A tumor composed of cells resembling those of the hair matrix, which undergo 'mummification' and may calcify. It is a relatively uncommon tumor, which may occur at any age from infancy. The majority of patients are under 20, and females are affected more than males. The lesion is usually a solitary deep dermal or subcutaneous tumor 3-30 mm in diameter, situated in the head, neck, or upper extremity. (From Rook et al., Textbook of Dermatology, 4th ed, p2401)
| Excerpt | Reference |
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| "Human pilomatricomas are benign epidermal appendage tumors composed of hair matrix-like basaloid cells and keratinized remnant cells referred to as shadow cells." | ( Asada, H; Hirota, S; Ito, A; Kitamura, Y; Kohri, K; Nomura, S; Tsukamoto, Y; Xu, Z; Yoshikawa, K, 1995) |
| "Pilomatrixoma is a benign tumor of hair follicles that usually occurs as a single tumor and appears in the head and neck region, extremities, and trunk." | ( Fridman, E; Migirov, L; Talmi, YP, 2002) |
| "Pilomatrixoma is a benign skin neoplasm of the hair follicle." | ( Boutayeb, F; Daoudi, A; El Ibrahimi, A; Elmrini, A; Znati, K, 2009) |
| "Pilomatricoma is believed to differentiate towards the hair matrix and hair cortex." | ( Kimura, T; Kurokawa, I; Mizutani, H; Senba, Y; Sugisaki, H; Tsubura, A; Yamanaka, K, 2009) |
| "Pilomatricoma is a rare, benign skin neoplasm that originates from hair matrix cells and is most frequently located in the head and neck region." | ( Delank, KW; Deutsch, J; Trick, D, 2010) |
| "Pilomatricoma is a common benign neoplasm of the skin characterized by a solid cutaneous nodule of hair matrix origin." | ( Chen, J; Fang, K; Jin, H; Li, L; Ray, H; Xiao, Y; Zeng, Y, 2012) |
| "Pilomatricoma is uncommon in adults and an unusual cause for marked FDG uptake, likely due to foreign body inflammation." | ( Bhatt, MK; Ravi Kumar, AS; Sommerville, R, 2012) |
| "Pilomatricoma is a relatively common benign skin neoplasm originating from the hair follicle matrix cells." | ( Brito, C; Duarte, Mda L; Gomes, J; Resende, CI, 2013) |
| "Pilomatricoma is a tumour derived from hair matrix cells, which shows progressive keratin expression." | ( Buettner, R; Fink, D; Friedrichs, J; Friedrichs, N; Hartmann, W; Kindler, D; Mauch, C; Schüle, R, 2015) |
| "Pilomatricoma is a rare benign tumor of the hair follicle matrix cells, which associates during its evolution a foreign body-like inflammatory process." | ( Cianga, CM; Cianga, P; Dumitrescu, GF; Sava, A, 2016) |
| "Pilomatricomas are benign calcifying neoplasms derived from follicle matrix cells." | ( Maranda, EL; Riyaz, F; Shwayder, T, 2017) |
| "Pilomatricomas are benign tumors of the hair follicle that occur frequently in the scalp region." | ( Akbari, SHA; Cochran, E; Lane, JR, 2023) |