Page last updated: 2024-09-28

Umbilical Cyst

Cyst occurring in a persistent portion of the urachus, presenting as an extraperitoneal mass in the umbilical region. It is characterized by abdominal pain, and fever if infected. It may rupture, leading to peritonitis, or it may drain through the umbilicus.

Synonyms(2)

Synonym
Umbilical Cyst
Urachal Cyst

Research Excerpts

Research

Studies (19)

TimeframeStudies, This Condition (%)All Conditions %
pre-19901 (5.26)23.3326
1990's2 (10.53)12.5806
2000's6 (31.58)18.1394
2010's8 (42.11)28.8240
2020's2 (10.53)9.53
DrugIndicatedRelationship StrengthStudiesTrials
fluorouracil0low10
guaifenesin0low10
indomethacin0low10
ketamine0low10
metronidazole0low10
praziquantel0low10
methylene blue0low10
ampicillin0low10
penicillanic acid0low10
pyrazolanthrone0low10
perfluorodecanoic acid0low10
deoxycytidine0low10
cladribine0low10
carbenicillin0low10
floxacillin0low10
cephalexin0low10
piperacillin0low10
gemcitabine0low10
cephalosporin c0low10
tazobactam0low10
fosfomycin0low10
dinoprostone0low10
pulmicort0low10
bay 11-70820low10
amoxicillin-potassium clavulanate combination0low10
protectin d10low10
ro13-99040low10
sodium pertechnetate tc 99m0low10
resolvin D40low10
resolvin d30low10
levoleucovorin0low10

Protein Targets (517)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE7007
Chain A, Mutant Al2 6e7p9g0011
Chain A, Beta-lactamase2002
Chain A, 2-oxoglutarate Oxygenase4004
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Chain A, Cruzipain3003
Beta-lactamase 0203
acid sphingomyelinase2002
GLS protein4004
GLI family zinc finger 37007
apical membrane antigen 1, AMA12002
retinoic acid nuclear receptor alpha variant 18008
farnesoid X nuclear receptor7007
Beta-lactamase 0002
Beta-lactamase 0103
Metallo-beta-lactamase type 20002
Metallo-beta-lactamase VIM-11 0001
euchromatic histone-lysine N-methyltransferase 28008
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0002
Metallo-beta-lactamase0001
Beta-lactamase 0002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
chromobox protein homolog 14004
thyroid hormone receptor beta isoform 29009
DNA polymerase beta3003
DNA polymerase eta isoform 13003
DNA polymerase iota isoform a (long)4004
geminin100010
DNA polymerase kappa isoform 13003
Carbonic anhydrase 10101
Carbonic anhydrase 20101
60 kDa heat shock protein, mitochondrial0101
Beta-lactamase OXA-70002
Solute carrier family 15 member 10707
Solute carrier family 15 member 10202
Spike glycoprotein3014
10 kDa heat shock protein, mitochondrial0101
Angiopoietin-1 receptor0011
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 15 member 20202
Thiosulfate sulfurtransferase0101
Metallo-beta-lactamase VIM-130002
Efflux transporter 0001
Beta-lactamase 0103
Beta-lactamase Toho-10001
Beta-lactamase 0001
Class D beta-lactamase0104
60 kDa chaperonin 0101
Metallo-beta-lactamase0001
Solute carrier family 15 member 20203
Beta-lactamase 0103
Beta-lactamase 0001
10 kDa chaperonin 0101
Metallo-b-lactamase 0004
Carbapenem-hydrolyzing beta-lactamase KPC0204
Histamine H3 receptor0002
Beta-lactamase class B VIM-2 0004
Beta-lactamase VIM-1 0002
ATP-dependent phosphofructokinase7007
Chain A, TYROSYL-DNA PHOSPHODIESTERASE3003
Chain A, Putative fructose-1,6-bisphosphate aldolase5005
thioredoxin reductase5005
phosphopantetheinyl transferase4004
ATAD5 protein, partial3003
Fumarate hydratase3003
TDP1 protein110011
Microtubule-associated protein tau6006
aldehyde dehydrogenase 1 family, member A16006
hypothetical protein, conserved2002
regulator of G-protein signaling 44004
estrogen-related nuclear receptor alpha9009
polyprotein3003
Parkin3003
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
Replicase polyprotein 1ab0112
NPC intracellular cholesterol transporter 1 precursor2002
D(1A) dopamine receptor1001
vitamin D3 receptor isoform VDRA7007
atrial natriuretic peptide receptor 2 precursor1001
ras-related protein Rab-9A2002
serine/threonine-protein kinase mTOR isoform 14004
nuclear receptor ROR-gamma isoform 14004
histone acetyltransferase KAT2A isoform 11001
Amyloid-beta precursor protein2103
Replicase polyprotein 1ab0112
Nuclear factor NF-kappa-B p105 subunit0101
Alpha-synuclein2002
Nuclear factor NF-kappa-B p100 subunit 0101
Transcription factor p650101
NACHT, LRR and PYD domains-containing protein 3 0101
Ataxin-25005
Class A sortase SrtA 0101
RAR-related orphan receptor gamma6006
estrogen nuclear receptor alpha110011
Liver carboxylesterase 10001
Dihydroxyacetone phosphate acyltransferase0001
Solute carrier family 22 member 60505
B2 metallo-beta-lactamase 0002
Chain A, JmjC domain-containing histone demethylation protein 3A2002
Luciferase5005
Smad33003
glucocorticoid receptor [Homo sapiens]8008
cytochrome P450 2D64004
nuclear factor erythroid 2-related factor 2 isoform 19009
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
lamin isoform A-delta108008
Multidrug resistance-associated protein 40709
Solute carrier family 22 member 60203
Solute carrier family 22 member 80203
Solute carrier family 22 member 110102
Solute carrier family 22 member 80202
bromodomain adjacent to zinc finger domain 2B3003
mitogen-activated protein kinase 16006
Interferon beta7007
Chain A, BCL-2-RELATED PROTEIN A10011
glp-1 receptor, partial4004
AR protein9009
nuclear receptor subfamily 1, group I, member 34004
EWS/FLI fusion protein6006
retinoid X nuclear receptor alpha8008
pregnane X nuclear receptor7007
G4004
67.9K protein4004
peroxisome proliferator-activated receptor delta5005
IDH13003
Histone H2A.x4004
cellular tumor antigen p53 isoform a2002
nuclear factor erythroid 2-related factor 2 isoform 24004
huntingtin isoform 23003
tyrosine-protein kinase Yes1001
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
survival motor neuron protein isoform d5005
muscleblind-like protein 1 isoform 16006
relaxin receptor 1 isoform 11001
bcl-2-like protein 11 isoform 10011
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
ATP-binding cassette sub-family C member 30707
Bile salt export pump011011
HLA class I histocompatibility antigen, B alpha chain 4004
Cellular tumor antigen p539009
Integrin beta-31001
Integrin alpha-IIb1001
Deoxycytidine kinase0003
Adenosine receptor A30101
Rap guanine nucleotide exchange factor 41001
Inositol hexakisphosphate kinase 14004
Canalicular multispecific organic anion transporter 10707
ATPase family AAA domain-containing protein 54004
cytochrome P450 2C9, partial4004
Thymidine kinase 2 0101
Probable deoxycytidylate deaminase0001
Cytidine deaminase0002
AAA family ATPase 0002
Reverse transcriptase/RNaseH 0011
SMAD family member 26006
SMAD family member 36006
thyroid stimulating hormone receptor4004
thyroid stimulating hormone receptor2002
activating transcription factor 63003
prostaglandin E2 receptor EP2 subtype1001
peripheral myelin protein 222002
Solute carrier family 22 member 20001
Solute carrier family 22 member 1 0001
Solute carrier organic anion transporter family member 1A50001
Cytochrome P450 3A40011
Prostaglandin E2 receptor EP3 subtype0202
Prostaglandin E2 receptor EP4 subtype0202
Prostaglandin E2 receptor EP1 subtype0213
Prostaglandin E2 receptor EP1 subtype0202
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin F2-alpha receptor0011
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP3 subtype0213
Prostaglandin E2 receptor EP2 subtype0213
Prostacyclin receptor0213
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 70002
Prostaglandin E2 receptor EP2 subtype0202
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Solute carrier family 22 member 70001
Solute carrier organic anion transporter family member 2A10001
Solute carrier organic anion transporter family member 1B20001
Solute carrier family 22 member 70001
Bile salt export pump0202
Chain A, Uracil Phosphoribosyltransferase0101
interleukin 82002
endonuclease IV2002
acetylcholinesterase2002
Skn7p0001
pregnane X receptor1001
hypoxia-inducible factor 1 alpha subunit4004
Thrombopoietin3003
estrogen receptor 2 (ER beta)6006
progesterone receptor4004
nonstructural protein 11001
peroxisome proliferator activated receptor gamma5005
arylsulfatase A3003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a5005
v-jun sarcoma virus 17 oncogene homolog (avian)3003
peripheral myelin protein 22 isoform 13003
hemoglobin subunit beta1001
flap endonuclease 14004
Vpr2002
Voltage-dependent calcium channel gamma-2 subunit4004
Solute carrier family 22 member 80001
Epidermal growth factor receptor0202
Thymidylate synthase0101
Aromatase0101
Glutamate receptor 24004
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0101
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0101
Chain A, DEOXYNUCLEOSIDE KINASE0101
Spike glycoprotein0011
Transmembrane protease serine 20011
Procathepsin L0112
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Equilibrative nucleoside transporter 10101
Angiotensin-converting enzyme 2 0011
Rap guanine nucleotide exchange factor 32002
Chain A, membrane-associated prostaglandin E synthase-20101
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
cytochrome P450 family 3 subfamily A polypeptide 45005
glucocerebrosidase2002
vitamin D (1,25- dihydroxyvitamin D3) receptor3003
aryl hydrocarbon receptor6006
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
cytochrome P450 2D6 isoform 12002
cytochrome P450 2C9 precursor2002
thyroid hormone receptor beta isoform a3003
heat shock protein beta-12002
M-phase phosphoprotein 82002
neuropeptide S receptor isoform A3003
Prostaglandin-H2 D-isomerase0101
Prostaglandin E synthase0101
Prostaglandin G/H synthase 1 0102
Prostaglandin G/H synthase 2 0102
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0202
Cytochrome c oxidase subunit 20101
Phospholipase A2, major isoenzyme0101
Albumin0112
Prostaglandin G/H synthase 10203
ATP-dependent translocase ABCB10101
Neuronal acetylcholine receptor subunit alpha-40101
Interleukin-80101
Androgen receptor0011
Neuronal acetylcholine receptor subunit beta-20101
Polyunsaturated fatty acid 5-lipoxygenase0102
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Prostaglandin G/H synthase 10101
Sodium-dependent dopamine transporter0101
Sodium- and chloride-dependent GABA transporter 10101
Thromboxane-A synthase 0101
Adenosine receptor A10101
Serum paraoxonase/arylesterase 10101
Indoleamine 2,3-dioxygenase 10101
Caspase-10001
Nitric oxide synthase, inducible0101
Adenosine receptor A2a0101
Substance-P receptor0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Multidrug resistance-associated protein 1 0101
Bifunctional epoxide hydrolase 20101
Prostaglandin G/H synthase 20213
Prostaglandin G/H synthase 2 0101
Peroxisome proliferator-activated receptor gamma0011
Aldo-keto reductase family 1 member C30202
Histamine H2 receptor2002
Sodium- and chloride-dependent betaine transporter0101
C-X-C chemokine receptor type 30101
Nuclear receptor ROR-gamma1001
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G3003
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30101
Prostaglandin G/H synthase 20202
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10101
Prostaglandin G/H synthase 20102
Potassium voltage-gated channel subfamily H member 20101
Uracil nucleotide/cysteinyl leukotriene receptor0101
Sigma intracellular receptor 20101
Rho-associated protein kinase 20101
Prostaglandin G/H synthase 1 0101
Nicotinate phosphoribosyltransferase0101
Multidrug and toxin extrusion protein 10101
Dehydrogenase/reductase SDR family member 90101
P2Y purinoceptor 120101
Solute carrier organic anion transporter family member 1B30202
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Solute carrier organic anion transporter family member 1B10202
Glutamate receptor ionotropic, NMDA 2D0101
Acetylcholinesterase0101
Glutamate receptor ionotropic, NMDA 3B0101
Glutamate receptor ionotropic, NMDA 1 0202
Sodium channel protein type 4 subunit alpha0101
Cholinesterase0101
Glutamate receptor ionotropic, NMDA 2A 0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0202
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 2D0202
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0202
Glutamate receptor ionotropic, NMDA 3A0202
Chain E, Fibrin beta chain0101
Chain A, Ferritin light chain2002
T cell receptor, partial1001
luteinizing hormone receptor1001
integrase, partial0101
chaperonin-containing TCP-1 beta subunit homolog1001
lens epithelium-derived growth factor p750101
Caspase 6, apoptosis-related cysteine peptidase0001
PPM1D protein3003
TSHR protein1001
Apoptotic peptidase activating factor 10101
thioredoxin glutathione reductase1001
caspase 7, apoptosis-related cysteine protease1001
isocitrate dehydrogenase 1, partial1001
luciferase1001
caspase-31001
serine-protein kinase ATM isoform a1001
Bloom syndrome protein isoform 12002
neutrophil cytosol factor 10101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
caspase-9 isoform alpha precursor0101
histone deacetylase 9 isoform 31001
pyruvate kinase PKM isoform a1001
caspase-3 isoform a preproprotein0101
protein AF-9 isoform a0001
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
replicative DNA helicase0001
recombinase A0011
POsterior Segregation0011
DNA repair protein RAD52 homolog isoform a0001
Glutathione reductase0101
Glutathione reductase, mitochondrial0102
Glycoprotein hormones alpha chain1001
Albumin0001
Dihydrolipoyl dehydrogenase, mitochondrial0102
Microtubule-associated protein tau0112
Alpha-1B adrenergic receptor0101
Amine oxidase [flavin-containing] A0101
Alpha-1D adrenergic receptor0101
Sodium-dependent noradrenaline transporter 0011
Cruzipain0101
Alpha-1A adrenergic receptor0101
Inositol monophosphatase 11001
TAR DNA-binding protein 433003
Thioredoxin reductase 1, cytoplasmic0102
Dihydrolipoyl dehydrogenase 0102
Zinc finger protein mex-50011
phosphoglycerate kinase1001
Thioredoxin reductase 0101
Flavodoxin0001
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Lanosterol 14-alpha demethylase0101
Beta-lactamase 0102
Beta-lactamase 0102
Beta-lactamase 0102
Beta-lactamase 0001
Beta-lactamase 0102
Beta-lactamase 0001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0102
Beta-lactamase SHV-10102
Beta-lactamase SHV-10203
Beta-lactamase0102
Kappa-type opioid receptor0001
Beta-lactamase 0102
Beta-lactamase 0102
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Beta-lactamase 0102
Beta-lactamase 0001
BlaVIM-1 0001
Beta-lactamase 0001
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b0011
nuclear receptor subfamily 1, group I, member 22002
cytochrome P450 3A4 isoform 13003
muscarinic acetylcholine receptor M11001
Gamma-aminobutyric acid receptor subunit pi3003
Gamma-aminobutyric acid receptor subunit beta-13003
Gamma-aminobutyric acid receptor subunit delta3003
Gamma-aminobutyric acid receptor subunit gamma-23003
Gamma-aminobutyric acid receptor subunit alpha-53003
Gamma-aminobutyric acid receptor subunit alpha-33003
Gamma-aminobutyric acid receptor subunit gamma-13003
Gamma-aminobutyric acid receptor subunit alpha-23003
Gamma-aminobutyric acid receptor subunit alpha-43003
Gamma-aminobutyric acid receptor subunit gamma-33003
Gamma-aminobutyric acid receptor subunit alpha-63003
Gamma-aminobutyric acid receptor subunit alpha-13003
Gamma-aminobutyric acid receptor subunit beta-33003
Gamma-aminobutyric acid receptor subunit beta-23003
GABA theta subunit3003
Gamma-aminobutyric acid receptor subunit epsilon3003
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
NFKB1 protein, partial1001
Estrogen receptor0101
Glucocorticoid receptor0213
Interleukin-50101
Interleukin-50101
Progesterone receptor0101
Glucocorticoid receptor0101
Glycine receptor subunit alpha-10202
Mineralocorticoid receptor 0112
Matrix metalloproteinase-90101
Androgen receptor0202
Glycine receptor subunit beta0202
Interleukin-5 receptor subunit alpha0101
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Sodium-dependent serotonin transporter0101
Estrogen receptor beta0101
Chain A, Mitogen-activated protein kinase 100101
Chain A, Mitogen-activated protein kinase 100101
Chain A, Mitogen-activated protein kinase 100101
RGS121001
TPA: protein transporter TIM100101
TPA: protein transporter TIM230101
atrial natriuretic peptide receptor 1 precursor1001
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 11001
importin subunit beta-1 isoform 11001
polyadenylate-binding protein 10101
snurportin-11001
GTP-binding nuclear protein Ran isoform 11001
caspase-1 isoform alpha precursor1001
lethal factor (plasmid)1001
Serine/threonine-protein kinase PLK40011
Aurora kinase A0011
Cyclin-G-associated kinase0011
3-phosphoinositide-dependent protein kinase 10011
Death-associated protein kinase 30011
Serine/threonine-protein kinase/endoribonuclease IRE10101
Ribosomal protein S6 kinase alpha-50011
Serine/threonine-protein kinase 160011
Renin0101
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Interferon-induced, double-stranded RNA-activated protein kinase0101
Cyclin-dependent kinase 20011
Ephrin type-A receptor 30011
Dual specificity protein kinase TTK0112
Mitogen-activated protein kinase 80112
Mitogen-activated protein kinase 90112
Casein kinase I isoform epsilon0011
Dual specificity protein kinase CLK20011
Tyrosine-protein kinase JAK30101
Mitogen-activated protein kinase 120011
Mitogen-activated protein kinase 100112
Caspase-71001
Cyclin-dependent kinase 160011
Serine/threonine-protein kinase 40011
Calcium/calmodulin-dependent protein kinase type 10011
Ribosomal protein S6 kinase alpha-20011
Mitogen-activated protein kinase 140101
AP2-associated protein kinase 10011
Serine/threonine-protein kinase ULK30011
Serine/threonine-protein kinase MARK20011
Calcium/calmodulin-dependent protein kinase type 1D0011
Calcium/calmodulin-dependent protein kinase type 1G0011
Calcium/calmodulin-dependent protein kinase kinase 20011
Single-stranded DNA cytosine deaminase1001
STE20-like serine/threonine-protein kinase 0011
Dual specificity protein kinase CLK40011
MAP kinase-interacting serine/threonine-protein kinase 20011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase 30011
BMP-2-inducible protein kinase0011
Serine/threonine-protein kinase pim-20011
Serine/threonine-protein kinase 17A0011
Death-associated protein kinase 20011
TRAF2 and NCK-interacting protein kinase0011
Aurora kinase C0011
Serine/threonine-protein kinase 38-like0011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Beta-lactamase 0101
Beta-lactamase 0101
B2 bradykinin receptor0101
Beta-lactamase0101
Beta-lactamase0101
Beta-lactamase0101
Beta-lactamase0101
Beta-lactamase0203
Beta-lactamase OXA-10102
5-hydroxytryptamine receptor 1A0101
Cytochrome P450 2B60101
Metallo-beta-lactamase type 20101
Angiotensin-converting enzyme0101
Metallo-beta-lactamase L1 type 30101
Beta-lactamase TEM0202
Beta-lactamase0101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase 0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]