Anhidrotic Ectodermal Dysplasia

A group of hereditary disorders involving tissues and structures derived from the embryonic ectoderm. They are characterized by the presence of abnormalities at birth and involvement of both the epidermis and skin appendages. They are generally nonprogressive and diffuse. Various forms exist, including anhidrotic and hidrotic dysplasias, FOCAL DERMAL HYPOPLASIA, and aplasia cutis congenita.

Synonym
Ectodermal Dysplasia, Anhydrotic
Ectodermal Dysplasia, Hidrotic, Autosomal Dominant
Clouston Hidrotic Ectodermal Dysplasia
Ectodermal Dysplasia, Hidrotic
Anhidrotic Ectodermal Dysplasia
Hidrotic Ectodermal Dysplasia, Autosomal Dominant
Anhydrotic Ectodermal Dysplasia
Hidrotic Ectodermal Dysplasia
Clouston Syndrome
Clouston's Hidrotic Ectodermal Dysplasia
Ectodermal Defect, Congenital
Autosomal Dominant Hidrotic Ectodermal Dysplasia
Clouston's Syndrome
Hydrotic Ectodermal Dysplasia
Congenital Ectodermal Defect
Ectodermal Dysplasia
Ectodermal Dysplasia 2, Hidrotic
Ectodermal Dysplasia Anhidrotic
Aplasia Cutis Congenita
Aplasia Cutis Congenita, Nonsyndromic
Defect, Congenital Ectodermal

Excerpt	Reference
"Ectodermal dysplasia is a rare group of diseases presenting special problems in management for the otolaryngologist, but the full spectrum of otorhinolaryngologic manifestations has been previously unrecognized in the otolaryngologic literature."	( Potsic, WP; Siegel, MB, 1990)
"Clouston syndrome is an hidrotic form of ectodermal dysplasia, inherited as an autosomal dominant trait with high penetrance."	( Guttmacher, AE; Hayflick, SJ; Litt, M; McKinnon, W; Taylor, T; Zonana, J, 1996)
"Aplasia cutis congenita is a condition that can present with a wide variety of symptoms and many attempts have been made to classify it comprehensively."	( Moss, AL; Uppal, RS, 2000)
"Two cases of aplasia cutis congenita are reported here."	( Agrawal, BB; Bhatia, BD; Kumar, A, 2000)
"Aplasia cutis congenita is a rare disorder characterized by developmental absence of skin on the scalp as multiple or solitary, noninflammatory, well demarcated, oval or circular 1- to 2-cm ulcers."	( Caksen, H; Kurtoglu, S, 2002)
"Cutis aplasia (or aplasia cutis congenita) is a congenital absence of all skin layers, often extending through bone."	( Buchman, SR; Colville, C; Muraszko, K; Rhee, ST, 2002)
"Aplasia cutis congenita is a rare condition characterized by the congenital absence of skin."	( Arai, H; Ichida, M; Inoue, M; Komuro, Y; Miyajima, M; Sato, K; Seno, H; Yanai, A, 2002)
"Ectodermal dysplasia is a hereditary condition in which hypodontia is the second most frequently occurring sign."	( Brahim, JS; Guckes, AD; King, TS; McCarthy, GR; Scurria, MS, 2002)
"Aplasia cutis congenita is characterised by congenital absence of all layers of skin, and most commonly affects the scalp."	( Canter, HI; Kayikcioglu, A; Nasir, S; Vargel, I, 2004)
"Aplasia cutis congenita is a rare condition characterized by the absence of skin layers."	( Giannetti, AV; Henriques, JG; Henriques, KS; Pianetti Filho, G, 2004)
"Hypohidrotic ectodermal dysplasia is a human syndrome defined by maldevelopment of one or more ectodermal-derived tissues, including the epidermis and cutaneous appendices, teeth, and exocrine glands."	( Bravo, A; Cascallana, JL; Donet, E; Jorcano, JL; Lara, MF; Leis, H; Paramio, JM; Pérez, P, 2005)
"Aplasia cutis congenita is a special condition, with local vascular abnormalities: local flaps are prohibited."	( Buis, J; Delbecque, M; Franchi, G; Picard, A; Sergent, B; Vazquez, MP, 2005)
"Ectodermal dysplasias are developmental disorders affecting tissues of ectodermal origin."	( Ahmad, W; Leal, SM; Lee, K; Naeem, M; Wajid, M, 2006)
"Aplasia cutis congenita is a rare congenital disorder of skin and most commonly involves the scalp."	( Bağdatoğlu, C; Başterzi, Y; Demirkan, F; Sari, A, 2007)
"Anhidrotic ectodermal dysplasia is a rare inherited disorder seen mainly in the X-linked recessive form."	( Soutou, B; Tomb, R; Zalloua, P, 2009)
"Ectodermal dysplasias are currently found in more than 150 syndromes."	( Soutou, B; Tomb, R; Zalloua, P, 2009)
"Clouston's syndrome is an ectodermal dysplasia characterized by dystrophic nails, alopecia, and palmoplantar hyperkeratosis."	( Dhurat, RS; Jerajani, HR; Melkote, S; Palav, A, 2009)
"Ectodermal dysplasias are heterogeneous heritable conditions characterized by congenital defects of one or more ectodermal structures and their appendages."	( Itin, PH, 2009)
"Aplasia cutis congenita is a rare congenital condition characterised by the absence of some or all layers of the skin."	( Carter, M; O'Neill, JK; Warr, RP, 2010)
"Aplasia cutis congenita is a rare disorder characterized by absence of skin."	( Cavalheiro, S; Dutra, LB; Ferreira, LM; Kreniski, TM; Pereira, MD; Zanon, N, 2009)
"Aplasia cutis congenita is a rare skin condition characterized by the absence of localized or widespread areas of skin at birth."	( Ali, S; Butt, UA; Ejaz, A; Iftikhar, N, 2009)
"Aplasia cutis congenita is a rare scalp defect with occasional absence of underlying bone and dura."	( Bui, CJ; Singh, M; St-Hilaire, H, 2012)
"Ectodermal dysplasia is a group of congenital syndromes affecting a variety of ectodermal derivatives."	( Aberdam, D; Aberdam, E; Müller, FJ; Petit, I; Serror, L; Shalom-Feuerstein, R; van Bokhoven, H; Wiman, KG; Zhou, H, 2013)
"Aplasia cutis congenita is a rare anomaly presenting with the absence of skin."	( Dahmardehei, M, 2013)
"Aplasia cutis congenita is a rare, congenital disorder."	( Berezovsky, AB; Krieger, Y; Landau, D; Levy, A; Pagkalos, VA; Rosenberg, L; Shoham, Y; Silberstein, E; Silberstein, T, 2014)
"Aplasia cutis congenital is a rare condition presenting with localized or widespread congenital absence of skin, most commonly affecting the scalp."	( Burge, J; Lonie, S; Phua, Y, 2016)
"Ectodermal dysplasia is a clinically and genetically heterogeneous group of inherited disorders characterized by abnormal development of two or more of the following ectodermal-derived structures: hair, teeth, nails and sweat glands."	( Calvieri, S; Fortuna, MC; Giustini, S; Miraglia, E; Rossi, A, 2017)
"Aplasia cutis congenita is a rare congenital disorder characterised by the absence of skin."	( Rath, T; Steinbacher, J; Tzou, CH, 2016)
"Aplasia Cutis Congenita is a rare disorder with circumscribed, partial or widespread absence of skin and subcutaneous soft tissue; in about 20% it also causes skull defects."	( Chokoeva, A; Handjani, F; Tchernev, G; Verma, S; Wollina, U, 2017)
"Aplasia cutis congenita is defined as the absence of all layers of the skin."	( Charvillat, O; Gouron, R; Haraux, E; Klein, C; Plancq, MC; Tourneux, P, 2020)
"Aplasia cutis congenita is a rare but heterogeneous group of conditions characterized by the absence of one or more areas of skin sometimes extending to deeper tissues."	( Davison, WL; Feit, NZ; Modi, VK; Sclafani, AP, 2020)
"Aplasia cutis congenita is regarded as congenital focal absence of skin in the newborn, and occurrence of more than three similar skin defects is rare."	( Chandraratne, SH; Dayasiri, K; Thadchanamoorthy, V; Thamilvannan, N; Thirukumar, M, 2021)
"Aplasia cutis congenita is a rare condition of uncertain etiology, but consanguinity may play a role."	( Chandraratne, SH; Dayasiri, K; Thadchanamoorthy, V; Thamilvannan, N; Thirukumar, M, 2021)
"Aplasia cutis congenita is a heterogeneous disorders group with a rare reported incident of 0."	( Abdulwahab, AH; Al Nefily, RM; Al-Shammari, AA; AlAnazi, RA; AlMatrifi, FR; Ammar, AS, 2023)

Excerpt	Reference
"Aplasia cutis congenita affecting the elbows, knees, hips, and gluteal area was observed in a female newborn, product of a twin pregnancy."	( Cohen, RN; Dror, Y; Gelman-Kohan, Z; Hagai, Z; Juster-Reicher, A; Mogilner, B, 1994)

Excerpt	Reference
"A case of aplasia cutis congenita of the scalp with bony defect in a newborn treated by early excision and reconstruction is presented."	( Attalla, MF; el-Sayed, AM, 1992)
"Nine patients with aplasia cutis congenita were treated in our department during the past 30 years."	( Berger, J; Govrin, J; Moscona, R, 1991)
"We report a child with scalp aplasia cutis congenita, whose mother was treated with methimazole during pregnancy."	( Landthaler, M; Stolz, W; Vogt, T, 1995)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	117 (22.50)	23.3326
1990's	64 (12.31)	12.5806
2000's	134 (25.77)	18.1394
2010's	146 (28.08)	28.8240
2020's	59 (11.35)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	low	1	0
carbamates	low	1	0
chlorine	low	1	0
salicylic acid	low	182	0
cytosine	low	2	0
glycine	low	3	0
dalteparin	low	1	0
iodine	low	10	0
inositol	low	1	0
sulfites	low	1	0
thymine	low	2	0
urea	low	2	0
2,4,6-tribromophenol	low	1	0
phenytoin	low	1	0
arecoline	low	1	0
aspirin	low	1	0
azathioprine	low	2	0
baclofen	low	1	0
busulfan	low	1	0
cetirizine	low	1	0
chlorambucil	low	1	0
flecainide	low	1	0
fluconazole	low	1	0
flumazenil	low	1	0
gentamicin	low	3	0
guaifenesin	low	1	0
hydroxychloroquine	low	1	0
indomethacin	low	1	0
2-propanol	low	7	0
ketoconazole	medium	1	1
khellin	low	2	0
leflunomide	low	1	0
metformin	low	1	0
minoxidil	low	4	0
ofloxacin	low	1	0
phenolsulfonphthalein	low	1	0
sotalol	low	1	0
thalidomide	low	2	0
thiotepa	low	1	0
vigabatrin	low	1	0
prednisolone	low	1	0
thymidine	low	1	0
hydroxyproline	low	1	0
thyroxine	low	3	0
prednisolone acetate	low	1	0
prednisone	low	3	0
androsterone	low	1	0
pilocarpine	low	3	0
serine	low	5	0
glutamine	low	2	0
lysine	low	1	0
tyrosine	low	4	0
methicillin	low	1	0
leucine	low	2	0
phenylalanine	low	1	0
ampicillin	low	2	0
histidine	low	1	0
valine	low	1	0
tryptophan	low	2	0
isoleucine	low	2	0
arginine	low	9	0
phencyclidine	low	1	0
acedapsone	low	1	0
methylprednisolone	low	1	0
quinuclidines	low	3	0
tetraethyleneglycol dimethacrylate	low	1	0
isoxazoles	low	1	0
pyrazines	low	1	0
betamethasone	low	2	0
phenylpropanolamine	low	1	0
diphenylamine	low	2	0
ethylnitrosourea	low	1	0
nile blue	low	1	0
floxacillin	low	1	0
vidarabine	low	1	0
titanium	medium	4	1
acetylglucosamine	low	2	0
chromates	low	1	0
silver nitrate	low	2	0
trolamine salicylate	low	1	0
carbimazole	low	6	0
triamcinolone	low	1	0
etoposide	low	1	0
propiconazole	low	6	0
silver chromate	low	1	0
n-(7-dimethylamino-4-methylcoumarinyl)maleimide	low	1	0
pyridinoline	low	1	0
deoxypyridinoline	low	1	0
methotrexate	low	1	0
proline	low	6	0
biotin	low	2	0
ropivacaine	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	2	0
carboplatin	low	1	0
elastin	low	2	0
inositol 3-phosphate	low	10	0
tretinoin	low	3	0
retinol	low	4	0
zithromax	low	3	0
dactinomycin	low	1	0
melphalan	low	1	0
favipiravir	low	1	0
bromochloroacetic acid	low	52	0
leuprolide	low	1	0
fludarabine	low	1	0
propylthiouracil	low	3	0
methimazole	low	10	0
cystine	low	2	0
alpha-chymotrypsin	low	1	0
dinoprostone	low	1	0
etretinate	low	3	0
isotretinoin	low	2	0
phenylephrine hydrochloride	low	50	0
acitretin	low	4	0
sirolimus	low	1	0
deamino arginine vasopressin	low	1	0
lysophosphatidic acid	low	1	0
sulfur	low	6	0
cysteine	low	4	0
silicon	low	1	0
phosphorus	low	2	0
cefotaxime	low	1	0
pd 0325901	low	2	0
treosulfan	low	1	0
tofacitinib	low	1	0
pituitrin	low	1	0
jaw	low	3	0
hes1 protein, human	low	2	0
oligonucleotides	low	1	0
natriuretic peptide, c-type	low	1	0
calpain	low	1	0
sodium ethylxanthate	low	3	0
piperidines	low	1	0
apr-246	low	3	0
heparitin sulfate	low	1	0
epidermal growth factor	low	8	0
transforming growth factor beta	low	1	0
gsk-j4	low	1	0
feldspar	low	1	0
vitamin b 12	low	1	0
cyclosporine	low	1	0
chondroitin sulfates	low	1	0
exudates	low	1	0
acyclovir	low	1	0
guanine	low	3	0
rifampin	low	1	0
eye	low	10	0
trypsinogen	low	1	0

Protein Targets (1,555)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	15	0	0	15
RAR-related orphan receptor gamma	34	0	0	34
GLI family zinc finger 3	40	0	0	40
AR protein	45	0	0	45
aldehyde dehydrogenase 1 family, member A1	23	0	0	23
retinoic acid nuclear receptor alpha variant 1	34	0	0	34
retinoid X nuclear receptor alpha	31	0	0	31
estrogen nuclear receptor alpha	50	0	0	50
peroxisome proliferator-activated receptor delta	23	0	0	23
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	30	0	0	30
activating transcription factor 6	16	0	0	16
v-jun sarcoma virus 17 oncogene homolog (avian)	18	0	0	18
Histone H2A.x	14	0	0	14
thyroid hormone receptor beta isoform a	14	0	0	14
heat shock protein beta-1	16	0	0	16
nuclear factor erythroid 2-related factor 2 isoform 1	40	0	0	40
lamin isoform A-delta10	34	0	0	34
Voltage-dependent calcium channel gamma-2 subunit	19	0	0	19
Glutamate receptor 2	19	0	0	19
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	10	0	0	10
GLS protein	15	0	0	15
thyroid stimulating hormone receptor	14	0	0	14
estrogen receptor 2 (ER beta)	16	0	0	16
nuclear receptor subfamily 1, group I, member 3	29	0	0	29
progesterone receptor	24	0	0	24
cytochrome P450 family 3 subfamily A polypeptide 4	23	0	0	23
glucocorticoid receptor [Homo sapiens]	33	0	0	33
estrogen-related nuclear receptor alpha	41	0	0	41
farnesoid X nuclear receptor	21	0	0	21
pregnane X nuclear receptor	32	0	0	32
peroxisome proliferator activated receptor gamma	24	0	0	24
aryl hydrocarbon receptor	17	0	0	17
nuclear factor erythroid 2-related factor 2 isoform 2	15	0	0	15
thyroid hormone receptor beta isoform 2	27	0	0	27
geminin	37	0	0	37
cytochrome P450 3A4 isoform 1	16	0	0	16
Gamma-aminobutyric acid receptor subunit pi	16	5	0	21
Cellular tumor antigen p53	28	0	0	28
Gamma-aminobutyric acid receptor subunit beta-1	16	5	0	21
Gamma-aminobutyric acid receptor subunit delta	16	5	0	21
Gamma-aminobutyric acid receptor subunit gamma-2	16	5	1	22
Gamma-aminobutyric acid receptor subunit alpha-5	16	5	0	21
Gamma-aminobutyric acid receptor subunit alpha-3	16	5	0	21
Gamma-aminobutyric acid receptor subunit gamma-1	16	5	0	21
Gamma-aminobutyric acid receptor subunit alpha-2	16	5	0	21
Gamma-aminobutyric acid receptor subunit alpha-4	16	5	0	21
Gamma-aminobutyric acid receptor subunit gamma-3	16	5	0	21
Gamma-aminobutyric acid receptor subunit alpha-6	16	5	0	21
Nuclear receptor ROR-gamma	12	1	1	14
Gamma-aminobutyric acid receptor subunit alpha-1	16	6	1	23
Gamma-aminobutyric acid receptor subunit beta-3	16	5	0	21
Gamma-aminobutyric acid receptor subunit beta-2	16	5	1	22
Peroxisome proliferator-activated receptor alpha	1	0	0	1
TAR DNA-binding protein 43	12	0	0	12
GABA theta subunit	16	5	0	21
Gamma-aminobutyric acid receptor subunit epsilon	16	5	0	21
Putative glycosyltransferase WbgO	0	0	0	1
Cytochrome P450 3A4	0	10	2	14
Cannabinoid receptor 1	0	1	0	1
Killer cell lectin-like receptor subfamily B member 1A	0	1	0	1
Early activation antigen CD69	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	4	0	0	4
Luciferase	14	0	0	14
USP1 protein, partial	16	0	0	16
TDP1 protein	38	0	0	38
Microtubule-associated protein tau	12	0	0	12
euchromatic histone-lysine N-methyltransferase 2	37	0	0	37
vitamin D3 receptor isoform VDRA	14	0	0	14
flap endonuclease 1	11	0	0	11
serine/threonine-protein kinase PLK1	4	0	0	4
eyes absent homolog 2 isoform a	1	0	0	1
DNA polymerase eta isoform 1	5	0	0	5
peripheral myelin protein 22	18	0	0	18
survival motor neuron protein isoform d	15	0	0	15
histone acetyltransferase KAT2A isoform 1	13	0	0	13
ATP-binding cassette sub-family C member 3	0	32	0	32
Multidrug resistance-associated protein 4	0	32	0	34
Bile salt export pump	0	13	0	13
Bile salt export pump	0	45	0	45
Rap guanine nucleotide exchange factor 3	5	0	0	5
Rap guanine nucleotide exchange factor 4	2	0	0	2
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	9	0	0	9
Chain B, HADH2 protein	9	0	0	9
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
Chain A, Ferritin light chain	10	0	0	10
Thymidine kinase	0	2	0	3
thioredoxin reductase	28	0	0	28
phosphopantetheinyl transferase	17	0	0	17
Smad3	5	0	0	5
EWS/FLI fusion protein	24	0	0	24
arylsulfatase A	13	0	0	13
Bloom syndrome protein isoform 1	18	0	0	18
hemoglobin subunit beta	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
Solute carrier family 22 member 1	0	2	0	4
Solute carrier family 22 member 6	0	4	0	5
Purine nucleoside phosphorylase	0	3	0	3
Thymidine kinase, cytosolic	0	2	0	6
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2C9	0	9	1	10
Cytochrome P450 2J2	0	4	0	4
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	3	0	7
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	4	0	7
Canalicular multispecific organic anion transporter 1	0	32	0	33
Thymidine kinase	0	1	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	19	0	0	19
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
importin subunit beta-1 isoform 1	4	0	0	4
snurportin-1	4	0	0	4
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
Cyclin-dependent kinase 1	0	1	3	4
Heat shock protein HSP 90-beta	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	1	3
ATPase family AAA domain-containing protein 5	14	0	0	14
Ataxin-2	14	0	0	14
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, Beta-lactamase	4	0	0	4
Chain A, 2-oxoglutarate Oxygenase	11	0	0	11
Chain A, Cruzipain	8	0	0	8
Beta-lactamase	0	0	0	2
acid sphingomyelinase	2	0	0	2
apical membrane antigen 1, AMA1	5	0	0	5
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	2
Metallo-beta-lactamase VIM-11	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	8	0	0	8
chromobox protein homolog 1	19	0	0	19
DNA polymerase beta	2	0	0	2
DNA polymerase iota isoform a (long)	17	0	0	17
DNA polymerase kappa isoform 1	9	0	0	9
Carbonic anhydrase 1	0	8	0	14
Carbonic anhydrase 2	0	8	1	15
60 kDa heat shock protein, mitochondrial	0	3	0	3
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	4	0	4
Solute carrier family 15 member 1	0	1	0	1
Spike glycoprotein	9	0	1	10
10 kDa heat shock protein, mitochondrial	0	3	0	3
Angiopoietin-1 receptor	0	0	3	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	2	0	2
Thiosulfate sulfurtransferase	0	3	0	3
Metallo-beta-lactamase VIM-13	0	0	0	2
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
60 kDa chaperonin	0	3	0	3
Metallo-beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	2	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
10 kDa chaperonin	0	3	0	3
Metallo-b-lactamase	0	0	0	2
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	2
Histamine H3 receptor	0	0	0	2
Beta-lactamase class B VIM-2	0	0	0	2
Beta-lactamase VIM-1	0	0	0	2
ATP-dependent phosphofructokinase	16	0	0	16
Chain A, retinol dehydratase	0	1	0	1
acetylcholinesterase	10	0	0	10
Sex hormone-binding globulin	0	0	2	2
Corticosteroid-binding globulin	0	3	0	3
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
Androgen receptor	0	4	0	4
Solute carrier organic anion transporter family member 1A1	0	2	0	2
G-protein coupled bile acid receptor 1	0	0	1	1
PPM1D protein	7	0	0	7
Interferon beta	24	0	0	24
regulator of G-protein signaling 4	11	0	0	11
thyrotropin-releasing hormone receptor	2	0	0	2
Muscarinic acetylcholine receptor M2	0	7	2	9
Muscarinic acetylcholine receptor M4	0	3	1	4
Muscarinic acetylcholine receptor M1	0	4	1	7
Muscarinic acetylcholine receptor M3	0	4	1	7
Muscarinic acetylcholine receptor M4	0	4	1	7
Muscarinic acetylcholine receptor M5	0	4	1	7
Muscarinic acetylcholine receptor M5	0	4	1	5
Neuronal acetylcholine receptor subunit alpha-4	1	3	0	4
Muscarinic acetylcholine receptor M2	0	4	1	7
Muscarinic acetylcholine receptor M1	0	4	3	7
Neuronal acetylcholine receptor subunit beta-2	1	3	0	4
Muscarinic acetylcholine receptor M1	0	1	3	5
Muscarinic acetylcholine receptor M3	0	3	1	4
Inositol monophosphatase 1	3	0	0	3
Muscarinic acetylcholine receptor	0	1	0	1
Muscarinic acetylcholine receptor M3	0	0	2	4
Muscarinic acetylcholine receptor M2	0	0	1	4
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
NFKB1 protein, partial	4	0	0	4
alpha-galactosidase	2	0	0	2
cytochrome P450 2C19 precursor	6	0	0	6
muscarinic acetylcholine receptor M1	9	0	0	9
lethal factor (plasmid)	9	0	0	9
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	2
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	10	0	0	10
hypothetical protein, conserved	1	0	0	1
cytochrome P450 2D6	13	0	0	13
glucocerebrosidase	3	0	0	3
Rac1 protein	0	0	1	1
IDH1	11	0	0	11
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 1	0	3	0	4
Prostaglandin G/H synthase 2	0	3	0	4
Epidermal growth factor receptor	0	3	3	6
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	2	1	0	3
Myeloperoxidase	0	3	0	3
Prostaglandin G/H synthase 1	0	4	0	5
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	2	1	0	3
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Adenosine receptor A1	0	2	0	5
Adenosine receptor A2a	0	2	0	5
Substance-P receptor	0	3	0	3
Prostaglandin G/H synthase 2	0	6	2	8
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	4	0	4
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	3	0	3
Solute carrier family 22 member 20	0	4	0	4
Solute carrier family 22 member 6	0	4	0	4
Sigma non-opioid intracellular receptor 1	0	2	1	3
Sigma non-opioid intracellular receptor 1	0	2	1	3
SMAD family member 2	10	0	0	10
ATAD5 protein, partial	8	0	0	8
Fumarate hydratase	4	0	0	4
SMAD family member 3	10	0	0	10
thioredoxin glutathione reductase	7	0	0	7
G	16	0	0	16
polyprotein	4	0	0	4
P53	2	0	0	2
thyroid stimulating hormone receptor	11	0	0	11
peripheral myelin protein 22 isoform 1	10	0	0	10
cellular tumor antigen p53 isoform a	3	0	0	3
M-phase phosphoprotein 8	6	0	0	6
muscleblind-like protein 1 isoform 1	6	0	0	6
HLA class I histocompatibility antigen, B alpha chain	16	0	0	16
Inositol hexakisphosphate kinase 1	16	0	0	16
Protein-arginine deiminase type-4	0	4	0	4
cytochrome P450 2C9, partial	16	0	0	16
67.9K protein	8	0	0	8
D(1A) dopamine receptor	2	0	0	2
Gamma-aminobutyric acid type B receptor subunit 2	0	3	1	4
Gamma-aminobutyric acid type B receptor subunit 2	0	2	0	2
Gamma-aminobutyric acid type B receptor subunit 1	0	3	1	4
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
pregnane X receptor	8	0	0	8
vitamin D (1,25- dihydroxyvitamin D3) receptor	19	0	0	19
nuclear receptor subfamily 1, group I, member 2	6	0	0	6
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	12	2	19
Glycine receptor subunit alpha-1	0	12	0	12
Glycine receptor subunit beta	0	12	0	12
Glycine receptor subunit alpha-2	0	12	0	12
Glycine receptor subunit alpha-3	0	12	0	12
ORF73	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
15-lipoxygenase, partial	7	0	0	7
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	11	0	0	11
Matrix metalloproteinase-9	0	1	0	1
Lactoperoxidase	0	2	0	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	5	0	0	5
histone-lysine N-methyltransferase 2A isoform 2 precursor	5	0	0	5
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Albumin	0	3	4	7
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
Kappa-type opioid receptor	0	1	0	2
B2 metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 7	0	1	0	4
Beta-lactamase	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 11	0	1	0	3
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 22 member 7	0	1	0	2
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
Histamine H1 receptor	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	7	0	7
Multidrug and toxin extrusion protein 1	0	4	0	4
Histamine H4 receptor	0	1	0	1
GALC protein	4	0	0	4
Thrombopoietin	2	0	0	2
caspase 7, apoptosis-related cysteine protease	6	0	0	6
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	13	0	0	13
bromodomain adjacent to zinc finger domain 2B	5	0	0	5
caspase-3	6	0	0	6
potassium voltage-gated channel subfamily H member 2 isoform d	8	0	0	8
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
urokinase-type plasminogen activator precursor	6	0	0	6
plasminogen precursor	6	0	0	6
urokinase plasminogen activator surface receptor precursor	6	0	0	6
Carbonic anhydrase 12	0	2	0	6
Cytochrome P450 2D6	0	4	1	5
Carbonic anhydrase 9	0	2	0	6
Solute carrier organic anion transporter family member 1B3	0	8	0	10
Carbonic anhydrase 4	0	3	0	7
Carbonic anhydrase	0	2	0	6
Carbonic anhydrase 15	0	3	0	7
endonuclease IV	4	0	0	4
dopamine D1 receptor	2	0	0	2
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Deoxycytidine kinase	0	0	0	1
RAD51	0	1	0	1
Caspase-7	5	0	0	5
caspase-3	5	0	0	5
huntingtin isoform 2	2	0	0	2
nuclear receptor ROR-gamma isoform 1	11	0	0	11
caspase-1 isoform alpha precursor	2	0	0	2
ATP-dependent translocase ABCB1	0	7	0	9
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Caspase-7	2	0	0	2
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	1	0	1
Discoidin domain-containing receptor 2	0	1	3	4
Growth factor receptor-bound protein 2	0	1	0	1
Reverse transcriptase/RNaseH	0	1	0	1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	1	1	2
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
prostaglandin E2 receptor EP2 subtype	1	0	0	1
mitogen-activated protein kinase 1	3	0	0	3
Solute carrier family 22 member 2	0	1	0	2
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
ClpP	2	0	0	2
Glycoprotein hormones alpha chain	1	0	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	1
glp-1 receptor, partial	8	0	0	8
LMP1 [Human herpesvirus 4]	0	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	2	0	2
Prothrombin	0	0	0	1
Regulatory protein E2	0	0	1	1
ATP-dependent translocase ABCB1	0	4	0	4
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 2-alpha	0	1	4	10
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
DNA topoisomerase 2	0	0	0	1
ATP-dependent translocase ABCB1	0	4	0	4
UDP-glucuronosyltransferase 1A1	0	2	0	3
Serum paraoxonase/arylesterase 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	5	1	11
Caspase-3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	4	1	10
Glutamate receptor ionotropic, NMDA 2B	0	5	1	11
Glutamate receptor ionotropic, NMDA 2C	0	4	1	11
DNA topoisomerase 2-alpha	0	0	0	1
DNA topoisomerase 2-beta	0	1	4	11
Glutamate receptor ionotropic, NMDA 2D	0	4	1	10
Tubulin beta-2B chain	0	1	0	1
Integrase	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	4	1	10
Glutamate receptor ionotropic, NMDA 3A	0	4	1	10
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Sodium channel protein type 5 subunit alpha	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
unnamed protein product	0	1	0	1
transcriptional regulator ERG isoform 3	5	0	0	5
heat shock protein HSP 90-alpha isoform 2	0	0	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
Histone deacetylase 3	0	3	0	3
Chymotrypsinogen A	0	3	0	3
Beta-lactamase	0	2	0	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	3	0	3
Heme oxygenase 1	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	1	2
Aromatase	0	3	0	3
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Cytochrome P450 11B2, mitochondrial	0	2	0	2
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	2	0	2
Histone deacetylase 4	0	3	0	3
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Histone deacetylase 1	0	3	0	3
Lanosterol 14-alpha demethylase	0	5	2	7
Sterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	1	2
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	3	0	3
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	3	0	3
14-alpha sterol demethylase	0	0	1	1
Histone deacetylase 8	0	3	0	3
Histone deacetylase 6	0	3	0	3
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	3	0	3
heat shock protein 90, putative	0	0	0	2
likely tRNA 2'-phosphotransferase	0	1	0	1
corticotropin-releasing hormone receptor 2	0	1	1	2
corticotropin releasing factor-binding protein	0	1	1	2
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
5'-nucleotidase	0	1	0	1
Adenosine receptor A3	0	1	0	1
Adenosine deaminase	0	0	0	2
cytochrome P450 2D6 isoform 1	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
5-hydroxytryptamine receptor 1A	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	4	0	4
Asc-type amino acid transporter 1	0	2	0	2
Neutral amino acid transporter B(0)	0	4	0	4
Carbonic anhydrase-like protein, putative	0	0	0	5
Amino acid transporter	0	4	0	4
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	8	0	9
Proton-coupled amino acid transporter 1	0	6	0	7
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	1	2	3
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Lysine-specific demethylase 6A	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Guanine deaminase	0	1	0	2
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Plasma kallikrein	0	0	0	4
Carbonic anhydrase 3	0	1	0	5
Histidine-binding periplasmic protein	0	0	1	1
Carbonic anhydrase 6	0	1	0	5
5-hydroxytryptamine receptor 1D	0	0	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	5
Carbonic anhydrase 7	0	1	0	5
Carbonic anhydrase	0	0	0	4
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase 13	0	0	0	2
Carbonic anhydrase 4	0	0	0	1
Carbonic anhydrase 13	0	1	0	4
Carbonic anhydrase 14	0	1	0	5
Carbonic anhydrase 5B, mitochondrial	0	1	0	5
Genome polyprotein	0	1	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Procathepsin L	0	1	1	2
Alpha-2A adrenergic receptor	0	3	0	3
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Alpha-2B adrenergic receptor	0	5	0	5
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Parkin	4	0	0	4
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
cytochrome P450 2C9 precursor	5	0	0	5
ras-related protein Rab-9A	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
neuropeptide S receptor isoform A	2	0	0	2
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	2	0	2
Solute carrier organic anion transporter family member 2B1	0	4	0	4
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	2	0	2
Interleukin-8	0	1	0	1
Androgen receptor	0	2	1	3
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	3
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Thromboxane-A synthase	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Caspase-1	0	1	0	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	2
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	3	3
Aldo-keto reductase family 1 member C3	0	2	0	2
Histamine H2 receptor	7	0	0	7
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Guanine nucleotide-binding protein G	2	0	0	2
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	3
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Sigma intracellular receptor 2	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Solute carrier organic anion transporter family member 1B1	0	5	0	7
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	5	0	0	5
Amyloid-beta precursor protein	0	3	0	3
Sodium/myo-inositol cotransporter 2	0	1	0	1
histone deacetylase 9 isoform 3	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	5	0	0	5
Ornithine decarboxylase	0	0	0	2
Adenosine receptor A3	0	4	0	4
Retinoic acid receptor alpha	0	2	2	4
Alpha-1B adrenergic receptor	0	4	0	4
Retinoic acid receptor gamma	0	2	2	4
Retinoic acid receptor beta	0	2	2	4
Cellular retinoic acid-binding protein 2	0	0	2	2
Mitogen-activated protein kinase 1	0	3	3	6
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	2	0	3
5-hydroxytryptamine receptor 2B	0	4	0	4
Alpha-1A adrenergic receptor	0	5	0	5
Cellular retinoic acid-binding protein 1	0	0	2	2
Mitogen-activated protein kinase 14	0	2	3	5
Estrogen receptor beta	0	1	0	2
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	2	0	2
Cytochrome P450 26A1	0	1	0	1
Camphor 5-monooxygenase	0	0	0	1
Epoxide hydrolase 1	0	0	0	1
Aldo-keto reductase family 1 member B1	0	5	0	5
Cytochrome P450 2C11	0	1	0	1
Steroid 21-hydroxylase	0	1	0	1
Cytochrome P450 2C8	0	2	0	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Cytochrome P450 2A2	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Translocator protein	0	1	0	1
Cytochrome P450 7A1	0	1	0	1
Estrogen receptor	0	1	0	2
Substance-K receptor	0	2	0	2
Sodium-dependent noradrenaline transporter	0	4	0	4
Histamine H2 receptor	0	2	0	2
Gonadotropin-releasing hormone receptor	0	3	1	4
Sodium-dependent serotonin transporter	0	2	0	2
Type-1 angiotensin II receptor	0	1	0	1
Delta-type opioid receptor	0	2	0	2
Cytochrome P450 4F2	0	1	0	1
Sodium-dependent dopamine transporter	0	4	0	4
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	2	0	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Cytochrome P450 7A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Cytochrome P450 1A1	0	2	0	2
Cytochrome P450 1A2	0	4	1	5
Cytochrome P450 2C19	0	3	1	4
Cytochrome P450 1B1	0	1	0	1
matrix metalloproteinase 1, partial	0	0	1	1
nonstructural protein 1	4	0	0	4
pyruvate kinase	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Endothelin receptor type B	1	0	0	1
Endothelin-1 receptor	1	0	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	3	0	3
Phospholipase A-2-activating protein	0	3	0	3
Gonadotropin-releasing hormone receptor	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Lysophosphatidic acid receptor 6	0	0	1	1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	2	0	2
Lysophosphatidic acid receptor 4	0	0	1	1
Lysophosphatidic acid receptor 1	0	0	2	2
Lysophosphatidic acid receptor 4	0	0	1	1
Lysophosphatidic acid receptor 5	0	0	1	1
Lysophosphatidic acid receptor 2	0	0	1	1
Lysophosphatidic acid receptor 3	0	0	1	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
Dihydrofolate reductase	0	5	0	6
Dipeptidyl peptidase 4	0	2	0	2
Solute carrier family 22 member 1	0	0	0	1
Solute carrier family 22 member 8	0	1	0	1
Polyphenol oxidase 2	0	3	0	6
Dopamine beta-hydroxylase	0	2	0	2
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	4	4
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	3
5-hydroxytryptamine receptor 2C	0	1	0	2
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	1	4	5
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
streptokinase A precursor	0	0	2	2
Trypsin	0	0	0	1
DNA gyrase subunit A	0	1	0	2
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit B	0	2	0	3
DNA gyrase subunit A	0	2	0	3
Bone morphogenetic protein receptor type-1B	0	0	3	3
Membrane-associated progesterone receptor component 1	0	0	2	2
Serine/threonine-protein kinase PLK4	0	0	3	3
ATP-dependent RNA helicase DDX3X	0	0	3	3
Pyridoxal kinase	0	0	3	3
Citron Rho-interacting kinase	0	0	3	3
Serine/threonine-protein kinase Chk1	0	1	3	4
Aurora kinase A	0	0	3	3
Cyclin-G-associated kinase	0	0	3	3
Ephrin type-B receptor 6	0	0	3	3
Peroxisomal acyl-coenzyme A oxidase 3	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 2	0	0	3	3
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	3	3
Dynamin-like 120 kDa protein, mitochondrial	0	0	3	3
Tyrosine-protein kinase JAK2	0	3	4	9
Eukaryotic translation initiation factor 5B	0	0	2	2
Rho-associated protein kinase 2	0	1	3	4
Serine/threonine-protein kinase ULK1	0	0	3	3
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	3	3
Ribosomal protein S6 kinase alpha-5	0	1	3	4
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	3	3
Ribosomal protein S6 kinase alpha-4	0	0	3	3
Serine/threonine-protein kinase 16	0	0	3	3
Serine/threonine-protein kinase 10	0	0	3	3
Serine/threonine-protein kinase D3	0	0	3	3
Structural maintenance of chromosomes protein 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 6	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	3	3
Serine/threonine-protein kinase LATS1	0	0	3	3
Serine/threonine-protein kinase PAK 4	0	0	3	3
High affinity nerve growth factor receptor	0	0	3	3
ADP/ATP translocase 2	0	0	3	3
Protein kinase C beta type	0	0	3	3
Insulin receptor	0	1	3	4
Tyrosine-protein kinase Lck	0	1	3	4
Tyrosine-protein kinase Fyn	0	0	3	3
Glycogen phosphorylase, liver form	0	0	3	3
Tyrosine-protein kinase Fes/Fps	0	0	3	3
Adenine phosphoribosyltransferase	0	0	2	2
Tyrosine-protein kinase Yes	0	0	3	3
Tyrosine-protein kinase Lyn	0	0	3	3
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	3	3
Insulin-like growth factor 1 receptor	0	0	3	3
Signal recognition particle receptor subunit alpha	0	0	3	3
Cytochrome c1, heme protein, mitochondrial	0	0	3	3
Hepatocyte growth factor receptor	0	0	3	3
Tyrosine-protein kinase HCK	0	0	3	3
Platelet-derived growth factor receptor beta	0	0	3	3
Tyrosine-protein kinase Fgr	0	0	3	3
Serine/threonine-protein kinase A-Raf	0	0	3	3
Glycogen phosphorylase, brain form	0	0	3	3
Breakpoint cluster region protein	0	0	3	3
Serine/threonine-protein kinase pim-1	0	0	3	3
Fibroblast growth factor receptor 1	0	0	3	3
Cyclin-dependent kinase 4	0	0	3	3
ADP/ATP translocase 3	0	0	3	3
Inosine-5'-monophosphate dehydrogenase 2	0	0	2	2
Proto-oncogene tyrosine-protein kinase Src	0	0	3	3
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	2	2
Serine/threonine-protein kinase B-raf	0	1	3	4
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	3	3
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	3	3
Tyrosine-protein kinase Fer	0	0	3	3
Protein kinase C alpha type	0	1	3	4
cAMP-dependent protein kinase catalytic subunit alpha	0	0	3	3
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	3	3
Casein kinase II subunit alpha'	0	0	3	3
Ras-related protein Rab-6A	0	0	3	3
Ephrin type-A receptor 1	0	0	3	3
Multifunctional protein ADE2	0	0	3	3
cAMP-dependent protein kinase catalytic subunit gamma	0	0	2	2
cAMP-dependent protein kinase catalytic subunit beta	0	0	3	3
Ferrochelatase, mitochondrial	0	0	3	3
Ribosomal protein S6 kinase beta-1	0	1	3	4
Tyrosine-protein kinase JAK1	0	3	4	9
Beta-adrenergic receptor kinase 1	0	0	3	3
Probable ATP-dependent RNA helicase DDX6	0	0	3	3
Mitogen-activated protein kinase 3	0	0	3	3
MAP/microtubule affinity-regulating kinase 3	0	0	3	3
Deoxycytidine kinase	0	0	3	3
Ephrin type-A receptor 2	0	0	3	3
Ephrin type-B receptor 2	0	0	3	3
Non-receptor tyrosine-protein kinase TYK2	0	3	4	9
Wee1-like protein kinase	0	0	3	3
Heme oxygenase 2	0	0	3	3
DnaJ homolog subfamily A member 1	0	0	3	3
RAC-alpha serine/threonine-protein kinase	0	1	3	4
RAC-beta serine/threonine-protein kinase	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Dual specificity protein kinase TTK	0	0	3	3
DNA replication licensing factor MCM4	0	0	2	2
Myosin-10	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 2	0	1	3	4
Receptor-type tyrosine-protein kinase FLT3	0	0	3	3
Bone morphogenetic protein receptor type-1A	0	0	3	3
Activin receptor type-1B	0	0	3	3
TGF-beta receptor type-1	0	0	3	3
Serine/threonine-protein kinase receptor R3	0	0	3	3
TGF-beta receptor type-2	0	0	3	3
Electron transfer flavoprotein subunit beta	0	0	2	2
Tyrosine-protein kinase CSK	0	1	3	4
Glycine--tRNA ligase	0	0	3	3
Mitogen-activated protein kinase kinase kinase 8	0	1	0	1
Protein kinase C iota type	0	0	3	3
Exosome RNA helicase MTR4	0	0	3	3
Tyrosine-protein kinase Tec	0	1	3	4
Tyrosine-protein kinase ABL2	0	0	3	3
Tyrosine-protein kinase FRK	0	0	3	3
G protein-coupled receptor kinase 6	0	0	2	2
Tyrosine-protein kinase SYK	0	0	3	3
26S proteasome regulatory subunit 6B	0	0	3	3
Mitogen-activated protein kinase 8	0	1	3	4
Mitogen-activated protein kinase 9	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 4	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 3	0	0	3	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	2	2
Casein kinase I isoform alpha	0	0	3	3
Casein kinase I isoform delta	0	0	3	3
MAP kinase-activated protein kinase 2	0	1	3	4
Elongation factor Tu, mitochondrial	0	0	3	3
Choline-phosphate cytidylyltransferase A	0	0	2	2
Cysteine--tRNA ligase, cytoplasmic	0	0	3	3
Casein kinase I isoform epsilon	0	0	3	3
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	3	3
Dual specificity protein kinase CLK1	0	0	3	3
Dual specificity protein kinase CLK2	0	0	3	3
Dual specificity protein kinase CLK3	0	0	3	3
Glycogen synthase kinase-3 alpha	0	0	3	3
Glycogen synthase kinase-3 beta	0	1	3	4
Cyclin-dependent kinase 7	0	0	3	3
Cyclin-dependent kinase 9	0	0	3	3
Ras-related protein Rab-27A	0	0	2	2
Interleukin-1 receptor-associated kinase 1	0	0	3	3
Ribosomal protein S6 kinase alpha-3	0	1	3	4
Serine/threonine-protein kinase Nek2	0	0	3	3
Serine/threonine-protein kinase Nek3	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 6	0	0	3	3
Serine/threonine-protein kinase PLK1	0	0	3	3
LIM domain kinase 1	0	0	3	3
LIM domain kinase 2	0	0	3	3
Mitogen-activated protein kinase 10	0	0	3	3
Tyrosine--tRNA ligase, cytoplasmic	0	0	3	3
5'-AMP-activated protein kinase subunit gamma-1	0	0	3	4
Ephrin type-B receptor 3	0	0	3	3
Ephrin type-A receptor 5	0	0	3	3
Ephrin type-B receptor 4	0	0	3	3
Ephrin type-A receptor 4	0	0	3	3
Adenylate kinase 2, mitochondrial	0	0	3	3
Adenosine kinase	0	0	3	3
Ras-related protein Rab-10	0	0	3	3
Actin-related protein 3	0	0	3	3
Actin-related protein 2	0	0	2	2
GTP-binding nuclear protein Ran	0	0	3	3
Casein kinase I isoform gamma-2	0	0	3	3
Cyclin-dependent kinase 3	0	0	2	2
Cyclin-dependent kinase 6	0	0	3	3
Cyclin-dependent-like kinase 5	0	1	3	4
Cyclin-dependent kinase 16	0	0	3	3
Cyclin-dependent kinase 17	0	0	3	3
ATP-dependent 6-phosphofructokinase, platelet type	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 1	0	1	3	4
Protein kinase C theta type	0	0	3	3
Activin receptor type-1	0	0	3	3
Macrophage-stimulating protein receptor	0	0	3	3
Focal adhesion kinase 1	0	0	3	3
Protein kinase C delta type	0	0	3	3
Tyrosine-protein kinase BTK	0	1	3	4
Activated CDC42 kinase 1	0	0	3	3
Epithelial discoidin domain-containing receptor 1	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	3	3
Tyrosine-protein kinase Mer	0	0	3	3
Serine/threonine-protein kinase 4	0	0	3	3
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	3	4
Dual specificity mitogen-activated protein kinase kinase 5	0	0	3	3
Mitogen-activated protein kinase 7	0	0	3	3
Serine/threonine-protein kinase PAK 2	0	0	3	3
Serine/threonine-protein kinase 3	0	0	3	3
Mitogen-activated protein kinase kinase kinase 1	0	0	3	3
Integrin-linked protein kinase	0	0	3	3
Rho-associated protein kinase 1	0	0	3	3
Non-receptor tyrosine-protein kinase TNK1	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	3	3
Activin receptor type-2B	0	0	3	3
Bone morphogenetic protein receptor type-2	0	0	3	3
Protein-tyrosine kinase 6	0	0	3	3
cGMP-dependent protein kinase 1	0	0	3	3
Cyclin-dependent kinase 13	0	0	3	3
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	3	3
Protein-tyrosine kinase 2-beta	0	0	3	3
Maternal embryonic leucine zipper kinase	0	0	3	3
Structural maintenance of chromosomes protein 1A	0	0	2	2
Chromodomain-helicase-DNA-binding protein 4	0	0	3	3
Peroxisomal acyl-coenzyme A oxidase 1	0	0	2	2
Delta(24)-sterol reductase	0	0	2	2
Ribosomal protein S6 kinase alpha-1	0	0	3	3
Dual specificity testis-specific protein kinase 1	0	0	3	3
Myosin light chain kinase, smooth muscle	0	0	3	3
Mitogen-activated protein kinase 11	0	1	3	4
Serine/threonine-protein kinase STK11	0	0	3	3
Serine/threonine-protein kinase N1	0	0	3	3
Serine/threonine-protein kinase N2	0	0	3	3
Calcium/calmodulin-dependent protein kinase type IV	0	0	3	3
Mitogen-activated protein kinase kinase kinase 11	0	0	3	3
MAP kinase-activated protein kinase 3	0	0	1	1
AP2-associated protein kinase 1	0	0	3	3
Myosin light chain kinase 3	0	0	3	3
Uncharacterized aarF domain-containing protein kinase 5	0	0	3	3
Putative heat shock protein HSP 90-beta 2	0	0	3	3
Rab-like protein 3	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	3	3
Serine/threonine-protein kinase MRCK gamma	0	0	3	3
Acyl-CoA dehydrogenase family member 10	0	0	3	3
Serine/threonine-protein kinase N3	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	3	3
Uncharacterized protein FLJ45252	0	0	3	3
Acyl-CoA dehydrogenase family member 11	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	3	3
Serine/threonine-protein kinase MARK2	0	0	3	3
ATP-dependent RNA helicase DHX30	0	0	3	3
Serine/threonine-protein kinase TAO1	0	0	3	3
STE20-related kinase adapter protein alpha	0	0	3	3
Myosin-14	0	0	3	3
AarF domain-containing protein kinase 1	0	0	3	3
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	3	3
MAP kinase-activated protein kinase 5	0	1	3	4
Misshapen-like kinase 1	0	0	3	3
Atypical kinase COQ8A, mitochondrial	0	0	3	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	3	3
Mitogen-activated protein kinase 15	0	0	3	3
Serine/threonine-protein kinase Nek9	0	0	3	3
Serine/threonine-protein kinase Nek7	0	0	2	2
ATP-dependent RNA helicase DDX1	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	3	3
Aurora kinase B	0	0	3	3
MAP/microtubule affinity-regulating kinase 4	0	0	3	3
Serine/threonine-protein kinase Nek1	0	0	3	3
PAS domain-containing serine/threonine-protein kinase	0	0	3	3
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	3	3
EKC/KEOPS complex subunit TP53RK	0	0	3	3
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	3	3
Mitogen-activated protein kinase kinase kinase 5	0	0	3	3
Mitogen-activated protein kinase kinase kinase 3	0	0	3	3
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	3	3
Nucleolar GTP-binding protein 1	0	0	3	3
Serine/threonine-protein kinase D2	0	0	3	3
NUAK family SNF1-like kinase 2	0	0	2	2
RNA cytidine acetyltransferase	0	0	3	3
Serine/threonine-protein kinase SIK2	0	0	3	3
STE20-like serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase TAO3	0	0	3	3
dCTP pyrophosphatase 1	0	0	3	3
Dual specificity protein kinase CLK4	0	0	3	3
Casein kinase I isoform gamma-1	0	0	3	3
Serine/threonine-protein kinase PAK 6	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	3	3
BMP-2-inducible protein kinase	0	0	3	3
Obg-like ATPase 1	0	0	2	2
Interleukin-1 receptor-associated kinase 4	0	0	3	3
Mitogen-activated protein kinase kinase kinase 20	0	0	3	3
Cyclin-dependent kinase 12	0	0	3	3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	2	2
Serine/threonine-protein kinase pim-2	0	0	2	2
Serine/threonine-protein kinase 26	0	0	3	3
Serine/threonine-protein kinase NLK	0	0	3	3
5'-AMP-activated protein kinase subunit gamma-2	0	0	3	4
Serine/threonine-protein kinase TBK1	0	1	3	4
Septin-9	0	0	3	3
Ribosomal protein S6 kinase alpha-6	0	0	3	3
TRAF2 and NCK-interacting protein kinase	0	0	3	3
Serine/threonine-protein kinase TAO2	0	0	3	3
Serine/threonine-protein kinase ICK	0	0	3	3
RAC-gamma serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase SIK3	0	0	3	3
Mitogen-activated protein kinase kinase kinase 2	0	0	3	3
Thyroid hormone receptor-associated protein 3	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 3	0	0	3	3
Serine/threonine-protein kinase MRCK beta	0	0	3	3
Interleukin-1 receptor-associated kinase 3	0	0	3	3
Serine/threonine-protein kinase 24	0	0	3	3
Casein kinase I isoform gamma-3	0	0	3	3
Mitogen-activated protein kinase kinase kinase 4	0	0	3	3
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Cytochrome P450 2B6	0	2	1	3
Sodium-dependent serotonin transporter	0	1	0	1
Muscarinic acetylcholine receptor M4	0	0	1	2
Delta-type opioid receptor	0	0	0	1
Kappa-type opioid receptor	0	0	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Mu-type opioid receptor	0	0	0	1
Cholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	3
Monocarboxylate transporter 10	0	0	0	3
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	1	0	0	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Phenylethanolamine N-methyltransferase	0	0	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Alpha-1A adrenergic receptor	0	0	1	1
Gamma-aminobutyric acid	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Cytochrome P450 2A6	0	3	1	4
Muscarinic acetylcholine receptor DM1	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	2	2
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Glutamate 5-kinase	0	0	0	1
Angiotensin-converting enzyme	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
NADH-cytochrome b5 reductase 3	0	1	0	1
Thyroid peroxidase	0	1	0	1
Taste receptor type 2 member 38	0	0	1	2
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Alpha-synuclein	1	3	0	4
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	2
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	1	0	2
Glutathione S-transferase omega-1	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	1	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	1	1	2
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Acetylcholinesterase	0	1	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	2
Xanthine dehydrogenase/oxidase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Acetylcholinesterase	0	1	0	1
Pyruvate kinase PKM	0	0	1	1
Cholinesterase	0	1	0	1
Cell division cycle 7-related protein kinase	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	2	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	2	2
Serine/threonine-protein kinase mTOR	0	1	2	3
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Protein kinase C zeta type	0	0	1	1
Cyclin-dependent kinase 18	0	0	2	2
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Programmed cell death protein 4	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	2	2
Dual specificity testis-specific protein kinase 2	0	0	2	2
Target of rapamycin complex subunit LST8	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
Midasin	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	2	2
Beta-2 adrenergic receptor	0	2	1	3
Beta-1 adrenergic receptor	0	2	1	3
Beta-3 adrenergic receptor	0	1	1	2
POU domain, class 2, transcription factor 1	0	0	0	1
Beta-2 adrenergic receptor	0	1	0	1
Beta-2 adrenergic receptor	0	0	1	1
Cereblon isoform 4	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	2	1	4
Cytochrome P450 2B1	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidine phosphorylase	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Transthyretin	0	1	0	2
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	2	4	6
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Chain A, Tyrosine-protein kinase	0	1	0	1
Chain A, Tyrosine-protein kinase	0	1	0	1
Chain A, Tyrosine-protein kinase JAK2	0	1	0	1
Leukotriene C4 synthase	0	0	1	1
tyrosine-protein kinase Yes	1	0	0	1
Serine/threonine-protein kinase Sgk1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	0	1	1
Serine/threonine-protein kinase 25	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	1	1
Serine/threonine-protein kinase RIO3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 7	0	1	1	2
Peripheral plasma membrane protein CASK	0	0	1	1
Serine/threonine-protein kinase DCLK1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	1	1
Muscle, skeletal receptor tyrosine-protein kinase	0	0	1	1
Mitogen-activated protein kinase 13	0	1	1	2
3-phosphoinositide-dependent protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 13	0	0	1	1
Death-associated protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
NUAK family SNF1-like kinase 1	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	1	1
Serine/threonine-protein kinase PAK 3	0	0	1	1
Serine/threonine-protein kinase 17B	0	0	1	1
Cyclin-dependent kinase 14	0	0	1	1
Serine/threonine-protein kinase OSR1	0	0	1	1
Serine/threonine-protein kinase Chk2	0	0	1	1
RAF proto-oncogene serine/threonine-protein kinase	0	0	1	1
Receptor tyrosine-protein kinase erbB-2	0	1	1	2
Macrophage colony-stimulating factor 1 receptor	0	0	1	1
Proto-oncogene tyrosine-protein kinase ROS	0	0	1	1
Wee1-like protein kinase 2	0	0	1	1
Uncharacterized serine/threonine-protein kinase SBK3	0	0	1	1
Mast/stem cell growth factor receptor Kit	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Insulin receptor-related protein	0	0	1	1
Platelet-derived growth factor receptor alpha	0	0	1	1
Vascular endothelial growth factor receptor 1	0	0	1	1
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	1	1
Serine/threonine-protein kinase MAK	0	0	1	1
Cyclin-dependent kinase 11B	0	0	1	1
Fibroblast growth factor receptor 2	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	0	1	1
Fibroblast growth factor receptor 4	0	0	1	1
Fibroblast growth factor receptor 3	0	0	1	1
Protein kinase C eta type	0	0	1	1
Activin receptor type-2A	0	0	1	1
Ephrin type-A receptor 3	0	0	1	1
Ephrin type-A receptor 8	0	0	1	1
Leukocyte tyrosine kinase receptor	0	0	1	1
Tyrosine-protein kinase receptor UFO	0	0	1	1
Mitogen-activated protein kinase 4	0	0	1	1
G protein-coupled receptor kinase 4	0	0	1	1
Tyrosine-protein kinase receptor Tie-1	0	0	1	1
Vascular endothelial growth factor receptor 3	0	0	1	1
Vascular endothelial growth factor receptor 2	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	0	1	1
Megakaryocyte-associated tyrosine-protein kinase	0	0	1	1
Tyrosine-protein kinase TXK	0	1	1	2
Tyrosine-protein kinase ZAP-70	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	0	1	1
Cyclin-dependent kinase 8	0	0	1	1
Tyrosine-protein kinase Blk	0	1	1	2
Cytoplasmic tyrosine-protein kinase BMX	0	1	1	2
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek4	0	0	1	1
Tyrosine-protein kinase JAK3	0	3	2	8
Death-associated protein kinase 1	0	0	1	1
Mitogen-activated protein kinase 12	0	1	1	2
Ephrin type-B receptor 1	0	0	1	1
Hormonally up-regulated neu tumor-associated kinase	0	0	1	1
Serine/threonine-protein kinase SIK1	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 4	0	0	1	1
Cell division control protein 2 homolog	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
Tubulin alpha-1A chain	0	0	1	1
Casein kinase II subunit alpha	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	1	1
SRSF protein kinase 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 9	0	0	1	1
Serine/threonine-protein kinase PknB	0	0	1	1
Cyclin-dependent kinase-like 1	0	0	1	1
Protein kinase C epsilon type	0	0	1	1
Mitogen-activated protein kinase kinase kinase 10	0	0	1	1
Tyrosine-protein kinase receptor TYRO3	0	0	1	1
Tyrosine-protein kinase ITK/TSK	0	1	1	2
Myotonin-protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 12	0	0	1	1
Serine/threonine-protein kinase PAK 1	0	0	1	1
cGMP-dependent protein kinase 2	0	0	1	1
Serine/threonine-protein kinase PRP4 homolog	0	0	1	1
Serine/threonine-protein kinase ATR	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1	0	0	1	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
Serine/threonine-protein kinase D1	0	0	1	1
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	1	1	2
Ribosomal protein S6 kinase alpha-2	0	0	1	1
Ephrin type-A receptor 7	0	0	1	1
Rhodopsin kinase GRK1	0	0	1	1
NT-3 growth factor receptor	0	0	1	1
BDNF/NT-3 growth factors receptor	0	0	1	1
Mitogen-activated protein kinase 6	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 19	0	0	1	1
Serine/threonine-protein kinase TNNI3K	0	0	1	1
Tyrosine-protein kinase JAK3	0	1	0	1
Tyrosine-protein kinase JAK2	0	1	0	1
Tyrosine-protein kinase JAK3	0	1	0	1
Serine/threonine-protein kinase Nek5	0	0	1	1
Dual serine/threonine and tyrosine protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 15	0	0	1	1
Serine/threonine-protein kinase tousled-like 2	0	0	1	1
Serine/threonine-protein kinase 32C	0	0	1	1
Serine/threonine-protein kinase pim-3	0	0	1	1
Serine/threonine-protein kinase VRK2	0	0	1	1
Myosin light chain kinase family member 4	0	0	1	1
Homeodomain-interacting protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1D	0	0	1	1
Cyclin-dependent kinase-like 3	0	0	1	1
Serine/threonine-protein kinase BRSK2	0	0	1	1
Serine/threonine-protein kinase NIM1	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	1	1
Serine/threonine-protein kinase DCLK2	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	1	1
Casein kinase I isoform alpha-like	0	0	1	1
Homeodomain-interacting protein kinase 4	0	0	1	1
Myosin-IIIa	0	0	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	1	1
Serine/threonine-protein kinase Nek11	0	0	1	1
Serine/threonine-protein kinase BRSK1	0	0	1	1
Serine/threonine-protein kinase 35	0	0	1	1
Rhodopsin kinase GRK7	0	0	1	1
Serine/threonine-protein kinase 32A	0	0	1	1
Myosin-IIIb	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	1	1
Cyclin-dependent kinase-like 2	0	0	1	1
Serine/threonine-protein kinase Sgk3	0	0	1	1
Atypical kinase COQ8B, mitochondrial	0	0	1	1
Cyclin-dependent kinase 15	0	0	1	1
SRSF protein kinase 1	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	1	1
Serine/threonine-protein kinase RIO1	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO2	0	0	1	1
Cyclin-dependent kinase 19	0	0	1	1
Transient receptor potential cation channel subfamily M member 6	0	0	1	1
Testis-specific serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 33	0	0	1	1
Serine/threonine-protein kinase DCLK3	0	0	1	1
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	1	1
Homeodomain-interacting protein kinase 2	0	0	1	1
Tyrosine-protein kinase Srms	0	0	1	1
Homeodomain-interacting protein kinase 3	0	0	1	1
Serine/threonine-protein kinase PLK3	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	1	1
Serine/threonine-protein kinase Nek6	0	0	1	1
SNF-related serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase LATS2	0	0	1	1
Serine/threonine-protein kinase 36	0	0	1	1
Serine/threonine-protein kinase 32B	0	0	1	1
Serine/threonine-protein kinase PLK2	0	0	1	1
Serine/threonine-protein kinase MARK1	0	0	1	1
Serine/threonine-protein kinase PAK 5	0	0	1	1
eIF-2-alpha kinase GCN2	0	0	1	1
Phosphatidylinositol 4-kinase beta	0	0	1	1
Serine/threonine-protein kinase 17A	0	0	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	1	1
Ephrin type-A receptor 6	0	0	1	1
Death-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase tousled-like 1	0	0	1	1
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
ALK tyrosine kinase receptor	0	0	1	1
SRSF protein kinase 3	0	0	1	1
Cyclin-dependent kinase 11A	0	0	1	1
Aurora kinase C	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	1	1
Serine/threonine-protein kinase 38-like	0	0	1	1
Microtubule-associated serine/threonine-protein kinase 1	0	0	1	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
60 kDa chaperonin	0	1	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor RXR-beta	0	2	2	4
Nuclear receptor ROR-alpha	0	1	0	1
Retinoic acid receptor RXR-gamma	0	2	2	4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Chain A, Arginase 1	0	1	0	1
Cocaine esterase	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	2
UDP-glucuronosyltransferase 1-6	0	0	0	1
Liver carboxylesterase 1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Adenosylhomocysteinase	0	1	0	1
RNA-directed RNA polymerase	0	1	1	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
twin arginine protein translocation system - TatA protein	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Anhidrotic Ectodermal Dysplasia

Synonyms(21)

Research Excerpts

Overview

Actions

Treatment

Research

Studies (520)

Protein Targets (1,555)

Anhidrotic Ectodermal Dysplasia

Synonyms(21)

Research Excerpts

Overview

Actions

Treatment

Research

Studies (520)

Drugs Studied (170)

Protein Targets (1,555)