Page last updated: 2024-09-28

Fecal Impaction

Formation of a firm impassable mass of stool in the RECTUM or distal COLON.

Synonyms(3)

Synonym
Feces, Impacted
Fecal Impaction
Fecalith

Research Excerpts

Overview

ExcerptReference
"If the fecal impaction is not promptly relieved, the condition can lead to colonic perforation, peritonitis, and patient demise."( Heffernan, C; Macari, M; Megibow, AJ; Pachter, HL, 2005)

Treatment

ExcerptReference
"High fecal impaction resulted in complete bowel obstruction in 2 children following renal transplantation and in one adult on chemotherapy and narcotics."( Culp, WC, 1975)

Research

Studies (166)

TimeframeStudies, This Condition (%)All Conditions %
pre-199055 (33.13)23.3326
1990's36 (21.69)12.5806
2000's39 (23.49)18.1394
2010's33 (19.88)28.8240
2020's3 (1.81)9.53
DrugIndicatedRelationship StrengthStudiesTrials
methane0low10
citric acid, anhydrous0low10
chlorine0medium21
guaiacol0low10
creatine0low10
lactic acid0low10
glycerol0low10
hydrogen carbonate0medium11
iodine0low30
urea0low10
acetaminophen0low10
albuterol0low10
diatrizoic acid0low40
amitriptyline0low20
verapamil0low20
ciprofloxacin0low10
cisapride0medium21
clomipramine0low10
clonidine0low20
desipramine0low10
furosemide0low20
gentamicin0low10
guaifenesin0low20
halothane0low10
lidocaine0low20
iohexol0low10
ketoprofen0low10
maprotiline0low10
methadone0low10
metronidazole0low10
nifedipine0low10
perphenazine0low10
practolol0low10
risperidone0low10
sulfamethazine0low10
viloxazine0low10
xylazine0low20
prednisolone0low10
cephaloridine0low10
pilocarpine0low10
chloramphenicol0low10
galactose0low10
carbostyril0low10
levodopa0low10
ampicillin0low10
cyclizine0low10
framycetin0low20
diatrizoate meglumine0medium31
calcium gluconate0low10
docusate0medium11
glycopyrrolate0low10
acetylcysteine0low70
paraquat0low10
flupenthixol0low10
lanthanum0low20
technetium0low10
gold0low10
magnesium sulfate0low20
phosphoric acid, trisodium salt0low10
barium sulfate0low250
clonixin0low30
amitraz0low20
flunixin meglumine0low30
paroxetine0low10
captopril0low10
topotecan0low10
technetium tc 99m mertiatide0low10
aripiprazole0low10
cephalosporin c0low10
delphinidin0low10
fluorodeoxyglucose f180low10
picosulfate sodium0low10
tianeptine0low10
docetaxel anhydrous0low10
lactitol0low10
lubiprostone0low20
lanthanum carbonate0low20
benzofurans0medium21
pentazocine0low10
erythromycin estolate0medium11
cocaine0low10
buprenorphine0low10
D-fructopyranose0low10
pica0low90
prucalopride0medium21
bilirubin0low10
alprostadil0low20
morphine0low80
barium0low30
bismuth0low10
naltrexone0low10
methylnaltrexone0low10
phosphorus0low10
heroin0low10
magnesium citrate0low10
oxalates0low10
aluminum hydroxide, magnesium hydroxide, drug combination0low10
morphinans0low10
lactulose0medium123
td-51080medium21
ceftiofur0low10
bismuth subsalicylate0low10
sodium pertechnetate tc 99m0low10
piperidines0low10
salicylates0low10
kaolinite0low10
technetium tc 99m medronate0low20
clozapine0low100
tegaserod0low10
cholestyramine resin0low20

Protein Targets (932)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
RAR-related orphan receptor gamma230023
ATAD5 protein, partial110011
GLS protein120012
Microtubule-associated protein tau100010
Smad35005
aldehyde dehydrogenase 1 family, member A1140014
thyroid stimulating hormone receptor110011
nuclear receptor subfamily 1, group I, member 3210021
progesterone receptor160016
EWS/FLI fusion protein160016
retinoic acid nuclear receptor alpha variant 1250025
retinoid X nuclear receptor alpha140014
estrogen-related nuclear receptor alpha190019
estrogen nuclear receptor alpha380038
peroxisome proliferator activated receptor gamma160016
aryl hydrocarbon receptor100010
chromobox protein homolog 1160016
thyroid hormone receptor beta isoform 2220022
peripheral myelin protein 22140014
cytochrome P450 3A4 isoform 1140014
Gamma-aminobutyric acid receptor subunit pi142117
ATP-binding cassette sub-family C member 3025025
Multidrug resistance-associated protein 4025026
Solute carrier family 22 member 60505
Carbonic anhydrase 120305
UDP-glucuronosyltransferase 1A90103
Bile salt export pump0707
Voltage-dependent calcium channel gamma-2 subunit110011
Bile salt export pump035035
Cytochrome P450 2B10001
Cytochrome P450 1A10001
Carbonic anhydrase 109011
Carbonic anhydrase 209011
Myoglobin0101
Cytochrome P450 1A10012
Cytochrome P450 1A20203
Prostaglandin G/H synthase 10303
Carbonic anhydrase 30304
Cytochrome P450 3A4013217
Cytochrome P450 2D609011
Cytochrome P450 2C9 011012
Polyunsaturated fatty acid lipoxygenase ALOX150303
Gamma-aminobutyric acid receptor subunit beta-1142117
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta142117
Gamma-aminobutyric acid receptor subunit gamma-2142117
UDP-glucuronosyltransferase 1-60001
Glutamate receptor 2110011
Gamma-aminobutyric acid receptor subunit alpha-5142117
Gamma-aminobutyric acid receptor subunit alpha-3142117
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0002
Carbonic anhydrase 40709
Prostaglandin G/H synthase 10303
Carbonic anhydrase 60406
Gamma-aminobutyric acid receptor subunit gamma-1142117
Gamma-aminobutyric acid receptor subunit alpha-2142117
Gamma-aminobutyric acid receptor subunit alpha-4142117
Gamma-aminobutyric acid receptor subunit gamma-3142117
Gamma-aminobutyric acid receptor subunit alpha-6142117
Carbonic anhydrase 5A, mitochondrial0406
Prostaglandin G/H synthase 20405
Carbonic anhydrase 70305
Nuclear receptor ROR-gamma3003
Cytochrome P450 2J2010011
Gamma-aminobutyric acid receptor subunit alpha-1142117
Gamma-aminobutyric acid receptor subunit beta-3142117
Gamma-aminobutyric acid receptor subunit beta-2142117
Carbonic anhydrase 90406
GABA theta subunit142117
Canalicular multispecific organic anion transporter 1024024
Carbonic anhydrase 150304
Carbonic anhydrase 130204
Gamma-aminobutyric acid receptor subunit epsilon142117
Carbonic anhydrase 140305
Carbonic anhydrase 5B, mitochondrial0406
toxin B0001
Chain A, JmjC domain-containing histone demethylation protein 3A8008
Chain A, 2-oxoglutarate Oxygenase9009
Chain A, ATP-DEPENDENT DNA HELICASE Q14004
acetylcholinesterase130013
dopamine D1 receptor2002
15-lipoxygenase, partial4004
pregnane X receptor3003
phosphopantetheinyl transferase6006
USP1 protein, partial9009
NFKB1 protein, partial7007
Thrombopoietin8008
AR protein320032
regulator of G-protein signaling 49009
glucocorticoid receptor [Homo sapiens]180018
farnesoid X nuclear receptor170017
vitamin D (1,25- dihydroxyvitamin D3) receptor170017
arylsulfatase A110011
euchromatic histone-lysine N-methyltransferase 2230023
Bloom syndrome protein isoform 14004
D(1A) dopamine receptor100010
thyroid hormone receptor beta isoform a5005
heat shock protein beta-17007
flap endonuclease 17007
geminin210021
survival motor neuron protein isoform d8008
muscarinic acetylcholine receptor M1140014
Histone deacetylase 30101
Histone deacetylase 40101
Guanine nucleotide-binding protein G2002
Histone deacetylase 10101
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Ataxin-2140014
Histone deacetylase 80101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
ATP-dependent phosphofructokinase110011
glp-1 receptor, partial5005
thioredoxin reductase140014
NPYLR7B0022
thyroid stimulating hormone receptor150015
Beta-2 adrenergic receptor0336
Beta-1 adrenergic receptor0134
60 kDa chaperonin0101
60 kDa heat shock protein, mitochondrial0202
Beta-3 adrenergic receptor0123
Delta-type opioid receptor0539
10 kDa heat shock protein, mitochondrial0202
Thiosulfate sulfurtransferase0202
Beta-2 adrenergic receptor 0024
60 kDa chaperonin 0202
10 kDa chaperonin 0202
Beta-2 adrenergic receptor0236
TDP1 protein230023
Cellular tumor antigen p53180018
Thromboxane-A synthase 0202
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP1 subtype0101
Prostacyclin receptor0112
Nuclear receptor subfamily 4 group A member 20011
Solute carrier organic anion transporter family member 2A10102
Nuclear receptor subfamily 4 group A member 20011
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier organic anion transporter family member 2A10001
Solute carrier organic anion transporter family member 2B10101
Solute carrier organic anion transporter family member 3A10001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE150015
hypoxia-inducible factor 1 alpha subunit8008
GLI family zinc finger 3240024
cytochrome P450 family 3 subfamily A polypeptide 4200020
pregnane X nuclear receptor200020
cytochrome P450 2D6220022
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a100010
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a9009
v-jun sarcoma virus 17 oncogene homolog (avian)150015
potassium voltage-gated channel subfamily H member 2 isoform d120012
nuclear factor erythroid 2-related factor 2 isoform 1220022
lamin isoform A-delta10170017
Alpha-2A adrenergic receptor023226
Peroxisome proliferator-activated receptor alpha1001
Chain A, HADH2 protein9009
Chain B, HADH2 protein9009
cytochrome P450 2D6 isoform 1120012
atrial natriuretic peptide receptor 2 precursor7007
serine/threonine-protein kinase mTOR isoform 18008
Solute carrier family 22 member 1 012014
Polyunsaturated fatty acid lipoxygenase ALOX15B9009
Voltage-dependent L-type calcium channel subunit alpha-1F011011
5-hydroxytryptamine receptor 4022325
Albumin0044
High affinity nerve growth factor receptor0123
Aldo-keto reductase family 1 member B1012012
Muscarinic acetylcholine receptor M2018221
Muscarinic acetylcholine receptor M4016118
Muscarinic acetylcholine receptor M109010
Muscarinic acetylcholine receptor M30809
Muscarinic acetylcholine receptor M40809
5-hydroxytryptamine receptor 2C014014
Muscarinic acetylcholine receptor M50809
Muscarinic acetylcholine receptor M5017018
Muscarinic acetylcholine receptor M20809
Muscarinic acetylcholine receptor M1018322
Angiotensin-converting enzyme017018
D(2) dopamine receptor018225
5-hydroxytryptamine receptor 2A016016
Alpha-2B adrenergic receptor017119
Alpha-2C adrenergic receptor018120
5-hydroxytryptamine receptor 1A019120
Muscarinic acetylcholine receptor M3019121
D(1A) dopamine receptor014016
D(1B) dopamine receptor0608
UDP-glucuronosyltransferase 1A40003
Sodium-dependent noradrenaline transporter 016319
Histamine H2 receptor014014
Alpha-1D adrenergic receptor019121
5-hydroxytryptamine receptor 2A023025
5-hydroxytryptamine receptor 2C024125
5-hydroxytryptamine receptor 1B017017
5-hydroxytryptamine receptor 1D010010
5-hydroxytryptamine receptor 1F010010
5-hydroxytryptamine receptor 2B013114
5-hydroxytryptamine receptor 60404
Histamine H1 receptor0707
Sodium-dependent serotonin transporter020222
5-hydroxytryptamine receptor 7 0808
5-hydroxytryptamine receptor 5A0404
5-hydroxytryptamine receptor 5B0404
Histamine H1 receptor016220
D(3) dopamine receptor020226
Sodium channel protein type 1 subunit alpha0303
Sodium channel protein type 4 subunit alpha0404
UDP-glucuronosyltransferase 1A30004
5-hydroxytryptamine receptor 3A0707
5-hydroxytryptamine receptor 2B021122
Alpha-1A adrenergic receptor014216
Histamine H2 receptor123018
D(1A) dopamine receptor7108
5-hydroxytryptamine receptor 6011012
5-hydroxytryptamine receptor 70707
Voltage-dependent N-type calcium channel subunit alpha-1B0404
Sodium channel protein type 7 subunit alpha0303
Voltage-dependent L-type calcium channel subunit alpha-1D 011011
Sodium-dependent dopamine transporter 015217
Potassium voltage-gated channel subfamily H member 2026027
Voltage-dependent L-type calcium channel subunit alpha-1S011011
Voltage-dependent L-type calcium channel subunit alpha-1C012013
Sodium channel protein type 5 subunit alpha0808
Sodium channel protein type 9 subunit alpha0404
Sigma non-opioid intracellular receptor 10213
5-hydroxytryptamine receptor 4 0427
Nuclear receptor subfamily 3 group C member 3 014014
Sodium channel protein type 2 subunit alpha0303
Sigma non-opioid intracellular receptor 1015116
5-hydroxytryptamine receptor 3B0707
Sodium channel protein type 3 subunit alpha0404
Sodium channel protein type 11 subunit alpha0303
Sodium channel protein type 8 subunit alpha0303
Histamine H3 receptor0606
Sodium channel protein type 10 subunit alpha0303
Chain A, Mutant Al2 6e7p9g0011
Chain A, Beta-lactamase6006
Chain A, Cruzipain5005
Beta-lactamase 0001
acid sphingomyelinase1001
apical membrane antigen 1, AMA13003
Beta-lactamase 0002
Beta-lactamase 0001
Metallo-beta-lactamase type 20113
Metallo-beta-lactamase VIM-11 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
DNA polymerase beta2002
DNA polymerase eta isoform 12002
DNA polymerase iota isoform a (long)7007
DNA polymerase kappa isoform 15005
Beta-lactamase OXA-70001
Solute carrier family 15 member 10404
Solute carrier family 15 member 10202
Spike glycoprotein210122
Angiopoietin-1 receptor0011
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 15 member 20202
Metallo-beta-lactamase VIM-130001
Efflux transporter 0002
Beta-lactamase 0001
Beta-lactamase Toho-10002
Beta-lactamase 0002
Class D beta-lactamase0001
Metallo-beta-lactamase0001
Solute carrier family 15 member 20202
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-b-lactamase 0002
Carbapenem-hydrolyzing beta-lactamase KPC0002
Histamine H3 receptor0001
Beta-lactamase class B VIM-2 0114
Beta-lactamase VIM-1 0001
Chain A, TYROSYL-DNA PHOSPHODIESTERASE100010
5-hydroxytryptamine receptor 3E0404
SMAD family member 25005
Fumarate hydratase110011
PPM1D protein5005
SMAD family member 35005
estrogen receptor 2 (ER beta)100010
G8008
polyprotein110011
67.9K protein5005
peroxisome proliferator-activated receptor delta110011
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)3003
lysosomal alpha-glucosidase preproprotein2002
mu-type opioid receptor isoform MOR-10011
nuclear factor erythroid 2-related factor 2 isoform 23003
transcriptional regulator ERG isoform 33003
nuclear receptor ROR-gamma isoform 1110011
histone acetyltransferase KAT2A isoform 12002
5-hydroxytryptamine receptor 2A0011
neuropeptide S receptor isoform A2002
Solute carrier family 22 member 20404
5-hydroxytryptamine receptor 3A0213
5-hydroxytryptamine receptor 3B0404
Interferon beta130013
HLA class I histocompatibility antigen, B alpha chain 8008
ATP-dependent translocase ABCB109120
5-hydroxytryptamine receptor 1A08412
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Alpha-1B adrenergic receptor012113
D010010
D(4) dopamine receptor07112
Alpha-1D adrenergic receptor09110
D(4) dopamine receptor0606
Histamine H1 receptor0314
5-hydroxytryptamine receptor 70808
Alpha-1A adrenergic receptor08110
Alpha-1B adrenergic receptor0618
5-hydroxytryptamine receptor 3A0606
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0303
D(2) dopamine receptor013013
Inositol monophosphatase 17007
5-hydroxytryptamine receptor 3D0404
Multidrug and toxin extrusion protein 20303
5-hydroxytryptamine receptor 3C0404
Inositol hexakisphosphate kinase 18008
Multidrug and toxin extrusion protein 10606
cytochrome P450 2C9, partial8008
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
vitamin D3 receptor isoform VDRA5005
caspase-1 isoform alpha precursor1001
Caspase-71001
Solute carrier organic anion transporter family member 1B30405
Solute carrier organic anion transporter family member 1B10607
Luciferase110011
Kappa-type opioid receptor0809
Kappa-type opioid receptor08315
Chain A, angiotensin converting enzyme0101
Chain A, angiotensin converting enzyme0101
thioredoxin glutathione reductase2002
peripheral myelin protein 22 isoform 17007
M-phase phosphoprotein 86006
transient receptor potential cation channel subfamily V member 14004
Prothrombin0101
Renin0101
Neprilysin0101
Neprilysin0101
Leukotriene A-4 hydrolase0213
EEF1AKMT4-ECE2 readthrough transcript protein0101
Angiotensin-converting enzyme 0213
Leukotriene A-4 hydrolase0101
Thymidine phosphorylase0011
Endothelin-converting enzyme 10101
Succinyl-diaminopimelate desuccinylase0202
Angiotensin-converting enzyme0202
Beta-lactamase TEM0102
Mu-type opioid receptor0528
TAR DNA-binding protein 434004
Beta-lactamase 0203
Beta-lactamase 0202
Angiotensin-converting enzyme 2 0112
Chain A, serum paraoxonase0101
Neutrophil cytosol factor 10101
Carbonic anhydrase 130101
Poly [ADP-ribose] polymerase tankyrase-20101
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase0001
Nuclear receptor subfamily 1 group I member 20011
Solute carrier family 22 member 50101
Beta-lactamase0001
Beta-lactamase0001
Beta-lactamase SHV-10001
Beta-lactamase OXA-100001
Beta-lactamase0001
Beta-lactamase0001
Beta-lactamase0001
B2 metallo-beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 22 member 60303
Beta-lactamase 0001
Solute carrier family 22 member 70202
Beta-lactamase 0001
Beta-lactamase IMP-1 0001
Beta-lactamase 0001
Solute carrier family 22 member 80202
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 22 member 110101
Solute carrier family 22 member 80101
Solute carrier family 22 member 70101
interleukin 82002
activating transcription factor 69009
streptokinase A precursor0011
lethal factor (plasmid)8008
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60202
30S ribosomal protein S70202
50S ribosomal protein L150202
50S ribosomal protein L100202
50S ribosomal protein L110202
50S ribosomal protein L7/L120202
50S ribosomal protein L190202
50S ribosomal protein L10202
50S ribosomal protein L200202
50S ribosomal protein L270202
50S ribosomal protein L280202
50S ribosomal protein L290202
50S ribosomal protein L310202
50S ribosomal protein L31 type B0202
50S ribosomal protein L320202
50S ribosomal protein L330202
50S ribosomal protein L340202
50S ribosomal protein L350202
50S ribosomal protein L360202
30S ribosomal protein S100202
30S ribosomal protein S110202
30S ribosomal protein S120202
30S ribosomal protein S130202
30S ribosomal protein S160202
30S ribosomal protein S180202
30S ribosomal protein S190202
30S ribosomal protein S200202
30S ribosomal protein S20202
30S ribosomal protein S30202
30S ribosomal protein S40202
30S ribosomal protein S50202
30S ribosomal protein S80202
30S ribosomal protein S90202
50S ribosomal protein L130202
50S ribosomal protein L140202
50S ribosomal protein L160202
50S ribosomal protein L230202
30S ribosomal protein S150202
50S ribosomal protein L170202
50S ribosomal protein L210202
50S ribosomal protein L300202
50S ribosomal protein L60202
30S ribosomal protein S140202
30S ribosomal protein S170202
30S ribosomal protein S10202
50S ribosomal protein L180202
50S ribosomal protein L20202
50S ribosomal protein L30202
50S ribosomal protein L240202
50S ribosomal protein L40202
50S ribosomal protein L220202
50S ribosomal protein L50202
30S ribosomal protein S210202
50S ribosomal protein L250202
50S ribosomal protein L36 20202
Methionine--tRNA ligase, mitochondrial0011
Carbonic anhydrase0203
cytochrome P450 2C9 precursor6006
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0102
DNA gyrase subunit A0103
DNA gyrase subunit B0103
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0102
DNA topoisomerase 2-alpha0205
DNA gyrase subunit A0102
Cytochrome P450 2C190102
Multidrug resistance protein MdtK0011
DNA gyrase subunit B0101
DNA gyrase subunit A0101
Enoyl-[acyl-carrier-protein] reductase [NADH]0001
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Integrase 0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase0101
Dipeptidyl peptidase 40101
Insulin receptor 0101
Alpha-2B adrenergic receptor011112
Alpha-2C adrenergic receptor011112
Alpha-2A adrenergic receptor011112
Sodium-dependent dopamine transporter011011
Gastrin/cholecystokinin type B receptor0101
5-hydroxytryptamine receptor 406410
Neutral alpha-glucosidase AB0101
5-hydroxytryptamine receptor 2A0101
Heparanase0011
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50202
perilipin-10202
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0202
Beta-lactamase0101
Proto-oncogene tyrosine-protein kinase Src0101
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0001
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
caspase 7, apoptosis-related cysteine protease9009
caspase-39009
Histone H2A.x8008
Spike glycoprotein0011
Replicase polyprotein 1ab0011
cellular tumor antigen p53 isoform a6006
atrial natriuretic peptide receptor 1 precursor3003
mitogen-activated protein kinase 18008
Transmembrane protease serine 20011
Procathepsin L0011
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Trypanothione reductase0202
Trypanothione reductase0101
Proteasome subunit alpha type-60011
Envelope glycoprotein0022
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Chain A, Ferritin light chain1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
Beta-1 adrenergic receptor 0123
Alpha-1B adrenergic receptor 0011
cytochrome P450 2C19 precursor7007
Membrane primary amine oxidase 0101
Solute carrier family 22 member 30304
Alpha-1A adrenergic receptor0011
D(3) dopamine receptor0606
Amine oxidase [flavin-containing] A0101
D(1B) dopamine receptor0505
Amine oxidase [flavin-containing] B0101
Adenosine receptor A2b0011
Adenosine receptor A2a0113
Alpha-2B adrenergic receptor0001
Delta-type opioid receptor0518
Alpha-2C adrenergic receptor0001
Alpha-2A adrenergic receptor0001
Alpha-2A adrenergic receptor0101
Nischarin0202
Solute carrier family 22 member 10303
Nischarin0101
serine/threonine-protein kinase PLK12002
UDP-glucuronosyltransferase 2B70104
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
glucocerebrosidase5005
bromodomain adjacent to zinc finger domain 2B4004
IDH16006
Adenylate cyclase type 1 0202
short transient receptor potential channel 6 isoform 10011
Calmodulin-10101
Beta-2 adrenergic receptor0405
Beta-1 adrenergic receptor0315
D(2) dopamine receptor0404
Endothelin receptor type B0101
Adenylate cyclase type 30202
5-hydroxytryptamine receptor 3A0202
Endothelin receptor type B0101
Adenosine receptor A10203
Beta-3 adrenergic receptor0202
Adenylate cyclase type 20202
Adenylate cyclase type 40202
Sodium-dependent serotonin transporter09111
5-hydroxytryptamine receptor 2C 0303
5-hydroxytryptamine receptor 2A0303
Adenylate cyclase type 80202
5-hydroxytryptamine receptor 5A0101
D(2) dopamine receptor0202
D(3) dopamine receptor0202
Gastrin/cholecystokinin type B receptor0202
D(2) dopamine receptor0202
Calmodulin 0011
5-hydroxytryptamine receptor 2B0303
Adenylate cyclase type 60202
Adenylate cyclase type 50202
Transporter0303
Cholecystokinin receptor type A0202
5-hydroxytryptamine receptor 1A0202
Adenylyl cyclase 7 0202
D0303
ATPase family AAA domain-containing protein 56006
Histamine H4 receptor0112
Sigma non-opioid intracellular receptor 10314
Transporter0808
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Amyloid-beta precursor protein0101
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20112
Tryptophan 5-hydroxylase 10202
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Liver carboxylesterase 10002
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Glutamate receptor ionotropic, NMDA 1 0203
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit epsilon0101
Glutamate receptor ionotropic, NMDA 2A 0203
Glutamate receptor ionotropic, NMDA 2B0203
Glutamate receptor ionotropic, NMDA 2C0203
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Leukotriene B4 receptor 10102
Gamma-aminobutyric acid receptor subunit alpha-60101
Sodium-dependent dopamine transporter0303
Glutamate receptor ionotropic, NMDA 2D0203
Gamma-aminobutyric acid receptor subunit gamma-10101
Glutamate receptor ionotropic, NMDA 3B0203
Gamma-aminobutyric acid receptor subunit gamma-30101
Leukotriene B4 receptor 20102
Glutamate receptor ionotropic, NMDA 3A0203
Gamma-aminobutyric acid receptor subunit theta0101
Sodium- and chloride-dependent creatine transporter 10101
Proton-coupled amino acid transporter 10101
Epidermal growth factor receptor0303
Vascular endothelial growth factor receptor 20101
Alpha-synuclein0101
Lactoylglutathione lyase0202
Histone acetyltransferase p3000101
CREB-binding protein0101
huntingtin isoform 22002
Solute carrier family 22 member 30101
Albumin0325
Histamine H3 receptor0101
Solute carrier family 22 member 20101
Solute carrier family 22 member 40101
Hsf1 protein0011
nuclear receptor subfamily 1, group I, member 22002
Serum paraoxonase/arylesterase 10303
Kinesin-like protein KIF110101
Nucleotide-binding oligomerization domain-containing protein 20101
glycogen synthase kinase-3 alpha0001
Menin0011
Lecithin retinol acyltransferase0101
Lethal factor0101
Protein Rev 0011
Aminoglycoside 3'-phosphotransferase 0001
Tyrosyl-DNA phosphodiesterase 10101
thyrotropin-releasing hormone receptor1001
Glucose-6-phosphate 1-dehydrogenase0101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Adenosine receptor A10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
6-phosphogluconate dehydrogenase, decarboxylating0101
Holo-[acyl-carrier-protein] synthase0101
Sodium/bile acid cotransporter0101
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10202
Broad substrate specificity ATP-binding cassette transporter ABCG20415
importin subunit beta-1 isoform 13003
snurportin-13003
Beta-galactosidase0101
Lipopolysaccharide heptosyltransferase 10101
PA-I galactophilic lectin0011
Jacalin0011
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Integrin beta-34004
Integrin alpha-IIb4004
Rap guanine nucleotide exchange factor 32002
nonstructural protein 12002
Cocaine esterase0101
Transient receptor potential cation channel subfamily V member 10101
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Potassium channel subfamily K member 20213
Major prion protein0011
Vitamin D-binding protein0101
HLA class I histocompatibility antigen, A alpha chain 0011
Integrin beta-10101
Integrin alpha-40101
Carbonyl reductase [NADPH] 10001
C-8 sterol isomerase0101
Mu-type opioid receptor06211
Kappa-type opioid receptor0528
Mu-type opioid receptor010518
5-hydroxytryptamine receptor 2A0101
AP-2 complex subunit sigma0101
N-acetyltransferase Eis0202
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Calcitonin gene-related peptide type 1 receptor0101
Genome polyprotein 0202
Sigma intracellular receptor 20202
Sigma intracellular receptor 20202
Zinc finger protein 6640101
Vesicular acetylcholine transporter0101
Protease 0202
Transient receptor potential cation channel subfamily V member 40101
Transient receptor potential cation channel subfamily V member 20101
histone deacetylase 9 isoform 31001
GTP-binding nuclear protein Ran isoform 11001
GTP-binding protein (rab7)0011
ras protein, partial0011
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
Seed linoleate 13S-lipoxygenase-10101
Fatty acid-binding protein, intestinal0101
Aldo-keto reductase family 1 member B10101
Caspase-10101
Caspase-30101
Caspase-40101
Caspase-50101
Caspase-90101
Ras-related protein Rab-2A0011
Solute carrier organic anion transporter family member 1A30101
Prostaglandin G/H synthase 20101
Trans-sialidase0001
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
pyruvate kinase1001
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
Polyphenol oxidase 20001
Plasma kallikrein0001
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Tyrosinase0101
Carbonic anhydrase0001
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Carbonic anhydrase 0001
Carbonic anhydrase-like protein, putative0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Carbonic anhydrase 0001
Monocarboxylate transporter 100001
phosphoglycerate kinase1001
Potassium channel subfamily K member 30101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50202
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
NPC intracellular cholesterol transporter 1 precursor3003
histone-lysine N-methyltransferase NSD2 isoform 10001
ras-related protein Rab-9A4004
MBT domain-containing protein 10101
Lethal(3)malignant brain tumor-like protein 40101
Lethal(3)malignant brain tumor-like protein 30101
Lethal(3)malignant brain tumor-like protein 10101
Cytochrome P450 2B60101
Delta-type opioid receptor06413
Mas-related G-protein coupled receptor member X20022
Aldehyde oxidase 1 0202
Thioredoxin reductase 0101
muscleblind-like protein 1 isoform 12002
Flavodoxin0001
Lanosterol 14-alpha demethylase0101
Opioid receptor, delta 1b 0101
Acetylcholinesterase0101
Opioid receptor homologue0101
ATP-dependent translocase ABCB10202
Acyl-CoA desaturase 10101
Translocator protein0011
Histidine decarboxylase0022
ATP-dependent translocase ABCB10203
Proteinase-activated receptor 10112
Kappa-type opioid receptor0427
Mu-type opioid receptor0429
Nociceptin receptor0101
Mu-type opioid receptor0101
Mu-type opioid receptor0101
Nociceptin receptor0101
UDP-glucuronosyltransferase 1A80001
hypothetical protein, conserved1001
Parkin1001
beta-2 adrenergic receptor1001
tumor necrosis factor1001
polyunsaturated fatty acid lipoxygenase ALOX121001
eyes absent homolog 2 isoform a1001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
Glutathione reductase, mitochondrial0202
Adenosine receptor A30202
Phospholipase A2, membrane associated0001
Voltage-dependent L-type calcium channel subunit alpha-1C0202
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Platelet-activating factor receptor0001
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Indoleamine 2,3-dioxygenase 10101
Adenosine receptor A2a0101
Adenosine receptor A10202
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
C-C chemokine receptor type 20202
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Potassium voltage-gated channel subfamily A member 10101
C-terminal-binding protein 11001
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Myosin light chain kinase, smooth muscle0101
Transient receptor potential cation channel subfamily A member 10011
Potassium channel subfamily K member 2 0101
Indoleamine 2,3-dioxygenase 20101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Photosystem I iron-sulfur center 0001
Sodium-dependent noradrenaline transporter0101
Myeloperoxidase0101
Quinolone resistance protein NorA0101
Aldo-keto reductase family 1 member B10101
Beta-adrenergic receptor kinase 10101
Potassium voltage-gated channel subfamily A member 30202
Beta-adrenergic receptor kinase 10112
Substance-P receptor0101
Rhodopsin kinase GRK10101
G protein-coupled receptor kinase 50101
G protein-coupled receptor kinase 50101
P2X purinoceptor 40101
Rhodopsin kinase GRK10101
Sodium-dependent serotonin transporter0101
P2X purinoceptor 40101
Beta-adrenergic receptor kinase 10001
endonuclease IV1001
NADPH oxidase 10101
Snq2p0001
Caspase-71001
caspase-31001
ubiquitin-conjugating enzyme E2 N0101
protein AF-9 isoform a0001
bcl-2-related protein A10101
Vpr1001
DNA repair protein RAD52 homolog isoform a0001
Aldehyde oxidase 10101
Retinal dehydrogenase 10101
Pleiotropic ABC efflux transporter of multiple drugs0102
Disintegrin and metalloproteinase domain-containing protein 171001
Aldehyde oxidase0101
Aldehyde oxidase 10101
Rap guanine nucleotide exchange factor 41001
Cytochrome P450 2A60112
Muscarinic acetylcholine receptor M10011
Muscarinic acetylcholine receptor DM10101
Cytochrome P450 2A130112
Renin 0101
Beta-2 adrenergic receptor0101
Beta-2 adrenergic receptor0011
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Glucocorticoid receptor0218
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glycine receptor subunit alpha-10202
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Androgen receptor0101
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Nociceptin receptor0011
Estrogen receptor beta0202
Glycine receptor subunit alpha-10011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, 146aa long hypothetical transcriptional regulator0011
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain B, Anthranilate phosphoribosyltransferase0101
Chain C, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Anthranilate phosphoribosyltransferase0101
5-hydroxytryptamine receptor 1D0202
tyrosine-protein kinase Yes1001
DNA topoisomerase 10124
DNA topoisomerase 2-beta0101
DNA topoisomerase 10101
Hypoxia-inducible factor 1-alpha0112
Endothelial PAS domain-containing protein 10011
Urease subunit alpha0101
Urease subunit beta0101
Olfactory receptor 51E20011
Glycoprotein0101
Cytochrome P450 2C80101
Catechol O-methyltransferase0101
Multidrug resistance-associated protein 1 0214
Chloroquine resistance transporter0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]