;
carbamate ester		acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor		00low000000
1,6-bis(cyclohexyloximinocarbonyl)hexane
0
carbamate ester;
organonitrogen compound		00low000000
ronidazole
0
C-nitro compound;
carbamate ester;
imidazoles		antiparasitic agent;
antiprotozoal drug		00low000000
urethane
0
carbamate esterfungal metabolite;
mutagen		00low000000
ici 204,219
0
carbamate ester;
indoles;
N-sulfonylcarboxamide		anti-asthmatic agent;
leukotriene antagonist		00low000000
carbachol
0
ammonium salt;
carbamate ester		cardiotonic drug;
miotic;
muscarinic agonist;
nicotinic acetylcholine receptor agonist;
non-narcotic analgesic		00low000000
demecarium
0
carbamate ester;
quaternary ammonium ion		00low000000
physostigmine
0
carbamate ester;
indole alkaloid		antidote to curare poisoning;
EC 3.1.1.8 (cholinesterase) inhibitor;
miotic		00low000000
carbaryl
0
carbamate ester;
naphthalenes		acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
plant growth retardant		00low000000
emylcamate
0
carbamate ester00low000000
barban
0
acetylenic compound;
carbamate ester;
monochlorobenzenes		herbicide00low000000
hexapropymate
0
carbamate ester00low000000
diperodon
0
carbamate ester00low000000
uraline
0
carbamate ester00low000000
bethanechol chloride
0
carbamate ester;
chloride salt;
quaternary ammonium salt		muscarinic agonist00low000000
methyl carbamate
0
carbamate ester00low000000
metolcarb
0
carbamate esteracaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor		00low000000
aminocarb
0
carbamate ester;
toluenes		acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
molluscicide		00low000000
methiocarb
0
aryl sulfide;
carbamate ester;
methyl sulfide		acaricide;
agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide;
molluscicide;
xenobiotic		00low000000
mecarbam
0
carbamate ester;
organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor		00low000000
isoprocarb
0
carbamate esteragrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor		00low000000
methiocarb sulfoxide
0
carbamate ester;
sulfoxide		marine xenobiotic metabolite00low000000
asulam
0
carbamate ester;
primary amino compound;
substituted aniline;
sulfonamide		agrochemical;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
herbicide;
xenobiotic		00low000000
bpmc
0
carbamate esteragrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
herbicide;
insecticide		00low000000
tybamate
0
carbamate ester00low000000
lobendazole
0
benzimidazoles;
carbamate ester		00low000000
nitrosocarbaryl
0
carbamate ester;
naphthalenes;
nitroso compound		carcinogenic agent;
mutagen		00low000000
propham
0
benzenes;
carbamate ester		herbicide;
plant growth retardant		00low000000
desmedipham
0
carbamate esteragrochemical;
environmental contaminant;
herbicide;
xenobiotic		00low000000
phenmedipham
0
carbamate esterenvironmental contaminant;
herbicide;
xenobiotic		00low000000
carbendazim
0
benzimidazole fungicide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester		antifungal agrochemical;
antinematodal drug;
metabolite;
microtubule-destabilising agent		00low000000
parbendazole
0
benzimidazoles;
carbamate ester		00low000000
vinyl carbamate
0
carbamate ester00low000000
metergoline
0
carbamate ester;
ergoline alkaloid		dopamine agonist;
geroprotector;
serotonergic antagonist		00low000000
benomyl
0
aromatic amide;
benzimidazole fungicide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester		acaricide;
anthelminthic drug;
antifungal agrochemical;
microtubule-destabilising agent;
tubulin modulator		00low000000
carbimazole
0
1,3-dihydroimidazole-2-thiones;
carbamate ester		antithyroid drug;
prodrug		00low000000
formetanate
0
carbamate esteracaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor		00low000000
pirimicarb
0
aminopyrimidine;
carbamate ester;
tertiary amino compound		agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic		00low000000
propamocarb
0
carbamate ester;
carbamate fungicide;
tertiary amino compound		antifungal agrochemical;
environmental contaminant;
xenobiotic		00low000000
moricizine
0
carbamate ester;
morpholines;
phenothiazines		anti-arrhythmia drug00low000000
croneton
0
carbamate esteragrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor		00low000000
flubendazole
0
aromatic ketone;
benzimidazoles;
carbamate ester;
organofluorine compound		antinematodal drug;
teratogenic agent		00low000000
ciclobendazole
0
benzimidazoles;
carbamate ester		00low000000
oxfendazole
0
benzimidazoles;
carbamate ester;
sulfoxide		antinematodal drug00low000000
dibutylaminosulfenylcarbofuran
0
1-benzofurans;
carbamate ester		acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
nematicide		00low000000
diaziquone
0
1,4-benzoquinones;
aziridines;
carbamate ester;
enamine		alkylating agent;
antineoplastic agent		00low000000
deltanit
0
1-benzofurans;
carbamate ester		agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor		00low000000
fenoxycarb
0
aromatic ether;
carbamate ester		environmental contaminant;
insecticide;
juvenile hormone mimic;
xenobiotic		00low000000
bambuterol hydrochloride
0
carbamate ester;
hydrochloride;
phenylethanolamines		anti-asthmatic drug;
beta-adrenergic agonist;
bronchodilator agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
prodrug;
sympathomimetic agent		00low000000
bambuterol
0
carbamate ester;
phenylethanolamines		anti-asthmatic drug;
beta-adrenergic agonist;
bronchodilator agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
prodrug;
sympathomimetic agent;
tocolytic agent		00low000000
benfuracarb
0
1-benzofurans;
carbamate ester;
ethyl ester		agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor		00low000000
irinotecan
0
carbamate ester;
delta-lactone;
N-acylpiperidine;
pyranoindolizinoquinoline;
ring assembly;
tertiary alcohol;
tertiary amino compound		antineoplastic agent;
apoptosis inducer;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
prodrug		00low000000
capecitabine
0
carbamate ester;
cytidines;
organofluorine compound		antimetabolite;
antineoplastic agent;
prodrug		00low000000
3-iodo-2-propynylbutylcarbamate
0
acetylenic compound;
carbamate ester;
carbamate fungicide;
organoiodine compound		antifungal agrochemical;
environmental contaminant;
xenobiotic		00low000000
amprenavir
0
carbamate ester;
sulfonamide;
tetrahydrofuryl ester		antiviral drug;
HIV protease inhibitor		00low000000
cyclarbamate
0
carbamate ester00low000000
carbobenzoxyvalylphenylalanine aldehyde
0
aldehyde;
carbamate ester;
dipeptide		antileishmanial agent;
apoptosis inhibitor;
EC 3.4.22.52 (calpain-1) inhibitor;
EC 3.4.22.53 (calpain-2) inhibitor;
EC 3.4.23.46 (memapsin 2) inhibitor		00low000000
oxazolidin-2-one
0
carbamate ester;
oxazolidinone		metabolite00low000000
rivastigmine
0
carbamate ester;
tertiary amino compound		cholinergic drug;
EC 3.1.1.8 (cholinesterase) inhibitor;
neuroprotective agent		00low000000
diethofencarb
0
aromatic ether;
carbamate ester;
carbanilate fungicide		antifungal agrochemical00low000000
ezogabine
0
carbamate ester;
organofluorine compound;
secondary amino compound;
substituted aniline		anticonvulsant;
potassium channel modulator		00low000000
thiobenzyl benzyloxycarbonyl-l-lysinate
0
benzyl ester;
carbamate ester;
L-lysine derivative;
primary amino compound;
thiocarboxylic ester		00low000000
torcetrapib
0
(trifluoromethyl)benzenes;
carbamate ester;
quinolines		anticholesteremic drug;
CETP inhibitor		00low000000
N-(4-methoxyphenyl)carbamic acid propan-2-yl ester
0
carbamate ester00low000000
darunavir
0
carbamate ester;
furofuran;
sulfonamide		antiviral drug;
HIV protease inhibitor		00low000000
N-(3-chlorophenyl)carbamic acid 2-pyridinylmethyl ester
0
carbamate ester00low000000
N-[3-(ethoxycarbonylamino)-2,2-dimethylpropyl]carbamic acid ethyl ester
0
carbamate ester00low000000
nsc-89199
0
carbamate ester;
organochlorine compound;
steroid phosphate		00low000000
estramustine
0
17beta-hydroxy steroid;
carbamate ester;
organochlorine compound		alkylating agent;
antineoplastic agent;
radiation protective agent		00low000000
N-(4-fluorophenyl)carbamic acid (2-oxo-1H-pyridin-3-yl) ester
0
carbamate ester00low000000
N-phenylcarbamic acid 2-phenoxyethyl ester
0
carbamate ester00low000000
o-(chloroacetylcarbamoyl)fumagillol
0
carbamate ester;
organochlorine compound;
semisynthetic derivative;
sesquiterpenoid;
spiro-epoxide		angiogenesis inhibitor;
antineoplastic agent;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
methionine aminopeptidase 2 inhibitor;
retinoic acid receptor alpha antagonist		00low000000
ritonavir
0
1,3-thiazoles;
carbamate ester;
carboxamide;
L-valine derivative;
ureas		antiviral drug;
environmental contaminant;
HIV protease inhibitor;
xenobiotic		00low000000
benzyloxycarbonylleucyl-leucyl-leucine aldehyde
0
amino aldehyde;
carbamate ester;
tripeptide		proteasome inhibitor00low000000
N-[2-[(3-chloroanilino)-oxomethoxy]ethyl]carbamic acid propan-2-yl ester
0
carbamate ester00low000000
N-[4-(2-pyrimidinylsulfamoyl)phenyl]carbamic acid methyl ester
0
carbamate ester00low000000
N-(4-phenylmethoxyphenyl)carbamic acid methyl ester
0
carbamate ester00low000000
N-methyl-N-phenylcarbamic acid (4-tert-butylphenyl) ester
0
carbamate ester00low000000
ethyl 4-{N-[(4-chlorophenyl)sulfonyl]-N-methylglycyl}piperazine-1-carboxylate
0
carbamate ester;
sulfonamide		00low000000
N-(4-chlorophenyl)carbamic acid 2-pyridinylmethyl ester
0
carbamate ester00low000000
N-(4-chlorophenyl)carbamic acid [1-(4-chlorophenyl)-4-triazolyl]methyl ester
0
carbamate ester00low000000
N-phenylcarbamic acid [5-(2-chlorophenyl)-3-isoxazolyl]methyl ester
0
carbamate ester00low000000
3,3,3-trifluoro-2-hydroxy-2-[4-[methoxycarbonyl(methyl)amino]phenyl]propanoic acid methyl ester
0
carbamate ester00low000000
thiophanate
0
benzimidazole precursor fungicide;
carbamate ester;
carbamate fungicide;
thioureas		antifungal agrochemical00low000000
thiophanate
0
benzimidazole precursor fungicide;
carbamate ester;
carbamate fungicide;
thioureas		antifungal drug00low000000
maytansine
0
alpha-amino acid ester;
carbamate ester;
epoxide;
maytansinoid;
organic heterotetracyclic compound;
organochlorine compound		antimicrobial agent;
antimitotic;
antineoplastic agent;
plant metabolite;
tubulin modulator		00low000000
geldanamycin
0
1,4-benzoquinones;
ansamycin;
carbamate ester;
organic heterobicyclic compound		antimicrobial agent;
antineoplastic agent;
antiviral agent;
cysteine protease inhibitor;
Hsp90 inhibitor		00low000000
17-(dimethylaminoethylamino)-17-demethoxygeldanamycin
0
1,4-benzoquinones;
ansamycin;
carbamate ester;
secondary amino compound;
tertiary amino compound		Hsp90 inhibitor00low000000
l 685458
0
carbamate ester;
monocarboxylic acid amide;
peptide;
secondary alcohol		EC 3.4.23.46 (memapsin 2) inhibitor;
peptidomimetic		00low000000
z-val-ala-asp(ome)-fluoromethylketone
0
carbamate ester;
organofluorine compound;
tripeptide		apoptosis inhibitor;
protease inhibitor		00low000000
pyrachlostrobin
0
aromatic ether;
carbamate ester;
carbanilate fungicide;
methoxycarbanilate strobilurin antifungal agent;
monochlorobenzenes;
pyrazoles		antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
xenobiotic		00low000000
concanamycin a
0
carbamate ester;
concanamycin		antifungal agent;
EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor;
metabolite		00low000000
kalimantacin a
0
alpha,beta-unsaturated monocarboxylic acid;
carbamate ester;
fatty acid derivative;
secondary carboxamide		antibacterial agent;
antimicrobial agent;
bacterial metabolite		00low000000
tanespimycin
0
1,4-benzoquinones;
ansamycin;
carbamate ester;
organic heterobicyclic compound;
secondary amino compound		antineoplastic agent;
apoptosis inducer;
Hsp90 inhibitor		00low000000
methiazole
0
benzimidazoles;
carbamate ester		00low000000
iprovalicarb
0
amino acid amide;
carbamate ester;
valine derivative		00low000000
givinostat
0
carbamate ester00low000000
cay 10499
0
carbamate ester00low000000
vorapaxar
0
carbamate ester;
lactone;
naphthofuran;
organofluorine compound;
pyridines		cardiovascular drug;
platelet aggregation inhibitor;
protease-activated receptor-1 antagonist		00low000000
ki16425
0
carbamate ester;
isoxazoles;
monocarboxylic acid;
monochlorobenzenes;
organic sulfide		00low000000
tedizolid
0
carbamate ester;
organofluorine compound;
oxazolidinone;
primary alcohol;
pyridines;
tetrazoles		antimicrobial agent;
drug metabolite;
protein synthesis inhibitor		00low000000
bay 63-2521
0
aminopyrimidine;
carbamate ester;
organofluorine compound;
pyrazolopyridine		antihypertensive agent;
soluble guanylate cyclase activator		00low000000
tedizolid phosphate
0
carbamate ester;
organofluorine compound;
oxazolidinone;
phosphate monoester;
pyridines;
tetrazoles		antimicrobial agent;
prodrug;
protein synthesis inhibitor		00low000000
bay 60-4552
0
aminopyrimidine;
carbamate ester;
monofluorobenzenes;
pyrazolopyridine		antihypertensive agent;
drug metabolite;
soluble guanylate cyclase activator;
vasodilator agent		00low000000
wyosine
0
carbamate ester;
methyl ester;
nucleoside analogue		00low000000
mk-7009
0
azamacrocycle;
carbamate ester;
cyclopropanes;
N-sulfonylcarboxamide;
pyrrolidinecarboxamide		antiviral drug;
hepatitis C protease inhibitor		00low000000
N-[4-[3-[[[7-(hydroxyamino)-7-oxoheptyl]amino]-oxomethyl]-5-isoxazolyl]phenyl]carbamic acid tert-butyl ester
0
carbamate ester00low000000
cobicistat
0
1,3-thiazoles;
carbamate ester;
monocarboxylic acid amide;
morpholines;
ureas		P450 inhibitor00low000000
bms-790052
0
biphenyls;
carbamate ester;
carboxamide;
imidazoles;
valine derivative		antiviral drug;
nonstructural protein 5A inhibitor		00low000000
4-[6-[4-(methoxycarbonylamino)phenyl]-4-(4-morpholinyl)-1-pyrazolo[3,4-d]pyrimidinyl]-1-piperidinecarboxylic acid methyl ester
0
carbamate ester00low000000
grazoprevir
0
aromatic ether;
azamacrocycle;
carbamate ester;
cyclopropanes;
lactam;
N-sulfonylcarboxamide;
quinoxaline derivative		antiviral drug;
hepatitis C protease inhibitor;
hepatoprotective agent		00low000000
vericiguat
0
aminopyrimidine;
carbamate ester;
organofluorine compound;
pyrazolopyridine		antihypertensive agent;
soluble guanylate cyclase activator;
vasodilator agent		00low000000
novobiocin
0
carbamate ester;
ether;
hexoside;
hydroxycoumarin;
monocarboxylic acid amide;
monosaccharide derivative;
phenols		antibacterial agent;
antimicrobial agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
Escherichia coli metabolite;
hepatoprotective agent		00low000000
abt-267
0
aromatic amide;
carbamate ester;
dipeptide;
pyrrolidines		antiviral drug;
hepatitis C virus nonstructural protein 5A inhibitor		00low000000
saxitoxin
0
alkaloid;
carbamate ester;
guanidines;
ketone hydrate;
paralytic shellfish toxin;
pyrrolopurine		cyanotoxin;
marine metabolite;
neurotoxin;
sodium channel blocker;
toxin		00low000000
ledipasvir
0
azaspiro compound;
benzimidazole;
bridged compound;
carbamate ester;
carboxamide;
fluorenes;
imidazoles;
L-valine derivative;
N-acylpyrrolidine;
organofluorine compound		antiviral drug;
hepatitis C protease inhibitor		00low000000
gs-5816
0
carbamate ester;
ether;
imidazoles;
L-valine derivative;
N-acylpyrrolidine;
organic heteropentacyclic compound;
ring assembly		antiviral drug;
hepatitis C virus nonstructural protein 5A inhibitor		00low000000
mk-8742
0
carbamate ester;
imidazoles;
L-valine derivative;
N-acylpyrrolidine;
organic heterotetracyclic compound;
ring assembly		antiviral drug;
hepatitis C virus nonstructural protein 5A inhibitor;
hepatoprotective agent		00low000000
crotamiton
0
enamide;
tertiary carboxamide		antipruritic drug;
scabicide		00low000000
carboxin
0
anilide fungicide;
anilide;
enamide;
organosulfur heterocyclic compound;
oxacycle;
secondary carboxamide		antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor		00low000000
ag-490
0
catechols;
enamide;
monocarboxylic acid amide;
nitrile;
secondary carboxamide		anti-inflammatory agent;
antioxidant;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector;
STAT3 inhibitor		00low000000
pipercallosidine
0
alkaloid;
benzodioxoles;
enamide;
secondary carboxamide		apoptosis inducer;
metabolite;
plant metabolite		00low000000
streptogramin a
0
1,3-oxazoles;
cyclic ketone;
enamide;
lactam;
macrolide antibiotic;
macrolide;
pyrroline;
secondary alcohol;
secondary carboxamide;
tertiary carboxamide		antibacterial drug;
Mycoplasma genitalium metabolite		00low000000
dimethomorph
0
aromatic ether;
enamide;
monochlorobenzenes;
morpholine fungicide;
tertiary carboxamide		00low000000
su 1498
0
enamide;
monocarboxylic acid amide;
nitrile;
phenols;
secondary carboxamide		vascular endothelial growth factor receptor antagonist00low000000
tyrphostin ag825
0
aromatic ether;
benzothiazoles;
enamide;
nitrile;
organic sulfide;
phenols;
primary carboxamide		epidermal growth factor receptor antagonist00low000000
manumycin
0
enamide;
epoxide;
organic heterobicyclic compound;
polyketide;
secondary carboxamide;
tertiary alcohol		antiatherosclerotic agent;
antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
bacterial metabolite;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.5.1.58 (protein farnesyltransferase) inhibitor;
marine metabolite		00low000000
asukamycin
0
enamide;
epoxide;
organic heterobicyclic compound;
polyketide;
secondary carboxamide;
tertiary alcohol		antibacterial agent;
antifungal agent;
antimicrobial agent;
antineoplastic agent;
bacterial metabolite		00low000000
SIS3 free base
0
aromatic ether;
enamide;
isoquinolines;
monocarboxylic acid amide;
pyrrolopyridine;
tertiary carboxamide		Smad3 inhibitor00low000000
bibw 2992
0
aromatic ether;
enamide;
furans;
monochlorobenzenes;
organofluorine compound;
quinazolines;
secondary carboxamide;
tertiary amino compound		antineoplastic agent;
tyrosine kinase inhibitor		00low000000
bl1521
0
enamide;
hydroxamic acid;
monocarboxylic acid amide		antineoplastic agent;
apoptosis inducer;
EC 3.5.1.98 (histone deacetylase) inhibitor		00low000000
pha 665752
0
dichlorobenzene;
enamide;
indolones;
N-acylpyrrolidine;
pyrrolecarboxamide;
secondary carboxamide;
sulfone;
tertiary carboxamide		antineoplastic agent;
c-Met tyrosine kinase inhibitor		00low000000
flumorph
0
aromatic ether;
enamide;
morpholines;
organofluorine compound;
tertiary carboxamide		00low000000
pf 00299804
0
enamide;
monochlorobenzenes;
monofluorobenzenes;
piperidines;
quinazolines;
secondary amino compound;
secondary carboxamide;
tertiary amino compound		antineoplastic agent;
epidermal growth factor receptor antagonist		00low000000
lfm a13
0
aromatic amide;
dibromobenzene;
enamide;
enol;
nitrile;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 2.7.11.21 (polo kinase) inhibitor;
geroprotector;
platelet aggregation inhibitor		00low000000
teriflunomide
0
(trifluoromethyl)benzenes;
aromatic amide;
enamide;
enol;
nitrile;
secondary carboxamide		drug metabolite;
EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor;
hepatotoxic agent;
non-steroidal anti-inflammatory drug;
tyrosine kinase inhibitor		00low000000
THZ531
0
aminopyrimidine;
enamide;
indoles;
N-acylpiperidine;
organochlorine compound;
secondary amino compound;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor		00low000000
2-(4-methyl-1,3-thiazol-5-yl)ethanol
0
1,3-thiazoles;
primary alcohol		Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite		00low000000
2-aminothiazole
0
1,3-thiazoles;
primary amino compound		00low000000
famotidine
0
1,3-thiazoles;
guanidines;
sulfonamide		anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor		00low000000
nizatidine
0
1,3-thiazoles;
C-nitro compound;
carboxamidine;
organic sulfide;
tertiary amino compound		anti-ulcer drug;
cholinergic drug;
H2-receptor antagonist		00low000000
phthalylsulfathiazole
0
1,3-thiazoles;
dicarboxylic acid monoamide;
sulfonamide antibiotic;
sulfonamide		00low000000
succinylsulfathiazole
0
1,3-thiazoles00low000000
sulfathiazole
0
1,3-thiazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
xenobiotic		00low000000
thiabendazole
0
1,3-thiazoles;
benzimidazole fungicide;
benzimidazoles		antifungal agrochemical;
antinematodal drug		00low000000
niridazole
0
1,3-thiazoles;
C-nitro compound		00low000000
thiazoles
0
1,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene		00low000000
4-methylthiazole
0
1,3-thiazolesMaillard reaction product00low000000
2-aminothiazoline
0
1,3-thiazoles;
primary amino compound		00low000000
2-amino-delta(2)-thiazoline-4-carboxylic acid
0
1,3-thiazoles;
amino acid zwitterion;
sulfur-containing amino acid		00low000000
2-(alpha-thenoylamino)-2-nitro-5-thiazole
0
1,3-thiazoles;
C-nitro compound		00low000000
2-isobutyl-1,3-thiazole
0
1,3-thiazolesflavouring agent;
Maillard reaction product;
pheromone		00low000000
N(4)-acetylsulfathiazole
0
1,3-thiazoles;
acetamides;
sulfonamide		marine xenobiotic metabolite00low000000
disperse blue 124
0
1,3-thiazoles;
monoazo compound;
tertiary amine		allergen;
dye;
hapten		00low000000
thifluzamide
0
1,3-thiazoles;
anilide fungicide;
aromatic amide;
aromatic ether;
dibromobenzene;
organofluorine compound		antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor		00low000000
2-(2-aminoethyl)thiazole
0
1,3-thiazoles00low000000
thiamethoxam
0
1,3-thiazoles;
2-nitroguanidine derivative;
organochlorine compound;
oxadiazane		antifeedant;
carcinogenic agent;
environmental contaminant;
neonicotinoid insectide;
xenobiotic		00low000000
xv 638
0
1,3-thiazoles;
benzamides;
diazepanone;
diol;
secondary alcohol;
secondary carboxamide;
ureas		HIV protease inhibitor00low000000
tiazofurin
0
1,3-thiazoles;
C-glycosyl compound;
monocarboxylic acid amide		antineoplastic agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
prodrug		00low000000
ravuconazole
0
1,3-thiazoles;
fluorobenzenes;
nitrile;
tertiary alcohol;
triazoles		antifungal drug;
antileishmanial agent;
EC 1.14.14.154 (sterol 14alpha-demethylase) inhibitor;
ergosterol biosynthesis inhibitor		00low000000
camalexin
0
1,3-thiazoles;
indole phytoalexin		metabolite00low000000
1-(4-chlorophenyl)-3-[4-methyl-2-(thiophen-2-yl)-1,3-thiazol-5-yl]urea
0
1,3-thiazoles;
monochlorobenzenes;
phenylureas;
thiophenes		00low000000
bms 387032
0
1,3-oxazoles;
1,3-thiazoles;
organic sulfide;
piperidinecarboxamide;
secondary carboxamide		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor		00low000000
dasatinib
0
1,3-thiazoles;
aminopyrimidine;
monocarboxylic acid amide;
N-(2-hydroxyethyl)piperazine;
N-arylpiperazine;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antineoplastic agent;
tyrosine kinase inhibitor		00low000000
cefteram pivoxil
0
1,3-thiazoles;
cephams;
oxime O-ether;
pivaloyloxymethyl ester;
tetrazoles		00low000000
cystothiazole a
0
1,3-thiazoles;
biaryl;
enoate ester;
enol ether;
methyl ester;
organonitrogen heterocyclic antibiotic		antifungal agent;
antineoplastic agent;
bacterial metabolite		00low000000
cefetamet pivoxyl
0
1,3-thiazoles;
cephams;
oxime O-ether;
pivaloyloxymethyl ester		00low000000
famotidine
0
1,3-thiazoles;
guanidines;
sulfonamide		anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor		00low000000
apratoxin a
0
1,3-thiazoles;
apratoxin		antineoplastic agent;
metabolite		00low000000
cefditoren pivoxil
0
1,3-thiazoles;
cephams;
oxime O-ether;
pivaloyloxymethyl ester		antibacterial drug;
prodrug		00low000000
ixabepilone
0
1,3-thiazoles;
beta-hydroxy ketone;
epoxide;
lactam;
macrocycle		antineoplastic agent;
microtubule-destabilising agent		00low000000
isavuconazole
0
1,3-thiazoles;
conazole antifungal drug;
difluorobenzene;
nitrile;
tertiary alcohol;
triazole antifungal drug		EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
ergosterol biosynthesis inhibitor;
orphan drug		00low000000
gw 501516
0
1,3-thiazoles;
aromatic ether;
aryl sulfide;
monocarboxylic acid;
organofluorine compound		carcinogenic agent;
PPARbeta/delta agonist		00low000000
dolastatin 10
0
1,3-thiazoles;
tetrapeptide		animal metabolite;
antineoplastic agent;
apoptosis inducer;
marine metabolite;
microtubule-destabilising agent		00low000000
mirabegron
0
1,3-thiazoles;
aromatic amide;
ethanolamines;
monocarboxylic acid amide		beta-adrenergic agonist00low000000
dysidenin
0
1,3-thiazoles;
organochlorine compound;
secondary carboxamide;
tertiary carboxamide		animal metabolite;
marine metabolite;
toxin		00low000000
pateamine a
0
1,3-thiazoles;
macrodiolide;
olefinic compound;
primary amino compound;
tertiary amino compound		antineoplastic agent;
antiviral agent;
eukaryotic initiation factor 4F inhibitor;
marine metabolite		00low000000
masitinib
0
1,3-thiazoles;
benzamides;
N-alkylpiperazine;
pyridines		antineoplastic agent;
antirheumatic drug;
tyrosine kinase inhibitor		00low000000
ethaboxam
0
1,3-thiazoles;
aromatic amide;
aromatic amine;
nitrile;
secondary amino compound;
thiophenes		00low000000
ym 216391
0
1,3-oxazoles;
1,3-thiazoles;
azamacrocycle;
benzenes;
heterodetic cyclic peptide		antineoplastic agent;
bacterial metabolite		00low000000
fluensulfone
0
1,3-thiazoles;
olefinic compound;
organochlorine pesticide;
organofluorine pesticide;
sulfone		agrochemical;
nematicide		00low000000
5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine
0
1,3-thiazoles;
C-nitro compound;
organic sulfide;
primary amino compound;
thiadiazoles		antibacterial agent;
c-Jun N-terminal kinase inhibitor		00low000000
lcl161
0
1,3-thiazoles;
aromatic ketone;
L-alanine derivative;
monofluorobenzenes;
N-acylpyrrolidine		antineoplastic agent;
apoptosis inducer		00low000000
cyclopentylidene-[4-(4-chlorophenyl)thiazol-2-yl]hydrazone
0
1,3-thiazoles;
hydrazone;
monochlorobenzenes		EC 2.3.1.48 (histone acetyltransferase) inhibitor00low000000
dabrafenib
0
1,3-thiazoles;
aminopyrimidine;
organofluorine compound;
sulfonamide		anticoronaviral agent;
antineoplastic agent;
B-Raf inhibitor		00low000000
mobic
0
1,3-thiazoles;
benzothiazine;
monocarboxylic acid amide		analgesic;
antirheumatic drug;
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug		00low000000
oxathiapiprolin
0
1,3-thiazoles;
isoxazoline;
N-acylpiperidine;
organofluorine compound;
pyrazoles;
tertiary carboxamide		00low000000
LimKi 3
0
1,3-thiazoles;
dichlorobenzene;
organofluorine compound;
pyrazoles;
secondary carboxamide		LIM kinase inhibitor00low000000
clothianidin
0
1,3-thiazoles;
2-nitroguanidine derivative;
clothianidin;
organochlorine compound		environmental contaminant;
neonicotinoid insectide;
nicotinic acetylcholine receptor agonist;
xenobiotic		00low000000
althiomycin
0
1,3-thiazoles;
aldoxime;
ether;
gamma-lactam;
pentapeptide;
peptide antibiotic;
primary alcohol;
pyrroline;
secondary carboxamide;
tertiary carboxamide		antibacterial agent;
bacterial metabolite;
protein synthesis inhibitor		00low000000
clothianidin
0
1,3-thiazoles;
2-nitroguanidine derivative;
clothianidin;
organochlorine compound		environmental contaminant;
neonicotinoid insectide;
nicotinic acetylcholine receptor agonist;
xenobiotic		00low000000
colibactin
0
1,3-thiazoles;
azaspiro compound;
polyketide;
pyrroline;
secondary carboxamide		alkylating agent;
carcinogenic agent;
Escherichia coli metabolite;
genotoxin		00low000000
butoctamide succinate
0
dicarboxylic acid monoester;
hemisuccinate;
secondary carboxamide		00low000000
cl 387785
0
bromobenzenes;
quinazolines;
secondary carboxamide;
ynamide		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
epidermal growth factor receptor antagonist		00low000000
iodipamide
0
benzoic acids;
organoiodine compound;
secondary carboxamide		radioopaque medium00low000000
4-(dimethylamino)-n-(7-(hydroxyamino)-7-oxoheptyl)benzamide
0
benzamides;
hydroxamic acid;
secondary carboxamide;
tertiary amino compound		antineoplastic agent;
apoptosis inducer;
EC 3.5.1.98 (histone deacetylase) inhibitor		00low000000
nemonapride
0
benzamides;
monochlorobenzenes;
monomethoxybenzene;
N-alkylpyrrolidine;
secondary amino compound;
secondary carboxamide;
substituted aniline		00low000000
niclosamide
0
benzamides;
C-nitro compound;
monochlorobenzenes;
salicylanilides;
secondary carboxamide		anthelminthic drug;
anticoronaviral agent;
antiparasitic agent;
apoptosis inducer;
molluscicide;
piscicide;
STAT3 inhibitor		00low000000
pd168393
0
acrylamides;
bromobenzenes;
quinazolines;
secondary carboxamide;
substituted aniline		epidermal growth factor receptor antagonist00low000000
pilsicainide
0
organic heterobicyclic compound;
secondary carboxamide		anti-arrhythmia drug;
sodium channel blocker		00low000000
pj-34
0
phenanthridines;
secondary carboxamide;
tertiary amino compound		angiogenesis inhibitor;
anti-inflammatory agent;
antiatherosclerotic agent;
antineoplastic agent;
apoptosis inducer;
cardioprotective agent;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
neuroprotective agent		00low000000
opc 12759
0
secondary carboxamide00low000000
suramin
0
naphthalenesulfonic acid;
phenylureas;
secondary carboxamide		angiogenesis inhibitor;
antinematodal drug;
antineoplastic agent;
apoptosis inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
GABA antagonist;
GABA-gated chloride channel antagonist;
purinergic receptor P2 antagonist;
ryanodine receptor agonist;
trypanocidal drug		00low000000
2-[[3-(3,4-dimethoxyphenyl)-1-oxoprop-2-enyl]amino]benzoic acid
0
amidobenzoic acid;
cinnamamides;
secondary carboxamide		00low000000
acedapsone
0
acetamides;
anilide;
secondary carboxamide;
sulfone		antimalarial;
antimicrobial drug		00low000000
salicylurate
0
N-acylglycine;
secondary carboxamide		human xenobiotic metabolite;
uremic toxin		00low000000
monoacetyldapsone
0
acetamides;
anilide;
secondary carboxamide;
sulfone		00low000000
n-methylolacrylamide
0
secondary carboxamide00low000000
win 18446
0
organochlorine compound;
secondary carboxamide		EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor00low000000
tromantadine
0
secondary carboxamide00low000000
aureothricin
0
dithiolopyrrolone antibiotic;
secondary carboxamide		angiogenesis inhibitor;
antibacterial agent;
bacterial metabolite;
EC 2.7.7.6 (RNA polymerase) inhibitor		00low000000
morphazinamide
0
morpholines;
pyrazines;
secondary carboxamide		00low000000
amperozide
0
diarylmethane;
monofluorobenzenes;
N-alkylpiperazine;
secondary carboxamide;
ureas		anxiolytic drug;
dopamine uptake inhibitor;
geroprotector;
second generation antipsychotic;
serotonergic antagonist		00low000000
n-acetyltryptophanamide
0
acetamides;
L-tryptophan derivative;
primary carboxamide;
secondary carboxamide		00low000000
gamma-glutamyltyrosine
0
dicarboxylic acid;
dipeptide;
phenols;
primary amino compound;
secondary carboxamide		human metabolite00low000000
n-acetyldopamine
0
acetamides;
catechols;
N-(fatty acyl)-dopamine;
secondary carboxamide		human urinary metabolite;
marine metabolite		00low000000
n-acetylcytidine
0
acetamides;
cytidines;
secondary carboxamide		metabolite00low000000
florfenicol
0
organochlorine compound;
organofluorine compound;
secondary alcohol;
secondary carboxamide;
sulfone		antimicrobial agent00low000000
marimastat
0
hydroxamic acid;
secondary carboxamide		antineoplastic agent;
matrix metalloproteinase inhibitor		00low000000
n-(3-oxohexanoyl)-3-aminodihydro-2(3h)-furanone
0
N-acyl homoserine lactone;
secondary carboxamide		00low000000
mosapride
0
aromatic ether;
benzamides;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
secondary carboxamide;
substituted aniline;
tertiary amino compound		00low000000
benzyloxycarbonylphenylalanylphenylalanine diazomethyl ketone
0
carboxylic ester;
diazo compound;
L-phenylalanine derivative;
secondary carboxamide		cathepsin L (EC 3.4.22.15) inhibitor00low000000
yh 439
0
aromatic amide;
isopropyl ester;
secondary carboxamide		00low000000
cyc 682
0
nitrile;
nucleoside analogue;
secondary carboxamide		antimetabolite;
antineoplastic agent;
DNA synthesis inhibitor;
prodrug		00low000000
sceptrin
0
pyrroles;
secondary carboxamide		00low000000
n(beta)-alanyldopamine
0
catechols;
primary amino compound;
secondary carboxamide		00low000000
monoacetylcadaverine
0
acetamides;
N-substituted cadaverine;
primary amino compound;
secondary carboxamide		human metabolite00low000000
N-(1-phenylethyl)acetamide
0
acetamides;
secondary carboxamide		00low000000
2,2,2-trifluoro-N-[2-(1H-indol-3-yl)ethyl]acetamide
0
indoles;
secondary carboxamide;
trifluoroacetamide		00low000000
vibriobactin
0
1,3-oxazoles;
secondary carboxamide		siderophore00low000000
bms 195614
0
benzoic acids;
quinolines;
secondary carboxamide		retinoic acid receptor alpha antagonist00low000000
tempace
0
aminoxyls;
piperidinecarboxamide;
secondary carboxamide		radiation protective agent;
radical scavenger		00low000000
dimethyloxalylglycine
0
glycine derivative;
methyl ester;
secondary carboxamide		EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor;
neuroprotective agent		00low000000
s 1033
0
(trifluoromethyl)benzenes;
imidazoles;
pyridines;
pyrimidines;
secondary amino compound;
secondary carboxamide		anticoronaviral agent;
antineoplastic agent;
tyrosine kinase inhibitor		00low000000
3-methyl-2-[[oxo-(4-pentoxyphenyl)methyl]amino]butanoic acid
0
secondary carboxamide00low000000
cinromide
0
cinnamamides;
secondary carboxamide		00low000000
4-[[2-furanyl(oxo)methyl]amino]benzoic acid propan-2-yl ester
0
aromatic amide;
furans;
isopropyl ester;
secondary carboxamide		00low000000
2,2,2-trifluoro-N-(2-methyl-8-quinolinyl)acetamide
0
quinolines;
secondary carboxamide;
trifluoroacetamide		00low000000
N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-pyrazinecarboxamide
0
primary carboxamide;
pyrazines;
secondary carboxamide		00low000000
2-[[oxo(thiophen-2-yl)methyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid propan-2-yl ester
0
aromatic amide;
isopropyl ester;
secondary carboxamide;
thiophenes		00low000000
N-[1-[(4-chlorophenyl)methyl]-4-pyrazolyl]-2-pyrazinecarboxamide
0
pyrazines;
secondary carboxamide		00low000000
4-[[(4-bromo-2-ethyl-3-pyrazolyl)-oxomethyl]amino]benzoic acid propan-2-yl ester
0
aromatic amide;
isopropyl ester;
secondary carboxamide		00low000000
(2S)-2-[[(2-chlorophenyl)-oxomethyl]amino]-3-methylbutanoic acid (6-nitro-4H-1,3-benzodioxin-8-yl)methyl ester
0
secondary carboxamide00low000000
N-[(2S)-1-(1H-benzimidazol-2-ylamino)-3-methyl-1-oxobutan-2-yl]-3,5-dimethoxybenzamide
0
secondary carboxamide00low000000
2-(2,4-dioxo-1H-pyrimidin-6-yl)-N-[2-(4-morpholinyl)ethyl]acetamide
0
morpholines;
pyrimidone;
secondary carboxamide;
tertiary amino compound		00low000000
N-[(4-chlorophenyl)methyl]-2-(2,4-dioxo-1H-pyrimidin-6-yl)acetamide
0
monochlorobenzenes;
pyrimidone;
secondary carboxamide		00low000000
N-[(2S)-1-(1H-benzimidazol-2-ylamino)-3-methyl-1-oxobutan-2-yl]-3-methylbenzamide
0
secondary carboxamide00low000000
2,2,2-trifluoro-N-(5-oxo-1-phenyl-4H-pyrazol-3-yl)acetamide
0
pyrazoles;
secondary carboxamide;
trifluoroacetamide		00low000000
N-(2-anilino-2-oxoethyl)-2-methoxybenzamide
0
secondary carboxamide00low000000
N-[5-[(2,6-dichlorophenyl)methylthio]-1,3,4-thiadiazol-2-yl]-5-methyl-2-pyrazinecarboxamide
0
pyrazines;
secondary carboxamide		00low000000
(2S)-3-methyl-2-[[(3-methylphenyl)-oxomethyl]amino]butanoic acid (4-oxo-2-pyrimido[2,1-b][1,3]benzothiazolyl)methyl ester
0
secondary carboxamide00low000000
n-(1-oxyl-2,2,6,6-tetramethyl-4-piperidinyl)iodoacetamide
0
aminoxyls;
organoiodine compound;
piperidinecarboxamide;
secondary carboxamide		radical scavenger;
spin label		00low000000
ANA-12
0
1-benzothiophenes;
caprolactams;
secondary carboxamide		antidepressant;
anxiolytic drug;
tropomyosin-related kinase B receptor antagonist		00low000000
N-([biphenyl]-2-yl)-3-cyclopentylpropanamide
0
biphenyls;
cyclopentanes;
secondary carboxamide		00low000000
sr 144528
0
bridged compound;
monochlorobenzenes;
pyrazoles;
secondary carboxamide		CB2 receptor antagonist;
EC 2.3.1.26 (sterol O-acyltransferase) inhibitor		00low000000
N-(1,3-benzodioxol-5-ylmethyl)-N-[2-(cyclohexylamino)-2-oxo-1-pyridin-4-ylethyl]-2,2,2-trifluoroacetamide
0
benzodioxoles;
pyridines;
secondary carboxamide;
tertiary carboxamide;
trifluoroacetamide		00low000000
N-[2-(cyclohexylamino)-2-oxo-1-thiophen-2-ylethyl]-2,2,2-trifluoro-N-(4-methylphenyl)acetamide
0
secondary carboxamide;
tertiary carboxamide;
thiophenes;
trifluoroacetamide		00low000000
ML162
0
monochlorobenzenes;
monomethoxybenzene;
organochlorine compound;
secondary carboxamide;
tertiary carboxamide;
thiophenes		EC 1.11.1.9 (glutathione peroxidase) inhibitor;
ferroptosis inducer		00low000000
N-[3-(N-(2-chloro-1-oxoethyl)-4-nitroanilino)propyl]-2,2,2-trifluoroacetamide
0
C-nitro compound;
secondary carboxamide;
tertiary carboxamide;
trifluoroacetamide		00low000000
2-[[2-(3,4-dimethoxyanilino)-2-oxoethyl]thio]-3-pyridinecarboxylic acid propan-2-yl ester
0
dimethoxybenzene;
isopropyl ester;
secondary carboxamide		00low000000
fagaramide
0
cinnamamides;
secondary carboxamide		00low000000
arachidonyl dopamine
0
catechols;
fatty amide;
N-(fatty acyl)-dopamine;
secondary carboxamide		00low000000
n-oleoyldopamine
0
catechols;
fatty amide;
N-(fatty acyl)-dopamine;
secondary carboxamide		TRPV1 agonist00low000000
tranilast
0
amidobenzoic acid;
cinnamamides;
dimethoxybenzene;
secondary carboxamide		anti-allergic agent;
anti-asthmatic drug;
antineoplastic agent;
aryl hydrocarbon receptor agonist;
calcium channel blocker;
hepatoprotective agent;
nephroprotective agent		00low000000
arachidonyl-2-chloroethylamide
0
fatty amide;
organochlorine compound;
secondary carboxamide;
synthetic cannabinoid		CB1 receptor agonist;
CB2 receptor agonist;
neuroprotective agent		00low000000
l796778
0
benzenes;
C-nitro compound;
L-lysine derivative;
L-phenylalanine derivative;
methyl ester;
oligopeptide;
secondary carboxamide;
ureas		somatostatin receptor agonist00low000000
l803087
0
benzenes;
fluoroindole;
guanidines;
L-arginine derivative;
methyl ester;
phenylindole;
secondary carboxamide		somatostatin receptor agonist00low000000
n-cinnamoyltyramine
0
cinnamamides;
phenols;
secondary carboxamide		allelochemical;
antimicrobial agent;
phytoalexin;
platelet aggregation inhibitor		00low000000
4-amylcinnamoylanthranilic acid
0
amidobenzoic acid;
cinnamamides;
secondary carboxamide		EC 3.1.1.4 (phospholipase A2) inhibitor;
TRP channel blocker		00low000000
batimastat
0
hydroxamic acid;
L-phenylalanine derivative;
organic sulfide;
secondary carboxamide;
thiophenes;
triamide		angiogenesis inhibitor;
antineoplastic agent;
matrix metalloproteinase inhibitor		00low000000
pederin
0
cyclic ketal;
diol;
oxanes;
polyketide;
secondary alcohol;
secondary carboxamide		antimitotic;
antineoplastic agent;
bacterial metabolite;
vesicant		00low000000
cinanserin
0
aryl sulfide;
cinnamamides;
secondary carboxamide;
tertiary amino compound		anticoronaviral agent;
antiviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor		00low000000
pepstatin
0
pentapeptide;
secondary carboxamide		bacterial metabolite;
EC 3.4.23.* (aspartic endopeptidase) inhibitor		00low000000
ximelagatran
0
amidoxime;
azetidines;
carboxamide;
ethyl ester;
hydroxylamines;
secondary amino compound;
secondary carboxamide;
tertiary carboxamide		anticoagulant;
EC 3.4.21.5 (thrombin) inhibitor;
prodrug;
serine protease inhibitor		00low000000
(6R,7R)-7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)-1-oxoethyl]amino]-7-methoxy-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
0
dicarboxylic acid;
secondary carboxamide		00low000000
salubrinal
0
aminal;
organochlorine compound;
quinolines;
secondary carboxamide;
thioureas		00low000000
DPI2
0
benzenes;
morpholines;
secondary carboxamide;
tertiary amino compound;
thiazolidinone		ferroptosis inducer00low000000
n-feruloylserotonin
0
aromatic ether;
cinnamamides;
hydroxyindoles;
phenols;
secondary carboxamide		plant metabolite00low000000
oroidin
0
pyrroles;
secondary carboxamide		metabolite00low000000
ro 42-5892
0
cyclopropanes;
diol;
L-histidine derivative;
secondary carboxamide;
sulfone		antihypertensive agent;
EC 3.4.23.15 (renin) inhibitor;
peptidomimetic;
vasodilator agent		00low000000
l 744832
0
benzenes;
ether;
isopropyl ester;
secondary carboxamide;
sulfone;
thiol		antineoplastic agent;
EC 2.5.1.58 (protein farnesyltransferase) inhibitor;
geroprotector		00low000000
mocetinostat
0
aminopyrimidine;
benzamides;
pyridines;
secondary amino compound;
secondary carboxamide;
substituted aniline		antineoplastic agent;
apoptosis inducer;
autophagy inducer;
cardioprotective agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
hepatotoxic agent		00low000000
l 779976
0
benzimidazoles;
indoles;
piperidinecarboxamide;
primary amino compound;
secondary carboxamide		neuroprotective agent;
somatostatin receptor agonist		00low000000
ustiloxin b
0
aromatic ether;
heterodetic cyclic peptide;
macrocycle;
phenols;
secondary alcohol;
secondary carboxamide;
sulfoxide		Aspergillus metabolite;
microtubule-destabilising agent;
mycotoxin		00low000000
avenanthramide b
0
amidobenzoic acid;
cinnamamides;
monohydroxybenzoic acid;
monomethoxybenzene;
phenols;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
phytoalexin		00low000000
azd2858
0
aromatic amine;
N-methylpiperazine;
pyrazines;
pyridines;
secondary carboxamide;
sulfonamide		antineoplastic agent;
bone density conservation agent;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
Wnt signalling activator		00low000000
betrixaban
0
benzamides;
guanidines;
monochloropyridine;
monomethoxybenzene;
secondary carboxamide		anticoagulant;
EC 3.4.21.6 (coagulation factor Xa) inhibitor		00low000000
fr 900848
0
cyclopropanes;
nucleoside analogue;
olefinic compound;
polyketide;
secondary carboxamide		antifungal agent;
bacterial metabolite		00low000000
n-benzylhexadecanamide
0
macamide;
secondary carboxamide		EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor;
neuroprotective agent;
plant metabolite		00low000000
chlorantranilipole
0
monochlorobenzenes;
organobromine compound;
pyrazole insecticide;
pyrazoles;
pyridines;
secondary carboxamide		ryanodine receptor agonist00low000000
cenicriviroc
0
aromatic ether;
benzazocine;
diether;
imidazoles;
secondary carboxamide;
sulfoxide		anti-HIV agent;
anti-inflammatory agent;
antirheumatic drug;
chemokine receptor 2 antagonist;
chemokine receptor 5 antagonist		00low000000
at 7519
0
dichlorobenzene;
piperidines;
pyrazoles;
secondary carboxamide		antineoplastic agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor		00low000000
azd 1152
0
anilide;
monoalkyl phosphate;
monofluorobenzenes;
pyrazoles;
quinazolines;
secondary amino compound;
secondary carboxamide;
tertiary amino compound		antineoplastic agent;
Aurora kinase inhibitor;
prodrug		00low000000
MI-63
0
azaspiro compound;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
oxindoles;
pyrrolidines;
secondary carboxamide		apoptosis inducer00low000000
PF-00835231
0
aromatic ether;
indolecarboxamide;
L-leucine derivative;
primary alcohol;
pyrrolidin-2-ones;
secondary carboxamide		anticoronaviral agent;
drug metabolite;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor		00low000000
cyantraniliprole
0
nitrile;
organobromine compound;
organochlorine compound;
pyrazole insecticide;
pyridines;
secondary carboxamide		ryanodine receptor agonist00low000000
VPC 23019
0
aromatic amide;
D-serine derivative;
organic phosphate;
phosphoric ester;
secondary carboxamide		sphingosine-1-phosphate receptor 1 antagonist;
sphingosine-1-phosphate receptor 3 antagonist		00low000000
pd 0348292
0
monochlorobenzenes;
monofluorobenzenes;
pyridone;
pyrrolidines;
secondary carboxamide;
ureas		anticoagulant;
EC 3.4.21.6 (coagulation factor Xa) inhibitor;
serine protease inhibitor		00low000000
narlaprevir
0
azabicyclohexane;
cyclopropanes;
pyrrolidinecarboxamide;
secondary carboxamide;
sulfone;
tertiary carboxamide;
ureas		anticoronaviral agent;
antiviral drug;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
hepatitis C protease inhibitor		00low000000
tosedostat
0
carboxylic ester;
hydroxamic acid;
secondary carboxamide		00low000000
4-chloro-N-[1-[[5-(ethylthio)-1,3,4-thiadiazol-2-yl]amino]-3-methyl-1-oxobutan-2-yl]benzamide
0
secondary carboxamide00low000000
azd 1152-hqpa
0
anilide;
monofluorobenzenes;
primary alcohol;
pyrazoles;
quinazolines;
secondary amino compound;
secondary carboxamide;
tertiary amino compound		antineoplastic agent;
Aurora kinase inhibitor		00low000000
CDN1163
0
aromatic ether;
quinolines;
secondary carboxamide		SERCA activator00low000000
(2S)-2-[[[5-[[5-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]pentylamino]-oxomethyl]-1H-imidazol-4-yl]-oxomethyl]amino]propanoic acid tert-butyl ester
0
secondary carboxamide;
tert-butyl ester		00low000000
(2S)-2-[[[5-[[methyl-(phenylmethyl)amino]-oxomethyl]-1H-imidazol-4-yl]-oxomethyl]amino]-6-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]hexanoic acid tert-butyl ester
0
secondary carboxamide;
tert-butyl ester;
tertiary carboxamide		00low000000
(2S,3S,4R)-4-cyclopropyl-2-ethoxy-3-(3-hydroxypropyl)-N-prop-2-ynyl-3,4-dihydro-2H-pyran-6-carboxamide
0
secondary carboxamide00low000000
sid 26681509
0
carbohydrazide;
L-tryptophan derivative;
secondary carboxamide;
tert-butyl ester;
thioester		antiplasmodial drug;
cathepsin L (EC 3.4.22.15) inhibitor		00low000000
azd 7545
0
benzamides;
monochlorobenzenes;
organofluorine compound;
secondary carboxamide;
sulfone;
tertiary alcohol;
tertiary carboxamide		EC 2.7.11.2 - [pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitor;
hypoglycemic agent		00low000000
sm 164
0
benzenes;
organic heterobicyclic compound;
secondary carboxamide;
triazoles		antineoplastic agent;
apoptosis inducer;
radiosensitizing agent		00low000000
sch772984
0
biaryl;
indazoles;
N-acylpiperazine;
N-alkylpyrrolidine;
N-arylpiperazine;
pyridines;
pyrimidines;
pyrrolidinecarboxamide;
secondary carboxamide;
tertiary amino compound;
tertiary carboxamide		analgesic;
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor		00low000000
GRL-0617
0
benzamides;
naphthalenes;
secondary carboxamide;
substituted aniline		anticoronaviral agent;
protease inhibitor		00low000000
entrectinib
0
benzamides;
difluorobenzene;
indazoles;
N-methylpiperazine;
oxanes;
secondary amino compound;
secondary carboxamide		antibacterial agent;
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor		00low000000
TAK-580
0
1,3-thiazolecarboxamide;
aminopyrimidine;
chloropyridine;
organofluorine compound;
pyrimidinecarboxamide;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
B-Raf inhibitor		00low000000
cx 5461
0
diazepine;
naphthyridine derivative;
organic heterotetracyclic compound;
pyrazines;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
EC 2.7.7.6 (RNA polymerase) inhibitor		00low000000
KOM70144
0
acetamides;
benzamides;
naphthalenes;
secondary carboxamide		anticoronaviral agent;
protease inhibitor		00low000000
monepantel
0
(trifluoromethyl)benzenes;
aromatic ether;
aryl sulfide;
nitrile;
secondary carboxamide		anthelminthic drug;
nematicide		00low000000
ulixacaltamide
0
benzamides;
monochlorobenzenes;
monofluorobenzenes;
piperidines;
secondary carboxamide		non-narcotic analgesic;
T-type calcium channel blocker		00low000000
EG00229
0
benzothiadiazole;
dicarboxylic acid monoamide;
L-arginine derivative;
secondary carboxamide;
sulfonamide;
thiophenes		angiogenesis inhibitor;
antineoplastic agent;
neuropilin receptor antagonist		00low000000
tak-632
0
(trifluoromethyl)benzenes;
aromatic ether;
benzothiazoles;
cyclopropylcarboxamide;
monofluorobenzenes;
nitrile;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
B-Raf inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
necroptosis inhibitor		00low000000
lgk974
0
bipyridines;
pyrazines;
pyridines;
secondary carboxamide		Wnt signalling inhibitor00low000000
gsk-5498a
0
(trifluoromethyl)benzenes;
difluorobenzene;
pyrazoles;
secondary carboxamide		calcium channel blocker00low000000
2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide
0
aromatic ether;
methylpyridines;
olefinic compound;
quinazolines;
secondary amino compound;
secondary carboxamide;
toluenes		00low000000
raltegravir
0
1,2,4-oxadiazole;
dicarboxylic acid amide;
hydroxypyrimidine;
monofluorobenzenes;
pyrimidone;
secondary carboxamide		antiviral drug;
HIV-1 integrase inhibitor		00low000000
gsk1265744
0
difluorobenzene;
monocarboxylic acid amide;
organic heterotricyclic compound;
secondary carboxamide		HIV-1 integrase inhibitor00low000000
dolutegravir
0
difluorobenzene;
monocarboxylic acid amide;
organic heterotricyclic compound;
secondary carboxamide		HIV-1 integrase inhibitor00low000000
MK-8353
0
aromatic ether;
dihydropyridine;
indazoles;
methyl sulfide;
N-alkylpyrrolidine;
pyridines;
pyrrolidinecarboxamide;
secondary carboxamide;
tertiary carboxamide;
triazoles		antineoplastic agent;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor		00low000000
acp-196
0
aromatic amine;
benzamides;
imidazopyrazine;
pyridines;
pyrrolidinecarboxamide;
secondary carboxamide;
tertiary carboxamide;
ynone		antineoplastic agent;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor		00low000000
gsk343
0
aminopyridine;
indazoles;
N-alkylpiperazine;
N-arylpiperazine;
pyridone;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
EC 2.1.1.43 (enhancer of zeste homolog 2) inhibitor		00low000000
osimertinib
0
acrylamides;
aminopyrimidine;
biaryl;
indoles;
monomethoxybenzene;
secondary amino compound;
secondary carboxamide;
substituted aniline;
tertiary amino compound		antineoplastic agent;
epidermal growth factor receptor antagonist		00low000000
ivosidenib
0
cyanopyridine;
monochlorobenzenes;
organofluorine compound;
pyrrolidin-2-ones;
secondary carboxamide;
tertiary carboxamide		antineoplastic agent;
EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor		00low000000
atogepant
0
azaspiro compound;
organic heterotetracyclic compound;
piperidones;
secondary carboxamide;
trifluorobenzene		calcitonin gene-related peptide receptor antagonist00low000000
DDR1-IN-1
0
(trifluoromethyl)benzenes;
aromatic ether;
benzamides;
N-alkylpiperazine;
oxindoles;
secondary carboxamide		EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor00low000000
bictegravir
0
monocarboxylic acid amide;
organic heterotetracyclic compound;
secondary carboxamide;
trifluorobenzene		HIV-1 integrase inhibitor00low000000
AZ3451
0
benzimidazoles;
benzodioxoles;
nitrile;
organobromine compound;
secondary carboxamide		anti-inflammatory agent;
autophagy inducer;
PAR2 negative allosteric modulator		00low000000
MMP-9-IN-1
0
aromatic compound;
organic sulfide;
organofluorine compound;
pyrimidone;
secondary carboxamide		antineoplastic agent;
EC 3.4.24.35 (gelatinase B) inhibitor		00low000000
N-[(2S)-3-cyclohexyl-1-oxo-1-({(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)propan-2-yl]-1H-indole-2-carboxamide
0
aldehyde;
indolecarboxamide;
oligopeptide;
pyrrolidin-2-ones;
secondary carboxamide		anticoronaviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor		00low000000
3-fluoro-Nalpha-(1H-indol-2-ylcarbonyl)-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide
0
aldehyde;
indolecarboxamide;
monofluorobenzenes;
oligopeptide;
pyrrolidin-2-ones;
secondary carboxamide		anticoronaviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor		00low000000
PF-07304814
0
aromatic ether;
indolecarboxamide;
L-leucine derivative;
phosphate monoester;
pyrrolidin-2-ones;
secondary carboxamide		anticoronaviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
prodrug		00low000000
nirmatrelvir
0
azabicyclohexane;
nitrile;
organofluorine compound;
pyrrolidin-2-ones;
pyrrolidinecarboxamide;
secondary carboxamide;
tertiary carboxamide		anticoronaviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor		00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
nitrofurazone
0
nitrofuran antibiotic;
semicarbazone		antibacterial drug00low000000
benzyl isothiocyanate
0
benzenes;
isothiocyanate		antibacterial drug00low000000
cinoxacin
0
cinnolines;
oxacycle;
oxo carboxylic acid		antibacterial drug;
antiinfective agent		00low000000
ciprofloxacin
0
aminoquinoline;
cyclopropanes;
fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone;
zwitterion		antibacterial drug;
antiinfective agent;
antimicrobial agent;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
environmental contaminant;
topoisomerase IV inhibitor;
xenobiotic		00low000000
enoxacin
0
1,8-naphthyridine derivative;
amino acid;
fluoroquinolone antibiotic;
monocarboxylic acid;
N-arylpiperazine;
quinolone antibiotic		antibacterial drug;
DNA synthesis inhibitor		00low000000
fleroxacin
0
difluorobenzene;
fluoroquinolone antibiotic;
monocarboxylic acid;
N-alkylpiperazine;
quinolines		antibacterial drug;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
topoisomerase IV inhibitor		00low000000
furazolidone
0
nitrofuran antibiotic;
oxazolidines		antibacterial drug;
antiinfective agent;
antitrichomonal drug;
EC 1.4.3.4 (monoamine oxidase) inhibitor		00low000000
methenamine
0
polyazaalkane;
polycyclic cage;
tetramine		antibacterial drug00low000000
metronidazole
0
C-nitro compound;
imidazoles;
primary alcohol		antiamoebic agent;
antibacterial drug;
antimicrobial agent;
antiparasitic agent;
antitrichomonal drug;
environmental contaminant;
prodrug;
radiosensitizing agent;
xenobiotic		00low000000
nadifloxacin
0
heteroarylpiperidine;
hydroxypiperidine;
pyridoquinoline;
quinolone antibiotic		antibacterial drug00low000000
nalidixic acid
0
1,8-naphthyridine derivative;
monocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antimicrobial agent;
DNA synthesis inhibitor		00low000000
norfloxacin
0
fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone		antibacterial drug;
DNA synthesis inhibitor;
environmental contaminant;
xenobiotic		00low000000
oxolinic acid
0
aromatic carboxylic acid;
organic heterotricyclic compound;
oxacycle;
quinolinemonocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antifungal agent;
antiinfective agent;
antimicrobial agent;
enzyme inhibitor		00low000000
pipemidic acid
0
amino acid;
monocarboxylic acid;
N-arylpiperazine;
pyridopyrimidine;
quinolone antibiotic		antibacterial drug;
DNA synthesis inhibitor		00low000000
piromidic acid
0
monocarboxylic acid;
pyridopyrimidine;
pyrrolidines;
quinolone antibiotic;
tertiary amino compound		antibacterial drug;
DNA synthesis inhibitor		00low000000
roxarsone
0
2-nitrophenols;
organoarsonic acid		agrochemical;
animal growth promotant;
antibacterial drug;
coccidiostat		00low000000
sulfabenzamide
0
benzenes;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
antimicrobial drug		00low000000
sulfacetamide
0
N-sulfonylcarboxamide;
substituted aniline		antibacterial drug;
antiinfective agent;
antimicrobial agent;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor		00low000000
sulfamethazine
0
pyrimidines;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
antiinfective agent;
antimicrobial agent;
carcinogenic agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
ligand;
xenobiotic		00low000000
sulfaphenazole
0
primary amino compound;
pyrazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 1.14.13.67 (quinine 3-monooxygenase) inhibitor;
P450 inhibitor		00low000000
sulfisoxazole
0
isoxazoles;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
drug allergen		00low000000
thiram
0
organic disulfideantibacterial drug;
antifungal agrochemical;
antiseptic drug		00low000000
tinidazole
0
imidazolesantiamoebic agent;
antibacterial drug;
antiparasitic agent;
antiprotozoal drug		00low000000
trimethoprim
0
aminopyrimidine;
methoxybenzenes		antibacterial drug;
diuretic;
drug allergen;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
environmental contaminant;
xenobiotic		00low000000
cephaloridine
0
beta-lactam antibiotic allergen;
cephalosporin;
semisynthetic derivative		antibacterial drug00low000000
penicillin g
0
penicillin allergen;
penicillin		antibacterial drug;
drug allergen;
epitope		00low000000
chloramphenicol
0
C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor		00low000000
cephalothin
0
azabicycloalkene;
beta-lactam antibiotic allergen;
carboxylic acid;
cephalosporin;
semisynthetic derivative;
thiophenes		antibacterial drug;
antimicrobial agent		00low000000
methicillin
0
penicillin allergen;
penicillin		antibacterial drug00low000000
cloxacillin
0
penicillin allergen;
penicillin;
semisynthetic derivative		antibacterial agent;
antibacterial drug		00low000000
oxacillin
0
penicillinantibacterial agent;
antibacterial drug		00low000000
ampicillin
0
beta-lactam antibiotic;
penicillin allergen;
penicillin		antibacterial drug00low000000
chlorquinaldol
0
monohydroxyquinoline;
organochlorine compound		antibacterial drug;
antiprotozoal drug;
antiseptic drug		00low000000
sulfachlorpyridazine
0
organochlorine compound;
pyridazines;
sulfonamide		antibacterial drug;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor		00low000000
chlorphenesin
0
glycol;
monochlorobenzenes;
propane-1,2-diols		antibacterial drug;
antifungal drug;
muscle relaxant		00low000000
framycetin
0
aminoglycosideallergen;
antibacterial drug;
Escherichia coli metabolite		00low000000
nafcillin
0
penicillin allergen;
penicillin		antibacterial drug00low000000
vancomycin
0
glycopeptideantibacterial drug;
antimicrobial agent;
bacterial metabolite		00low000000
spectinomycin
0
cyclic acetal;
cyclic hemiketal;
cyclic ketone;
pyranobenzodioxin;
secondary alcohol;
secondary amino compound		antibacterial drug;
antimicrobial agent;
bacterial metabolite		00low000000
sulfadoxine
0
pyrimidines;
sulfonamide		antibacterial drug;
antimalarial		00low000000
dicloxacillin
0
dichlorobenzene;
penicillin		antibacterial drug00low000000
cyclacillin
0
penicillinantibacterial drug00low000000
streptomycin
0
antibiotic antifungal drug;
antibiotic fungicide;
streptomycins		antibacterial drug;
antifungal agrochemical;
antimicrobial agent;
antimicrobial drug;
bacterial metabolite;
protein synthesis inhibitor		00low000000
carbenicillin
0
penicillin allergen;
penicillin		antibacterial drug00low000000
floxacillin
0
penicillin allergen;
penicillin		antibacterial drug00low000000
cephalexin
0
beta-lactam antibiotic allergen;
cephalosporin;
semisynthetic derivative		antibacterial drug00low000000
ornidazole
0
C-nitro compound;
imidazoles;
organochlorine compound;
secondary alcohol		antiamoebic agent;
antibacterial drug;
antiinfective agent;
antiprotozoal drug;
antitrichomonal drug;
epitope		00low000000
cephapirin
0
cephalosporinantibacterial drug00low000000
ribostamycin
0
amino cyclitol glycoside;
aminoglycoside antibiotic		antibacterial drug;
antimicrobial agent;
metabolite		00low000000
cefazolin
0
beta-lactam antibiotic allergen;
cephalosporin;
tetrazoles;
thiadiazoles		antibacterial drug00low000000
amoxicillin
0
penicillin allergen;
penicillin		antibacterial drug00low000000
amdinocillin
0
penicillinantibacterial drug;
antiinfective agent		00low000000
ticarcillin
0
penicillin allergen;
penicillin		antibacterial drug00low000000
amikacin
0
alpha-D-glucoside;
amino cyclitol glycoside;
aminoglycoside;
carboxamide		antibacterial drug;
antimicrobial agent;
nephrotoxin		00low000000
cephradine
0
beta-lactam antibiotic allergen;
cephalosporin		antibacterial drug00low000000
cefmetazole
0
cephalosporinantibacterial drug00low000000
ceforanide
0
cephalosporinantibacterial drug00low000000
cefonicid
0
cephalosporinantibacterial drug00low000000
piperacillin
0
penicillin allergen;
penicillin		antibacterial drug00low000000
cefotiam
0
beta-lactam antibiotic allergen;
cephalosporin;
semisynthetic derivative		antibacterial drug00low000000
cefoperazone
0
cephalosporinantibacterial drug00low000000
moxalactam
0
cephalosporin;
oxacephem		antibacterial drug00low000000
cefadroxil anhydrous
0
cephalosporinantibacterial drug00low000000
cefaclor anhydrous
0
cephalosporinantibacterial drug;
drug allergen		00low000000
pefloxacin
0
fluoroquinolone antibiotic;
monocarboxylic acid;
N-alkylpiperazine;
N-arylpiperazine;
quinolone antibiotic;
quinolone		antibacterial drug;
antiinfective agent;
DNA synthesis inhibitor		00low000000
difloxacin
0
fluoroquinolone antibiotic;
monocarboxylic acid;
monofluorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
quinolone antibiotic;
quinolone		antibacterial drug;
Mycoplasma genitalium metabolite		00low000000
cefprozil
0
cephalosporin;
semisynthetic derivative		antibacterial drug00low000000
ciprofloxacin hydrochloride anhydrous
0
hydrochlorideantibacterial drug;
antiinfective agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
topoisomerase IV inhibitor		00low000000
spectinomycin dihydrochloride
0
hydrochlorideantibacterial drug;
antimicrobial agent		00low000000
flomoxef
0
N-acyl-amino acid;
organonitrogen heterocyclic antibiotic;
oxacephem		antibacterial drug00low000000
salicylhydroxamic acid
0
hydroxamic acid;
phenols		antibacterial drug;
EC 1.11.2.2 (myeloperoxidase) inhibitor;
EC 3.5.1.5 (urease) inhibitor;
trypanocidal drug		00low000000
arbekacin
0
aminoglycoside;
kanamycins		antibacterial agent;
antibacterial drug;
antimicrobial agent;
protein synthesis inhibitor		00low000000
brodimoprim
0
aminopyrimidine;
bromobenzenes;
methoxybenzenes		antibacterial drug;
antiinfective agent;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor		00low000000
sulfaperine
0
pyrimidines;
substituted aniline;
sulfonamide antibiotic		antibacterial drug00low000000
cefaloram
0
cephalosporinantibacterial drug00low000000
flurithromycin
0
cyclic ketone;
erythromycin derivative;
organofluorine compound;
semisynthetic derivative		antibacterial drug00low000000
ljc 10627
0
carbapenems;
organic sulfide;
pyrazolotriazole		antibacterial drug00low000000
cefazedone
0
4-pyridones;
carboxylic acid;
cephalosporin;
semisynthetic derivative;
thiadiazoles		antibacterial drug00low000000
benzoylmetronidazole
0
benzoate esterantibacterial drug;
antimicrobial agent;
antiparasitic agent;
antitrichomonal drug;
prodrug		00low000000
clarithromycin
0
macrolide antibioticantibacterial drug;
environmental contaminant;
protein synthesis inhibitor;
xenobiotic		00low000000
quinacillin
0
penicillin;
quinoxaline derivative		antibacterial drug00low000000
moxifloxacin hydrochloride
0
hydrochlorideantibacterial drug00low000000
imipenem, anhydrous
0
beta-lactam antibiotic allergen;
carbapenems;
zwitterion		antibacterial drug00low000000
amdinocillin pivoxil
0
penicillanic acid ester;
penicillin;
pivaloyloxymethyl ester		antibacterial drug;
antiinfective agent;
prodrug		00low000000
pefloxacin mesylate
0
methanesulfonate saltantibacterial drug00low000000
garenoxacin
0
aromatic ether;
cyclopropanes;
isoindoles;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone antibiotic		antibacterial drug;
non-steroidal anti-inflammatory drug		00low000000
levofloxacin
0
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid;
fluoroquinolone antibiotic;
quinolone antibiotic		antibacterial drug;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
topoisomerase IV inhibitor		00low000000
ertapenem
0
carbapenemcarboxylic acid;
pyrrolidinecarboxamide		antibacterial drug00low000000
moxifloxacin
0
aromatic ether;
cyclopropanes;
fluoroquinolone antibiotic;
pyrrolidinopiperidine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone		antibacterial drug00low000000
a 195773
0
macrolide antibiotic;
monosaccharide derivative;
quinolines		antibacterial drug;
protein synthesis inhibitor		00low000000
paromomycin
0
amino cyclitol glycoside;
aminoglycoside antibiotic		anthelminthic drug;
antibacterial drug;
antiparasitic agent;
antiprotozoal drug		00low000000
rosoxacin
0
pyridines;
quinolinemonocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antiinfective agent		00low000000
meropenem
0
alpha,beta-unsaturated monocarboxylic acid;
carbapenemcarboxylic acid;
organic sulfide;
pyrrolidinecarboxamide		antibacterial agent;
antibacterial drug;
drug allergen		00low000000
cefoxitin
0
beta-lactam antibiotic allergen;
cephalosporin;
cephamycin;
semisynthetic derivative		antibacterial drug00low000000
silver sulfadiazine
0
pyrimidines;
silver salt;
sulfonamidate		antibacterial drug;
antimicrobial agent		00low000000
kanamycin sulfate
0
aminoglycoside sulfate saltantibacterial drug;
geroprotector		00low000000
linezolid
0
acetamides;
morpholines;
organofluorine compound;
oxazolidinone		antibacterial drug;
protein synthesis inhibitor		00low000000
alpha bitter acid
0
aromatic ketone;
cyclic ketone;
diketone;
tertiary alpha-hydroxy ketone;
triol		antibacterial drug;
antioxidant;
cyclooxygenase 2 inhibitor;
metabolite		00low000000
hetacillin
0
penicillinantibacterial drug00low000000
roxithromycin
0
erythromycin derivative;
macrolide;
semisynthetic derivative		antibacterial drug00low000000
mupirocin
0
alpha,beta-unsaturated carboxylic ester;
epoxide;
monocarboxylic acid;
oxanes;
secondary alcohol;
triol		antibacterial drug;
bacterial metabolite;
protein synthesis inhibitor		00low000000
zithromax
0
macrolide antibioticantibacterial drug;
environmental contaminant;
xenobiotic		00low000000
cefamandole
0
cephalosporin;
semisynthetic derivative		antibacterial drug00low000000
cefpiramide
0
carboxylic acid;
cephalosporin		antibacterial drug00low000000
mezlocillin
0
penicillin allergen;
penicillin		antibacterial drug00low000000
cefsulodin
0
cephalosporin;
organosulfonic acid;
primary carboxamide		antibacterial drug00low000000
tiamulin
0
carbotricyclic compound;
carboxylic ester;
cyclic ketone;
organic sulfide;
secondary alcohol;
semisynthetic derivative;
tertiary amino compound;
tetracyclic diterpenoid		antibacterial drug00low000000
sulfathiourea
0
substituted aniline;
sulfonamide antibiotic;
thioureas		antibacterial drug;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor		00low000000
telavancin
0
glycopeptideantibacterial drug;
antimicrobial agent		00low000000
apramycin
0
2-deoxystreptamine derivative;
aminoglycoside;
organic heterobicyclic compound		antibacterial drug;
antimicrobial agent		00low000000
clavulanic acid
0
oxapenamantibacterial drug;
anxiolytic drug;
bacterial metabolite;
EC 3.5.2.6 (beta-lactamase) inhibitor		00low000000
josamycin
0
acetate ester;
aldehyde;
disaccharide derivative;
glycoside;
macrolide antibiotic;
tertiary alcohol;
tertiary amino compound		antibacterial drug;
metabolite		00low000000
acetylspiramycin
0
acetate ester;
aldehyde;
disaccharide derivative;
ether;
macrolide;
tertiary amino compound		antibacterial drug;
antimicrobial agent;
bacterial metabolite		00low000000
7432 s
0
cephalosporin;
dicarboxylic acid		antibacterial drug00low000000
tilmicosin
0
enone;
macrolide antibiotic;
monosaccharide derivative		antibacterial drug;
calcium channel blocker;
cardiotoxic agent		00low000000
ly 163892
0
carbacephem;
zwitterion		antibacterial drug;
antimicrobial agent		00low000000
sirolimus
0
antibiotic antifungal drug;
cyclic acetal;
cyclic ketone;
ether;
macrolide lactam;
organic heterotricyclic compound;
secondary alcohol		antibacterial drug;
anticoronaviral agent;
antineoplastic agent;
bacterial metabolite;
geroprotector;
immunosuppressive agent;
mTOR inhibitor		00low000000
cefodizime
0
1,3-thiazoles;
cephalosporin;
oxime O-ether		antibacterial drug;
EC 1.14.18.1 (tyrosinase) inhibitor		00low000000
cefixime
0
cephalosporinantibacterial drug;
drug allergen		00low000000
virginiamycin factor s1
0
cyclodepsipeptide;
macrolide antibiotic		antibacterial drug;
bacterial metabolite		00low000000
streptogramin a
0
1,3-oxazoles;
cyclic ketone;
enamide;
lactam;
macrolide antibiotic;
macrolide;
pyrroline;
secondary alcohol;
secondary carboxamide;
tertiary carboxamide		antibacterial drug;
Mycoplasma genitalium metabolite		00low000000
ceftriaxone
0
1,2,4-triazines;
1,3-thiazoles;
cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen;
EC 3.5.2.6 (beta-lactamase) inhibitor		00low000000
cefepime
0
cephalosporin;
oxime O-ether		antibacterial drug00low000000
ceftazidime
0
cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen;
EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor		00low000000
cefotaxime
0
1,3-thiazoles;
cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen		00low000000
aztreonam
0
beta-lactam antibiotic allergen;
monobactam		antibacterial drug;
drug allergen;
EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor		00low000000
cefpodoxime
0
carboxylic acid;
cephalosporin		antibacterial drug00low000000
cefuzonam
0
cephalosporinantibacterial drug00low000000
cefatrizine
0
amino acid amide;
carboxylic acid;
cephalosporin;
phenols;
semisynthetic derivative;
triazoles		antibacterial drug;
EC 2.7.11.20 (elongation factor 2 kinase) inhibitor		00low000000
cefditoren pivoxil
0
1,3-thiazoles;
cephams;
oxime O-ether;
pivaloyloxymethyl ester		antibacterial drug;
prodrug		00low000000
demycarosylturimycin h
0
aldehyde;
disaccharide derivative;
ether;
macrolide;
tertiary amino compound		antibacterial drug;
antimicrobial agent;
bacterial metabolite		00low000000
azlocillin
0
penicillin allergen;
penicillin;
semisynthetic derivative		antibacterial drug00low000000
cefpodoxime proxetil
0
carboxylic acid;
carboxylic ester;
cephalosporin		antibacterial drug;
prodrug		00low000000
ceftizoxime
0
cephalosporinantibacterial drug00low000000
carumonam
0
monobactamantibacterial drug00low000000
nitrofurantoin
0
imidazolidine-2,4-dione;
nitrofuran antibiotic;
organonitrogen heterocyclic antibiotic;
organooxygen heterocyclic antibiotic		antibacterial drug;
antiinfective agent;
hepatotoxic agent		00low000000
cefdinir
0
cephalosporin;
ketoxime		antibacterial drug00low000000
fumagillin
0
antibiotic antifungal drug;
carboxylic ester;
dicarboxylic acid monoester;
meroterpenoid;
organooxygen heterocyclic antibiotic;
spiro-epoxide		angiogenesis inhibitor;
antibacterial drug;
antimicrobial agent;
antiprotozoal drug;
fungal metabolite;
methionine aminopeptidase 2 inhibitor		00low000000
cefmenoxime
0
cephalosporinantibacterial drug00low000000
nifurtoinol
0
hydrazone;
imidazolidine-2,4-dione;
nitrofuran antibiotic;
organonitrogen heterocyclic antibiotic		antibacterial drug;
antiinfective agent;
hepatotoxic agent		00low000000
ru 29246
0
cephalosporinantibacterial drug00low000000
gemifloxacin
0
1,8-naphthyridine derivative;
fluoroquinolone antibiotic;
monocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antimicrobial agent;
topoisomerase IV inhibitor		00low000000
avibactam
0
azabicycloalkane;
hydroxylamine O-sulfonic acid;
monocarboxylic acid amide;
ureas		antibacterial drug;
antimicrobial agent;
EC 3.5.2.6 (beta-lactamase) inhibitor		00low000000
ppi-0903
0
1,3-thiazoles;
cephalosporin;
iminium betaine;
organic phosphoramidate;
oxime O-ether;
thiadiazoles		antibacterial drug;
antimicrobial agent;
prodrug		00low000000
cefditoren
0
carboxylic acid;
cephalosporin		antibacterial drug00low000000
penamecillin
0
penicillanic acid ester;
semisynthetic derivative		antibacterial drug;
prodrug		00low000000
streptogramin b
0
cyclodepsipeptideantibacterial drug;
antimicrobial agent;
bacterial metabolite		00low000000
l 749345
0
organic sodium saltantibacterial drug00low000000
finafloxacin
0
cyclopropanes;
monocarboxylic acid;
nitrile;
organofluorine compound;
quinolone;
secondary amino compound;
tertiary amino compound		antibacterial drug;
antimicrobial agent		00low000000
ly-146032
0
heterodetic cyclic peptide;
lipopeptide antibiotic;
lipopeptide;
macrocycle;
macrolide		antibacterial drug;
bacterial metabolite;
calcium-dependent antibiotics		00low000000
dalbavancin
0
carbohydrate acid derivative;
glycopeptide;
monosaccharide derivative;
semisynthetic derivative		antibacterial drug;
antimicrobial agent		00low000000
oritavancin
0
disaccharide derivative;
glycopeptide;
semisynthetic derivative		antibacterial drug;
antimicrobial agent		00low000000
ristocetin
0
glycopeptide;
heterodetic cyclic peptide;
macrocycle;
tetrasaccharide derivative		antibacterial drug;
antimicrobial agent;
bacterial metabolite;
platelet-activating factor receptor agonist		00low000000
clavulanate potassium
0
potassium saltantibacterial drug;
antimicrobial agent;
EC 3.5.2.6 (beta-lactamase) inhibitor		00low000000
cefamandole nafate
0
organic sodium saltantibacterial drug;
prodrug		00low000000
cefamandole nafate
0
organic sodium saltantibacterial drug00low000000
cephapirin sodium
0
cephalosporin;
organic sodium salt		antibacterial drug00low000000
nxl 104
0
organic sodium saltantibacterial drug;
antimicrobial agent;
EC 3.5.2.6 (beta-lactamase) inhibitor		00low000000
gamithromycin
0
macrolide antibiotic;
monosaccharide derivative		antibacterial drug;
protein synthesis inhibitor		00low000000
opt 80
0
carboxylic ester;
glycoside;
macrolide antibiotic;
organochlorine compound;
phenols		antibacterial drug;
bacterial metabolite;
EC 2.7.7.6 (RNA polymerase) inhibitor		00low000000
cefiderocol
0
carboxylic acid;
cephalosporin		antibacterial drug;
siderophore		00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
cephaloridine
0
beta-lactam antibiotic allergen;
cephalosporin;
semisynthetic derivative		antibacterial drug00low000000
cephalothin
0
azabicycloalkene;
beta-lactam antibiotic allergen;
carboxylic acid;
cephalosporin;
semisynthetic derivative;
thiophenes		antibacterial drug;
antimicrobial agent		00low000000
cephalexin
0
beta-lactam antibiotic allergen;
cephalosporin;
semisynthetic derivative		antibacterial drug00low000000
cephapirin
0
cephalosporinantibacterial drug00low000000
cefazolin
0
beta-lactam antibiotic allergen;
cephalosporin;
tetrazoles;
thiadiazoles		antibacterial drug00low000000
cephradine
0
beta-lactam antibiotic allergen;
cephalosporin		antibacterial drug00low000000
cefmetazole
0
cephalosporinantibacterial drug00low000000
ceforanide
0
cephalosporinantibacterial drug00low000000
cefonicid
0
cephalosporinantibacterial drug00low000000
cefotiam
0
beta-lactam antibiotic allergen;
cephalosporin;
semisynthetic derivative		antibacterial drug00low000000
cefoperazone
0
cephalosporinantibacterial drug00low000000
moxalactam
0
cephalosporin;
oxacephem		antibacterial drug00low000000
cefadroxil anhydrous
0
cephalosporinantibacterial drug00low000000
cefaclor anhydrous
0
cephalosporinantibacterial drug;
drug allergen		00low000000
cefprozil
0
cephalosporin;
semisynthetic derivative		antibacterial drug00low000000
cefaloram
0
cephalosporinantibacterial drug00low000000
cefazedone
0
4-pyridones;
carboxylic acid;
cephalosporin;
semisynthetic derivative;
thiadiazoles		antibacterial drug00low000000
cefoxitin
0
beta-lactam antibiotic allergen;
cephalosporin;
cephamycin;
semisynthetic derivative		antibacterial drug00low000000
cefamandole
0
cephalosporin;
semisynthetic derivative		antibacterial drug00low000000
cefpiramide
0
carboxylic acid;
cephalosporin		antibacterial drug00low000000
cefsulodin
0
cephalosporin;
organosulfonic acid;
primary carboxamide		antibacterial drug00low000000
7432 s
0
cephalosporin;
dicarboxylic acid		antibacterial drug00low000000
cefodizime
0
1,3-thiazoles;
cephalosporin;
oxime O-ether		antibacterial drug;
EC 1.14.18.1 (tyrosinase) inhibitor		00low000000
cefixime
0
cephalosporinantibacterial drug;
drug allergen		00low000000
streptogramin a
0
1,3-oxazoles;
cyclic ketone;
enamide;
lactam;
macrolide antibiotic;
macrolide;
pyrroline;
secondary alcohol;
secondary carboxamide;
tertiary carboxamide		antibacterial drug;
Mycoplasma genitalium metabolite		00low000000
ceftriaxone
0
1,2,4-triazines;
1,3-thiazoles;
cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen;
EC 3.5.2.6 (beta-lactamase) inhibitor		00low000000
cefepime
0
cephalosporin;
oxime O-ether		antibacterial drug00low000000
ceftazidime
0
cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen;
EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor		00low000000
cefotaxime
0
1,3-thiazoles;
cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen		00low000000
cefpodoxime
0
carboxylic acid;
cephalosporin		antibacterial drug00low000000
cefuzonam
0
cephalosporinantibacterial drug00low000000
cefatrizine
0
amino acid amide;
carboxylic acid;
cephalosporin;
phenols;
semisynthetic derivative;
triazoles		antibacterial drug;
EC 2.7.11.20 (elongation factor 2 kinase) inhibitor		00low000000
cefditoren pivoxil
0
1,3-thiazoles;
cephams;
oxime O-ether;
pivaloyloxymethyl ester		antibacterial drug;
prodrug		00low000000
cefpodoxime proxetil
0
carboxylic acid;
carboxylic ester;
cephalosporin		antibacterial drug;
prodrug		00low000000
ceftizoxime
0
cephalosporinantibacterial drug00low000000
cefdinir
0
cephalosporin;
ketoxime		antibacterial drug00low000000
cefmenoxime
0
cephalosporinantibacterial drug00low000000
ru 29246
0
cephalosporinantibacterial drug00low000000
ppi-0903
0
1,3-thiazoles;
cephalosporin;
iminium betaine;
organic phosphoramidate;
oxime O-ether;
thiadiazoles		antibacterial drug;
antimicrobial agent;
prodrug		00low000000
cefditoren
0
carboxylic acid;
cephalosporin		antibacterial drug00low000000
cephapirin sodium
0
cephalosporin;
organic sodium salt		antibacterial drug00low000000
cefiderocol
0
carboxylic acid;
cephalosporin		antibacterial drug;
siderophore		00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
gatifloxacin
1
N-arylpiperazine;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone		antiinfective agent;
antimicrobial agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor		2009200915.0low000100
penicillin g
1
penicillin allergen;
penicillin		antibacterial drug;
drug allergen;
epitope		2009200915.0low000100
cephalothin
1
azabicycloalkene;
beta-lactam antibiotic allergen;
carboxylic acid;
cephalosporin;
semisynthetic derivative;
thiophenes		antibacterial drug;
antimicrobial agent		2009200915.0low000100
ampicillin
2
beta-lactam antibiotic;
penicillin allergen;
penicillin		antibacterial drug2008200915.5low000200
amoxicillin
2
penicillin allergen;
penicillin		antibacterial drug2008200915.5low000200
cefaclor anhydrous
1
cephalosporinantibacterial drug;
drug allergen		2009200915.0low000100
cefprozil
2
cephalosporin;
semisynthetic derivative		antibacterial drug2008200915.5high000200
fropenem
1
faropenem2009200915.0low000100
ljc 10627
1
carbapenems;
organic sulfide;
pyrazolotriazole		antibacterial drug2009200915.0low000100
sanfetrinem
1
2009200915.0low000100
panipenem
1
organic molecular entity2009200915.0low000100
imipenem, anhydrous
1
beta-lactam antibiotic allergen;
carbapenems;
zwitterion		antibacterial drug2009200915.0low000100
garenoxacin
1
aromatic ether;
cyclopropanes;
isoindoles;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone antibiotic		antibacterial drug;
non-steroidal anti-inflammatory drug		2009200915.0low000100
levofloxacin
1
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid;
fluoroquinolone antibiotic;
quinolone antibiotic		antibacterial drug;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
topoisomerase IV inhibitor		2009200915.0low000100
meropenem
1
alpha,beta-unsaturated monocarboxylic acid;
carbapenemcarboxylic acid;
organic sulfide;
pyrrolidinecarboxamide		antibacterial agent;
antibacterial drug;
drug allergen		2009200915.0low000100
ly 163892
1
carbacephem;
zwitterion		antibacterial drug;
antimicrobial agent		2009200915.0low000100
cefuroxime
2
3-(carbamoyloxymethyl)cephalosporin;
furans;
oxime O-ether		drug allergen2008200915.5low000200
ceftriaxone
1
1,2,4-triazines;
1,3-thiazoles;
cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen;
EC 3.5.2.6 (beta-lactamase) inhibitor		2009200915.0low000100
cefotaxime
1
1,3-thiazoles;
cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen		2009200915.0low000100
cefpodoxime
2
carboxylic acid;
cephalosporin		antibacterial drug2008200915.5medium000200
nitrocefin
1
2009200915.0low000100
cefditoren pivoxil
2
1,3-thiazoles;
cephams;
oxime O-ether;
pivaloyloxymethyl ester		antibacterial drug;
prodrug		2008200915.5medium000200
cefdinir
2
cephalosporin;
ketoxime		antibacterial drug2008200915.5medium000200
tebipenem
2
2008200915.5low000200
rwj 54428
1
2009200915.0medium000100
ceftobiprole
1
cephalosporin;
thiadiazoles		antimicrobial agent2009200915.0low000100
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
carnitine
2
amino-acid betainehuman metabolite;
mouse metabolite		1992199232.0low102000
pivalic acid
2
branched-chain saturated fatty acid;
methyl-branched fatty acid;
short-chain fatty acid		1992199232.0low102000
cephalosporin c
5
cephalosporinfungal metabolite1992199331.6medium105000
s 1108
4
1992199331.5medium104000
pivaloylcarnitine
2
C5-acylcarnitinemetabolite1992199232.0medium102000
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
Bacterial Disease0
2
1993199331.0high002000
Bacterial Infections1
2
1993199331.0high002000
Eosinophilia0
1
1993199331.0medium001000
Eosinophilia, Tropical0
1
1993199331.0medium001000

Safety/Toxicity (1)

ArticleYear
Phase I clinical studies of S-1108: safety and pharmacokinetics in a multiple-administration study with special emphasis on the influence on carnitine body stores.
Antimicrobial agents and chemotherapy, , Volume: 36, Issue:4		1992

Pharmacokinetics (2)

ArticleYear
[Pharmacokinetic and clinical studies of S-1108 in the pediatric field].
The Japanese journal of antibiotics, , Volume: 46, Issue:11		1993
Phase I clinical studies of S-1108: safety and pharmacokinetics in a multiple-administration study with special emphasis on the influence on carnitine body stores.
Antimicrobial agents and chemotherapy, , Volume: 36, Issue:4		1992

Dosage (1)

ArticleYear
[Pharmacokinetic and clinical studies of S-1108 in the pediatric field].
The Japanese journal of antibiotics, , Volume: 46, Issue:11		1993